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How do you solve a solution like the Northern Ireland Protocol? – politicalbetting.com

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Comments

  • CharlesCharles Posts: 35,758
    Alistair said:

    Floater said:
    Agent P struggling with figures again.

    1 million doses hadn't even been delivered to Scotland by the end of January.
    Doesn’t mean that he’s struggling with figures. It would be a reasonable excuse for not hitting the target
  • Luckyguy1983Luckyguy1983 Posts: 28,477
    edited February 2021
    Alistair said:

    Floater said:
    Agent P struggling with figures again.

    1 million doses hadn't even been delivered to Scotland by the end of January.
    What was delivered is irrelevant. The vaccines are held centrally and then ordered up as needed by the rollout teams in each nation. If those vaccines were not available to be ordered by Scotland, of course that's a good reason to miss the target. If they were, the fact that they were 'sitting in a warehouse in England' just means the rollout in Scotland was slower than promised as Agent P suggests.
  • FoxyFoxy Posts: 48,710
    Charles said:

    I thought AZ was supposed to have 12 weeks between doses not 28 days?
    The 3 main studies on AZN in UK, Brazil and SA all used different dosage regimes (2 in the UK with the accidental half dose) including different gaps and different placebos. It is why it is hard to combine them into one.
  • FairlieredFairliered Posts: 4,939
    ydoethur said:

    ydoethur said:

    Andy_JS said:

    Bloody black people coming over here and taking over our gospel singing

    https://twitter.com/GreensladeR/status/1358469502908907520?s=20

    Gospel singing originated in the Outer Hebrides.
    Stor? No way!
    Barra-load of bollocks......
    Stop Harrising people.
    Or Islay tell on ya!
    Oh, ban them and be done with it. It’s Morar less the same in the end.
    This is a Rhum thread. In fact, it’s getting quite mucky. Anyway, I canna stay, the eigg man’s at the door.
  • ydoethurydoethur Posts: 71,421

    ydoethur said:

    ydoethur said:

    Andy_JS said:

    Bloody black people coming over here and taking over our gospel singing

    https://twitter.com/GreensladeR/status/1358469502908907520?s=20

    Gospel singing originated in the Outer Hebrides.
    Stor? No way!
    Barra-load of bollocks......
    Stop Harrising people.
    Or Islay tell on ya!
    Oh, ban them and be done with it. It’s Morar less the same in the end.
    This is a Rhum thread. In fact, it’s getting quite mucky. Anyway, I canna stay, the eigg man’s at the door.
    Don’t Loch him out.
  • AnabobazinaAnabobazina Posts: 23,486
    Floater said:
    Who is this Agent P? He comes across as a complete wanker. His tweets are really irritating a la Dave Keating.
  • ydoethurydoethur Posts: 71,421
    Well, whatever the weather here, at least one country is being bitten by the Beast:

    Storm Darcy: Netherlands hit by 'first major snowstorm in decade'
    https://www.bbc.co.uk/news/world-europe-55970665

    We had one brief hailstorm in Cannock.

    Slightly unfortunate I had gone out for a walk, and was caught in he middle of it, but these things happen.
  • ydoethur said:

    kinabalu said:

    @Theuniondivvie

    Hang on though - sure that's not a spoof?

    Well, I have been wondering. I mean, surely nobody can be quite so bizarrely stereotypical cybernat as he comes across as, particularly in his increasingly xenophobic attacks on other poste...

    Oh hold on - did you mean TUV not TUD?
    What do you think a DUP mp has to do with the TUV?
  • MaxPBMaxPB Posts: 38,865
    Charles said:

    I thought AZ was supposed to have 12 weeks between doses not 28 days?
    I think the 12 week findings came much more recently than the start of this trial so they used the default 4 weeks. Would be interesting to see how it does with a 12 week gap given that efficacy goes up to 83% from 55% once the gap increases from 4 weeks to 12 weeks.
  • ydoethurydoethur Posts: 71,421

    ydoethur said:

    kinabalu said:

    @Theuniondivvie

    Hang on though - sure that's not a spoof?

    Well, I have been wondering. I mean, surely nobody can be quite so bizarrely stereotypical cybernat as he comes across as, particularly in his increasingly xenophobic attacks on other poste...

    Oh hold on - did you mean TUV not TUD?
    What do you think a DUP mp has to do with the TUV?
    About sixty thousand?

    Or are they going for a cut price these days?
  • AlistairAlistair Posts: 23,670

    Alistair said:

    Floater said:
    Agent P struggling with figures again.

    1 million doses hadn't even been delivered to Scotland by the end of January.
    What was delivered is irrelevant. The vaccines are held centrally and then ordered up as needed by the rollout teams in each nation. If those vaccines were not available to be ordered by Scotland, of course that's a good reason to miss the target. If they were, the fact that they were 'sitting in a warehouse in England' just means the rollout in Scotland was slower than promised as Agent P suggests.
    So you are saying Scotland could order the UK's entire stock of vaccine at the drop of a hat?
  • Charles said:

    Charles said:

    MattW said:

    Charles said:

    ydoethur said:

    DIY experts of PB. I was wondering if you could help me.

    Does anyone know what could have caused this mark appearing on the wall of my house? The house was built circa 3 years ago.

    It certainly feels like its caused by moisture as paint comes off when you touch it but nothing looks amiss outside on the brickwork.



    When it happened in mine, it was a leaking gutter.
    For me the mortar was shot and the lead flashing light.
    Pivoting, is that inside or outside?
    The damage was in the inside but the ingress was via the chimney stack
    That sounds expensive to fix. Or is it?
    $2k because I caught it early fortunately
    You lucked out, methinks. Could have been a lot worse.
  • AlistairAlistair Posts: 23,670
    edited February 2021

    Floater said:
    Who is this Agent P? He comes across as a complete wanker. His tweets are really irritating a la Dave Keating.
    They're a leading light in the Yooneverse. Always ready with a numerically incontinent tweet that gets repeated as fact.

    Last week he was counjouring up an extra thousand Scottish deaths or so, a few weeks before claiming that a 1-in-100 was a higher infection rate than a 1-in-95 figure.
  • ydoethur said:

    ydoethur said:

    Andy_JS said:

    Bloody black people coming over here and taking over our gospel singing

    https://twitter.com/GreensladeR/status/1358469502908907520?s=20

    Gospel singing originated in the Outer Hebrides.
    Stor? No way!
    Barra-load of bollocks......
    Stop Harrising people.
    Or Islay tell on ya!
    Oh, ban them and be done with it. It’s Morar less the same in the end.
    This is a Rhum thread. In fact, it’s getting quite mucky. Anyway, I canna stay, the eigg man’s at the door.
    The Skye's the limit!
  • TheuniondivvieTheuniondivvie Posts: 41,996
    edited February 2021
    Alistair said:

    Floater said:
    Who is this Agent P? He comes across as a complete wanker. His tweets are really irritating a la Dave Keating.
    They're a leading light in the Yooneverse. Always ready with a numerically incontinent tweet that gets repeated as fact.

    Last week he was counjouring up and extra thousand Scottish deaths or so, a few weeks before claiming that a 1-in-100 was a higher infection rate than a 1-in-95 figure.
    It's a strange day when the same people who tweet Agent Pee incontinently are also spraying WoS links all over the place. Then you see who the people are and you think fair enough.
  • MaxPBMaxPB Posts: 38,865
    Foxy said:

    Charles said:

    I thought AZ was supposed to have 12 weeks between doses not 28 days?
    The 3 main studies on AZN in UK, Brazil and SA all used different dosage regimes (2 in the UK with the accidental half dose) including different gaps and different placebos. It is why it is hard to combine them into one.
    I wonder whether having a proper P2 trial would have helped AZ figure out the 12 week dosing gap as they could have tested immune responses in P2 with 4, 8, 12 and 16 week gaps as well as the single dose with groups of 300-500 people starting as soon as the safety trial ended in April, though maybe the 16 week gap would have been axed for reasons of speed. With a fast recruitment process they would still have caught the start of the second wave with fully 20-30k vaccinated people and got the results at around the same time as they did but with a much less messy dataset, plus with a larger P2 the reticence to recruit as many 65+ people would have fallen away.

    The trial AZ conducted was a complete mess, different placebos, variable dosing gaps, not enough over 65s, the low dose fuck up. It was just so badly run for something that has such a huge amount of importance. Hopefully the US trial and real world data start to clear things up in the next few weeks. Especially once our over 65s start to receive their second doses. We can easily compare them to the unvaccinated within our own county, the sample size will be massive.
  • CarnyxCarnyx Posts: 42,879

    ydoethur said:

    ydoethur said:

    Andy_JS said:

    Bloody black people coming over here and taking over our gospel singing

    https://twitter.com/GreensladeR/status/1358469502908907520?s=20

    Gospel singing originated in the Outer Hebrides.
    Stor? No way!
    Barra-load of bollocks......
    Stop Harrising people.
    Or Islay tell on ya!
    Oh, ban them and be done with it. It’s Morar less the same in the end.
    This is a Rhum thread. In fact, it’s getting quite mucky. Anyway, I canna stay, the eigg man’s at the door.
    The Skye's the limit!
    All a bit Mucky if you ask me. It all adds to the Sgurr of the Unionists on the wrong side of the ledger.
  • ydoethurydoethur Posts: 71,421
    Carnyx said:

    ydoethur said:

    ydoethur said:

    Andy_JS said:

    Bloody black people coming over here and taking over our gospel singing

    https://twitter.com/GreensladeR/status/1358469502908907520?s=20

    Gospel singing originated in the Outer Hebrides.
    Stor? No way!
    Barra-load of bollocks......
    Stop Harrising people.
    Or Islay tell on ya!
    Oh, ban them and be done with it. It’s Morar less the same in the end.
    This is a Rhum thread. In fact, it’s getting quite mucky. Anyway, I canna stay, the eigg man’s at the door.
    The Skye's the limit!
    All a bit Mucky if you ask me. It all adds to the Sgurr of the Unionists on the wrong side of the ledger.
    Very good, but for all Argyll in punning, I am off to bed.

    Have a good evening.
  • CarnyxCarnyx Posts: 42,879
    edited February 2021

    kinabalu said:

    If we can reduce the lethality of Covid to that of a bad flu, we are fine. The vulnerable can be offered a vaccine yearly.

