One conspiracy theory doing the rounds is the disease was designed to reduce China's pension costs given its ageing population, while crippling the West's economies via lockdown in the process
It seems unlikely that the Wuhan lab would do anything so detrimental to China's interest as deliberately releasing the virus into the local population. Virologists seem certain that Covid-19 has the characteristics of a naturally occurring virus originating in bats. The Wuhan was doing normal virological research into these viruses.
Accidental release of the virus into the neighbourhoood is plausible given the proximity of the lab to the origin of the outbreak, but there doesn't appear to be any evidence for this.
And there is no suggestion in the above that there is strong evidence of either.
Yeah but if the baseline is that a naturally occurring virus being studied at the lab might have been released accidentally but probably wasn't, that may say more about the sources you quote and their "position of considerable knowledge" than the practices of the lab and those of Chinese authorities.
Remember this is not a case of showing your hand, its not how it works. We don't know what raw information Western agencies have or how they have interpreted it and its unlikely to come out unless they can protect sourcing and methodology. If they can, then they will release it but how do you show say intercepts of logs of a computer for example. That's your source blown. How do you show intercepts of telephone conversations and so on.
What I'm trying to do is suggest how this may go forward, because its likely to become a bigger story and source of conflict.
Equally it doesn't take top secret intelligence to suggest that there was suppression at work. Not even the Chinese appeared to deny that they muzzled a doctor, who later died, that wanted greater attention to & warning of the severity of the situation. Also there are suggestions based on local reports that the death toll in Wuhan and wider Hubei was way way larger than the authorities stated. There are reports, on record, of concerns over the Wuhan site's bio security before this thing ever kicked off. There are stories that the EU has confirmed Chinese attempts at public disinformation in the West over SarsCoV2
None of those is intelligence agency sourced but add them up and the you'd be asking what the fuck were the Chinese at and why.
I will say this though, Western agencies try very hard to keep an eye on anything and anywhere that may be involved in dual-purpose activity. Its doubtful they'd not try to monitor the Wuhan facility and its doubtful they don't have some picture even if fragmented.
The reports of concern about (one of) the Wuhan sites’ biosecurity included requests from the Chinese for help in improving it. The details are unclear, as the US hasn’t published those cables,
One of the problems is that we’re nearly four years into a US administration almost as mendacious as the Chinese.
I'd be interesting in understanding more about that Chinese request for help. Do you have a pointer to that published anywhere?
It was in a WaPo story, not exactly slanted towards the Chinese:
https://www.washingtonpost.com/opinions/2020/04/14/state-department-cables-warned-safety-issues-wuhan-lab-studying-bat-coronaviruses/ ... The Chinese researchers at WIV were receiving assistance from the Galveston National Laboratory at the University of Texas Medical Branch and other U.S. organizations, but the Chinese requested additional help. The cables argued that the United States should give the Wuhan lab further support, mainly because its research on bat coronaviruses was important but also dangerous. As the cable noted, the U.S. visitors met with Shi Zhengli, the head of the research project, who had been publishing studies related to bat coronaviruses for many years. In November 2017, just before the U.S. officials’ visit, Shi’s team had published research showing that horseshoe bats they had collected from a cave in Yunnan province were very likely from the same bat population that spawned the SARS coronavirus in 2003....
Their slant doesn't concern me its the start point to understand more and find additional sources about the issues with the bio security.
I get that. My point was that given the tenor of the story, that detail was perhaps unlikely to be fabricated.
The concerns over Wuhan indeed Chinese labs in general working with notable pathogens appeared to have been well before the US government, who helped fund parts of the lab operations, sent their people over in 2018.
There was concern over how Wuhan got through the accreditation process and that the Chinese labs working with the pathogens didn't have good history (some notable blunders handling SARS samples) . That wasn't governments though that was voices within the scientific community. In short it was a reputation that the labs were slack.
True. But this appears to have been a worldwide problem dating back to the first SARS outbreak. And note that, unlike others deadly pathogens such as smallpox, SARS, and as late as March this year, SARS CoV-2, were permitted to be handled in much lower biosecurity level labs than the one at Wuhan - BSL2 rather than BSL4.
What looks like a very useful mouse model, from China...
Rapid adaptation of SARS-CoV-2 in BALB/c mice: Novel mouse model for vaccine efficacy https://www.biorxiv.org/content/10.1101/2020.05.02.073411v1 Coronavirus disease 2019 (COVID-19) threatens global public health and economy. In order to develop safe and effective vaccines, suitable animal models must be established. Here we report the rapid adaption of SARS-CoV-2 in BALB/c mice, based on which a convenient, economical and effective animal model was developed. Specifically, we found that mouse-adapted SARS-CoV-2 at passage 6 (MACSp6) efficiently infected both aged and young wild-type BALB/c mice, resulting in moderate pneumonia as well as inflammatory responses. The elevated infectivity of MACSp6 in mice could be attributed to the substitution of a key residue (N501Y) in the receptor-binding domain (RBD). Using this novel animal model, we further evaluated the in vivo protective efficacy of an RBD-based SARS-CoV-2 subunit vaccine, which elicited highly potent neutralizing antibodies and conferred full protection against SARS-CoV-2 MACSp6 challenge. This novel mouse model is convenient and effective in evaluating the in vivo protective efficacy of SARS-CoV-2 vaccine....
Conor Burns ferchrissakes!! This is really basic stuff: page 1 of Parliamentary Ethics for Dummies. He compounds his error, of course, by being unable to distinguish 'stationary' from 'stationery' in his letter to the Parliamentary Commissioner.
