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Powerful front page from the Daily Mail as UK COVID deaths top 100k – politicalbetting.com

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  • AnabobazinaAnabobazina Posts: 23,486
    Foxy said:

    Foxy said:

    RobD said:

    Foxy said:

    Best performing countries for Covid vaccine doses given out:

    Israel (9.05 million) 47.90 per 100 population
    UAE (9.77 million) 27.107 per 100 population
    United Kingdom (67 million) 10.79 per 100 population

    ...

    European Union (446 million) 2.11 per 100 population

    Still @Nigel_Foremain reckons "big" "muscle" works when it comes to pharmaceuticals. "Big" doesn't work. "Muscle" doesn't work.

    Small countries nimbly looking after themselves works.

    Bear in mind, that % covers the entire population. But 21% of the UK population is under 18. So, as we have no plans to vaccinate Da Yoof yet, we have actually jabbed 10.79m of the total 53m pool - we have done over 20% of the adult population of the UK.

    And we have probably jabbed a million more by now - so we are at 22.5% as of this moment.
    Half-jabbed...
    Which we are repeatedly told confer the majority of the protection.
    Yes, we are repeatedly told that in the UK. A wing and a prayer springs to mind.
    C'mon, you're not subscribing to that BMA nonsense are you? There's MASSIVE evidence around the world that the first jab, certainly of the Pfizer/BioNTech vaccine, provides a very high degree of protection, both in the published clinical trial data and in the real-world experience coming out of Israel. For the AZ vaccine, the boss himself confirmed the same yesterday.
    As I said, it may be a gamble that comes off, but it is a gamble.

    Israel is sticking to the protocol, so we have to wait until March to see if our different protocol works.
    Isn't sticking to three weeks a gamble on the other side of the bet though? You are precluding people from Jab 1 to give others Jab 2.

    That's a gamble in and of itself.
  • PulpstarPulpstar Posts: 78,204

    England only vaccination data out

    1st dose 2nd dose
    Total 259306 1001
    East Of England 29244 47
    London 43555 445
    Midlands 41813 131
    North East And Yorkshire 38513 56
    North West 35271 95
    South East 39181 177
    South West 29908 47

    Clearly vaccine supply shortage hitting home. Time to go full Cartman EU on Pfizer and AZN.
    ...

  • malcolmgmalcolmg Posts: 43,355
    RobD said:

    Foxy said:

    RobD said:

    Foxy said:

    Andy_JS said:

    Psizer: first jab gives 90% protection, second gives 94% protection. You can see why they're delaying the second one.

    The difference in antibodies a week after the second injection is 10 fold.
    Israel finds single dose gives high resistance

    https://www.ft.com/content/4d9fe80d-e604-4bbe-b0f8-fd4b8df9b7f1
    And went ahead with the second dose on schedule.
    So? We're discussing the effectiveness of a single jab.
    LOL a medical expert as well as a Scotch one, what other talents do you hide Rob. You tell that consultant he does not know what he is talking about , daring to think he knows better than you.
  • OnlyLivingBoyOnlyLivingBoy Posts: 15,798
    TOPPING said:

    TOPPING said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Yes it is significant.

    @MarqueeMark will fill you in on the details.
    This is what my conference call was about.

    We are more f*cked than a stepmom on Pornhub when our 18 month clearing exemption ends and it isn't permanently renewed.

    But those of us in the financial services sector we rank lower than fish.
    Other than a hostile act of petty vengeance what reason would tbe EU have to give clearing equivalence to US but not UK?
    Because we haven't been negotiating for it?
    Fish >> Finance remember.
  • HYUFDHYUFD Posts: 123,127
    Cruz playing the 'man of the people' card

    https://twitter.com/SenTedCruz/status/1354429807300374531?s=20
  • FrancisUrquhartFrancisUrquhart Posts: 82,092
    edited January 2021
    The deviation is a calculated risk, in an ideal world AZN would be redoing their trial before approval....but the world isn't ideal, we have to get on with it and in reality i wouldn't be surprised in we are repeating this process next year. AZN said they are already working on a new vaccine.
  • kinabalukinabalu Posts: 42,213
    edited January 2021

    kinabalu said:

    RobD said:

    kinabalu said:

    RobD said:

    kinabalu said:

    ydoethur said:

    ydoethur said:

    eek said:

    Nigelb said:


    It would only be interesting, indeed astonishing, if such caveats weren't in the contract.

    It is completely inconceivable that the contract wouldn't include lots of such caveats. There is absolutely no way AZ would have given a firm commitment on delivery dates for a brand-new vaccine, involving new production facilities and dependent on other suppliers who themselves were also doing things for the first time, all in a super-fast timescale.
    As AZ CEO has continually stated the contract is based on best endeavors.

    I'm actually surprised how polite he is being in public considering the games the EU seem to be playing.
    https://twitter.com/danielboffey/status/1354401225995911169?s=20
    I don't know what the EU think they're playing at. They really are in a negotiation where AZ hold all the cards. After all, if the EU get too bolshie AZ have the option to simply walk away from the contract, close their European factory and concentrate on other markets.

    And there is exactly feck all the EU can do about it.

    So the 'win' here for the EU is they accept a lower delivery than they want, and the lose is that they get none at all.
    Wrong. The EU is one of the largest markets for pharmaceuticals in the world. That gives them a lot of muscle. AZ will not want to antagonise them more than necessary, so no, AZ do not hold all the cards, far from it.
    So - just to be clear - the EU might ban AZ from operating in the EU altogether if they decide to abrogate a contract?

    Which would cause no medicine shortages of any kind, I trust?

    The EU are behaving like complete fools. It's like watching the DUP over Theresa May's deal - only worse, because you expect the DUP to behave like idiots.
    The EU feels that AZ have legged them over. So they are making a fuss.
    A resolution will be found that puts the EU in a better position than if they had not made a fuss.
    This is what I predict. Bet I'm right.
    At the detriment to who?
    I fear it might be you, Rob. But let's hope not.
    It was a legitimate question. The EU are seeking to divert supplies rightfully destined for the UK.
    Not really. That's a simplistic and jaundiced view. They are "rightfully" seeking to reduce their shortfall. In general, with fixed vaccine supply, every shot someone has means somebody else did not have it. Why are we diverting jabs from Italy? Why is Israel diverting jabs from us? Etc. It all depends on the contracts, the money, the moral view, the WHO, the balance of power, the politics etc etc. Bottom line is as I summarized and people should stop sanctimoniously moaning unless and until something that warrants it occurs. Which it hasn't yet. All that's happening is a frenzy of europhobes mutually wanking each other off and wallowing in europhobia. I'm finding it infantile and tedious.
    "Rightfully"?

    The EU signed their contracts three months late. It isn't europhobia to point this out.

    Had Johnson's Government signed contracts three months after the EU and the UK was struggling as a result then would it be Anglophobia to point that out?
    Just mimicking OP's equally 'arguable' use of the word. And yes, I'm afraid this is tickling up the europhobia of europhobes something rotten.

    But anyway, thanks for the contribution. I maintain a list of your specialisms - you know how I am with lists - and I will now add 'big ticket pharma contracts' to it.
  • MarqueeMarkMarqueeMark Posts: 52,600

    England only vaccination data out

    1st dose 2nd dose
    Total 259306 1001
    East Of England 29244 47
    London 43555 445
    Midlands 41813 131
    North East And Yorkshire 38513 56
    North West 35271 95
    South East 39181 177
    South West 29908 47

    Clearly vaccine supply shortage hitting home. Time to go full Cartman on Pfizer and AZN.
    That is a weekend rate - on a weekday? Hmmmm.
  • HYUFDHYUFD Posts: 123,127
    eek said:

    HYUFD said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Leavers still getting what they voted for though.

    Leave the EU tick, end free movement tick, keep Nissan in Sunderland tick, reduce the influence of the City of London tick
    So you are happy that the biggest source of tax revenue is screwed due to decisions Boris made last year see

    https://twitter.com/nicktolhurst/status/1354419288313126923
    I voted Remain, however as I said Leavers got what they voted for
  • TOPPING said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Yes it is significant.

    @MarqueeMark will fill you in on the details.
    This is what my conference call was about.

    We are more f*cked than a stepmom on Pornhub when our 18 month clearing exemption ends and it isn't permanently renewed.

    But those of us in the financial services sector we rank lower than fish.
    Other than a hostile act of petty vengeance what reason would tbe EU have to give clearing equivalence to US but not UK?
    Because the US companies have agreed to stick to the EU rules, whilst we want to ignore them. The EU position is if you want equivalency you have to stick to our rules, the US says fine, the UK less so.

    Honestly, 'liquidation periods' and 'anti procyclicality measure' is all the rage.
  • eekeek Posts: 28,398
    TOPPING said:

    TOPPING said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Yes it is significant.

    @MarqueeMark will fill you in on the details.
    This is what my conference call was about.

    We are more f*cked than a stepmom on Pornhub when our 18 month clearing exemption ends and it isn't permanently renewed.

    But those of us in the financial services sector we rank lower than fish.
    Other than a hostile act of petty vengeance what reason would tbe EU have to give clearing equivalence to US but not UK?
    Because we haven't been negotiating for it?
    Yep - as I just posted - Boris didn't ask for it because of "sovereignty" and clearly either no-one bothered to tell him of the importance or he didn't understand the importance.