    Yep. But I'd say a wider vaccination than that.
    What is ludicrous to me is that a simple blood test would show that most of us are significantly deficient in key minerals and vitamins vs. internationally agreed (by Doctors) norms. This makes us vulnerable to infectious disease (as well as chronic disease, which increases year on year) - but there's no discussion about this in official circles. Instead of increasing our rubustness, academics and policy makers think a future as mask-wearing weaklings that need constant jabbing is an acceptable notion. I am not a 'Covid-denier', but it must be springboard to better health for everyone, not a trap door to mass medical dependency.
    I must admit this business has got me taking vitD tablets (at the moderate rate generally recommended), being a Scot in the twilit winter, despite eating more than my fair share of mackerel, salmon, eggs and milk.
  • AlwaysSingingAlwaysSinging Posts: 464
    edited February 2021
    Foxy said:

    31 years old. I wouldn't have expected hospitalisation or death in that group, so probably why couldn't be commented on.
    That study is underpowered. The vaccine efficacy confidence interval (against B.1.351) was -78.8% to +54.8%. It would be a mistake to read too much into it, at this point.

    The data on re-infection is a little bit more robust, though: if antibody presence from past infection confers immunity to B.1.351 then it can't be a huge amount. That's a more worrying finding. Good reason to try to keep this variant out of the UK, or suppress it hard.

    And yes, the study has nothing to say about serious illness. I wonder what they were thinking when they recruited for it. Underpowered medical trials are a real problem for science, and lead to bad policy.

    --AS

    Edit: and, to follow up on reinfection, the same finding happened in the Novavax trial. So I think that conclusion is becoming more firm.
  • I have the autobiography of the bomb disposal officer that day - its a great great read.
  • MalmesburyMalmesbury Posts: 50,357
    Carnyx said:

    kinabalu said:

    If we can reduce the lethality of Covid to that of a bad flu, we are fine. The vulnerable can be offered a vaccine yearly.

    Yep. But I'd say a wider vaccination than that.
    What is ludicrous to me is that a simple blood test would show that most of us are significantly deficient in key minerals and vitamins vs. internationally agreed (by Doctors) norms. This makes us vulnerable to infectious disease (as well as chronic disease, which increases year on year) - but there's no discussion about this in official circles. Instead of increasing our rubustness, academics and policy makers think a future as mask-wearing weaklings that need constant jabbing is an acceptable notion. I am not a 'Covid-denier', but it must be springboard to better health for everyone, not a trap door to mass medical dependency.
    I must admit this business has got me taking vitD tablets (at the moderate rate generally recommended), being a Scot in the twilit winter, despite eating more than my fair share of mackerel, salmon, eggs and milk.
    "mask-wearing weaklings that need constant jabbing"

    Hmmmm

    Well, some people might think that. Or they might think that modern medicine and precautions beats Social Darwinism.

    All these weaklings, insisting on drains and potable water, anesthetics for their operations, antibiotics when they get a perfectly normal case of gangrene......
  • CarnyxCarnyx Posts: 42,879

    Alistair said:

    Floater said:
    Who is this Agent P? He comes across as a complete wanker. His tweets are really irritating a la Dave Keating.
    They're a leading light in the Yooneverse. Always ready with a numerically incontinent tweet that gets repeated as fact.

    Last week he was counjouring up and extra thousand Scottish deaths or so, a few weeks before claiming that a 1-in-100 was a higher infection rate than a 1-in-95 figure.
    It's a strange day when the same people who tweet Agent Pee incontinently are also spraying WoS links all over the place. Then you see who the people are and you think fair enough.
    I'm not sure who would be more black affrontit at being mentioned almost in the same approbatory breath by Carlotta et aliis.
  • CarnyxCarnyx Posts: 42,879

    I have the autobiography of the bomb disposal officer that day - its a great great read.
    https://www.amazon.co.uk/Braver-Walk-Away-Peter-Gurney/dp/0002550512

    That one? Yes, it is.
  • FoxyFoxy Posts: 48,710
    MaxPB said:

    Foxy said:

    Charles said:

    I thought AZ was supposed to have 12 weeks between doses not 28 days?
    The 3 main studies on AZN in UK, Brazil and SA all used different dosage regimes (2 in the UK with the accidental half dose) including different gaps and different placebos. It is why it is hard to combine them into one.
    I wonder whether having a proper P2 trial would have helped AZ figure out the 12 week dosing gap as they could have tested immune responses in P2 with 4, 8, 12 and 16 week gaps as well as the single dose with groups of 300-500 people starting as soon as the safety trial ended in April, though maybe the 16 week gap would have been axed for reasons of speed. With a fast recruitment process they would still have caught the start of the second wave with fully 20-30k vaccinated people and got the results at around the same time as they did but with a much less messy dataset, plus with a larger P2 the reticence to recruit as many 65+ people would have fallen away.

    The trial AZ conducted was a complete mess, different placebos, variable dosing gaps, not enough over 65s, the low dose fuck up. It was just so badly run for something that has such a huge amount of importance. Hopefully the US trial and real world data start to clear things up in the next few weeks. Especially once our over 65s start to receive their second doses. We can easily compare them to the unvaccinated within our own county, the sample size will be massive.
    I think that in such circumstances as last year the trials were rather rushed for all the vaccines, but even amongst those the AZN was a bit of a mess. Fortunately the virus seems particularly susceptible to vaccines so most work, and have few significant side effects. We had a full on anaphylaxis with a Pfizer at a local vaccination station last week, but that seems to be very rare given the numbers.

    Increasingly it will be unethical to have a placebo arm in vaccine trials, so I expect that new vaccines will be tested against current vaccines for non-inferiority studies. The numbers to get statistical power will mean much larger trials.

    The other thing to look out for are treatment trials. I am optimistic for SNG001 developed at Southampton University, which should work for all respiratory viruses, not just covid. So much so, that I have punted on some SNG shares, but not so much that I couldn't afford it if it flops.
  • Luckyguy1983Luckyguy1983 Posts: 28,477
    Alistair said:

    Alistair said:

    Floater said:
    Agent P struggling with figures again.

    1 million doses hadn't even been delivered to Scotland by the end of January.
    What was delivered is irrelevant. The vaccines are held centrally and then ordered up as needed by the rollout teams in each nation. If those vaccines were not available to be ordered by Scotland, of course that's a good reason to miss the target. If they were, the fact that they were 'sitting in a warehouse in England' just means the rollout in Scotland was slower than promised as Agent P suggests.
    So you are saying Scotland could order the UK's entire stock of vaccine at the drop of a hat?
    Not at all, but the Scotland rollout team could have ordered up Scotland's full allocation over this time. We can surmise what that might have been by looking at the fastest vaccinating nation (don't know who it was by Feb 1) and seeing how many they did. Scotland's allocation would not have been less than 9% of that.
  • MalmesburyMalmesbury Posts: 50,357
    edited February 2021
    Carnyx said:

    I have the autobiography of the bomb disposal officer that day - its a great great read.
    https://www.amazon.co.uk/Braver-Walk-Away-Peter-Gurney/dp/0002550512

    That one? Yes, it is.
    obligatory image....

    image
  • CarnyxCarnyx Posts: 42,879

    Carnyx said:

    kinabalu said:

    If we can reduce the lethality of Covid to that of a bad flu, we are fine. The vulnerable can be offered a vaccine yearly.

    Yep. But I'd say a wider vaccination than that.
    What is ludicrous to me is that a simple blood test would show that most of us are significantly deficient in key minerals and vitamins vs. internationally agreed (by Doctors) norms. This makes us vulnerable to infectious disease (as well as chronic disease, which increases year on year) - but there's no discussion about this in official circles. Instead of increasing our rubustness, academics and policy makers think a future as mask-wearing weaklings that need constant jabbing is an acceptable notion. I am not a 'Covid-denier', but it must be springboard to better health for everyone, not a trap door to mass medical dependency.
    I must admit this business has got me taking vitD tablets (at the moderate rate generally recommended), being a Scot in the twilit winter, despite eating more than my fair share of mackerel, salmon, eggs and milk.
    "mask-wearing weaklings that need constant jabbing"

    Hmmmm

    Well, some people might think that. Or they might think that modern medicine and precautions beats Social Darwinism.

    All these weaklings, insisting on drains and potable water, anesthetics for their operations, antibiotics when they get a perfectly normal case of gangrene......
    Not to mention freedom from typhus-bearing lice, tuberculotically crowded conditions and so on. I was recently quite startled to discover that my late father born in the 1920s had had a life policy taken out at birth by his not very well off mother to pay the funeral costs. evidently if he went down with one of the many childhood infections. He didn't, and it was quite a job dividing the payout between all of granny's descendants.
  • Alistair said:

    Alistair said:

    Floater said:
    Agent P struggling with figures again.

    1 million doses hadn't even been delivered to Scotland by the end of January.
    What was delivered is irrelevant. The vaccines are held centrally and then ordered up as needed by the rollout teams in each nation. If those vaccines were not available to be ordered by Scotland, of course that's a good reason to miss the target. If they were, the fact that they were 'sitting in a warehouse in England' just means the rollout in Scotland was slower than promised as Agent P suggests.
    So you are saying Scotland could order the UK's entire stock of vaccine at the drop of a hat?
    Not at all, but the Scotland rollout team could have ordered up Scotland's full allocation over this time. We can surmise what that might have been by looking at the fastest vaccinating nation (don't know who it was by Feb 1) and seeing how many they did. Scotland's allocation would not have been less than 9% of that.
    Fastest is currently England - 24.3 doses/100 vs Scotland19.2.
  • PulpstarPulpstar Posts: 78,204
    We push out the common/garden vaccine whilst pursuing the variant ruthlessly.
  • AnabobazinaAnabobazina Posts: 23,486
    I’m the first to criticise LuckyGuy usually, but he clearly wasn’t referring literally to humans being weaklings. What he was saying - to my reading - was that a blood test could be developed to assess who was susceptible to covid. That seems like a fair point to me.
  • Luckyguy1983Luckyguy1983 Posts: 28,477

    Carnyx said:

    kinabalu said:

    If we can reduce the lethality of Covid to that of a bad flu, we are fine. The vulnerable can be offered a vaccine yearly.

    Yep. But I'd say a wider vaccination than that.
    What is ludicrous to me is that a simple blood test would show that most of us are significantly deficient in key minerals and vitamins vs. internationally agreed (by Doctors) norms. This makes us vulnerable to infectious disease (as well as chronic disease, which increases year on year) - but there's no discussion about this in official circles. Instead of increasing our rubustness, academics and policy makers think a future as mask-wearing weaklings that need constant jabbing is an acceptable notion. I am not a 'Covid-denier', but it must be springboard to better health for everyone, not a trap door to mass medical dependency.
    I must admit this business has got me taking vitD tablets (at the moderate rate generally recommended), being a Scot in the twilit winter, despite eating more than my fair share of mackerel, salmon, eggs and milk.
    "mask-wearing weaklings that need constant jabbing"

    Hmmmm

    Well, some people might think that. Or they might think that modern medicine and precautions beats Social Darwinism.