While MERS has a zoonotic origin, it seems it likely comes from live camels. And I presume many places in China have wet markets, but virus research establishments are comparatively rare. It also could have been a failed attempt to engineer a bioweapon, or to engineer something else - a vaccine, or a benign virus to test vaccines on. A bat doesn't have to escape, it could have infected a human who then went shopping at the wet market, which could be notable only as a place for people to gather.
I still think it likeliest that this has gone from bats to pangolins via the faecal-oral route and some people like eating pangolins, like with SARS1 and palm civets, but I think other possibilities and other origins for the pa demic, if not the virus, need to be considered.
I reckon yesterday was the first true sub 300 covid NHS England deaths day. We'll know if I'm right by the end of the month.
Deaths seem to be falling roughly linearly rather than exponentially.
A linear decrease is superior to an exponential decrease
It means (If true) R(t) is falling. If there was a cluster of high r places (Hospital/care homes/normal homes) that have had the populations locally removed from the infection pool via local herd immunity, the local r drops so that might feed into a global r(t) drop.
I reckon yesterday was the first true sub 300 covid NHS England deaths day. We'll know if I'm right by the end of the month.
Deaths seem to be falling roughly linearly rather than exponentially.
You wouldn't expect it to be.
If the transmission rate is 1.2 per infected person (say) you'd get exponential growth. If it's 0.8 you don't get exponential decay. Indeed you don't get linear decay - you get logarithmic decay.
"Boris" Johnson never fooled anyone. Priti Patel is a "social liberal".
These are fabulous. But don't go thinking you can never top them. That way lies decline.
I never said Patel is a social liberal I said she is more liberal than people give her credit for.
I see. She is "more liberal than people give her credit for" albeit not a "social liberal". But is she still a social conservative? Most certainly think so. Both supporters and opponents alike think that. However it sounds like you think she is less conservative socially than people give her credit for. Is she fooling that base again, I wonder.
No its not about fooling, its not all or nothing.
I think Patel is a lot more liberal than David Cameron's Home Secretary was. She has been liberalising non-EU migration in a few areas and I can't see Patel sending "Go Home" vans into minority communities.
Do you disagree with that?
I think both Priti Patel and Theresa May are socially conservative. Boris Johnson, to the extent he has political convictions, is socially liberal. Thus in this regard Patel and May are more in touch with the Tory base and the Hard Brexit base than Johnson is. Patel is therefore fooling you but not the base. Johnson is fooling the base but not you. And neither of them, nor you, are fooling me.
Patel's not fooling me. Home Secretary tends to (regardless of party) go to a social conservative, its part of the role that social liberals rarely become Home Secretary.
I think Patel is a marked improvement on Theresa May from Cameron's days and anything is a marked improvement on May's days so I think this government is, even with Patel, an improvement there. I'd rather not go back to the vile nonsense of sending Go Home vans into ethnic minority communities - May should have been sacked after that and should never have been party leader.
More than 10 times as many people in Germany have likely been infected with the coronavirus than the number of confirmed cases, researchers from the University of Bonn have concluded from a field trial in one of the worst hit towns.
More than 10 times as many people in Germany have likely been infected with the coronavirus than the number of confirmed cases, researchers from the University of Bonn have concluded from a field trial in one of the worst hit towns.
Looking at Paton`s data - looks like from a peak of 862 deaths on 8/4 we are now down to 300 (maybe slightly under 300) per day (NHS England).
While I`d say this gives government considerable scope when it looks to unwind lockdown at the end of the week, I think it will go very slowly and cautiously. Minor changes to come, I`d suggest.
More than 10 times as many people in Germany have likely been infected with the coronavirus than the number of confirmed cases, researchers from the University of Bonn have concluded from a field trial in one of the worst hit towns.
That's quite some iceberg!
My guess is that it is the same here. I think its been here since November/December
More than 10 times as many people in Germany have likely been infected with the coronavirus than the number of confirmed cases, researchers from the University of Bonn have concluded from a field trial in one of the worst hit towns.
That's quite some iceberg!
My guess is that it is the same here. I think its been here since November/December
I very, very much doubt it. But I think that there are simply many more asymptomatic carriers.
As part of the island nation's reopening plans, Ardern and her Australian counterpart, Scott Morrison, will begin talks on a cross-Tasman 'travel bubble' between the two countries.
More than 10 times as many people in Germany have likely been infected with the coronavirus than the number of confirmed cases, researchers from the University of Bonn have concluded from a field trial in one of the worst hit towns.
That's quite some iceberg!
My guess is that it is the same here. I think its been here since November/December
I wouldn't be surprised if it was already in the UK in December.
Looking at Paton`s data - looks like from a peak of 862 deaths on 8/4 we are now down to 300 (maybe slightly under 300) per day (NHS England).
While I`d say this gives government considerable scope when it looks to unwind lockdown at the end of the week, I think it will go very slowly and cautiously. Minor changes to come, I`d suggest.
usual caveats about last few days of data etc. Still surprisingly linear.
Icelandic Recode guy given all the work they have done strongly believes CV was in the UK earlier than revealed by tests and much wider spread in the early days of reporting.
More than 10 times as many people in Germany have likely been infected with the coronavirus than the number of confirmed cases, researchers from the University of Bonn have concluded from a field trial in one of the worst hit towns.
That's quite some iceberg!
My guess is that it is the same here. I think its been here since November/December
I very, very much doubt it. But I think that there are simply many more asymptomatic carriers.
While MERS has a zoonotic origin, it seems it likely comes from live camels. And I presume many places in China have wet markets, but virus research establishments are comparatively rare. It also could have been a failed attempt to engineer a bioweapon, or to engineer something else - a vaccine, or a benign virus to test vaccines on. A bat doesn't have to escape, it could have infected a human who then went shopping at the wet market, which could be notable only as a place for people to gather.