    I'm not sure which of the too options are worse for the Government.
  • YBarddCwscYBarddCwsc Posts: 7,172

    WOW ... wonderful tool. :)

    And what a performance by the City of Cambridge ... the smallest excess in E,W & S.

    No statistically significant excess deaths from COVID. In a City of 123k. Top of the Class.
    Doesn't that just point out the limitation of the tool at this granular level?

    If you look at the figures, 71 people in Cambridge died with COVID. The figure in similarly sized Norwich is 49. Yet Norwich is shown with a reasonably substantial 19% excess death rate whereas Cambridge, where to reiterate MORE people have died with COVID, is shown as having no excess deaths.

    So what's happening here? Are Cambridge recording deaths in a very different way? Is Norwich having a whole load of people dying of COVID without any diagnosis? It seems more likely that Norwich has had a fairly low death rate in the period before COVID for whatever reason, and Cambridge a fairly high one. It also seems as if it probably isn't sensible to do this on a local authority level as it reflects more random variance in the numbers when looking at quite small samples, rather than some kind of story of success in Cambridge and failure in Norwich.
    In details, I don't know the answer to your question, as I didn't construct the tool. However, the deaths in Cambridge
    City have been very, very, very low.

    Do deaths in the huge Addenbrooke's Hospital, Cambridge get recored as "in Cambridge" despite the fact that the patient may have come from outside Cambridge city? Maybe they are included in the first figure ("71 deaths in Cambridge"), but not in the second ?

    Overall, the picture in the map makes a lot of sense, so I don't agree that the tool is limited because of its granularity.
  • Casino_RoyaleCasino_Royale Posts: 60,487
    geoffw said:

    Does London have that? Are they going for the coveted time-zone?
    Not a coincidence.

    Give us the vaccine, or we'll f**k your banks.
  • TOPPING said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Yes it is significant.

    @MarqueeMark will fill you in on the details.
    This is what my conference call was about.

    We are more f*cked than a stepmom on Pornhub when our 18 month clearing exemption ends and it isn't permanently renewed.

    But those of us in the financial services sector we rank lower than fish.
    Other than a hostile act of petty vengeance what reason would tbe EU have to give clearing equivalence to US but not UK?
    It's not petty vengeance, it's hard-headed commercial calculation, combined with an understandable wish to have direct regulatory oversight over the trading. They want the European timezone trading to move to their exchanges. Why shouldn't they? They don't owe the City or the UK any favours, it was entirely our decision to leave the Single Market and also entirely the decision of Boris not to bother even trying to include services in his thin trade deal.
  • GallowgateGallowgate Posts: 19,468
    HYUFD said:

    eek said:

    HYUFD said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Leavers still getting what they voted for though.

    Leave the EU tick, end free movement tick, keep Nissan in Sunderland tick, reduce the influence of the City of London tick
    So you are happy that the biggest source of tax revenue is screwed due to decisions Boris made last year see

    https://twitter.com/nicktolhurst/status/1354419288313126923
    I voted Remain, however as I said Leavers got what they voted for
    No they haven't. If they get given swinging cuts in response to falling tax revenues. No leaver voted for cuts. They voted for increased spending. On them.
  • TOPPING said:

    kinabalu said:

    RobD said:

    kinabalu said:

    RobD said:

    kinabalu said:

    ydoethur said:

    ydoethur said:

    eek said:

    Nigelb said:


    It would only be interesting, indeed astonishing, if such caveats weren't in the contract.

    It is completely inconceivable that the contract wouldn't include lots of such caveats. There is absolutely no way AZ would have given a firm commitment on delivery dates for a brand-new vaccine, involving new production facilities and dependent on other suppliers who themselves were also doing things for the first time, all in a super-fast timescale.
    As AZ CEO has continually stated the contract is based on best endeavors.

    I'm actually surprised how polite he is being in public considering the games the EU seem to be playing.
    https://twitter.com/danielboffey/status/1354401225995911169?s=20
    I don't know what the EU think they're playing at. They really are in a negotiation where AZ hold all the cards. After all, if the EU get too bolshie AZ have the option to simply walk away from the contract, close their European factory and concentrate on other markets.

    And there is exactly feck all the EU can do about it.

    So the 'win' here for the EU is they accept a lower delivery than they want, and the lose is that they get none at all.
    Wrong. The EU is one of the largest markets for pharmaceuticals in the world. That gives them a lot of muscle. AZ will not want to antagonise them more than necessary, so no, AZ do not hold all the cards, far from it.
    So - just to be clear - the EU might ban AZ from operating in the EU altogether if they decide to abrogate a contract?

    Which would cause no medicine shortages of any kind, I trust?

    The EU are behaving like complete fools. It's like watching the DUP over Theresa May's deal - only worse, because you expect the DUP to behave like idiots.
    The EU feels that AZ have legged them over. So they are making a fuss.
    A resolution will be found that puts the EU in a better position than if they had not made a fuss.
    This is what I predict. Bet I'm right.
    At the detriment to who?
    I fear it might be you, Rob. But let's hope not.
    It was a legitimate question. The EU are seeking to divert supplies rightfully destined for the UK.
    Not really. That's a simplistic and jaundiced view. They are "rightfully" seeking to reduce their shortfall. In general, with fixed vaccine supply, every shot someone has means somebody else did not have it. Why are we diverting jabs from Italy? Why is Israel diverting jabs from us? Etc. It all depends on the contracts, the money, the moral view, the WHO, the balance of power, the politics etc etc. Bottom line is as I summarized and people should stop sanctimoniously moaning unless and until something that warrants it occurs. Which it hasn't yet. All that's happening is a frenzy of europhobes mutually wanking each other off and wallowing in europhobia. I'm finding it infantile and tedious.
    "Rightfully"?

    The EU signed their contracts three months late. It isn't europhobia to point this out.

    Had Johnson's Government signed contracts three months after the EU and the UK was struggling as a result then would it be Anglophobia to point that out?
    Good point. Can you please share that link again to the contract (did someone quote an extract upthread?).

    Thanks.
    https://www.repubblica.it/cronaca/2021/01/26/news/interview_pascal_soriot_ceo_astrazeneca_coronavirus_covid_vaccines-284349628/

    You said that the UK signed the AZ vaccine contract three months before EU, so you had more time to tweak and fix the potential disruptions of the supply. Why then did you commit to similar contracts with the EU, if you knew that in a very short time there could be problems like the one the EU supply chain is experiencing right now?
    "First of all, we have different plants and they have different yields and different productivity. One of the plans with the highest yield is in the UK because it started earlier. It also had its own issues, but we solved all, it has a good productivity, but it's the UK plant because it started earlier. Anyway, we didn't commit with the EU, by the way. It's not a commitment we have to Europe: it’s a best effort, we said we are going to make our best effort. The reason why we said that is because Europe at the time wanted to be supplied more or less at the same time as the UK, even though the contract was signed three months later. So we said, “ok, we're going to do our best, we’re going to try, but we cannot commit contractually because we are three months behind UK”. We knew it was a super stretch goal and we know it's a big issue, this pandemic. But our contract is not a contractual commitment. It's a best effort. Basically we said we're going to try our best, but we can't guarantee we're going to succeed. In fact, getting there, we are a little bit delayed”.

    Oops. 🤦🏻‍♂️
  • There is huge focus on deviating from the Pfizer protocol, but aren't the majority of people getting the AZN vaccine? The talk was of 5m doses of Pfizer, 20m of AZN being in the current pipeline.

    Any direct comparison to Israel is a bit flawed because they are only using Pfizer, which appear in PIII trials to give a higher level of protection after one or two doses.

    At our vaccination last saturday all 1,000 vaccinations were Pfizer
  • TOPPINGTOPPING Posts: 42,992
    eek said:

    HYUFD said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Leavers still getting what they voted for though.

    Leave the EU tick, end free movement tick, keep Nissan in Sunderland tick, reduce the influence of the City of London tick
    So you are happy that the biggest source of tax revenue is screwed due to decisions Boris made last year see

    https://twitter.com/nicktolhurst/status/1354419288313126923
    @HYUFD is not happy he is a remainer. I'm sure @Philip_Thompson and @BluestBlue are happy though.

    Not that they understand one end of it all.

    But sovereignty. And perhaps they can ring up Sleepy Joe and explain to him how his banks and the US are losing it with this deal.

  • eekeek Posts: 28,398

    geoffw said:

    Does London have that? Are they going for the coveted time-zone?
    Not a coincidence.

    Give us the vaccine, or we'll f**k your banks.
    Nope they are going to f**K our banks anyway because Boris or someone else missed the issue
  • contrariancontrarian Posts: 5,818

    geoffw said:

    Does London have that? Are they going for the coveted time-zone?
    Not a coincidence.

    Give us the vaccine, or we'll f**k your banks.
    The fury at the way the UK has so graphically exposed the EU's weaknesses over vaccines really is palpable.
  • MattWMattW Posts: 23,244
    RobD said:

    They are utterly deluded

    Nor does Brussels understand Soriot's argument that the British government had ordered the vaccines earlier. The contract does not speak of the principle of "first come, first served".
    I wonder which legal system this is under?
  • eek said:

    TOPPING said:

    TOPPING said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Yes it is significant.

    @MarqueeMark will fill you in on the details.
    This is what my conference call was about.