    All these weaklings, insisting on drains and potable water, anesthetics for their operations, antibiotics when they get a perfectly normal case of gangrene......
    That's a ludicrous straw man argument. I think we should make use of every wonderful benefit that building on the experience of our forebears can provide. These do not include (as a long term vision) standing two meters apart from everyone, covering the face, and being dependent on ever-changing vaccines merely to live.

    If you're such a fan of modern medicine, what could be more scientific than highlighting (using science) serious nutritional deficiencies and trying to do something about them? It is considerably more scientific an approach than telling people to 'lose weight'. The carrying of energy as fat is not, in and of itself even a disease.
  • MalmesburyMalmesbury Posts: 50,357
    The thing I find strange is that anyone tries with Putin. It is quite clear that he sees the world in terms of the sheep and the wolf.
  • FoxyFoxy Posts: 48,710

    Foxy said:

    31 years old. I wouldn't have expected hospitalisation or death in that group, so probably why couldn't be commented on.
    That study is underpowered. The vaccine efficacy confidence interval (against B.1.351) was -78.8% to +54.8%. It would be a mistake to read too much into it, at this point.

    The data on re-infection is a little bit more robust, though: if antibody presence from past infection confers immunity to B.1.351 then it can't be a huge amount. That's a more worrying finding. Good reason to try to keep this variant out of the UK, or suppress it hard.

    And yes, the study has nothing to say about serious illness. I wonder what they were thinking when they recruited for it. Underpowered medical trials are a real problem for science, and lead to bad policy.

    --AS

    Edit: and, to follow up on reinfection, the same finding happened in the Novavax trial. So I think that conclusion is becoming more firm.
    I understood it to be a further follow up of the original AZN trial in RSA (Cov005) reported in the Lancet in November. That had 2096 enrolled, with a 4 week interval and allowing for a bit of dropout leaving 1749 for this analysis.



  • The thing I find strange is that anyone tries with Putin. It is quite clear that he sees the world in terms of the sheep and the wolf.
    This episode was particularly humiliating, not only did the Russians quote his SputnikV comments in a video contradicting Navalny, he wasn't 5 minutes out the door and they were expelling EU diplomats....
  • MalmesburyMalmesbury Posts: 50,357

    Carnyx said:

    kinabalu said:

    If we can reduce the lethality of Covid to that of a bad flu, we are fine. The vulnerable can be offered a vaccine yearly.

    Yep. But I'd say a wider vaccination than that.
    What is ludicrous to me is that a simple blood test would show that most of us are significantly deficient in key minerals and vitamins vs. internationally agreed (by Doctors) norms. This makes us vulnerable to infectious disease (as well as chronic disease, which increases year on year) - but there's no discussion about this in official circles. Instead of increasing our rubustness, academics and policy makers think a future as mask-wearing weaklings that need constant jabbing is an acceptable notion. I am not a 'Covid-denier', but it must be springboard to better health for everyone, not a trap door to mass medical dependency.
    I must admit this business has got me taking vitD tablets (at the moderate rate generally recommended), being a Scot in the twilit winter, despite eating more than my fair share of mackerel, salmon, eggs and milk.
    "mask-wearing weaklings that need constant jabbing"

    Hmmmm

    Well, some people might think that. Or they might think that modern medicine and precautions beats Social Darwinism.

    All these weaklings, insisting on drains and potable water, anesthetics for their operations, antibiotics when they get a perfectly normal case of gangrene......
    That's a ludicrous straw man argument. I think we should make use of every wonderful benefit that building on the experience of our forebears can provide. These do not include (as a long term vision) standing two meters apart from everyone, covering the face, and being dependent on ever-changing vaccines merely to live.

    If you're such a fan of modern medicine, what could be more scientific than highlighting (using science) serious nutritional deficiencies and trying to do something about them? It is considerably more scientific an approach than telling people to 'lose weight'. The carrying of energy as fat is not, in and of itself even a disease.
    It's not about "merely to live" - so that an *increasing* number of people continue to live. That whole progress thing.

    The claim that vitamin D deficiency increases COVID susceptibility hasn't been proven in any study.
  • IshmaelZIshmaelZ Posts: 21,830

    kinabalu said:

    If we can reduce the lethality of Covid to that of a bad flu, we are fine. The vulnerable can be offered a vaccine yearly.

    Yep. But I'd say a wider vaccination than that.
    What is ludicrous to me is that a simple blood test would show that most of us are significantly deficient in key minerals and vitamins vs. internationally agreed (by Doctors) norms. This makes us vulnerable to infectious disease (as well as chronic disease, which increases year on year) - but there's no discussion about this in official circles. Instead of increasing our rubustness, academics and policy makers think a future as mask-wearing weaklings that need constant jabbing is an acceptable notion. I am not a 'Covid-denier', but it must be springboard to better health for everyone, not a trap door to mass medical dependency.
    Where is your evidence for that? Here

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060686/#!po=0.746269

    is a survey from 2018 showing that almost everybody is getting more than enough of almost everything. And - this is the best bit - 22% of their sample were taking supplements but they ignored those and just looked at what people are getting from their diet. Nutrition is great, but it doesn't "boost your immune system" and it is nothing to do with protecting yourself from viruses - masks and vaccines do that. The one exception is vitamin D and "official circles" are very far from silent about that.
  • Luckyguy1983Luckyguy1983 Posts: 28,477
    edited February 2021

    I’m the first to criticise LuckyGuy usually, but he clearly wasn’t referring literally to humans being weaklings. What he was saying - to my reading - was that a blood test could be developed to assess who was susceptible to covid. That seems like a fair point to me.

    Thanks for the support! :smile: What I am actually saying is that existing blood tests can easily tell us which vitamins and minerals we're deficient in. Assuming that everyone admitted in to hospital with Covid is given a blood test (is this not standard medical procedure?), we could learn at a stroke, right now, which minerals and vitamins sufferers had significant deficiencies in (I would assume these are the same ones that those who get chronic diseases are also deficient in), and develop a long term plan to ensure that these are introduced or reintroduced in to our national diet.

    This would be a massively more scientific approach than the current 'Oh look, they tend to be old and fat' that seems to be the limit to anyone's analytical powers at the moment. Oldness, ethnicity, and fatness are meaningless. The first two you can't help, and the second you could well do yourself more harm than good if you tackled wrongly. Blood test data on the other hand is actionable.
  • MaxPBMaxPB Posts: 38,865

    The thing I find strange is that anyone tries with Putin. It is quite clear that he sees the world in terms of the sheep and the wolf.
    This episode was particularly humiliating, not only did the Russians quote his SputnikV comments in a video contradicting Navalny, he wasn't 5 minutes out the door and they were expelling EU diplomats....
    Sucking up to China wasn't enough, they also sucked up to Russia. I have to commend some of our remainers on here for seeing these moves for what they really are.
  • MalmesburyMalmesbury Posts: 50,357

    The thing I find strange is that anyone tries with Putin. It is quite clear that he sees the world in terms of the sheep and the wolf.
    This episode was particularly humiliating, not only did the Russians quote his SputnikV comments in a video contradicting Navalny, he wasn't 5 minutes out the door and they were expelling EU diplomats....
    Putin, I think, saw the EU speaking out on Navalny as then (the EU) speaking out of turn. To him, the EU/Germans should have the role of supplicants for Russian gas.

    So he was slapping down impudence.
  • AlistairAlistair Posts: 23,670
    edited February 2021

    Alistair said:

    Alistair said:

    Floater said:
    Agent P struggling with figures again.

    1 million doses hadn't even been delivered to Scotland by the end of January.
    What was delivered is irrelevant. The vaccines are held centrally and then ordered up as needed by the rollout teams in each nation. If those vaccines were not available to be ordered by Scotland, of course that's a good reason to miss the target. If they were, the fact that they were 'sitting in a warehouse in England' just means the rollout in Scotland was slower than promised as Agent P suggests.
    So you are saying Scotland could order the UK's entire stock of vaccine at the drop of a hat?
    Not at all, but the Scotland rollout team could have ordered up Scotland's full allocation over this time. We can surmise what that might have been by looking at the fastest vaccinating nation (don't know who it was by Feb 1) and seeing how many they did. Scotland's allocation would not have been less than 9% of that.
    If Scotland had matched England (the best vaccinating nation) to Jan 31st then Scotland (using a crude whole population ratio, I don't known what the proportion of vaccine eligible population in the 2 countries are) would have done 787k vaccinations.

    So well short of a million.

    Edit: I am extremely relieved that Scotland appears to have picked up the pace significantly this last week.
  • FairlieredFairliered Posts: 4,939

    Floater said:
    Who is this Agent P? He comes across as a complete wanker. His tweets are really irritating a la Dave Keating.
    He is a complete wanker. That’s why Carlotta retweets him.
  • Luckyguy1983Luckyguy1983 Posts: 28,477
    IshmaelZ said:

    kinabalu said:

    If we can reduce the lethality of Covid to that of a bad flu, we are fine. The vulnerable can be offered a vaccine yearly.

    Yep. But I'd say a wider vaccination than that.
    What is ludicrous to me is that a simple blood test would show that most of us are significantly deficient in key minerals and vitamins vs. internationally agreed (by Doctors) norms. This makes us vulnerable to infectious disease (as well as chronic disease, which increases year on year) - but there's no discussion about this in official circles. Instead of increasing our rubustness, academics and policy makers think a future as mask-wearing weaklings that need constant jabbing is an acceptable notion. I am not a 'Covid-denier', but it must be springboard to better health for everyone, not a trap door to mass medical dependency.
    Where is your evidence for that? Here

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060686/#!po=0.746269

    is a survey from 2018 showing that almost everybody is getting more than enough of almost everything. And - this is the best bit - 22% of their sample were taking supplements but they ignored those and just looked at what people are getting from their diet. Nutrition is great, but it doesn't "boost your immune system" and it is nothing to do with protecting yourself from viruses - masks and vaccines do that. The one exception is vitamin D and "official circles" are very far from silent about that.
    'Intake' in this context is not meaningful. It is the presence of these minerals in the body in sufficient quantities, as shown by a blood test, that is the only valid test - if those aren't present, then clearly we're either not 'intaking' these vitamins and minerals, or they are not sufficiently bioavailable in the foods and drinks we are getting them in. I could eat a packet of chalk, but that doesn't mean my body has actually absorbed and been able to make use of that calcium.
  • IshmaelZIshmaelZ Posts: 21,830

    Carnyx said:

    kinabalu said:

    If we can reduce the lethality of Covid to that of a bad flu, we are fine. The vulnerable can be offered a vaccine yearly.