I still think it likeliest that this has gone from bats to pangolins via the faecal-oral route and some people like eating pangolins, like with SARS1 and palm civets, but I think other possibilities and other origins for the pa demic, if not the virus, need to be considered.
It is almost certainly not a bioweapon gone bad. But I like your bat to pangolin hypothesis. A recombination event in the pangolin could explain the bat backbone and the pangolin binding solution.
More than 10 times as many people in Germany have likely been infected with the coronavirus than the number of confirmed cases, researchers from the University of Bonn have concluded from a field trial in one of the worst hit towns.
That's quite some iceberg!
My guess is that it is the same here. I think its been here since November/December
I very, very much doubt it. But I think that there are simply many more asymptomatic carriers.
There is a French Doctor who thinks that it was in France in that time.
The ideal biological weapon kills the young, while leaving the infirm alone. Or, failing that, kills them all at the same rate. Something which barely affects those of working age, while hammering the retired sounds like an ideal way to solve the developed world’s dependency ratio problems, rather than a weapon of warfare.
Is this true? It's not as though much of the world economy hasn't been shutdown anyway. If China wanted to hurt the West, this seems quite a good way to go about it.
I highly doubt China would actually want to do that, but I don't think Robert's logic here is sound.
“ The most successful people I know never blame others, even when it’s others’ fault. If they hire someone who turns out to be a disaster, they blame themselves for making a bad hiring decision, not the person who was a disaster.“
I had a discussion about this a decade ago with a work colleague. I said I did feel exactly the way Robert describes, everything ultimately is my fault, If I ask someone to do something and they do it badly, I should have asked someone better suited to it... they couldn’t see it - obviously I hadn’t explained it well enough!
Why aren’t I one of the most successful people Robert doesn’t really know?!
More than 10 times as many people in Germany have likely been infected with the coronavirus than the number of confirmed cases, researchers from the University of Bonn have concluded from a field trial in one of the worst hit towns.
“ The most successful people I know never blame others, even when it’s others’ fault. If they hire someone who turns out to be a disaster, they blame themselves for making a bad hiring decision, not the person who was a disaster.“
I had a discussion about this a decade ago with a work colleague. I said I did feel exactly the way Robert describes, everything ultimately is my fault, If I ask someone to do something and they do it badly, I should have asked someone better suited to it... they couldn’t see it - obviously I hadn’t explained it well enough!
Why aren’t I one of the most successful people Robert doesn’t really know?!
Conor Burns ferchrissakes!! This is really basic stuff: page 1 of Parliamentary Ethics for Dummies. He compounds his error, of course, by being unable to distinguish 'stationary' from 'stationery' in his letter to the Parliamentary Commissioner.
Typical of the low calibre non-entities that are put into positions of responsibility by the Johnson/Cummings government. What a numpty.
Not sure China deliberately wanting to damage the West conspiracy theory holds much water.
Before CV, China were winning on a global stage without having to start any new wars. They have evolved from just a place for the West to make cheap crap to now a place the West relies on for so many things.
In recent years, Chinese companies have been heavily investing in Western companies and also own a lot of the West debt.
Totally torpedoing the Wests economy seems massively counter-productive.
They didn't need to do anything, another 10-15 years of the rate of progress and they would easily be the worlds super power.
Now, I think we are going to see a big shake up in some sectors, where governments are going to mandate that industries cannot be beholden to China factory output.
Yesterday I had to explain to my football team on our WhatsApp group that the number announced by the govt each day isn’t the amount of people who died yesterday, and shared a graph showing the decline from the peak on 8th April... none of them had any idea, they were genuinely amazed, and kind of got angry that the govt had been ‘lying’. It seemed to weaken their resolve to obey the lockdown I must say.
I thought everyone knew. Just shows the difference between the politically engaged and Joe public I think.
Yesterday I had to explain to my football team on our WhatsApp group that the number announced by the govt each day isn’t the amount of people who died yesterday, and shared a graph showing the decline from the peak on 8th April... none of them had any idea, they were genuinely amazed, and kind of got angry that the govt had been ‘lying’. It seemed to weaken their resolve to obey the lockdown I must say.
I thought everyone knew. Just shows the difference between the politically engaged and Joe public I think.
Well the government themselves don't help with the chart they put out everyday at the press conference and of course the media have been absolute shit show on stats.
“ The most successful people I know never blame others, even when it’s others’ fault. If they hire someone who turns out to be a disaster, they blame themselves for making a bad hiring decision, not the person who was a disaster.“
I had a discussion about this a decade ago with a work colleague. I said I did feel exactly the way Robert describes, everything ultimately is my fault, If I ask someone to do something and they do it badly, I should have asked someone better suited to it... they couldn’t see it - obviously I hadn’t explained it well enough!
Why aren’t I one of the most successful people Robert doesn’t really know?!
Because you spend too much time blaming the EU for, well, everything. No doubt you will continue to do so for years after we leave. TheEU are the equivalent of the global conspiracy. The other answer to your question is that you possibly spend too much time on here. Admittedly not as much time as one other EU blamer I could name, but it might be part of your answer. On which subject, I'd better do some work!
The ideal biological weapon kills the young, while leaving the infirm alone. Or, failing that, kills them all at the same rate. Something which barely affects those of working age, while hammering the retired sounds like an ideal way to solve the developed world’s dependency ratio problems, rather than a weapon of warfare.
Is this true? It's not as though much of the world economy hasn't been shutdown anyway. If China wanted to hurt the West, this seems quite a good way to go about it.