    We are more f*cked than a stepmom on Pornhub when our 18 month clearing exemption ends and it isn't permanently renewed.

    But those of us in the financial services sector we rank lower than fish.
    Other than a hostile act of petty vengeance what reason would tbe EU have to give clearing equivalence to US but not UK?
    Because we haven't been negotiating for it?
    Yep - as I just posted - Boris didn't ask for it because of "sovereignty" and clearly either no-one bothered to tell him of the importance or he didn't understand the importance.

    I'm not sure which of the too options are worse for the Government.
    Third option- people tried to tell him, but he drowned them out by singing Patriotic Songs? (Or less absurdly, he knew, understood and decided he didn't care?)
  • YBarddCwscYBarddCwsc Posts: 7,172


    It is quite possible -- if the EU continue to behave like this -- that it magnifies Boris' "success".

    Is CCHQ advIsing the EU ?

    Because i really cannot think of much that could help Boris more than the EU over-reacting and blocking vaccine exports.

    It simultaneously focuses voters' attention on Boris' one big success in the COVID pandemic, as well as one big advantage of Brexit.

    And by over-reacting, the EU look like a mobster state.

    Why does the EU give a damn how this makes Boris Johnson look? It's a very Anglocentric view of things.

    The point is WE give a damn. This is a betting site, and there are elections coming up.

    This is politicalbetting.com, not remainerwanking.com.

    (And don't ever call me ANGLOcentric, again).
  • MysticroseMysticrose Posts: 4,688
    Can anyone explain to me how Bloomberg are getting their UK stats? They are always ahead of the UK official figures and this morning, for instance, are reporting the UK figure as 7,325,775 which would be an increase of 475,000 in 24 hours. Is this accurate?

    https://www.bloomberg.com/graphics/covid-vaccine-tracker-global-distribution/

  • FoxyFoxy Posts: 48,713

    Foxy said:

    Foxy said:

    RobD said:

    Foxy said:

    Best performing countries for Covid vaccine doses given out:

    Israel (9.05 million) 47.90 per 100 population
    UAE (9.77 million) 27.107 per 100 population
    United Kingdom (67 million) 10.79 per 100 population

    ...

    European Union (446 million) 2.11 per 100 population

    Still @Nigel_Foremain reckons "big" "muscle" works when it comes to pharmaceuticals. "Big" doesn't work. "Muscle" doesn't work.

    Small countries nimbly looking after themselves works.

    Bear in mind, that % covers the entire population. But 21% of the UK population is under 18. So, as we have no plans to vaccinate Da Yoof yet, we have actually jabbed 10.79m of the total 53m pool - we have done over 20% of the adult population of the UK.

    And we have probably jabbed a million more by now - so we are at 22.5% as of this moment.
    Half-jabbed...
    Which we are repeatedly told confer the majority of the protection.
    Yes, we are repeatedly told that in the UK. A wing and a prayer springs to mind.
    C'mon, you're not subscribing to that BMA nonsense are you? There's MASSIVE evidence around the world that the first jab, certainly of the Pfizer/BioNTech vaccine, provides a very high degree of protection, both in the published clinical trial data and in the real-world experience coming out of Israel. For the AZ vaccine, the boss himself confirmed the same yesterday.
    As I said, it may be a gamble that comes off, but it is a gamble.

    Israel is sticking to the protocol, so we have to wait until March to see if our different protocol works.
    Isn't sticking to three weeks a gamble on the other side of the bet though? You are precluding people from Jab 1 to give others Jab 2.

    That's a gamble in and of itself.
    You would be following the science, not gambling on anticipating it.

    Gambles often come off, but gamblers should know there is no such thing as a sure thing.

  • HYUFDHYUFD Posts: 123,127

    HYUFD said:

    eek said:

    HYUFD said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Leavers still getting what they voted for though.

    Leave the EU tick, end free movement tick, keep Nissan in Sunderland tick, reduce the influence of the City of London tick
    So you are happy that the biggest source of tax revenue is screwed due to decisions Boris made last year see

    https://twitter.com/nicktolhurst/status/1354419288313126923
    I voted Remain, however as I said Leavers got what they voted for
    No they haven't. If they get given swinging cuts in response to falling tax revenues. No leaver voted for cuts. They voted for increased spending. On them.
    Spending as a percentage of gdp has also increased substantially since the austerity of the Cameron-Clegg-Osborne coalition years too
  • TheScreamingEaglesTheScreamingEagles Posts: 119,666
    edited January 2021
    TOPPING said:

    TOPPING said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Yes it is significant.

    @MarqueeMark will fill you in on the details.
    This is what my conference call was about.

    We are more f*cked than a stepmom on Pornhub when our 18 month clearing exemption ends and it isn't permanently renewed.

    But those of us in the financial services sector we rank lower than fish.
    It's quite amazing really. We had better hope for equivalence.
    One of the chaps who is really impacted by this was a heavy backer of Brexit.

    He is wistfully saying if you wanted to wilfully destroy the City of London/the UK's financial services pre-eminence then it would look a lot like Boris Johnson's Brexit deal.

    There's a side betting market going on here, when will 'anti big bang' day happen, I'm going for the 4th of July 2022, plenty of people have gone for much earlier.
  • AnabobazinaAnabobazina Posts: 23,486

    England only vaccination data out

    1st dose 2nd dose
    Total 259306 1001
    East Of England 29244 47
    London 43555 445
    Midlands 41813 131
    North East And Yorkshire 38513 56
    North West 35271 95
    South East 39181 177
    South West 29908 47

    Clearly vaccine supply shortage hitting home. Time to go full Cartman on Pfizer and AZN.
    That is behind the required rate by a good chalk.

    Very worrying.
  • Andy_JSAndy_JS Posts: 32,588
    edited January 2021

    Can anyone explain to me how Bloomberg are getting their UK stats? They are always ahead of the UK official figures and this morning, for instance, are reporting the UK figure as 7,325,775 which would be an increase of 475,000 in 24 hours. Is this accurate?

    https://www.bloomberg.com/graphics/covid-vaccine-tracker-global-distribution/

    That number is the same type of increase that has been happening for the last 5 or 6 days so it sounds accurate. For example both Saturday and Friday's number of jabs were around 480,000.
  • PulpstarPulpstar Posts: 78,204
    edited January 2021
    Foxy said:

    Foxy said:

    Foxy said:

    RobD said:

    Foxy said:

    Best performing countries for Covid vaccine doses given out:

    Israel (9.05 million) 47.90 per 100 population
    UAE (9.77 million) 27.107 per 100 population
    United Kingdom (67 million) 10.79 per 100 population

    ...

    European Union (446 million) 2.11 per 100 population

    Still @Nigel_Foremain reckons "big" "muscle" works when it comes to pharmaceuticals. "Big" doesn't work. "Muscle" doesn't work.

    Small countries nimbly looking after themselves works.

    Bear in mind, that % covers the entire population. But 21% of the UK population is under 18. So, as we have no plans to vaccinate Da Yoof yet, we have actually jabbed 10.79m of the total 53m pool - we have done over 20% of the adult population of the UK.

    And we have probably jabbed a million more by now - so we are at 22.5% as of this moment.
    Half-jabbed...
    Which we are repeatedly told confer the majority of the protection.
    Yes, we are repeatedly told that in the UK. A wing and a prayer springs to mind.
    C'mon, you're not subscribing to that BMA nonsense are you? There's MASSIVE evidence around the world that the first jab, certainly of the Pfizer/BioNTech vaccine, provides a very high degree of protection, both in the published clinical trial data and in the real-world experience coming out of Israel. For the AZ vaccine, the boss himself confirmed the same yesterday.
    As I said, it may be a gamble that comes off, but it is a gamble.

    Israel is sticking to the protocol, so we have to wait until March to see if our different protocol works.
    Isn't sticking to three weeks a gamble on the other side of the bet though? You are precluding people from Jab 1 to give others Jab 2.

    That's a gamble in and of itself.
    You would be following the science, not gambling on anticipating it.

    Gambles often come off, but gamblers should know there is no such thing as a sure thing.

    If the 90% figure is correct, the delayed strategy is entirely justified. I come at this from the angle of someone who would have not done things the UK way.
  • MysticroseMysticrose Posts: 4,688
    edited January 2021
    The EU are clearly in a mess and are lashing out at AZ. They're blaming the pharmaceuticals for supply problems which really stem back to their own over-centralised bureaucracy.
  • IanB2IanB2 Posts: 49,868
    Cambridge Union (online) debate, tomorrow evening:

    This House believes lockdown was a mistake

    For: Tice, Brady, Toby Y
    Against: Moran, Spinney, Whitaker

    Should be streamed on YouTube

  • It is quite possible -- if the EU continue to behave like this -- that it magnifies Boris' "success".

    Is CCHQ advIsing the EU ?

    Because i really cannot think of much that could help Boris more than the EU over-reacting and blocking vaccine exports.

    It simultaneously focuses voters' attention on Boris' one big success in the COVID pandemic, as well as one big advantage of Brexit.

    And by over-reacting, the EU look like a mobster state.

    It's really amazing - the EU couldn't be doing a better job for Boris and the Government if they'd been hired to do PR at a million pounds a day. You can't buy this kind of coverage.