    Yep. But I'd say a wider vaccination than that.
    What is ludicrous to me is that a simple blood test would show that most of us are significantly deficient in key minerals and vitamins vs. internationally agreed (by Doctors) norms. This makes us vulnerable to infectious disease (as well as chronic disease, which increases year on year) - but there's no discussion about this in official circles. Instead of increasing our rubustness, academics and policy makers think a future as mask-wearing weaklings that need constant jabbing is an acceptable notion. I am not a 'Covid-denier', but it must be springboard to better health for everyone, not a trap door to mass medical dependency.
    I must admit this business has got me taking vitD tablets (at the moderate rate generally recommended), being a Scot in the twilit winter, despite eating more than my fair share of mackerel, salmon, eggs and milk.
    "mask-wearing weaklings that need constant jabbing"

    Hmmmm

    Well, some people might think that. Or they might think that modern medicine and precautions beats Social Darwinism.

    All these weaklings, insisting on drains and potable water, anesthetics for their operations, antibiotics when they get a perfectly normal case of gangrene......
    That's a ludicrous straw man argument. I think we should make use of every wonderful benefit that building on the experience of our forebears can provide. These do not include (as a long term vision) standing two meters apart from everyone, covering the face, and being dependent on ever-changing vaccines merely to live.

    If you're such a fan of modern medicine, what could be more scientific than highlighting (using science) serious nutritional deficiencies and trying to do something about them? It is considerably more scientific an approach than telling people to 'lose weight'. The carrying of energy as fat is not, in and of itself even a disease.
    But the medical profession continues to peddle the myth that being overweight vastly increases the risk of diabetes, heart disease and cancer.
  • Floater said:
    Who is this Agent P? He comes across as a complete wanker. His tweets are really irritating a la Dave Keating.
    He is a complete wanker. That’s why Carlotta retweets him.
    I was under the impression he was a she, but let’s not get into the gender thing..
  • Luckyguy1983Luckyguy1983 Posts: 28,477
    Alistair said:

    Alistair said:

    Alistair said:

    Floater said:
    Agent P struggling with figures again.

    1 million doses hadn't even been delivered to Scotland by the end of January.
    What was delivered is irrelevant. The vaccines are held centrally and then ordered up as needed by the rollout teams in each nation. If those vaccines were not available to be ordered by Scotland, of course that's a good reason to miss the target. If they were, the fact that they were 'sitting in a warehouse in England' just means the rollout in Scotland was slower than promised as Agent P suggests.
    So you are saying Scotland could order the UK's entire stock of vaccine at the drop of a hat?
    Not at all, but the Scotland rollout team could have ordered up Scotland's full allocation over this time. We can surmise what that might have been by looking at the fastest vaccinating nation (don't know who it was by Feb 1) and seeing how many they did. Scotland's allocation would not have been less than 9% of that.
    If Scotland had matched England (the best vaccinating nation) to Jan 31st then Scotland (using a crude whole population ratio, I don't known what the proportion of vaccine eligible population in the 2 countries are) would have done 787k vaccinations.

    So well short of a million.

    Edit: I am extremely relieved that Scotland appears to have picked up the pace significantly this last week.
    Me too - it is a great effort by all those concerned in Scotland. I would now like any of the nations to kick it up yet another notch and make the rest look bad so they speed it up.

    I am sure your numbers are good, though remember it's the number on the morning of Feb 1 that we're looking at, to include Jan 31s vaccinations. It still looks like it would be short of a million, though that is predicated on England performing at capacity. We will never know how much headroom there actually was.
  • IshmaelZIshmaelZ Posts: 21,830

    IshmaelZ said:

    kinabalu said:

    If we can reduce the lethality of Covid to that of a bad flu, we are fine. The vulnerable can be offered a vaccine yearly.

    Yep. But I'd say a wider vaccination than that.
    What is ludicrous to me is that a simple blood test would show that most of us are significantly deficient in key minerals and vitamins vs. internationally agreed (by Doctors) norms. This makes us vulnerable to infectious disease (as well as chronic disease, which increases year on year) - but there's no discussion about this in official circles. Instead of increasing our rubustness, academics and policy makers think a future as mask-wearing weaklings that need constant jabbing is an acceptable notion. I am not a 'Covid-denier', but it must be springboard to better health for everyone, not a trap door to mass medical dependency.
    Where is your evidence for that? Here

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060686/#!po=0.746269

    is a survey from 2018 showing that almost everybody is getting more than enough of almost everything. And - this is the best bit - 22% of their sample were taking supplements but they ignored those and just looked at what people are getting from their diet. Nutrition is great, but it doesn't "boost your immune system" and it is nothing to do with protecting yourself from viruses - masks and vaccines do that. The one exception is vitamin D and "official circles" are very far from silent about that.
    'Intake' in this context is not meaningful. It is the presence of these minerals in the body in sufficient quantities, as shown by a blood test, that is the only valid test - if those aren't present, then clearly we're either not 'intaking' these vitamins and minerals, or they are not sufficiently bioavailable in the foods and drinks we are getting them in. I could eat a packet of chalk, but that doesn't mean my body has actually absorbed and been able to make use of that calcium.
    Absolute hokum. Why do you think there are such things as universally recognised recommended daily intakes if intake doesn't usefully correlate with bioavailability? Do you think you have spotted an obvious loophole that the entire worldwide medical profession has overlooked?
  • Luckyguy1983Luckyguy1983 Posts: 28,477
    IshmaelZ said:

    Carnyx said:

    kinabalu said:

    If we can reduce the lethality of Covid to that of a bad flu, we are fine. The vulnerable can be offered a vaccine yearly.

    Yep. But I'd say a wider vaccination than that.
    What is ludicrous to me is that a simple blood test would show that most of us are significantly deficient in key minerals and vitamins vs. internationally agreed (by Doctors) norms. This makes us vulnerable to infectious disease (as well as chronic disease, which increases year on year) - but there's no discussion about this in official circles. Instead of increasing our rubustness, academics and policy makers think a future as mask-wearing weaklings that need constant jabbing is an acceptable notion. I am not a 'Covid-denier', but it must be springboard to better health for everyone, not a trap door to mass medical dependency.
    I must admit this business has got me taking vitD tablets (at the moderate rate generally recommended), being a Scot in the twilit winter, despite eating more than my fair share of mackerel, salmon, eggs and milk.
    "mask-wearing weaklings that need constant jabbing"

    Hmmmm

    Well, some people might think that. Or they might think that modern medicine and precautions beats Social Darwinism.

    All these weaklings, insisting on drains and potable water, anesthetics for their operations, antibiotics when they get a perfectly normal case of gangrene......
    That's a ludicrous straw man argument. I think we should make use of every wonderful benefit that building on the experience of our forebears can provide. These do not include (as a long term vision) standing two meters apart from everyone, covering the face, and being dependent on ever-changing vaccines merely to live.

    If you're such a fan of modern medicine, what could be more scientific than highlighting (using science) serious nutritional deficiencies and trying to do something about them? It is considerably more scientific an approach than telling people to 'lose weight'. The carrying of energy as fat is not, in and of itself even a disease.
    But the medical profession continues to peddle the myth that being overweight vastly increases the risk of diabetes, heart disease and cancer.
    The correlation between being overweight and these diseases is undeniable, not a myth, but being overweight is a symptom, not a disease. The ability to carry energy (and toxins) as fat is a valuable function of the body - we'd be pretty buggered without it.
  • IshmaelZIshmaelZ Posts: 21,830

    Floater said:
    Who is this Agent P? He comes across as a complete wanker. His tweets are really irritating a la Dave Keating.
    He is a complete wanker. That’s why Carlotta retweets him.
    I was under the impression he was a she, but let’s not get into the gender thing..
    He is a he. The name is from

    https://en.wikipedia.org/wiki/Dinner_at_Eight_(1933_film)
  • FairlieredFairliered Posts: 4,939

    Floater said:
    Who is this Agent P? He comes across as a complete wanker. His tweets are really irritating a la Dave Keating.
    He is a complete wanker. That’s why Carlotta retweets him.
    I was under the impression he was a she, but let’s not get into the gender thing..
    Do we know that Carlotta isn’t Agent P? Have they ever been seen in the same room together?
  • PulpstarPulpstar Posts: 78,204
    IshmaelZ said:


    But the medical profession continues to peddle the myth that being overweight vastly increases the risk of diabetes, heart disease and cancer.

    That's errm... not a "myth"
  • FoxyFoxy Posts: 48,710
    IshmaelZ said:

    Carnyx said:

    kinabalu said:

    If we can reduce the lethality of Covid to that of a bad flu, we are fine. The vulnerable can be offered a vaccine yearly.

    Yep. But I'd say a wider vaccination than that.
    What is ludicrous to me is that a simple blood test would show that most of us are significantly deficient in key minerals and vitamins vs. internationally agreed (by Doctors) norms. This makes us vulnerable to infectious disease (as well as chronic disease, which increases year on year) - but there's no discussion about this in official circles. Instead of increasing our rubustness, academics and policy makers think a future as mask-wearing weaklings that need constant jabbing is an acceptable notion. I am not a 'Covid-denier', but it must be springboard to better health for everyone, not a trap door to mass medical dependency.
    I must admit this business has got me taking vitD tablets (at the moderate rate generally recommended), being a Scot in the twilit winter, despite eating more than my fair share of mackerel, salmon, eggs and milk.
    "mask-wearing weaklings that need constant jabbing"

    Hmmmm

    Well, some people might think that. Or they might think that modern medicine and precautions beats Social Darwinism.

    All these weaklings, insisting on drains and potable water, anesthetics for their operations, antibiotics when they get a perfectly normal case of gangrene......
    That's a ludicrous straw man argument. I think we should make use of every wonderful benefit that building on the experience of our forebears can provide. These do not include (as a long term vision) standing two meters apart from everyone, covering the face, and being dependent on ever-changing vaccines merely to live.

    If you're such a fan of modern medicine, what could be more scientific than highlighting (using science) serious nutritional deficiencies and trying to do something about them? It is considerably more scientific an approach than telling people to 'lose weight'. The carrying of energy as fat is not, in and of itself even a disease.
    But the medical profession continues to peddle the myth that being overweight vastly increases the risk of diabetes, heart disease and cancer.
    What magnitude of effect would you describe as "vast"?