I highly doubt China would actually want to do that, but I don't think Robert's logic here is sound.
I wrote a chapter in a book a couple of years back saying that the term biological weapon is ambiguous: 1. Is it a weapon for use on the battlefield against enemy troops within a logical military dogma? 2. Is it a weapon of territorial denial (e.g. by contaminating logistics hubs) 3. Is it a weapon of assassination? (Georgi Markov) 4. Is it a weapon of mass disruption/terror? (think Amerithrax letters) 5. Is it a doomsday weapon? 6. Is it a psychological weapon? (e.g. Saddam Hussein - we don't need it, we just need others to think we might). 7. Is it a weapon of economic attrition? (e.g. Saddam's hunt for weapons to take out Iran's crops)
Personally, I'd agree with Robert that COVID is useless in all categories because, while it might seem to do the job in some of those categories, China had no defence for it itself and had no way of knowing ahead of time whether or not it would differentially affect countries.
"Social distancing orders for people to keep two metres apart to stop the spread of coronavirus is not based on any scientific research, a government adviser has said.
Robert Dingwall, from the New and Emerging Respiratory Virus Threats Advisory Group (Nervtag), said the rule was 'conjured up out of nowhere'.
The sociology professor at Nottingham Trent University said scientific evidence supports a one-metre gap, but the two-metre advice was a 'rule of thumb'."
Here's the thing, you see. Michael Gove has probably done more for Holocaust education and the Jewish community in Britain than any senior politician other than Gordon Brown. It's obvious to anyone why he would have read the work of a Holocaust denier.
Owen Jones, on the other hand, was an actual cheerleader for Jeremy Corbyn - a man described by one of his own MPs as a "racist antisemite". If Jones had his way, that same Jeremy Corbyn would be in Number Ten right now.
Twitter can be annoying, infuriating and sometimes plain pointless. But sometimes it can reveal truths. And in one stupid tweet last night, Owen Jones confirmed a truth about himself and his fellow hard left travellers: that their true ideology is hypocrisy.
"Social distancing orders for people to keep two metres apart to stop the spread of coronavirus is not based on any scientific research, a government adviser has said.
Robert Dingwall, from the New and Emerging Respiratory Virus Threats Advisory Group (Nervtag), said the rule was 'conjured up out of nowhere'.
The sociology professor at Nottingham Trent University said scientific evidence supports a one-metre gap, but the two-metre advice was a 'rule of thumb'."
Well given nobody even really knows how this thing is transmitted (or rather what are the highest probability routes for transmission), of course it is. It is clearly just based on the presumption, tell people to stay a long way apart, then if they get a bit closer, they are probably still far enough.
And even then the science is far from settled. It really depends on small droplet vs large droplet transmission. If it is one, 2m isn't anywhere near enough. Basically anybody in an enclosed environment is in danger.
Here's the thing, you see. Michael Gove has probably done more for Holocaust education and the Jewish community in Britain than any senior politician other than Gordon Brown. It's obvious to anyone why he would have read the work of a Holocaust denier.
Owen Jones, on the other hand, was an actual cheerleader for Jeremy Corbyn - a man described by one of his own MPs as a "racist antisemite". If Jones had his way, that same Jeremy Corbyn would be in Number Ten right now.
Twitter can be annoying, infuriating and sometimes plain pointless. But sometimes it can reveal truths. And in one stupid tweet last night, Owen Jones confirmed a truth about himself and his fellow hard left travellers: that their true ideology is hypocrisy.
It's similar to the student union at oxford banning works by white authors. Quite how they plan to learn without studying all aspects of society is beyond me.
Here's the thing, you see. Michael Gove has probably done more for Holocaust education and the Jewish community in Britain than any senior politician other than Gordon Brown. It's obvious to anyone why he would have read the work of a Holocaust denier.
Owen Jones, on the other hand, was an actual cheerleader for Jeremy Corbyn - a man described by one of his own MPs as a "racist antisemite". If Jones had his way, that same Jeremy Corbyn would be in Number Ten right now.
Twitter can be annoying, infuriating and sometimes plain pointless. But sometimes it can reveal truths. And in one stupid tweet last night, Owen Jones confirmed a truth about himself and his fellow hard left travellers: that their true ideology is hypocrisy.
In 2017, a team from the Institute announced that coronaviruses found in horseshoe bats at a cave in Yunnan contain all the genetic pieces of the SARS virus, and hypothesized that the direct progenitor of the human virus originated in this cave. The team, who spent five years sampling the bats in the cave, noted the presence of a village only a kilometer away, and warned of "the risk of spillover into people and emergence of a disease similar to SARS".[19][22]
In December 2019, cases of pneumonia associated with an unknown coronavirus were reported to health authorities in Wuhan. The Institute checked its coronavirus collection and found the new virus was 96 percent identical to a sample its researchers had taken from horseshoe bats in southwest China.[23]
So the lab escape theory really requires no extra assumptions at all, or at least not the ones proposed in the header. We know for certain that the lab was investigating, and had a collection of, bat-borne CV. Nor does the theory require a bat to escape: it might have done, or a researcher might have smuggled one out to eat or to sell, but it's much more likely a researcher was unknowingly infected in the lab and took the virus home when s/he left for the night.
So it is unknowable. What would help is some numbers: how many live bats turned over per day in wet market, how many of those bats harbour coronavirus, vs how many people potentially exp[osed to how many CVs in lab. I don't even know, for instance, whether when you get a bat in a virology lab you harvest its viruses and knock it on the head, or keep it in a cage.
Given the state of our knowledge I'd say it was 50/50 pending being given some numbers.