    A very generous gesture from our continental cousins :wink:
    Why would the EU give a flying fuck what our voters think of their actions or whether Boris benefits from them or not? Its obligations are to its members, and we are no longer members. We have left the EU. It is strange how long this seems to be taking to sink in with some people!
  • CarlottaVanceCarlottaVance Posts: 60,216

    England only vaccination data out

    1st dose 2nd dose
    Total 259306 1001
    East Of England 29244 47
    London 43555 445
    Midlands 41813 131
    North East And Yorkshire 38513 56
    North West 35271 95
    South East 39181 177
    South West 29908 47

    Bit disappointing while its up 10% vs yesterday its down vs 1 week ago:

    Total: 260,307 -41,055
    First: 259,306 -39,067
    Second: 1,001 -1,988
  • dixiedeandixiedean Posts: 29,410

    TOPPING said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Yes it is significant.

    @MarqueeMark will fill you in on the details.
    This is what my conference call was about.

    We are more f*cked than a stepmom on Pornhub when our 18 month clearing exemption ends and it isn't permanently renewed.

    But those of us in the financial services sector we rank lower than fish.
    Bottom feeders.
  • FrancisUrquhartFrancisUrquhart Posts: 82,092
    edited January 2021

    Can anyone explain to me how Bloomberg are getting their UK stats? They are always ahead of the UK official figures and this morning, for instance, are reporting the UK figure as 7,325,775 which would be an increase of 475,000 in 24 hours. Is this accurate?

    https://www.bloomberg.com/graphics/covid-vaccine-tracker-global-distribution/

    That 7 million figure looks like yesterdays total 1st + 2nd jab figure from the official UK stats site.

    Why not just stick to the official UK, England, Wales erc sites?
  • MattWMattW Posts: 23,244
    RobD said:

    kinabalu said:

    RobD said:

    kinabalu said:

    RobD said:

    kinabalu said:

    ydoethur said:

    ydoethur said:

    eek said:

    Nigelb said:


    It would only be interesting, indeed astonishing, if such caveats weren't in the contract.

    It is completely inconceivable that the contract wouldn't include lots of such caveats. There is absolutely no way AZ would have given a firm commitment on delivery dates for a brand-new vaccine, involving new production facilities and dependent on other suppliers who themselves were also doing things for the first time, all in a super-fast timescale.
    As AZ CEO has continually stated the contract is based on best endeavors.

    I'm actually surprised how polite he is being in public considering the games the EU seem to be playing.
    https://twitter.com/danielboffey/status/1354401225995911169?s=20
    I don't know what the EU think they're playing at. They really are in a negotiation where AZ hold all the cards. After all, if the EU get too bolshie AZ have the option to simply walk away from the contract, close their European factory and concentrate on other markets.

    And there is exactly feck all the EU can do about it.

    So the 'win' here for the EU is they accept a lower delivery than they want, and the lose is that they get none at all.
    Wrong. The EU is one of the largest markets for pharmaceuticals in the world. That gives them a lot of muscle. AZ will not want to antagonise them more than necessary, so no, AZ do not hold all the cards, far from it.
    So - just to be clear - the EU might ban AZ from operating in the EU altogether if they decide to abrogate a contract?

    Which would cause no medicine shortages of any kind, I trust?

    The EU are behaving like complete fools. It's like watching the DUP over Theresa May's deal - only worse, because you expect the DUP to behave like idiots.
    The EU feels that AZ have legged them over. So they are making a fuss.
    A resolution will be found that puts the EU in a better position than if they had not made a fuss.
    This is what I predict. Bet I'm right.
    At the detriment to who?
    I fear it might be you, Rob. But let's hope not.
    It was a legitimate question. The EU are seeking to divert supplies rightfully destined for the UK.
    Not really. That's a simplistic and jaundiced view. They are "rightfully" seeking to reduce their shortfall. In general, with fixed vaccine supply, every shot someone has means somebody else did not have it. Why are we diverting jabs from Italy? Why is Israel diverting jabs from us? Etc. It all depends on the contracts, the money, the moral view, the WHO, the balance of power, the politics etc etc. Bottom line is as I summarized and people should stop sanctimoniously moaning unless and until something that warrants it occurs. Which it hasn't yet. All that's happening is a frenzy of europhobes mutually wanking each other off and wallowing in europhobia. I'm finding it infantile and tedious.
    The EU are trying to bully their way into more vaccines because they've completely buggered vaccine procurement and roll-out. They might have a point if they weren't three months behind the UK, and invested more than 1/7th of the UK and US totals.
    If they are a consistent 3 months behind, this still has a month to run.

    Will be ... interesting.
  • BurgessianBurgessian Posts: 2,752
    Re - the earlier George Galloway posts, the wheels seem to have come off his most recent political venture, at least for the time being:

    https://www.dailyrecord.co.uk/news/scottish-news/george-galloways-application-new-party-23390859

    Shame. He adds to the gaiety of nations.
  • TOPPINGTOPPING Posts: 42,992

    TOPPING said:

    kinabalu said:

    RobD said:

    kinabalu said:

    RobD said:

    kinabalu said:

    ydoethur said:

    ydoethur said:

    eek said:

    Nigelb said:


    It would only be interesting, indeed astonishing, if such caveats weren't in the contract.

    It is completely inconceivable that the contract wouldn't include lots of such caveats. There is absolutely no way AZ would have given a firm commitment on delivery dates for a brand-new vaccine, involving new production facilities and dependent on other suppliers who themselves were also doing things for the first time, all in a super-fast timescale.
    As AZ CEO has continually stated the contract is based on best endeavors.

    I'm actually surprised how polite he is being in public considering the games the EU seem to be playing.
    https://twitter.com/danielboffey/status/1354401225995911169?s=20
    I don't know what the EU think they're playing at. They really are in a negotiation where AZ hold all the cards. After all, if the EU get too bolshie AZ have the option to simply walk away from the contract, close their European factory and concentrate on other markets.

    And there is exactly feck all the EU can do about it.

    So the 'win' here for the EU is they accept a lower delivery than they want, and the lose is that they get none at all.
    Wrong. The EU is one of the largest markets for pharmaceuticals in the world. That gives them a lot of muscle. AZ will not want to antagonise them more than necessary, so no, AZ do not hold all the cards, far from it.
    So - just to be clear - the EU might ban AZ from operating in the EU altogether if they decide to abrogate a contract?

    Which would cause no medicine shortages of any kind, I trust?

    The EU are behaving like complete fools. It's like watching the DUP over Theresa May's deal - only worse, because you expect the DUP to behave like idiots.
    The EU feels that AZ have legged them over. So they are making a fuss.
    A resolution will be found that puts the EU in a better position than if they had not made a fuss.
    This is what I predict. Bet I'm right.
    At the detriment to who?
    I fear it might be you, Rob. But let's hope not.
    It was a legitimate question. The EU are seeking to divert supplies rightfully destined for the UK.
    Not really. That's a simplistic and jaundiced view. They are "rightfully" seeking to reduce their shortfall. In general, with fixed vaccine supply, every shot someone has means somebody else did not have it. Why are we diverting jabs from Italy? Why is Israel diverting jabs from us? Etc. It all depends on the contracts, the money, the moral view, the WHO, the balance of power, the politics etc etc. Bottom line is as I summarized and people should stop sanctimoniously moaning unless and until something that warrants it occurs. Which it hasn't yet. All that's happening is a frenzy of europhobes mutually wanking each other off and wallowing in europhobia. I'm finding it infantile and tedious.
    "Rightfully"?

    The EU signed their contracts three months late. It isn't europhobia to point this out.

    Had Johnson's Government signed contracts three months after the EU and the UK was struggling as a result then would it be Anglophobia to point that out?
    Good point. Can you please share that link again to the contract (did someone quote an extract upthread?).

    Thanks.
    https://www.repubblica.it/cronaca/2021/01/26/news/interview_pascal_soriot_ceo_astrazeneca_coronavirus_covid_vaccines-284349628/

    You said that the UK signed the AZ vaccine contract three months before EU, so you had more time to tweak and fix the potential disruptions of the supply. Why then did you commit to similar contracts with the EU, if you knew that in a very short time there could be problems like the one the EU supply chain is experiencing right now?
    "First of all, we have different plants and they have different yields and different productivity. One of the plans with the highest yield is in the UK because it started earlier. It also had its own issues, but we solved all, it has a good productivity, but it's the UK plant because it started earlier. Anyway, we didn't commit with the EU, by the way. It's not a commitment we have to Europe: it’s a best effort, we said we are going to make our best effort. The reason why we said that is because Europe at the time wanted to be supplied more or less at the same time as the UK, even though the contract was signed three months later. So we said, “ok, we're going to do our best, we’re going to try, but we cannot commit contractually because we are three months behind UK”. We knew it was a super stretch goal and we know it's a big issue, this pandemic. But our contract is not a contractual commitment. It's a best effort. Basically we said we're going to try our best, but we can't guarantee we're going to succeed. In fact, getting there, we are a little bit delayed”.

    Oops. 🤦🏻‍♂️
    Thanks has the contract been released?
  • eekeek Posts: 28,398
    TOPPING said:

    eek said:

    HYUFD said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Leavers still getting what they voted for though.