    I note that you use the term overweight, is that as defined as a BMI of 25-30? Or of 25 upwards? Or do you work to a non standard definition of "overweight"?
  • Luckyguy1983Luckyguy1983 Posts: 28,477
    IshmaelZ said:

    IshmaelZ said:

    kinabalu said:

    If we can reduce the lethality of Covid to that of a bad flu, we are fine. The vulnerable can be offered a vaccine yearly.

    Yep. But I'd say a wider vaccination than that.
    What is ludicrous to me is that a simple blood test would show that most of us are significantly deficient in key minerals and vitamins vs. internationally agreed (by Doctors) norms. This makes us vulnerable to infectious disease (as well as chronic disease, which increases year on year) - but there's no discussion about this in official circles. Instead of increasing our rubustness, academics and policy makers think a future as mask-wearing weaklings that need constant jabbing is an acceptable notion. I am not a 'Covid-denier', but it must be springboard to better health for everyone, not a trap door to mass medical dependency.
    Where is your evidence for that? Here

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060686/#!po=0.746269

    is a survey from 2018 showing that almost everybody is getting more than enough of almost everything. And - this is the best bit - 22% of their sample were taking supplements but they ignored those and just looked at what people are getting from their diet. Nutrition is great, but it doesn't "boost your immune system" and it is nothing to do with protecting yourself from viruses - masks and vaccines do that. The one exception is vitamin D and "official circles" are very far from silent about that.
    'Intake' in this context is not meaningful. It is the presence of these minerals in the body in sufficient quantities, as shown by a blood test, that is the only valid test - if those aren't present, then clearly we're either not 'intaking' these vitamins and minerals, or they are not sufficiently bioavailable in the foods and drinks we are getting them in. I could eat a packet of chalk, but that doesn't mean my body has actually absorbed and been able to make use of that calcium.
    Absolute hokum. Why do you think there are such things as universally recognised recommended daily intakes if intake doesn't usefully correlate with bioavailability? Do you think you have spotted an obvious loophole that the entire worldwide medical profession has overlooked?
    Of course the entire medical profession hasn't ignored it. Most are not well versed in it, but it is universally accepted (except by you it seems). You've never heard of a fat soluble vitamin? Eat it with fat, it absorbs, without it, it won't. The whole world of nutrition is like that. You are arguing that we can measure the structural integrity of buildings by how much cement and brickwork were used. I say again, as far as I know, the severely ill receive blood tests in hospital as a matter of course. So why wouldn't you look at this actual data, rather than survey them as to what they had for lunch?
  • IshmaelZIshmaelZ Posts: 21,830
    Pulpstar said:

    IshmaelZ said:


    But the medical profession continues to peddle the myth that being overweight vastly increases the risk of diabetes, heart disease and cancer.

    That's errm... not a "myth"
    You too are in the pay of Big Pharma.
  • MalmesburyMalmesbury Posts: 50,357
    Pulpstar said:

    IshmaelZ said:


    But the medical profession continues to peddle the myth that being overweight vastly increases the risk of diabetes, heart disease and cancer.

    That's errm... not a "myth"
    Scientific studies that prove things that upset people are invalid.

    Didn't you get the memo?
  • sarissasarissa Posts: 1,993

    ydoethur said:

    ydoethur said:

    Andy_JS said:

    Bloody black people coming over here and taking over our gospel singing

    https://twitter.com/GreensladeR/status/1358469502908907520?s=20

    Gospel singing originated in the Outer Hebrides.
    Stor? No way!
    Barra-load of bollocks......
    Stop Harrising people.
    Or Islay tell on ya!
    Oh, ban them and be done with it. It’s Morar less the same in the end.
    This is a Rhum thread. In fact, it’s getting quite mucky. Anyway, I canna stay, the eigg man’s at the door.
    The Skye's the limit!
    After Mull-ing it over, Arran oot of things tae add....
  • PulpstarPulpstar Posts: 78,204
    IshmaelZ said:

    Pulpstar said:

    IshmaelZ said:


    But the medical profession continues to peddle the myth that being overweight vastly increases the risk of diabetes, heart disease and cancer.

    That's errm... not a "myth"
    You too are in the pay of Big Pharma.
    Not really, unless you're counting some very modest Glaxo dividends.
  • IshmaelZIshmaelZ Posts: 21,830
    Pulpstar said:

    IshmaelZ said:

    Pulpstar said:

    IshmaelZ said:


    But the medical profession continues to peddle the myth that being overweight vastly increases the risk of diabetes, heart disease and cancer.

    That's errm... not a "myth"
    You too are in the pay of Big Pharma.
    Not really, unless you're counting some very modest Glaxo dividends.
    Um, I was joking. Both times.
  • Luckyguy1983Luckyguy1983 Posts: 28,477

    Carnyx said:

    kinabalu said:

    If we can reduce the lethality of Covid to that of a bad flu, we are fine. The vulnerable can be offered a vaccine yearly.

    Yep. But I'd say a wider vaccination than that.
    What is ludicrous to me is that a simple blood test would show that most of us are significantly deficient in key minerals and vitamins vs. internationally agreed (by Doctors) norms. This makes us vulnerable to infectious disease (as well as chronic disease, which increases year on year) - but there's no discussion about this in official circles. Instead of increasing our rubustness, academics and policy makers think a future as mask-wearing weaklings that need constant jabbing is an acceptable notion. I am not a 'Covid-denier', but it must be springboard to better health for everyone, not a trap door to mass medical dependency.
    I must admit this business has got me taking vitD tablets (at the moderate rate generally recommended), being a Scot in the twilit winter, despite eating more than my fair share of mackerel, salmon, eggs and milk.
    "mask-wearing weaklings that need constant jabbing"

    Hmmmm

    Well, some people might think that. Or they might think that modern medicine and precautions beats Social Darwinism.

    All these weaklings, insisting on drains and potable water, anesthetics for their operations, antibiotics when they get a perfectly normal case of gangrene......
    That's a ludicrous straw man argument. I think we should make use of every wonderful benefit that building on the experience of our forebears can provide. These do not include (as a long term vision) standing two meters apart from everyone, covering the face, and being dependent on ever-changing vaccines merely to live.

    If you're such a fan of modern medicine, what could be more scientific than highlighting (using science) serious nutritional deficiencies and trying to do something about them? It is considerably more scientific an approach than telling people to 'lose weight'. The carrying of energy as fat is not, in and of itself even a disease.
    It's not about "merely to live" - so that an *increasing* number of people continue to live. That whole progress thing.

    The claim that vitamin D deficiency increases COVID susceptibility hasn't been proven in any study.
    That's a totally circular argument - I am asking for it to BE studied - not even with precise relevance to Vitamin D, but to all minerals and vitamins, using the vast resource of blood test data that there undoubtedly is. If significant deficiencies are common, that's at least a good pointer - certainly a better one than 'don't be fat, don't get old'.
  • IshmaelZIshmaelZ Posts: 21,830

    IshmaelZ said:

    IshmaelZ said:

    kinabalu said:

    If we can reduce the lethality of Covid to that of a bad flu, we are fine. The vulnerable can be offered a vaccine yearly.

    Yep. But I'd say a wider vaccination than that.
    What is ludicrous to me is that a simple blood test would show that most of us are significantly deficient in key minerals and vitamins vs. internationally agreed (by Doctors) norms. This makes us vulnerable to infectious disease (as well as chronic disease, which increases year on year) - but there's no discussion about this in official circles. Instead of increasing our rubustness, academics and policy makers think a future as mask-wearing weaklings that need constant jabbing is an acceptable notion. I am not a 'Covid-denier', but it must be springboard to better health for everyone, not a trap door to mass medical dependency.
    Where is your evidence for that? Here

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060686/#!po=0.746269

    is a survey from 2018 showing that almost everybody is getting more than enough of almost everything. And - this is the best bit - 22% of their sample were taking supplements but they ignored those and just looked at what people are getting from their diet. Nutrition is great, but it doesn't "boost your immune system" and it is nothing to do with protecting yourself from viruses - masks and vaccines do that. The one exception is vitamin D and "official circles" are very far from silent about that.
    'Intake' in this context is not meaningful. It is the presence of these minerals in the body in sufficient quantities, as shown by a blood test, that is the only valid test - if those aren't present, then clearly we're either not 'intaking' these vitamins and minerals, or they are not sufficiently bioavailable in the foods and drinks we are getting them in. I could eat a packet of chalk, but that doesn't mean my body has actually absorbed and been able to make use of that calcium.
    Absolute hokum. Why do you think there are such things as universally recognised recommended daily intakes if intake doesn't usefully correlate with bioavailability? Do you think you have spotted an obvious loophole that the entire worldwide medical profession has overlooked?
    Of course the entire medical profession hasn't ignored it. Most are not well versed in it, but it is universally accepted (except by you it seems). You've never heard of a fat soluble vitamin? Eat it with fat, it absorbs, without it, it won't. The whole world of nutrition is like that. You are arguing that we can measure the structural integrity of buildings by how much cement and brickwork were used. I say again, as far as I know, the severely ill receive blood tests in hospital as a matter of course. So why wouldn't you look at this actual data, rather than survey them as to what they had for lunch?
    OK so you are ahead of most of the medical profession on this. What are the odds of that?

    Best we leave it there, because I don't want to have my fear confirmed that you are the kind of person who recommends cancer patients should drink more organic smoothies.
  • Luckyguy1983Luckyguy1983 Posts: 28,477

    Pulpstar said:

    IshmaelZ said:


    But the medical profession continues to peddle the myth that being overweight vastly increases the risk of diabetes, heart disease and cancer.

    That's errm... not a "myth"
    Scientific studies that prove things that upset people are invalid.

    Didn't you get the memo?
    On the contrary, I am the one ASKING for scientific studies. We have levels of vitamins and minerals that are deemed BY SCIENTISTS to be optimal in the body. We (presumably) have a vast repository of blood test data from Covid patients. Should we not look at this vast data resource to confirm whether there is significant correlation between deficiencies in whatever minerals and vitamins that are present, with severity of Covid. I don't see how this could be more scientific if it tried.
  • BenpointerBenpointer Posts: 34,673

    Carnyx said:

    kinabalu said:

    If we can reduce the lethality of Covid to that of a bad flu, we are fine. The vulnerable can be offered a vaccine yearly.