We should stop conflating "lab escape" with "deliberately engineered" which is an insane idea.
More than 10 times as many people in Germany have likely been infected with the coronavirus than the number of confirmed cases, researchers from the University of Bonn have concluded from a field trial in one of the worst hit towns.
That's quite some iceberg!
My guess is that it is the same here. I think its been here since November/December
ZOE, the people doing the Covid tracker, reckon there are currently 288,000 people in the UK with symptomatic Covid, down from a peak of over 2,000,000 on 1April
What looks like a very useful mouse model, from China...
Rapid adaptation of SARS-CoV-2 in BALB/c mice: Novel mouse model for vaccine efficacy https://www.biorxiv.org/content/10.1101/2020.05.02.073411v1 Coronavirus disease 2019 (COVID-19) threatens global public health and economy. In order to develop safe and effective vaccines, suitable animal models must be established. Here we report the rapid adaption of SARS-CoV-2 in BALB/c mice, based on which a convenient, economical and effective animal model was developed. Specifically, we found that mouse-adapted SARS-CoV-2 at passage 6 (MACSp6) efficiently infected both aged and young wild-type BALB/c mice, resulting in moderate pneumonia as well as inflammatory responses. The elevated infectivity of MACSp6 in mice could be attributed to the substitution of a key residue (N501Y) in the receptor-binding domain (RBD). Using this novel animal model, we further evaluated the in vivo protective efficacy of an RBD-based SARS-CoV-2 subunit vaccine, which elicited highly potent neutralizing antibodies and conferred full protection against SARS-CoV-2 MACSp6 challenge. This novel mouse model is convenient and effective in evaluating the in vivo protective efficacy of SARS-CoV-2 vaccine....
Wuhan did gain of function work on mouse models with coronaviruses ... Just saying ...
“ The most successful people I know never blame others, even when it’s others’ fault. If they hire someone who turns out to be a disaster, they blame themselves for making a bad hiring decision, not the person who was a disaster.“
I had a discussion about this a decade ago with a work colleague. I said I did feel exactly the way Robert describes, everything ultimately is my fault, If I ask someone to do something and they do it badly, I should have asked someone better suited to it... they couldn’t see it - obviously I hadn’t explained it well enough!
Why aren’t I one of the most successful people Robert doesn’t really know?!
Because you spend too much time blaming the EU for, well, everything. No doubt you will continue to do so for years after we leave. TheEU are the equivalent of the global conspiracy. The other answer to your question is that you possibly spend too much time on here. Admittedly not as much time as one other EU blamer I could name, but it might be part of your answer. On which subject, I'd better do some work!
I don’t blame the EU for anything, and never have. Read more carefully
“ The most successful people I know never blame others, even when it’s others’ fault. If they hire someone who turns out to be a disaster, they blame themselves for making a bad hiring decision, not the person who was a disaster.“
I had a discussion about this a decade ago with a work colleague. I said I did feel exactly the way Robert describes, everything ultimately is my fault, If I ask someone to do something and they do it badly, I should have asked someone better suited to it... they couldn’t see it - obviously I hadn’t explained it well enough!
Why aren’t I one of the most successful people Robert doesn’t really know?!
Because you spend too much time blaming the EU for, well, everything. No doubt you will continue to do so for years after we leave. TheEU are the equivalent of the global conspiracy. The other answer to your question is that you possibly spend too much time on here. Admittedly not as much time as one other EU blamer I could name, but it might be part of your answer. On which subject, I'd better do some work!
I don’t blame the EU for anything, and never have. Read more carefully
Here's the thing, you see. Michael Gove has probably done more for Holocaust education and the Jewish community in Britain than any senior politician other than Gordon Brown. It's obvious to anyone why he would have read the work of a Holocaust denier.
Owen Jones, on the other hand, was an actual cheerleader for Jeremy Corbyn - a man described by one of his own MPs as a "racist antisemite". If Jones had his way, that same Jeremy Corbyn would be in Number Ten right now.
Twitter can be annoying, infuriating and sometimes plain pointless. But sometimes it can reveal truths. And in one stupid tweet last night, Owen Jones confirmed a truth about himself and his fellow hard left travellers: that their true ideology is hypocrisy.
All hyper partisan politicals, right or left, require hypocrisy in order to operate. This is less true of Jones than most - who for example has been pretty good on antisemitism - whilst still being true of him.
What looks like a very useful mouse model, from China...
Rapid adaptation of SARS-CoV-2 in BALB/c mice: Novel mouse model for vaccine efficacy https://www.biorxiv.org/content/10.1101/2020.05.02.073411v1 Coronavirus disease 2019 (COVID-19) threatens global public health and economy. In order to develop safe and effective vaccines, suitable animal models must be established. Here we report the rapid adaption of SARS-CoV-2 in BALB/c mice, based on which a convenient, economical and effective animal model was developed. Specifically, we found that mouse-adapted SARS-CoV-2 at passage 6 (MACSp6) efficiently infected both aged and young wild-type BALB/c mice, resulting in moderate pneumonia as well as inflammatory responses. The elevated infectivity of MACSp6 in mice could be attributed to the substitution of a key residue (N501Y) in the receptor-binding domain (RBD). Using this novel animal model, we further evaluated the in vivo protective efficacy of an RBD-based SARS-CoV-2 subunit vaccine, which elicited highly potent neutralizing antibodies and conferred full protection against SARS-CoV-2 MACSp6 challenge. This novel mouse model is convenient and effective in evaluating the in vivo protective efficacy of SARS-CoV-2 vaccine....
Wuhan did gain of function work on mouse models with coronaviruses ... Just saying ...