    Leave the EU tick, end free movement tick, keep Nissan in Sunderland tick, reduce the influence of the City of London tick
    So you are happy that the biggest source of tax revenue is screwed due to decisions Boris made last year see

    https://twitter.com/nicktolhurst/status/1354419288313126923
    @HYUFD is not happy he is a remainer. I'm sure @Philip_Thompson and @BluestBlue are happy though.

    Not that they understand one end of it all.

    But sovereignty. And perhaps they can ring up Sleepy Joe and explain to him how his banks and the US are losing it with this deal.

    The US aren't losing anything except for the poor sods who will be working the European Hours shifts on the East Coast.
  • dixiedean said:

    TOPPING said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Yes it is significant.

    @MarqueeMark will fill you in on the details.
    This is what my conference call was about.

    We are more f*cked than a stepmom on Pornhub when our 18 month clearing exemption ends and it isn't permanently renewed.

    But those of us in the financial services sector we rank lower than fish.
    Bottom feeders.
    But the country realise we're better than Boris Johnson.

    Boris Johnson is just pissed that he ranks much lower than us.

    https://twitter.com/MattChorley/status/1353991515677339648
  • TOPPINGTOPPING Posts: 42,992

    TOPPING said:

    TOPPING said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Yes it is significant.

    @MarqueeMark will fill you in on the details.
    This is what my conference call was about.

    We are more f*cked than a stepmom on Pornhub when our 18 month clearing exemption ends and it isn't permanently renewed.

    But those of us in the financial services sector we rank lower than fish.
    Other than a hostile act of petty vengeance what reason would tbe EU have to give clearing equivalence to US but not UK?
    Because we haven't been negotiating for it?
    Fish >> Finance remember.
    I wouldn't mind but we didn't even win on the fish.
  • Richard_NabaviRichard_Nabavi Posts: 30,821
    edited January 2021
    The irony is that the EU were expecting us to ask for something on financial services in return for not shafting the EU fishing industry. They were amazed that we didn't bother with the first bit, and then we went on to shaft the UK fishing industry instead.
  • dixiedeandixiedean Posts: 29,410
    HYUFD said:
    Crumbs Ted. There are 81 million in those 3 categories?
    America has changed since I was last there.
  • eekeek Posts: 28,398

    England only vaccination data out

    1st dose 2nd dose
    Total 259306 1001
    East Of England 29244 47
    London 43555 445
    Midlands 41813 131
    North East And Yorkshire 38513 56
    North West 35271 95
    South East 39181 177
    South West 29908 47

    Clearly vaccine supply shortage hitting home. Time to go full Cartman on Pfizer and AZN.
    That is behind the required rate by a good chalk.

    Very worrying.
    This was already mentioned last week - there is a short term shortfall due to ramping up issues.
  • Foxy said:

    Foxy said:

    RobD said:

    Foxy said:

    Best performing countries for Covid vaccine doses given out:

    Israel (9.05 million) 47.90 per 100 population
    UAE (9.77 million) 27.107 per 100 population
    United Kingdom (67 million) 10.79 per 100 population

    ...

    European Union (446 million) 2.11 per 100 population

    Still @Nigel_Foremain reckons "big" "muscle" works when it comes to pharmaceuticals. "Big" doesn't work. "Muscle" doesn't work.

    Small countries nimbly looking after themselves works.

    Bear in mind, that % covers the entire population. But 21% of the UK population is under 18. So, as we have no plans to vaccinate Da Yoof yet, we have actually jabbed 10.79m of the total 53m pool - we have done over 20% of the adult population of the UK.

    And we have probably jabbed a million more by now - so we are at 22.5% as of this moment.
    Half-jabbed...
    Which we are repeatedly told confer the majority of the protection.
    Yes, we are repeatedly told that in the UK. A wing and a prayer springs to mind.
    C'mon, you're not subscribing to that BMA nonsense are you? There's MASSIVE evidence around the world that the first jab, certainly of the Pfizer/BioNTech vaccine, provides a very high degree of protection, both in the published clinical trial data and in the real-world experience coming out of Israel. For the AZ vaccine, the boss himself confirmed the same yesterday.
    As I said, it may be a gamble that comes off, but it is a gamble.

    Israel is sticking to the protocol, so we have to wait until March to see if our different protocol works.
    Nate Silver makes the correct point that it's just Bayesian versus frequentist statistics. Bayesian stats does have a "gambling" feel to it in that it assigns a prior probability to a hypothesis. But it's probably the better approach to the problem in this case - frequentist caution makes you feel better because you've followed the recipe, but probably doesn't have as good an expected pay-off.
  • felixfelix Posts: 15,164


    It is quite possible -- if the EU continue to behave like this -- that it magnifies Boris' "success".

    Is CCHQ advIsing the EU ?

    Because i really cannot think of much that could help Boris more than the EU over-reacting and blocking vaccine exports.

    It simultaneously focuses voters' attention on Boris' one big success in the COVID pandemic, as well as one big advantage of Brexit.

    And by over-reacting, the EU look like a mobster state.

    Why does the EU give a damn how this makes Boris Johnson look? It's a very Anglocentric view of things.

    The EU presumably see it as key to look to people in the EU as if they are playing hardball with a pharma company who have fallen short of their contractual obligations, and in fact to squeeze as much vaccine out of AZ as possible. If that also distracts British citizens from the massive death rate in the UK, and benefits Johnson, so what from their perspective?
    There is no evidence yet that AZN have fallen short of their contractual obligations.
  • ydoethurydoethur Posts: 71,421
    Anyway, I must go and teach some more, but here's a joke that's appropriate for today:

    An American and a German architect bet who can build a skyscraper in the least amount of time. After a month the American mails the German: "Only 10 days and I'll be finished."
    The German writes back: "Hah, that's nothing. Only 10 forms left and I am allowed to start."
  • PulpstarPulpstar Posts: 78,204
    edited January 2021

    England only vaccination data out

    1st dose 2nd dose
    Total 259306 1001
    East Of England 29244 47
    London 43555 445
    Midlands 41813 131
    North East And Yorkshire 38513 56
    North West 35271 95
    South East 39181 177
    South West 29908 47

    Clearly vaccine supply shortage hitting home. Time to go full Cartman on Pfizer and AZN.
    That is behind the required rate by a good chalk.

    Very worrying.
    The world won't go pop if we miss the target.

    Triple J vaccine should be with us shortly.
  • FrancisUrquhartFrancisUrquhart Posts: 82,092
    edited January 2021

    England only vaccination data out

    1st dose 2nd dose
    Total 259306 1001
    East Of England 29244 47
    London 43555 445
    Midlands 41813 131
    North East And Yorkshire 38513 56
    North West 35271 95
    South East 39181 177
    South West 29908 47

    Clearly vaccine supply shortage hitting home. Time to go full Cartman on Pfizer and AZN.
    That is behind the required rate by a good chalk.

    Very worrying.
    I said at the very start I thought government were again in danger of over promising / under delivering by relying on factors outside their control to all go perfectly. They will get loads of.blame if the target is missed, when from the capacity side of things it is all there to do 500k/day, it is all supply side.
  • EndillionEndillion Posts: 4,976
    Foxy said:

    RobD said:

    Foxy said:

    Andy_JS said:

    Psizer: first jab gives 90% protection, second gives 94% protection. You can see why they're delaying the second one.

    The difference in antibodies a week after the second injection is 10 fold.
    Israel finds single dose gives high resistance

    https://www.ft.com/content/4d9fe80d-e604-4bbe-b0f8-fd4b8df9b7f1
    And went ahead with the second dose on schedule.
    Israel didn't have a choice, and didn't have a reason to delay anyway. Their supply of the vaccine is predicated on supplying the data back to Pfizer, so they a) have the supplies they need to do the double jab as planned and b) they are required by the terms of their contract to do the jabs as and when Pfizer want them.
  • MalmesburyMalmesbury Posts: 50,361

    England only vaccination data out

    1st dose 2nd dose
    Total 259306 1001
    East Of England 29244 47
    London 43555 445
    Midlands 41813 131
    North East And Yorkshire 38513 56
    North West 35271 95
    South East 39181 177
    South West 29908 47

    Clearly vaccine supply shortage hitting home. Time to go full Cartman on Pfizer and AZN.
    That is behind the required rate by a good chalk.

    Very worrying.
    Have a look at this

    https://ourworldindata.org/coronavirus-data-explorer?zoomToSelection=true&time=2020-12-20..latest&country=~ISR&region=World&vaccinationsMetric=true&interval=daily&perCapita=true&smoothing=0&pickerMetric=total_vaccinations_per_hundred&pickerSort=desc

    That's the actual daily rates in Israel. They are all over the place, on a daily basis.

    Here is the US

    https://ourworldindata.org/coronavirus-data-explorer?zoomToSelection=true&time=2020-12-20..latest&country=~USA&region=World&vaccinationsMetric=true&interval=daily&perCapita=true&smoothing=0&pickerMetric=total_vaccinations_per_hundred&pickerSort=desc

    See a pattern developing?
  • HYUFDHYUFD Posts: 123,127
    edited January 2021

    TOPPING said:

    TOPPING said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Yes it is significant.

    @MarqueeMark will fill you in on the details.
    This is what my conference call was about.

    We are more f*cked than a stepmom on Pornhub when our 18 month clearing exemption ends and it isn't permanently renewed.

    But those of us in the financial services sector we rank lower than fish.
    It's quite amazing really. We had better hope for equivalence.
    One of the chaps who is really impacted by this was a heavy backer of Brexit.