    Yep. But I'd say a wider vaccination than that.
    What is ludicrous to me is that a simple blood test would show that most of us are significantly deficient in key minerals and vitamins vs. internationally agreed (by Doctors) norms. This makes us vulnerable to infectious disease (as well as chronic disease, which increases year on year) - but there's no discussion about this in official circles. Instead of increasing our rubustness, academics and policy makers think a future as mask-wearing weaklings that need constant jabbing is an acceptable notion. I am not a 'Covid-denier', but it must be springboard to better health for everyone, not a trap door to mass medical dependency.
    I must admit this business has got me taking vitD tablets (at the moderate rate generally recommended), being a Scot in the twilit winter, despite eating more than my fair share of mackerel, salmon, eggs and milk.
    "mask-wearing weaklings that need constant jabbing"

    Hmmmm

    Well, some people might think that. Or they might think that modern medicine and precautions beats Social Darwinism.

    All these weaklings, insisting on drains and potable water, anesthetics for their operations, antibiotics when they get a perfectly normal case of gangrene......
    That's a ludicrous straw man argument. I think we should make use of every wonderful benefit that building on the experience of our forebears can provide. These do not include (as a long term vision) standing two meters apart from everyone, covering the face, and being dependent on ever-changing vaccines merely to live.

    If you're such a fan of modern medicine, what could be more scientific than highlighting (using science) serious nutritional deficiencies and trying to do something about them? It is considerably more scientific an approach than telling people to 'lose weight'. The carrying of energy as fat is not, in and of itself even a disease.
    It's not about "merely to live" - so that an *increasing* number of people continue to live. That whole progress thing.

    The claim that vitamin D deficiency increases COVID susceptibility hasn't been proven in any study.
    That's a totally circular argument - I am asking for it to BE studied - not even with precise relevance to Vitamin D, but to all minerals and vitamins, using the vast resource of blood test data that there undoubtedly is. If significant deficiencies are common, that's at least a good pointer - certainly a better one than 'don't be fat, don't get old'.
    Where do you get your diet fad hokum information from @Luckyguy1983?

    If you want a good book on diet and nutrition try Tim Spector's The Diet Myth. Spector btw is not entirely struck on the vitamin supplement fashion:

    https://theconversation.com/the-sun-goes-down-on-vitamin-d-why-i-changed-my-mind-about-this-celebrated-supplement-52725
  • Luckyguy1983Luckyguy1983 Posts: 28,477
    IshmaelZ said:

    IshmaelZ said:

    IshmaelZ said:

    kinabalu said:

    If we can reduce the lethality of Covid to that of a bad flu, we are fine. The vulnerable can be offered a vaccine yearly.

    Yep. But I'd say a wider vaccination than that.
    What is ludicrous to me is that a simple blood test would show that most of us are significantly deficient in key minerals and vitamins vs. internationally agreed (by Doctors) norms. This makes us vulnerable to infectious disease (as well as chronic disease, which increases year on year) - but there's no discussion about this in official circles. Instead of increasing our rubustness, academics and policy makers think a future as mask-wearing weaklings that need constant jabbing is an acceptable notion. I am not a 'Covid-denier', but it must be springboard to better health for everyone, not a trap door to mass medical dependency.
    Where is your evidence for that? Here

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060686/#!po=0.746269

    is a survey from 2018 showing that almost everybody is getting more than enough of almost everything. And - this is the best bit - 22% of their sample were taking supplements but they ignored those and just looked at what people are getting from their diet. Nutrition is great, but it doesn't "boost your immune system" and it is nothing to do with protecting yourself from viruses - masks and vaccines do that. The one exception is vitamin D and "official circles" are very far from silent about that.
    'Intake' in this context is not meaningful. It is the presence of these minerals in the body in sufficient quantities, as shown by a blood test, that is the only valid test - if those aren't present, then clearly we're either not 'intaking' these vitamins and minerals, or they are not sufficiently bioavailable in the foods and drinks we are getting them in. I could eat a packet of chalk, but that doesn't mean my body has actually absorbed and been able to make use of that calcium.
    Absolute hokum. Why do you think there are such things as universally recognised recommended daily intakes if intake doesn't usefully correlate with bioavailability? Do you think you have spotted an obvious loophole that the entire worldwide medical profession has overlooked?
    Of course the entire medical profession hasn't ignored it. Most are not well versed in it, but it is universally accepted (except by you it seems). You've never heard of a fat soluble vitamin? Eat it with fat, it absorbs, without it, it won't. The whole world of nutrition is like that. You are arguing that we can measure the structural integrity of buildings by how much cement and brickwork were used. I say again, as far as I know, the severely ill receive blood tests in hospital as a matter of course. So why wouldn't you look at this actual data, rather than survey them as to what they had for lunch?
    OK so you are ahead of most of the medical profession on this. What are the odds of that?

    Best we leave it there, because I don't want to have my fear confirmed that you are the kind of person who recommends cancer patients should drink more organic smoothies.
    No, I am pretty sure the medical profession is up to speed with the concept of bioavailability of vitamins and minerals - it seems to be just you that doesn't really get it.

    Accidentally however, you do raise a good point. Nutrition is a tiny part of the medical school curriculum - 'We're taught about 10 to 24 hours over five to six years in medical school on nutrition.' https://www.bbc.co.uk/news/amp/health-43504125

    Most people who are interested in any topic will spend longer than 24 hours over their years learning about it.
  • DougSealDougSeal Posts: 12,541
    The South African variant is indeed deeply worrying - but surely it is of comfort that cases and deaths there have been continuously declining for weeks now? Lockdown there was eased quite substantially last week and we shall see if that makes things worse again, but surely the fact that cases have been brought under control with relative ease in a country that’s a home grown mutant strain, huge wealth disparities and areas where social distancing is impossible must be positive?
  • BenpointerBenpointer Posts: 34,673
    edited February 2021
    IshmaelZ said:

    IshmaelZ said:

    IshmaelZ said:

    kinabalu said:

    If we can reduce the lethality of Covid to that of a bad flu, we are fine. The vulnerable can be offered a vaccine yearly.

    Yep. But I'd say a wider vaccination than that.
    What is ludicrous to me is that a simple blood test would show that most of us are significantly deficient in key minerals and vitamins vs. internationally agreed (by Doctors) norms. This makes us vulnerable to infectious disease (as well as chronic disease, which increases year on year) - but there's no discussion about this in official circles. Instead of increasing our rubustness, academics and policy makers think a future as mask-wearing weaklings that need constant jabbing is an acceptable notion. I am not a 'Covid-denier', but it must be springboard to better health for everyone, not a trap door to mass medical dependency.
    Where is your evidence for that? Here

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060686/#!po=0.746269

    is a survey from 2018 showing that almost everybody is getting more than enough of almost everything. And - this is the best bit - 22% of their sample were taking supplements but they ignored those and just looked at what people are getting from their diet. Nutrition is great, but it doesn't "boost your immune system" and it is nothing to do with protecting yourself from viruses - masks and vaccines do that. The one exception is vitamin D and "official circles" are very far from silent about that.
    'Intake' in this context is not meaningful. It is the presence of these minerals in the body in sufficient quantities, as shown by a blood test, that is the only valid test - if those aren't present, then clearly we're either not 'intaking' these vitamins and minerals, or they are not sufficiently bioavailable in the foods and drinks we are getting them in. I could eat a packet of chalk, but that doesn't mean my body has actually absorbed and been able to make use of that calcium.
    Absolute hokum. Why do you think there are such things as universally recognised recommended daily intakes if intake doesn't usefully correlate with bioavailability? Do you think you have spotted an obvious loophole that the entire worldwide medical profession has overlooked?
    Of course the entire medical profession hasn't ignored it. Most are not well versed in it, but it is universally accepted (except by you it seems). You've never heard of a fat soluble vitamin? Eat it with fat, it absorbs, without it, it won't. The whole world of nutrition is like that. You are arguing that we can measure the structural integrity of buildings by how much cement and brickwork were used. I say again, as far as I know, the severely ill receive blood tests in hospital as a matter of course. So why wouldn't you look at this actual data, rather than survey them as to what they had for lunch?
    OK so you are ahead of most of the medical profession on this. What are the odds of that?

    Best we leave it there, because I don't want to have my fear confirmed that you are the kind of person who recommends cancer patients should drink more organic smoothies.
    The cruelest cult 'treatment' for cancer (and I am sure @Luckyguy1983 has no truck with this one) is surely the coffee enema fad - encourage ill and vulnerable people to undergo uncomfortable embarrassing procedures for zero benefit.
  • Pro_RataPro_Rata Posts: 5,288
    sarissa said:

    ydoethur said:

    ydoethur said:

    Andy_JS said:

    Bloody black people coming over here and taking over our gospel singing

    https://twitter.com/GreensladeR/status/1358469502908907520?s=20

    Gospel singing originated in the Outer Hebrides.
    Stor? No way!
    Barra-load of bollocks......
    Stop Harrising people.
    Or Islay tell on ya!
    Oh, ban them and be done with it. It’s Morar less the same in the end.
    This is a Rhum thread. In fact, it’s getting quite mucky. Anyway, I canna stay, the eigg man’s at the door.
    The Skye's the limit!
    After Mull-ing it over, Arran oot of things tae add....
    The Jura's still Outer on that one, but Iona few ticks it'll be Inner.
  • Luckyguy1983Luckyguy1983 Posts: 28,477

    Carnyx said:

    kinabalu said:

    If we can reduce the lethality of Covid to that of a bad flu, we are fine. The vulnerable can be offered a vaccine yearly.

    Yep. But I'd say a wider vaccination than that.
    What is ludicrous to me is that a simple blood test would show that most of us are significantly deficient in key minerals and vitamins vs. internationally agreed (by Doctors) norms. This makes us vulnerable to infectious disease (as well as chronic disease, which increases year on year) - but there's no discussion about this in official circles. Instead of increasing our rubustness, academics and policy makers think a future as mask-wearing weaklings that need constant jabbing is an acceptable notion. I am not a 'Covid-denier', but it must be springboard to better health for everyone, not a trap door to mass medical dependency.
    I must admit this business has got me taking vitD tablets (at the moderate rate generally recommended), being a Scot in the twilit winter, despite eating more than my fair share of mackerel, salmon, eggs and milk.
    "mask-wearing weaklings that need constant jabbing"

    Hmmmm

    Well, some people might think that. Or they might think that modern medicine and precautions beats Social Darwinism.

    All these weaklings, insisting on drains and potable water, anesthetics for their operations, antibiotics when they get a perfectly normal case of gangrene......
    That's a ludicrous straw man argument. I think we should make use of every wonderful benefit that building on the experience of our forebears can provide. These do not include (as a long term vision) standing two meters apart from everyone, covering the face, and being dependent on ever-changing vaccines merely to live.

    If you're such a fan of modern medicine, what could be more scientific than highlighting (using science) serious nutritional deficiencies and trying to do something about them? It is considerably more scientific an approach than telling people to 'lose weight'. The carrying of energy as fat is not, in and of itself even a disease.
    It's not about "merely to live" - so that an *increasing* number of people continue to live. That whole progress thing.