Yesterday I had to explain to my football team on our WhatsApp group that the number announced by the govt each day isn’t the amount of people who died yesterday, and shared a graph showing the decline from the peak on 8th April... none of them had any idea, they were genuinely amazed, and kind of got angry that the govt had been ‘lying’. It seemed to weaken their resolve to obey the lockdown I must say.
I thought everyone knew. Just shows the difference between the politically engaged and Joe public I think.
No - everyone doesn`t know - I`ve had similar conversations with people who think the deaths are much - much - higher than is actually the case. Some think the numbers are still rising (listening to BBC sometimes, I can`t blame them - and I`m not a habitual knocker of the BBC).
That`s in terms of numbers. If you talk in percentages they believe you even less. Maths ignorance and believing what they read in the media, I think. The government have got a heck of a job in persuading people to go back to work. That over 99% survive the virus just isn`t appreciated by many out there - doesn`t sound as scary as "900 people died today".
I reckon yesterday was the first true sub 300 covid NHS England deaths day. We'll know if I'm right by the end of the month.
Deaths seem to be falling roughly linearly rather than exponentially.
I think a long tail is to be expected, you've also got differences in 'coverage' of different parts of the country.
Yes that's what I'd expect, exponential declines would give a long tail but we're not getting that right now we're currently got linear declines it seems which is good news. Now that numbers are lower the rate of decline should be falling (exponential) but it doesn't seem to be.
Jeremy Corbyn's conspiracy theorist brother, 73, leads his third anti-lockdown protest after claiming Covid is being used by the 'new world order' to inject Britons with MICROCHIPS
That's what I was just saying about linear rather than exponential decline it seems. From the peak it seems like its taken roughly 8 days per 200 deaths to fall off the daily rate. At this rate there could be no deaths by the middle of next week (not that I'm expecting that).
I reckon yesterday was the first true sub 300 covid NHS England deaths day. We'll know if I'm right by the end of the month.
Deaths seem to be falling roughly linearly rather than exponentially.
I think a long tail is to be expected, you've also got differences in 'coverage' of different parts of the country.
Yes that's what I'd expect, exponential declines would give a long tail but we're not getting that right now we're currently got linear declines it seems which is good news. Now that numbers are lower the rate of decline should be falling (exponential) but it doesn't seem to be.
I get what you're saying but it's more normal to describe the decay graph you're describing as logarithmic rather than exponential.
What makes me laugh more isn't the idea of Hilldog being parachuted in, its the DNC holding a virtual convention where delegate after delegate avows and affirms that Biden is the Best Person to be the candidate. Against any other GOP candidate Biden would not be anywhere near the ticket for all the obvious reasons. Are the DNC still delusional enough to think that because Trump is So Hated they can run a geriatric dodgepot who falls asleep on TV sets whilst they interview him about his sexual abuse of power allegations?
I also don't see this as a blame allocation game, because it comes down to, it's the Chinese authorities to blame for running disgusting wet markets vs it's the Chinese authorities to blame for running insecure biolabs. As far as anyone else is concerned, we should have been better prepared irrespective of how it originated.
More than 10 times as many people in Germany have likely been infected with the coronavirus than the number of confirmed cases, researchers from the University of Bonn have concluded from a field trial in one of the worst hit towns.
That's quite some iceberg!
My guess is that it is the same here. I think its been here since November/December
I very, very much doubt it. But I think that there are simply many more asymptomatic carriers.
Says PB's resident eminent virologist.
I make no pretensions to be a virologist but Occam's Razor makes it very, very unlikely to me.
Given how contagious this disease is and how quickly it spreads and how quickly it can lead to a spike in deaths and hospital admissions then if this was here back in November then even if we didn't realise that is why people were sick why didn't we a spike in hospital admissions? Why didn't we see a spike in deaths? Why did early testing have over 95% test negative for so long? Why did we only see a spike in deaths a couple of weeks ago when the outbreak was known to happen?
The idea that it was here in November but people weren't dying from it until March just seems illogical. Why were death rates unmoved from average (or ever down from average) over the whole winter until March?
I'm no virologist and don't claim to be but I can read statistics and that just makes zero sense.
"Social distancing orders for people to keep two metres apart to stop the spread of coronavirus is not based on any scientific research, a government adviser has said.
Robert Dingwall, from the New and Emerging Respiratory Virus Threats Advisory Group (Nervtag), said the rule was 'conjured up out of nowhere'.
The sociology professor at Nottingham Trent University said scientific evidence supports a one-metre gap, but the two-metre advice was a 'rule of thumb'."
Well given nobody even really knows how this thing is transmitted (or rather what are the highest probability routes for transmission), of course it is. It is clearly just based on the presumption, tell people to stay a long way apart, then if they get a bit closer, they are probably still far enough.
And even then the science is far from settled. It really depends on small droplet vs large droplet transmission. If it is one, 2m isn't anywhere near enough. Basically anybody in an enclosed environment is in danger.
There is nothing definite with this virus. It will take decades of study to actually work out what has been going on with it and how it infects and affects people and what control measures actually worked and what didn't.
I reckon yesterday was the first true sub 300 covid NHS England deaths day. We'll know if I'm right by the end of the month.
Deaths seem to be falling roughly linearly rather than exponentially.
You wouldn't expect it to be.
If the transmission rate is 1.2 per infected person (say) you'd get exponential growth. If it's 0.8 you don't get exponential decay. Indeed you don't get linear decay - you get logarithmic decay.
As I've pointed out before, people don't die on a fixed day after infection. Therefore the decay period in the death distribution isn't just a delayed version of the new cases distribution: it's the latter overlaid with a (probably quite wide and flattish) distribution of the number of days between infection and death.