    He is wistfully saying if you wanted to wilfully destroy the City of London/the UK's financial services pre-eminence then it would look a lot like Boris Johnson's Brexit deal.

    There's a side betting market going on here, when will 'anti big bang' day happen, I'm going for the 4th of July 2022, plenty of people have gone for much earlier.
    I think Cities of London and Westminster will be a Labour or LD gain next time, Kensington will also likely go back to Labour. The Tories could also lose West Central in the GLA elections in May.

    Even in 1997 the Tories held those seats, now they are marginals along with commuter filled seats like Esher and Walton.

    Formerly safe Labour seats like Grimsby and West Bromwich and Sedgefield and Bolsover though now have Tory MPs as the Tory Party has become more working class and less the party of financial services and the City of London
  • Daveyboy1961Daveyboy1961 Posts: 3,883

    TOPPING said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Yes it is significant.

    @MarqueeMark will fill you in on the details.
    This is what my conference call was about.

    We are more f*cked than a stepmom on Pornhub when our 18 month clearing exemption ends and it isn't permanently renewed.

    But those of us in the financial services sector we rank lower than fish.
    Congrats on a marvellous simile/metaphor, thats made my day.

    :smiley:
  • kinabalukinabalu Posts: 42,213
    RobD said:

    kinabalu said:

    RobD said:

    kinabalu said:

    RobD said:

    kinabalu said:

    ydoethur said:

    ydoethur said:

    eek said:

    Nigelb said:


    It would only be interesting, indeed astonishing, if such caveats weren't in the contract.

    It is completely inconceivable that the contract wouldn't include lots of such caveats. There is absolutely no way AZ would have given a firm commitment on delivery dates for a brand-new vaccine, involving new production facilities and dependent on other suppliers who themselves were also doing things for the first time, all in a super-fast timescale.
    As AZ CEO has continually stated the contract is based on best endeavors.

    I'm actually surprised how polite he is being in public considering the games the EU seem to be playing.
    https://twitter.com/danielboffey/status/1354401225995911169?s=20
    I don't know what the EU think they're playing at. They really are in a negotiation where AZ hold all the cards. After all, if the EU get too bolshie AZ have the option to simply walk away from the contract, close their European factory and concentrate on other markets.

    And there is exactly feck all the EU can do about it.

    So the 'win' here for the EU is they accept a lower delivery than they want, and the lose is that they get none at all.
    Wrong. The EU is one of the largest markets for pharmaceuticals in the world. That gives them a lot of muscle. AZ will not want to antagonise them more than necessary, so no, AZ do not hold all the cards, far from it.
    So - just to be clear - the EU might ban AZ from operating in the EU altogether if they decide to abrogate a contract?

    Which would cause no medicine shortages of any kind, I trust?

    The EU are behaving like complete fools. It's like watching the DUP over Theresa May's deal - only worse, because you expect the DUP to behave like idiots.
    The EU feels that AZ have legged them over. So they are making a fuss.
    A resolution will be found that puts the EU in a better position than if they had not made a fuss.
    This is what I predict. Bet I'm right.
    At the detriment to who?
    I fear it might be you, Rob. But let's hope not.
    It was a legitimate question. The EU are seeking to divert supplies rightfully destined for the UK.
    Not really. That's a simplistic and jaundiced view. They are "rightfully" seeking to reduce their shortfall. In general, with fixed vaccine supply, every shot someone has means somebody else did not have it. Why are we diverting jabs from Italy? Why is Israel diverting jabs from us? Etc. It all depends on the contracts, the money, the moral view, the WHO, the balance of power, the politics etc etc. Bottom line is as I summarized and people should stop sanctimoniously moaning unless and until something that warrants it occurs. Which it hasn't yet. All that's happening is a frenzy of europhobes mutually wanking each other off and wallowing in europhobia. I'm finding it infantile and tedious.
    The EU are trying to bully their way into more vaccines because they've completely buggered vaccine procurement and roll-out. They might have a point if they weren't three months behind the UK, and invested more than 1/7th of the UK and US totals.
    Or, having made poor decisions on vaccine which put them behind the 8 ball, they were distressed to find their position made even worse due to AZ shortfalls. They are now seeking to mitigate the damage as one might expect they would and are entitled to do. It's an "in progress" negotiation and we will see what the upshot is. If the upshot justifies outrage, then outrage is what should "rightfully" ensue.

    Prefer this.
  • TOPPING said:

    TOPPING said:

    TOPPING said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Yes it is significant.

    @MarqueeMark will fill you in on the details.
    This is what my conference call was about.

    We are more f*cked than a stepmom on Pornhub when our 18 month clearing exemption ends and it isn't permanently renewed.

    But those of us in the financial services sector we rank lower than fish.
    Other than a hostile act of petty vengeance what reason would tbe EU have to give clearing equivalence to US but not UK?
    Because we haven't been negotiating for it?
    Fish >> Finance remember.
    I wouldn't mind but we didn't even win on the fish.
    I know, but don't worry we're not important, it isn't like the banking/insurance/financial services is the largest contributor to the Exchequer.

    Oh man
  • TOPPING said:

    TOPPING said:

    kinabalu said:

    RobD said:

    kinabalu said:

    RobD said:

    kinabalu said:

    ydoethur said:

    ydoethur said:

    eek said:

    Nigelb said:


    It would only be interesting, indeed astonishing, if such caveats weren't in the contract.

    It is completely inconceivable that the contract wouldn't include lots of such caveats. There is absolutely no way AZ would have given a firm commitment on delivery dates for a brand-new vaccine, involving new production facilities and dependent on other suppliers who themselves were also doing things for the first time, all in a super-fast timescale.
    As AZ CEO has continually stated the contract is based on best endeavors.

    I'm actually surprised how polite he is being in public considering the games the EU seem to be playing.
    https://twitter.com/danielboffey/status/1354401225995911169?s=20
    I don't know what the EU think they're playing at. They really are in a negotiation where AZ hold all the cards. After all, if the EU get too bolshie AZ have the option to simply walk away from the contract, close their European factory and concentrate on other markets.

    And there is exactly feck all the EU can do about it.

    So the 'win' here for the EU is they accept a lower delivery than they want, and the lose is that they get none at all.
    Wrong. The EU is one of the largest markets for pharmaceuticals in the world. That gives them a lot of muscle. AZ will not want to antagonise them more than necessary, so no, AZ do not hold all the cards, far from it.
    So - just to be clear - the EU might ban AZ from operating in the EU altogether if they decide to abrogate a contract?

    Which would cause no medicine shortages of any kind, I trust?

    The EU are behaving like complete fools. It's like watching the DUP over Theresa May's deal - only worse, because you expect the DUP to behave like idiots.
    The EU feels that AZ have legged them over. So they are making a fuss.
    A resolution will be found that puts the EU in a better position than if they had not made a fuss.
    This is what I predict. Bet I'm right.
    At the detriment to who?
    I fear it might be you, Rob. But let's hope not.
    It was a legitimate question. The EU are seeking to divert supplies rightfully destined for the UK.
    Not really. That's a simplistic and jaundiced view. They are "rightfully" seeking to reduce their shortfall. In general, with fixed vaccine supply, every shot someone has means somebody else did not have it. Why are we diverting jabs from Italy? Why is Israel diverting jabs from us? Etc. It all depends on the contracts, the money, the moral view, the WHO, the balance of power, the politics etc etc. Bottom line is as I summarized and people should stop sanctimoniously moaning unless and until something that warrants it occurs. Which it hasn't yet. All that's happening is a frenzy of europhobes mutually wanking each other off and wallowing in europhobia. I'm finding it infantile and tedious.
    "Rightfully"?

    The EU signed their contracts three months late. It isn't europhobia to point this out.

    Had Johnson's Government signed contracts three months after the EU and the UK was struggling as a result then would it be Anglophobia to point that out?
    Good point. Can you please share that link again to the contract (did someone quote an extract upthread?).

    Thanks.
    https://www.repubblica.it/cronaca/2021/01/26/news/interview_pascal_soriot_ceo_astrazeneca_coronavirus_covid_vaccines-284349628/

    You said that the UK signed the AZ vaccine contract three months before EU, so you had more time to tweak and fix the potential disruptions of the supply. Why then did you commit to similar contracts with the EU, if you knew that in a very short time there could be problems like the one the EU supply chain is experiencing right now?
    "First of all, we have different plants and they have different yields and different productivity. One of the plans with the highest yield is in the UK because it started earlier. It also had its own issues, but we solved all, it has a good productivity, but it's the UK plant because it started earlier. Anyway, we didn't commit with the EU, by the way. It's not a commitment we have to Europe: it’s a best effort, we said we are going to make our best effort. The reason why we said that is because Europe at the time wanted to be supplied more or less at the same time as the UK, even though the contract was signed three months later. So we said, “ok, we're going to do our best, we’re going to try, but we cannot commit contractually because we are three months behind UK”. We knew it was a super stretch goal and we know it's a big issue, this pandemic. But our contract is not a contractual commitment. It's a best effort. Basically we said we're going to try our best, but we can't guarantee we're going to succeed. In fact, getting there, we are a little bit delayed”.