    The claim that vitamin D deficiency increases COVID susceptibility hasn't been proven in any study.
    That's a totally circular argument - I am asking for it to BE studied - not even with precise relevance to Vitamin D, but to all minerals and vitamins, using the vast resource of blood test data that there undoubtedly is. If significant deficiencies are common, that's at least a good pointer - certainly a better one than 'don't be fat, don't get old'.
    Where do you get your diet fad hokum information from @Luckyguy1983?

    If you want a good book on diet and nutrition try Tim Spector's The Diet Myth. Spector btw is not entirely struck on the vitamin supplement fashion:

    https://theconversation.com/the-sun-goes-down-on-vitamin-d-why-i-changed-my-mind-about-this-celebrated-supplement-52725
    What diet fad hokum do you actually think I have spread in this discussion? If you have a blood test YOUR DOCTOR will tell you that you are deficient in certain minerals and vitamins. I merely suggest we should examine this data with reference to Covid. I am puzzled as to why this is in any way a controversial concept.

    As for Vit D supplements, I think the general consensus is that they don't work that well, and I wouldn't disagree.
  • Luckyguy1983Luckyguy1983 Posts: 28,477

    IshmaelZ said:

    IshmaelZ said:

    IshmaelZ said:

    kinabalu said:

    If we can reduce the lethality of Covid to that of a bad flu, we are fine. The vulnerable can be offered a vaccine yearly.

    Yep. But I'd say a wider vaccination than that.
    What is ludicrous to me is that a simple blood test would show that most of us are significantly deficient in key minerals and vitamins vs. internationally agreed (by Doctors) norms. This makes us vulnerable to infectious disease (as well as chronic disease, which increases year on year) - but there's no discussion about this in official circles. Instead of increasing our rubustness, academics and policy makers think a future as mask-wearing weaklings that need constant jabbing is an acceptable notion. I am not a 'Covid-denier', but it must be springboard to better health for everyone, not a trap door to mass medical dependency.
    Where is your evidence for that? Here

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060686/#!po=0.746269

    is a survey from 2018 showing that almost everybody is getting more than enough of almost everything. And - this is the best bit - 22% of their sample were taking supplements but they ignored those and just looked at what people are getting from their diet. Nutrition is great, but it doesn't "boost your immune system" and it is nothing to do with protecting yourself from viruses - masks and vaccines do that. The one exception is vitamin D and "official circles" are very far from silent about that.
    'Intake' in this context is not meaningful. It is the presence of these minerals in the body in sufficient quantities, as shown by a blood test, that is the only valid test - if those aren't present, then clearly we're either not 'intaking' these vitamins and minerals, or they are not sufficiently bioavailable in the foods and drinks we are getting them in. I could eat a packet of chalk, but that doesn't mean my body has actually absorbed and been able to make use of that calcium.
    Absolute hokum. Why do you think there are such things as universally recognised recommended daily intakes if intake doesn't usefully correlate with bioavailability? Do you think you have spotted an obvious loophole that the entire worldwide medical profession has overlooked?
    Of course the entire medical profession hasn't ignored it. Most are not well versed in it, but it is universally accepted (except by you it seems). You've never heard of a fat soluble vitamin? Eat it with fat, it absorbs, without it, it won't. The whole world of nutrition is like that. You are arguing that we can measure the structural integrity of buildings by how much cement and brickwork were used. I say again, as far as I know, the severely ill receive blood tests in hospital as a matter of course. So why wouldn't you look at this actual data, rather than survey them as to what they had for lunch?
    OK so you are ahead of most of the medical profession on this. What are the odds of that?

    Best we leave it there, because I don't want to have my fear confirmed that you are the kind of person who recommends cancer patients should drink more organic smoothies.
    The cruelest cult 'treatment' for cancer (and I am sure @Luckyguy1983 has no truck with this one) is surely the coffee enema fad - encourage ill and vulnerable people to undergo uncomfortable embarrassing procedures for zero benefit.
    I have no idea what that is meant to do, and I can't see any way that it could be efficacious, but I wouldn't dismiss anything before I at least know how it is 'meant' to work. It wouldn't be very scientific would it? I watched a programme about a man and his wife who were totally addicted to coffee enemas, so clearly not everybody finds it uncomfortable or embarrassing.
  • IshmaelZIshmaelZ Posts: 21,830

    IshmaelZ said:

    IshmaelZ said:

    IshmaelZ said:

    kinabalu said:

    If we can reduce the lethality of Covid to that of a bad flu, we are fine. The vulnerable can be offered a vaccine yearly.

    Yep. But I'd say a wider vaccination than that.
    What is ludicrous to me is that a simple blood test would show that most of us are significantly deficient in key minerals and vitamins vs. internationally agreed (by Doctors) norms. This makes us vulnerable to infectious disease (as well as chronic disease, which increases year on year) - but there's no discussion about this in official circles. Instead of increasing our rubustness, academics and policy makers think a future as mask-wearing weaklings that need constant jabbing is an acceptable notion. I am not a 'Covid-denier', but it must be springboard to better health for everyone, not a trap door to mass medical dependency.
    Where is your evidence for that? Here

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060686/#!po=0.746269

    is a survey from 2018 showing that almost everybody is getting more than enough of almost everything. And - this is the best bit - 22% of their sample were taking supplements but they ignored those and just looked at what people are getting from their diet. Nutrition is great, but it doesn't "boost your immune system" and it is nothing to do with protecting yourself from viruses - masks and vaccines do that. The one exception is vitamin D and "official circles" are very far from silent about that.
    'Intake' in this context is not meaningful. It is the presence of these minerals in the body in sufficient quantities, as shown by a blood test, that is the only valid test - if those aren't present, then clearly we're either not 'intaking' these vitamins and minerals, or they are not sufficiently bioavailable in the foods and drinks we are getting them in. I could eat a packet of chalk, but that doesn't mean my body has actually absorbed and been able to make use of that calcium.
    Absolute hokum. Why do you think there are such things as universally recognised recommended daily intakes if intake doesn't usefully correlate with bioavailability? Do you think you have spotted an obvious loophole that the entire worldwide medical profession has overlooked?
    Of course the entire medical profession hasn't ignored it. Most are not well versed in it, but it is universally accepted (except by you it seems). You've never heard of a fat soluble vitamin? Eat it with fat, it absorbs, without it, it won't. The whole world of nutrition is like that. You are arguing that we can measure the structural integrity of buildings by how much cement and brickwork were used. I say again, as far as I know, the severely ill receive blood tests in hospital as a matter of course. So why wouldn't you look at this actual data, rather than survey them as to what they had for lunch?
    OK so you are ahead of most of the medical profession on this. What are the odds of that?

    Best we leave it there, because I don't want to have my fear confirmed that you are the kind of person who recommends cancer patients should drink more organic smoothies.
    No, I am pretty sure the medical profession is up to speed with the concept of bioavailability of vitamins and minerals - it seems to be just you that doesn't really get it.

    Accidentally however, you do raise a good point. Nutrition is a tiny part of the medical school curriculum - 'We're taught about 10 to 24 hours over five to six years in medical school on nutrition.' https://www.bbc.co.uk/news/amp/health-43504125

    Most people who are interested in any topic will spend longer than 24 hours over their years learning about it.
    OK, so they are aware of the concept of bioavailability. What makes you think they do not take it into account when setting RDAs? How would you even have the concept of an RDA unless you were confident there was a strong, virtually invariant and well understood correlation between the two?

    And why do you think that those who go to medical school limit their research into nutrition to what they are taught at school? You have plainly spent more than 24 hours of your time over the years learning about it in your spare time. What makes you think they haven't?
  • Foxy said:

    Foxy said:

    31 years old. I wouldn't have expected hospitalisation or death in that group, so probably why couldn't be commented on.
    That study is underpowered. The vaccine efficacy confidence interval (against B.1.351) was -78.8% to +54.8%. It would be a mistake to read too much into it, at this point.

    The data on re-infection is a little bit more robust, though: if antibody presence from past infection confers immunity to B.1.351 then it can't be a huge amount. That's a more worrying finding. Good reason to try to keep this variant out of the UK, or suppress it hard.

    And yes, the study has nothing to say about serious illness. I wonder what they were thinking when they recruited for it. Underpowered medical trials are a real problem for science, and lead to bad policy.

    --AS

    Edit: and, to follow up on reinfection, the same finding happened in the Novavax trial. So I think that conclusion is becoming more firm.
    I understood it to be a further follow up of the original AZN trial in RSA (Cov005) reported in the Lancet in November. That had 2096 enrolled, with a 4 week interval and allowing for a bit of dropout leaving 1749 for this analysis.
    But to what end? Just to study the new SA variant? It's too small. And the cohort way too young. There's so little point in these tiny studies, they can't show anything much. They shouldn't be funded, in my opinion.

    --AS
  • IshmaelZIshmaelZ Posts: 21,830
    https://www.telegraph.co.uk/politics/2021/02/07/vaccines-minister-public-can-confident-oxford-jab-effective/

    "Ministers recognise that the disease will not be defeated through a single vaccine drive, but rather kept at bay through the delivery of a series of tweaked jabs to combat emerging variants."

    A major spin shift.
  • Luckyguy1983Luckyguy1983 Posts: 28,477
    edited February 2021
    IshmaelZ said:

    IshmaelZ said:

    IshmaelZ said:

    IshmaelZ said:

    kinabalu said:

    If we can reduce the lethality of Covid to that of a bad flu, we are fine. The vulnerable can be offered a vaccine yearly.