Like masks, all these references to requiring hand sanitisers everywhere. Can you get hand sanitiser anywhere at the moment?
Shopping news. I've just bought my first ever hand sanitiser from Sainsbury's. The last on the shelf. 50ml of Bulgarian germ-zapping goodness. No mention of viruses but there is alcohol in there. There is a space for the "best before" date but nothing has been stamped there.
A very short queue to get in but the shelves seemed emptier than last week.
You know soap and water can do the trick just as well?
I reckon yesterday was the first true sub 300 covid NHS England deaths day. We'll know if I'm right by the end of the month.
Deaths seem to be falling roughly linearly rather than exponentially.
I think a long tail is to be expected, you've also got differences in 'coverage' of different parts of the country.
Yes that's what I'd expect, exponential declines would give a long tail but we're not getting that right now we're currently got linear declines it seems which is good news. Now that numbers are lower the rate of decline should be falling (exponential) but it doesn't seem to be.
I get what you're saying but it's more normal to describe the decay graph you're describing as logarithmic rather than exponential.
Comments
https://twitter.com/Starcourse/status/1257277717944426497?s=20
https://twitter.com/Starcourse/status/1257278835873251331?s=20
https://twitter.com/Starcourse/status/1257278392354975746?s=20
Lock these bellends up and transport them to the Pitcairn Islands.
(FPT) True.
But this appears to have been a worldwide problem dating back to the first SARS outbreak. And note that, unlike others deadly pathogens such as smallpox, SARS, and as late as March this year, SARS CoV-2, were permitted to be handled in much lower biosecurity level labs than the one at Wuhan - BSL2 rather than BSL4.
Laboratory safety aspects of SARS at Biosafety Level 2.
https://www.ncbi.nlm.nih.gov/pubmed/15098644
Laboratory Biosafety Recommendations for SARS-CoV-2 and COVID-19
https://www.labconco.com/articles/laboratory-biosafety-recommendations-for-sars-co
Rapid adaptation of SARS-CoV-2 in BALB/c mice: Novel mouse model for vaccine efficacy
https://www.biorxiv.org/content/10.1101/2020.05.02.073411v1
Coronavirus disease 2019 (COVID-19) threatens global public health and economy. In order to develop safe and effective vaccines, suitable animal models must be established. Here we report the rapid adaption of SARS-CoV-2 in BALB/c mice, based on which a convenient, economical and effective animal model was developed. Specifically, we found that mouse-adapted SARS-CoV-2 at passage 6 (MACSp6) efficiently infected both aged and young wild-type BALB/c mice, resulting in moderate pneumonia as well as inflammatory responses. The elevated infectivity of MACSp6 in mice could be attributed to the substitution of a key residue (N501Y) in the receptor-binding domain (RBD). Using this novel animal model, we further evaluated the in vivo protective efficacy of an RBD-based SARS-CoV-2 subunit vaccine, which elicited highly potent neutralizing antibodies and conferred full protection against SARS-CoV-2 MACSp6 challenge. This novel mouse model is convenient and effective in evaluating the in vivo protective efficacy of SARS-CoV-2 vaccine....
It's a little more than just that - it's basically Trump's entire re-election strategy.
See:
https://twitter.com/cricketwyvern/status/1257300183466962947/photo/1
I'm not saying both procedures in Chinese (and other labs) and the operation of wet markets aren't valid issues in the aftermath of this.
But it's also very obvious indeed that it's extremely helpful to those struggling with questions about their own response to up the rhetoric on this.
I still think it likeliest that this has gone from bats to pangolins via the faecal-oral route and some people like eating pangolins, like with SARS1 and palm civets, but I think other possibilities and other origins for the pa demic, if not the virus, need to be considered.
It means (If true) R(t) is falling. If there was a cluster of high r places (Hospital/care homes/normal homes) that have had the populations locally removed from the infection pool via local herd immunity, the local r drops so that might feed into a global r(t) drop.
If the transmission rate is 1.2 per infected person (say) you'd get exponential growth. If it's 0.8 you don't get exponential decay. Indeed you don't get linear decay - you get logarithmic decay.
I think Patel is a marked improvement on Theresa May from Cameron's days and anything is a marked improvement on May's days so I think this government is, even with Patel, an improvement there. I'd rather not go back to the vile nonsense of sending Go Home vans into ethnic minority communities - May should have been sacked after that and should never have been party leader.
While I`d say this gives government considerable scope when it looks to unwind lockdown at the end of the week, I think it will go very slowly and cautiously. Minor changes to come, I`d suggest.
https://www.carnivalcorp.com/news-releases/news-release-details/carnival-cruise-line-announces-plan-phase-service
Of all the cognitive biases, the attribution bias is my favorite. If you mess up, it's your fault. If I mess up, it's because circumstances.
usual caveats about last few days of data etc. Still surprisingly linear.
Spreadsheet at
https://drive.google.com/open?id=1ZIQAac0pm-Ihgw8wS45zfnAtjrJHJGS_
Is this true? It's not as though much of the world economy hasn't been shutdown anyway. If China wanted to hurt the West, this seems quite a good way to go about it.
I highly doubt China would actually want to do that, but I don't think Robert's logic here is sound.
I had a discussion about this a decade ago with a work colleague. I said I did feel exactly the way Robert describes, everything ultimately is my fault, If I ask someone to do something and they do it badly, I should have asked someone better suited to it... they couldn’t see it - obviously I hadn’t explained it well enough!
Why aren’t I one of the most successful people Robert doesn’t really know?!
"Well, this will not end well"
Is covering the NHS app this afternoon on his header (as well as other virus stuff).