    Oops. 🤦🏻‍♂️
    Thanks has the contract been released?
    Why should it be? Unless you're saying the CEO is lying in saying that it was a best endeavours contract? Is that what you're claiming? 🤔
  • Worth repeating, it is thought deliveries next week will be a 1/3 down on this week....
  • YBarddCwscYBarddCwsc Posts: 7,172


    It is quite possible -- if the EU continue to behave like this -- that it magnifies Boris' "success".

    Is CCHQ advIsing the EU ?

    Because i really cannot think of much that could help Boris more than the EU over-reacting and blocking vaccine exports.

    It simultaneously focuses voters' attention on Boris' one big success in the COVID pandemic, as well as one big advantage of Brexit.

    And by over-reacting, the EU look like a mobster state.

    It's really amazing - the EU couldn't be doing a better job for Boris and the Government if they'd been hired to do PR at a million pounds a day. You can't buy this kind of coverage.

    A very generous gesture from our continental cousins :wink:
    Why would the EU give a flying fuck what our voters think of their actions or whether Boris benefits from them or not? Its obligations are to its members, and we are no longer members. We have left the EU. It is strange how long this seems to be taking to sink in with some people!
    Try reading the header on the site. It is called "politicalbetting"

    There are elections coming up. That is why people are commenting on this site about possible electoral implications of a row over vaccines.

    A big phoney Vaccine War, with Boris winning, is likely to have an effect on the results.

    FWIW, I'd like to be rid of Boris -- but if Ursula wishes to play the General Leopoldo Galtieri role, that is pretty unlikely.
  • TOPPINGTOPPING Posts: 42,992

    TOPPING said:

    TOPPING said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Yes it is significant.

    @MarqueeMark will fill you in on the details.
    This is what my conference call was about.

    We are more f*cked than a stepmom on Pornhub when our 18 month clearing exemption ends and it isn't permanently renewed.

    But those of us in the financial services sector we rank lower than fish.
    It's quite amazing really. We had better hope for equivalence.
    One of the chaps who is really impacted by this was a heavy backer of Brexit.

    He is wistfully saying if you wanted to wilfully destroy the City of London/the UK's financial services pre-eminence then it would look a lot like Boris Johnson's Brexit deal.

    There's a side betting market going on here, when will 'anti big bang' day happen, I'm going for the 4th of July 2022, plenty of people have gone for much earlier.
    You can see it that's for sure.

    I never thought Brexit would be drop on your foot bad for the UK/The City just a gradual diminution of influence and a gradual seeping away of importance. Things are moving a tad quicker than I had thought.

    As for the EU/US deal what did we think? That the EU wouldn't be looking to do trade deals with the US also? The difference seems to be, however, that they have managed to do one.
  • PulpstarPulpstar Posts: 78,204
    Sanofi switching it's capacity to produce Astra? I think is positive - will result in replacement of the GSK/Sanofi envisioned capacity feeding through the pipeline.
  • TOPPINGTOPPING Posts: 42,992
    Pulpstar said:

    Foxy said:

    Foxy said:

    Foxy said:

    RobD said:

    Foxy said:

    Best performing countries for Covid vaccine doses given out:

    Israel (9.05 million) 47.90 per 100 population
    UAE (9.77 million) 27.107 per 100 population
    United Kingdom (67 million) 10.79 per 100 population

    ...

    European Union (446 million) 2.11 per 100 population

    Still @Nigel_Foremain reckons "big" "muscle" works when it comes to pharmaceuticals. "Big" doesn't work. "Muscle" doesn't work.

    Small countries nimbly looking after themselves works.

    Bear in mind, that % covers the entire population. But 21% of the UK population is under 18. So, as we have no plans to vaccinate Da Yoof yet, we have actually jabbed 10.79m of the total 53m pool - we have done over 20% of the adult population of the UK.

    And we have probably jabbed a million more by now - so we are at 22.5% as of this moment.
    Half-jabbed...
    Which we are repeatedly told confer the majority of the protection.
    Yes, we are repeatedly told that in the UK. A wing and a prayer springs to mind.
    C'mon, you're not subscribing to that BMA nonsense are you? There's MASSIVE evidence around the world that the first jab, certainly of the Pfizer/BioNTech vaccine, provides a very high degree of protection, both in the published clinical trial data and in the real-world experience coming out of Israel. For the AZ vaccine, the boss himself confirmed the same yesterday.
    As I said, it may be a gamble that comes off, but it is a gamble.

    Israel is sticking to the protocol, so we have to wait until March to see if our different protocol works.
    Isn't sticking to three weeks a gamble on the other side of the bet though? You are precluding people from Jab 1 to give others Jab 2.

    That's a gamble in and of itself.
    You would be following the science, not gambling on anticipating it.

    Gambles often come off, but gamblers should know there is no such thing as a sure thing.

    If the 90% figure is correct, the delayed strategy is entirely justified. I come at this from the angle of someone who would have not done things the UK way.
    All people are saying, all I am saying, is that there was no trial designed specifically to determine the efficacy of a single jab although there are data from the two-jab trials which are very informative.

    As such, the manufacturers, and increasingly it seems the medico-scientists won't endorse a single jab regime.

    Because no one knows. Yes infection rates drop off as we have seen from that famous graph vs placebo, but no one knows after or between that what happens. Because it wasn't in a designed trial.
  • Its seems Drakeford has stopped storing vaccines for a rainy day as if he is some squirrel burying his nuts for winter.
  • TOPPINGTOPPING Posts: 42,992

    The EU are clearly in a mess and are lashing out at AZ. They're blaming the pharmaceuticals for supply problems which really stem back to their own over-centralised bureaucracy.

    Ah thanks finally. It appears that you have seen the contract. Could you share the link.

    I don't doubt that the EU has been the EU over this I would just like to look at the details.
  • kinabalu said:

    kinabalu said:

    RobD said:

    kinabalu said:

    RobD said:

    kinabalu said:

    ydoethur said:

    ydoethur said:

    eek said:

    Nigelb said:


    It would only be interesting, indeed astonishing, if such caveats weren't in the contract.

    It is completely inconceivable that the contract wouldn't include lots of such caveats. There is absolutely no way AZ would have given a firm commitment on delivery dates for a brand-new vaccine, involving new production facilities and dependent on other suppliers who themselves were also doing things for the first time, all in a super-fast timescale.
    As AZ CEO has continually stated the contract is based on best endeavors.

    I'm actually surprised how polite he is being in public considering the games the EU seem to be playing.
    https://twitter.com/danielboffey/status/1354401225995911169?s=20
    I don't know what the EU think they're playing at. They really are in a negotiation where AZ hold all the cards. After all, if the EU get too bolshie AZ have the option to simply walk away from the contract, close their European factory and concentrate on other markets.

    And there is exactly feck all the EU can do about it.

    So the 'win' here for the EU is they accept a lower delivery than they want, and the lose is that they get none at all.
    Wrong. The EU is one of the largest markets for pharmaceuticals in the world. That gives them a lot of muscle. AZ will not want to antagonise them more than necessary, so no, AZ do not hold all the cards, far from it.
    So - just to be clear - the EU might ban AZ from operating in the EU altogether if they decide to abrogate a contract?

    Which would cause no medicine shortages of any kind, I trust?

    The EU are behaving like complete fools. It's like watching the DUP over Theresa May's deal - only worse, because you expect the DUP to behave like idiots.
    The EU feels that AZ have legged them over. So they are making a fuss.
    A resolution will be found that puts the EU in a better position than if they had not made a fuss.
    This is what I predict. Bet I'm right.
    At the detriment to who?
    I fear it might be you, Rob. But let's hope not.
    It was a legitimate question. The EU are seeking to divert supplies rightfully destined for the UK.
    Not really. That's a simplistic and jaundiced view. They are "rightfully" seeking to reduce their shortfall. In general, with fixed vaccine supply, every shot someone has means somebody else did not have it. Why are we diverting jabs from Italy? Why is Israel diverting jabs from us? Etc. It all depends on the contracts, the money, the moral view, the WHO, the balance of power, the politics etc etc. Bottom line is as I summarized and people should stop sanctimoniously moaning unless and until something that warrants it occurs. Which it hasn't yet. All that's happening is a frenzy of europhobes mutually wanking each other off and wallowing in europhobia. I'm finding it infantile and tedious.
    "Rightfully"?

    The EU signed their contracts three months late. It isn't europhobia to point this out.

    Had Johnson's Government signed contracts three months after the EU and the UK was struggling as a result then would it be Anglophobia to point that out?
    Just mimicking OP's equally 'arguable' use of the word. And yes, I'm afraid this is tickling up the europhobia of europhobes something rotten.

    But anyway, thanks for the contribution. I maintain a list of your specialisms - you know how I am with lists - and I will now add 'big ticket pharma contracts' to it.
    If you add 'ability to read' then you can make a shorter list.

    If you bothered to read this you might not make such silly remarks about contracts and what the EU is "rightfully" trying to do.
    https://www.repubblica.it/cronaca/2021/01/26/news/interview_pascal_soriot_ceo_astrazeneca_coronavirus_covid_vaccines-284349628/

    Its amazing what you can pick up with an ability to read.
  • FrancisUrquhartFrancisUrquhart Posts: 82,092
    edited January 2021
    Pulpstar said:

    Sanofi switching it's capacity to produce Astra? I think is positive - will result in replacement of the GSK/Sanofi envisioned capacity feeding through the pipeline.