    Yep. But I'd say a wider vaccination than that.
    What is ludicrous to me is that a simple blood test would show that most of us are significantly deficient in key minerals and vitamins vs. internationally agreed (by Doctors) norms. This makes us vulnerable to infectious disease (as well as chronic disease, which increases year on year) - but there's no discussion about this in official circles. Instead of increasing our rubustness, academics and policy makers think a future as mask-wearing weaklings that need constant jabbing is an acceptable notion. I am not a 'Covid-denier', but it must be springboard to better health for everyone, not a trap door to mass medical dependency.
    Where is your evidence for that? Here

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060686/#!po=0.746269

    is a survey from 2018 showing that almost everybody is getting more than enough of almost everything. And - this is the best bit - 22% of their sample were taking supplements but they ignored those and just looked at what people are getting from their diet. Nutrition is great, but it doesn't "boost your immune system" and it is nothing to do with protecting yourself from viruses - masks and vaccines do that. The one exception is vitamin D and "official circles" are very far from silent about that.
    'Intake' in this context is not meaningful. It is the presence of these minerals in the body in sufficient quantities, as shown by a blood test, that is the only valid test - if those aren't present, then clearly we're either not 'intaking' these vitamins and minerals, or they are not sufficiently bioavailable in the foods and drinks we are getting them in. I could eat a packet of chalk, but that doesn't mean my body has actually absorbed and been able to make use of that calcium.
    Absolute hokum. Why do you think there are such things as universally recognised recommended daily intakes if intake doesn't usefully correlate with bioavailability? Do you think you have spotted an obvious loophole that the entire worldwide medical profession has overlooked?
    Of course the entire medical profession hasn't ignored it. Most are not well versed in it, but it is universally accepted (except by you it seems). You've never heard of a fat soluble vitamin? Eat it with fat, it absorbs, without it, it won't. The whole world of nutrition is like that. You are arguing that we can measure the structural integrity of buildings by how much cement and brickwork were used. I say again, as far as I know, the severely ill receive blood tests in hospital as a matter of course. So why wouldn't you look at this actual data, rather than survey them as to what they had for lunch?
    OK so you are ahead of most of the medical profession on this. What are the odds of that?

    Best we leave it there, because I don't want to have my fear confirmed that you are the kind of person who recommends cancer patients should drink more organic smoothies.
    No, I am pretty sure the medical profession is up to speed with the concept of bioavailability of vitamins and minerals - it seems to be just you that doesn't really get it.

    Accidentally however, you do raise a good point. Nutrition is a tiny part of the medical school curriculum - 'We're taught about 10 to 24 hours over five to six years in medical school on nutrition.' https://www.bbc.co.uk/news/amp/health-43504125

    Most people who are interested in any topic will spend longer than 24 hours over their years learning about it.
    OK, so they are aware of the concept of bioavailability. What makes you think they do not take it into account when setting RDAs? How would you even have the concept of an RDA unless you were confident there was a strong, virtually invariant and well understood correlation between the two?

    And why do you think that those who go to medical school limit their research into nutrition to what they are taught at school? You have plainly spent more than 24 hours of your time over the years learning about it in your spare time. What makes you think they haven't?
    We have RDAs as a guide to how much of these vitamins and minerals we should be absorbing, not how much we should be chucking down the hatch. If you buy an expensive vitamin supplement, you will notice that the quantities shown on the side are not 100% RDA, because it will have been formulated knowing that certain vitamins and minerals have negative and positive relationships to each other, so (and this isn't a real example) the presence of magnesium might inhibit selenium uptake, so you actually need 300% RDA of selenium to compensate. A cheap supermarket supplement will just contain 100% of everything, which is one reason (among many) that it will do f-all. Another example is the complex relationship between calcium, magnesium, vitamin d and vitamin k. They use each other and you can't just chuck some of them at your body and expect it to work. That's why vitamins and minerals are best supplied by food, because they occur in food naturally in the right quantities and they are absorbable.
  • Andy_JSAndy_JS Posts: 32,588
    edited February 2021
    Still think these odds are baffling. An England win is more likely than a draw in my opinion.

    India 34
    England 2.26
    Draw 1.88

    https://www.betfair.com/exchange/plus/cricket/market/1.178000173
  • FoxyFoxy Posts: 48,710

    Foxy said:

    Foxy said:

    31 years old. I wouldn't have expected hospitalisation or death in that group, so probably why couldn't be commented on.
    That study is underpowered. The vaccine efficacy confidence interval (against B.1.351) was -78.8% to +54.8%. It would be a mistake to read too much into it, at this point.

    The data on re-infection is a little bit more robust, though: if antibody presence from past infection confers immunity to B.1.351 then it can't be a huge amount. That's a more worrying finding. Good reason to try to keep this variant out of the UK, or suppress it hard.

    And yes, the study has nothing to say about serious illness. I wonder what they were thinking when they recruited for it. Underpowered medical trials are a real problem for science, and lead to bad policy.

    --AS

    Edit: and, to follow up on reinfection, the same finding happened in the Novavax trial. So I think that conclusion is becoming more firm.
    I understood it to be a further follow up of the original AZN trial in RSA (Cov005) reported in the Lancet in November. That had 2096 enrolled, with a 4 week interval and allowing for a bit of dropout leaving 1749 for this analysis.
    But to what end? Just to study the new SA variant? It's too small. And the cohort way too young. There's so little point in these tiny studies, they can't show anything much. They shouldn't be funded, in my opinion.

    --AS
    The RSA trial was much smaller than the UK and Brazilian ones done by AZN, indeed it is barely touched on in the published Lancet paper.

    I agree it is underpowered, and presumably unethical to continue with a placebo arm
  • JonathanDJonathanD Posts: 2,400
    Scott_xP said:
    Ireland also appear to have decided not to use AZ for over 70s so no chance of dumping our stock on them.

    https://www.rte.ie/news/coronavirus/2021/0204/1194946-covid-vaccine/
  • Luckyguy1983Luckyguy1983 Posts: 28,477
    JonathanD said:

    Scott_xP said:
    Ireland also appear to have decided not to use AZ for over 70s so no chance of dumping our stock on them.

    https://www.rte.ie/news/coronavirus/2021/0204/1194946-covid-vaccine/
    I feel very sorry for Oxford, having deliberately not recruited the elderly for testing until they had checked safety on the younger cohorts. It really does seem no good deed goes unpunished sometimes!
  • JonathanD said:

    Scott_xP said:
    Ireland also appear to have decided not to use AZ for over 70s so no chance of dumping our stock on them.

    https://www.rte.ie/news/coronavirus/2021/0204/1194946-covid-vaccine/
    Why would we dump vaccine that is going to save lives

    Strange use of language
  • JonathanDJonathanD Posts: 2,400

    JonathanD said:

    Scott_xP said:
    Ireland also appear to have decided not to use AZ for over 70s so no chance of dumping our stock on them.

    https://www.rte.ie/news/coronavirus/2021/0204/1194946-covid-vaccine/
    I feel very sorry for Oxford, having deliberately not recruited the elderly for testing until they had checked safety on the younger cohorts. It really does seem no good deed goes unpunished sometimes!
    It does look a bit like UoOxford had too much influence on the delivery of this vaccine. Partnering with AZ rather than Merck may have guaranteed UK production but a company more familiar with vaccine drugs might have avoided the pitfalls that AZ appear to have fallen into and which Pfizer and Moderna navigated around.

    You are right though, that for a drug that is being distributed on a non-profit basis, they are attracting a huge amount of negative attention.
  • Attention, sports fans! Superbowl LV starts in just under one half hour.
  • pingping Posts: 3,805
    edited February 2021

    Attention, sports fans! Superbowl LV starts in just under one half hour.

    Any tips?

    Where’s @Tissue_Price when you need him? Iirc, NFL is his area of expertise. Probably has some lame excuse about representing the people, or something. Pft
  • fox327fox327 Posts: 370
    edited February 2021
    DougSeal said:

    The South African variant is indeed deeply worrying - but surely it is of comfort that cases and deaths there have been continuously declining for weeks now? Lockdown there was eased quite substantially last week and we shall see if that makes things worse again, but surely the fact that cases have been brought under control with relative ease in a country that’s a home grown mutant strain, huge wealth disparities and areas where social distancing is impossible must be positive?

    The cases have come down. Has it been actually been brought under control or has it merely burnt its way uncontained through most of the population, and then declined as very few people left alive are still susceptible? You might not think it is positive if it is the latter scenario that applies.

    The plague too declined in Italian villages in 1347 after 70% of the population had died.
  • Luckyguy1983Luckyguy1983 Posts: 28,477
    JonathanD said:

    JonathanD said:

    Scott_xP said:
    Ireland also appear to have decided not to use AZ for over 70s so no chance of dumping our stock on them.

    https://www.rte.ie/news/coronavirus/2021/0204/1194946-covid-vaccine/
    I feel very sorry for Oxford, having deliberately not recruited the elderly for testing until they had checked safety on the younger cohorts. It really does seem no good deed goes unpunished sometimes!
    It does look a bit like UoOxford had too much influence on the delivery of this vaccine. Partnering with AZ rather than Merck may have guaranteed UK production but a company more familiar with vaccine drugs might have avoided the pitfalls that AZ appear to have fallen into and which Pfizer and Moderna navigated around.

    You are right though, that for a drug that is being distributed on a non-profit basis, they are attracting a huge amount of negative attention.
    I understand from the AZN CEO interview that that part of the research had already taken place before AZN was involved.
  • pingping Posts: 3,805
    ping said:

    Attention, sports fans! Superbowl LV starts in just under one half hour.

    Any tips?

    Where’s @Tissue_Price when you need him? Iirc, NFL is his area of expertise. Probably has some lame excuse about representing the people, or something. Pft
    Anyway, I’m on tampa+3 @ evens

    Should be fun.

    Anyone else betting?
  • ping said:

    Attention, sports fans! Superbowl LV starts in just under one half hour.

    Any tips?

    Where’s @Tissue_Price when you need him? Iirc, NFL is his area of expertise. Probably has some lame excuse about representing the people, or something. Pft
    The only tip I can give re: SB LV, is that it will give the learned Dr. Green of the Spectator yet another example of "politically-correct Tik-Tok" and wokeism gone wild, when the performance of the National Anthem is accompanied by an American Sign Language (ASL) interpreter.
  • Andy_JSAndy_JS Posts: 32,588
    Cant believe people are criticising the AZ vaccine.
  • williamglennwilliamglenn Posts: 51,695
    How often do they test people who are part of the trials for covid infection? Are they only tested on demand when showing symptoms? I'm sceptical about how meaningful the reported decline in efficacy is.
  • ping said:

    ping said:

    Attention, sports fans! Superbowl LV starts in just under one half hour.

    Any tips?

    Where’s @Tissue_Price when you need him? Iirc, NFL is his area of expertise. Probably has some lame excuse about representing the people, or something. Pft
    Anyway, I’m on tampa+3 @ evens

    Should be fun.

    Anyone else betting?
    Not yours truly. But for what it's worth, most of the sports media pundits seem to agree with your assessment; they are (mostly) assuming a high-scoring game, with KC & PM scoring just a bit more than TB & TB.
  • SandyRentoolSandyRentool Posts: 22,036

    Attention, sports fans! Superbowl LV starts in just under one half hour.

    Why are Liverpool Victoria sponsoring the Superbowl?

    Hello and goodnight all.

    P.S. After 10 months, I finally finished War and Peace today. Now for something slightly shorter...
This discussion has been closed.