Good questions being asked about a 'honeypot' centralised database vs Apple/Google.
Toby questions whether it will even work.
Before CV, China were winning on a global stage without having to start any new wars. They have evolved from just a place for the West to make cheap crap to now a place the West relies on for so many things.
In recent years, Chinese companies have been heavily investing in Western companies and also own a lot of the West debt.
Totally torpedoing the Wests economy seems massively counter-productive.
They didn't need to do anything, another 10-15 years of the rate of progress and they would easily be the worlds super power.
Now, I think we are going to see a big shake up in some sectors, where governments are going to mandate that industries cannot be beholden to China factory output.
I thought everyone knew. Just shows the difference between the politically engaged and Joe public I think.
1. Is it a weapon for use on the battlefield against enemy troops within a logical military dogma?
2. Is it a weapon of territorial denial (e.g. by contaminating logistics hubs)
3. Is it a weapon of assassination? (Georgi Markov)
4. Is it a weapon of mass disruption/terror? (think Amerithrax letters)
5. Is it a doomsday weapon?
6. Is it a psychological weapon? (e.g. Saddam Hussein - we don't need it, we just need others to think we might).
7. Is it a weapon of economic attrition? (e.g. Saddam's hunt for weapons to take out Iran's crops)
Personally, I'd agree with Robert that COVID is useless in all categories because, while it might seem to do the job in some of those categories, China had no defence for it itself and had no way of knowing ahead of time whether or not it would differentially affect countries.
Robert Dingwall, from the New and Emerging Respiratory Virus Threats Advisory Group (Nervtag), said the rule was 'conjured up out of nowhere'.
The sociology professor at Nottingham Trent University said scientific evidence supports a one-metre gap, but the two-metre advice was a 'rule of thumb'."
https://www.dailymail.co.uk/news/article-8256109/Social-distancing-two-metres-apart-based-figure-says-government-adviser.html
Owen Jones, on the other hand, was an actual cheerleader for Jeremy Corbyn - a man described by one of his own MPs as a "racist antisemite". If Jones had his way, that same Jeremy Corbyn would be in Number Ten right now.
Twitter can be annoying, infuriating and sometimes plain pointless. But sometimes it can reveal truths. And in one stupid tweet last night, Owen Jones confirmed a truth about himself and his fellow hard left travellers: that their true ideology is hypocrisy.
https://www.thejc.com/comment/comment/one-stupid-tweet-by-owen-jones-confirms-all-you-need-to-know-about-the-hard-left-1.499433
And even then the science is far from settled. It really depends on small droplet vs large droplet transmission. If it is one, 2m isn't anywhere near enough. Basically anybody in an enclosed environment is in danger.
In December 2019, cases of pneumonia associated with an unknown coronavirus were reported to health authorities in Wuhan. The Institute checked its coronavirus collection and found the new virus was 96 percent identical to a sample its researchers had taken from horseshoe bats in southwest China.[23]
https://en.wikipedia.org/wiki/Wuhan_Institute_of_Virology
So the lab escape theory really requires no extra assumptions at all, or at least not the ones proposed in the header. We know for certain that the lab was investigating, and had a collection of, bat-borne CV. Nor does the theory require a bat to escape: it might have done, or a researcher might have smuggled one out to eat or to sell, but it's much more likely a researcher was unknowingly infected in the lab and took the virus home when s/he left for the night.
We have two bat/human interfaces, market and lab. Arguments for market: more people, no biosecurity. Arguments for lab: large, dedicated collection of bat viruses. As for raw numbers of bats, who knows? Argument against lab: biosecurity. Counter argument to that: Chinese biosecurity is shit and was known to be shit years ago: https://www.express.co.uk/news/world/1255805/coronavirus-wuhan-biosafety-lab-china-monkeys-sars-disease-virus-spt
So it is unknowable. What would help is some numbers: how many live bats turned over per day in wet market, how many of those bats harbour coronavirus, vs how many people potentially exp[osed to how many CVs in lab. I don't even know, for instance, whether when you get a bat in a virology lab you harvest its viruses and knock it on the head, or keep it in a cage.
Given the state of our knowledge I'd say it was 50/50 pending being given some numbers.
We should stop conflating "lab escape" with "deliberately engineered" which is an insane idea.
Does anyone want to break the news to him?
That`s in terms of numbers. If you talk in percentages they believe you even less. Maths ignorance and believing what they read in the media, I think. The government have got a heck of a job in persuading people to go back to work. That over 99% survive the virus just isn`t appreciated by many out there - doesn`t sound as scary as "900 people died today".
https://twitter.com/thehill/status/1257050566817185792
https://www.dailymail.co.uk/news/article-8284129/Jeremy-Corbyns-brother-73-leads-anti-lockdown-protest-Covid-19-conspiracy-theory.html
David Icke has been on the phone complaining that this guy is making him look too sane for his USP to enable him to flog his books.
https://twitter.com/stephenpollard/status/1257285910883958785?s=20
Given how contagious this disease is and how quickly it spreads and how quickly it can lead to a spike in deaths and hospital admissions then if this was here back in November then even if we didn't realise that is why people were sick why didn't we a spike in hospital admissions? Why didn't we see a spike in deaths? Why did early testing have over 95% test negative for so long? Why did we only see a spike in deaths a couple of weeks ago when the outbreak was known to happen?
The idea that it was here in November but people weren't dying from it until March just seems illogical. Why were death rates unmoved from average (or ever down from average) over the whole winter until March?
I'm no virologist and don't claim to be but I can read statistics and that just makes zero sense.
https://www.youtube.com/watch?v=yO3Gcb6Nyw4