    Won't happen for a number of months though, and not up to speed for even longer.
  • FloaterFloater Posts: 14,207

    Worth repeating, it is thought deliveries next week will be a 1/3 down on this week....

    We should insist vaccines intended for the EU come to us..........
  • kinabalukinabalu Posts: 42,213
    RobD said:

    As well as lots of caveats around 'best endeavours, I bet there are two further conditions in the AZ-EU contract:

    1. 'Subject to approval by the EMA', which would be an interesting one to bring into the mix.

    2. A clause stipulating that AZ won't favour other clients over the EU. The EU might think this gives them the right to dip into our supplies, but I doubt whether a proper reading of the various contracts would support that, assuming the AZ lawyers know what they are doing (which is a very, very good assumption).

    I mean it is a bunch of half-rate politicians that couldn't make it in national politics vs. lawyers that probably charge thousands an hour.
    Von der Leyen is leagues above corporate lawyer material.
  • TOPPINGTOPPING Posts: 42,992
    edited January 2021
    eek said:

    TOPPING said:

    eek said:

    HYUFD said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Leavers still getting what they voted for though.

    Leave the EU tick, end free movement tick, keep Nissan in Sunderland tick, reduce the influence of the City of London tick
    So you are happy that the biggest source of tax revenue is screwed due to decisions Boris made last year see

    https://twitter.com/nicktolhurst/status/1354419288313126923
    @HYUFD is not happy he is a remainer. I'm sure @Philip_Thompson and @BluestBlue are happy though.

    Not that they understand one end of it all.

    But sovereignty. And perhaps they can ring up Sleepy Joe and explain to him how his banks and the US are losing it with this deal.

    The US aren't losing anything except for the poor sods who will be working the European Hours shifts on the East Coast.
    haha very true I rang someone today at 9am who is on a UK-based US trading desk and realised with horror I might have woken them up.

    Thankfully already awake.
  • kinabalu said:

    RobD said:

    As well as lots of caveats around 'best endeavours, I bet there are two further conditions in the AZ-EU contract:

    1. 'Subject to approval by the EMA', which would be an interesting one to bring into the mix.

    2. A clause stipulating that AZ won't favour other clients over the EU. The EU might think this gives them the right to dip into our supplies, but I doubt whether a proper reading of the various contracts would support that, assuming the AZ lawyers know what they are doing (which is a very, very good assumption).

    I mean it is a bunch of half-rate politicians that couldn't make it in national politics vs. lawyers that probably charge thousands an hour.
    Von der Leyen is leagues above corporate lawyer material.
    Very amusing. 😂
  • IshmaelZ said:

    IshmaelZ said:

    Having our weekly delivery from Sainsbury's later on today, only have a few substitutions (Cod fillets instead of cod loins, different type of yoghurt from what was ordered,)

    The issue is not being able to order things in the first place, no courgettes, avocado, and aubergines, that sort of thing.

    Prices have gone up quite a few things.

    You need to shop at a more competent supermarket, avocados are in plentiful supply at Waitrose and I am sure courgettes and aubergines were on the shelves. The avocado I'm having for lunch comes from Colombia so presumably unaffected by Brexit
    We ordered a supplementary shop from Waitrose a fortnight ago, no courgettes, aubergines, or avocados arrived.
    I've never been that fortunate. One person in our house enjoys all three of these. It isn't me!
    Didn't James Bond once eat an avocado pear as a dessert because Ian Fleming had only heard about these exotic fruit second hand?
    He had been living partly in Jamaica for 7 years before writing the first novel, so it seems incredibly unlikely.
    Hmm. Maybe it was someone else. I might need to spend the rest of the week leafing through old books.
    http://jamesbondmemes.blogspot.com/2013/04/james-bond-introduces-avocado-pear.html
    Golly, never knew M&S did food in 1959, I thought it was something they branched into in the 80s.
    The T in my BLT yesterday hailed from Belgium. If the poor little Belgians can produce fresh tomatoes in January why not farmer Giles? I assume the vital ingredient is LPG, though it isn't mentioned on the packet.
    They've got some greenhouses

    I am getting a large box of English tomatoes delivered weekly from The Tomato Stall based on the Isle of Wight. Greenhouse grown and absolutely fresh as you could wish ever week of the year.
  • AlistairAlistair Posts: 23,670
    wallstreetbets fucking up Citron (the hedge fund not the car company) is absolutely glorious.
  • TOPPING said:

    Pulpstar said:

    Foxy said:

    Foxy said:

    Foxy said:

    RobD said:

    Foxy said:

    Best performing countries for Covid vaccine doses given out:

    Israel (9.05 million) 47.90 per 100 population
    UAE (9.77 million) 27.107 per 100 population
    United Kingdom (67 million) 10.79 per 100 population

    ...

    European Union (446 million) 2.11 per 100 population

    Still @Nigel_Foremain reckons "big" "muscle" works when it comes to pharmaceuticals. "Big" doesn't work. "Muscle" doesn't work.

    Small countries nimbly looking after themselves works.

    Bear in mind, that % covers the entire population. But 21% of the UK population is under 18. So, as we have no plans to vaccinate Da Yoof yet, we have actually jabbed 10.79m of the total 53m pool - we have done over 20% of the adult population of the UK.

    And we have probably jabbed a million more by now - so we are at 22.5% as of this moment.
    Half-jabbed...
    Which we are repeatedly told confer the majority of the protection.
    Yes, we are repeatedly told that in the UK. A wing and a prayer springs to mind.
    C'mon, you're not subscribing to that BMA nonsense are you? There's MASSIVE evidence around the world that the first jab, certainly of the Pfizer/BioNTech vaccine, provides a very high degree of protection, both in the published clinical trial data and in the real-world experience coming out of Israel. For the AZ vaccine, the boss himself confirmed the same yesterday.
    As I said, it may be a gamble that comes off, but it is a gamble.

    Israel is sticking to the protocol, so we have to wait until March to see if our different protocol works.
    Isn't sticking to three weeks a gamble on the other side of the bet though? You are precluding people from Jab 1 to give others Jab 2.

    That's a gamble in and of itself.
    You would be following the science, not gambling on anticipating it.

    Gambles often come off, but gamblers should know there is no such thing as a sure thing.

    If the 90% figure is correct, the delayed strategy is entirely justified. I come at this from the angle of someone who would have not done things the UK way.
    All people are saying, all I am saying, is that there was no trial designed specifically to determine the efficacy of a single jab although there are data from the two-jab trials which are very informative.

    As such, the manufacturers, and increasingly it seems the medico-scientists won't endorse a single jab regime.

    Because no one knows. Yes infection rates drop off as we have seen from that famous graph vs placebo, but no one knows after or between that what happens. Because it wasn't in a designed trial.
    AZ CEO was surely endorsing a single jab in his interview, saying "First of all, we believe that the efficacy of one dose is sufficient: 100 percent protection against severe disease and hospitalisation"

    Sounds like a decent endorsement from a manufacturer?
  • MysticroseMysticrose Posts: 4,688

    Worth repeating, it is thought deliveries next week will be a 1/3 down on this week....

    It is thought by whom?
  • FloaterFloater Posts: 14,207
    A wrestling tournament and no masks required - well guess what happened next...

    https://twitter.com/DrEricDing/status/1354244068751126531
  • FrancisUrquhartFrancisUrquhart Posts: 82,092
    edited January 2021
    Alistair said:

    wallstreetbets fucking up Citron (the hedge fund not the car company) is absolutely glorious.

    That is a crazy story, although some suggestion it isn't quite all WallStreetBets doing. Not quite WireCard levels of insanity, but still nuts.
  • Casino_RoyaleCasino_Royale Posts: 60,487

    TOPPING said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Yes it is significant.

    @MarqueeMark will fill you in on the details.
    This is what my conference call was about.

    We are more f*cked than a stepmom on Pornhub when our 18 month clearing exemption ends and it isn't permanently renewed.

    But those of us in the financial services sector we rank lower than fish.
    Other than a hostile act of petty vengeance what reason would tbe EU have to give clearing equivalence to US but not UK?
    Because the US companies have agreed to stick to the EU rules, whilst we want to ignore them. The EU position is if you want equivalency you have to stick to our rules, the US says fine, the UK less so.

    Honestly, 'liquidation periods' and 'anti procyclicality measure' is all the rage.
    I very much doubt the US has agreed to follow the EU's regulatory regime.
  • TOPPINGTOPPING Posts: 42,992

    TOPPING said:

    TOPPING said:

    kinabalu said:

    RobD said:

    kinabalu said:

    RobD said:

    kinabalu said:

    ydoethur said:

    ydoethur said:

    eek said:

    Nigelb said:


    It would only be interesting, indeed astonishing, if such caveats weren't in the contract.

    It is completely inconceivable that the contract wouldn't include lots of such caveats. There is absolutely no way AZ would have given a firm commitment on delivery dates for a brand-new vaccine, involving new production facilities and dependent on other suppliers who themselves were also doing things for the first time, all in a super-fast timescale.
    As AZ CEO has continually stated the contract is based on best endeavors.

    I'm actually surprised how polite he is being in public considering the games the EU seem to be playing.
    https://twitter.com/danielboffey/status/1354401225995911169?s=20
    I don't know what the EU think they're playing at. They really are in a negotiation where AZ hold all the cards. After all, if the EU get too bolshie AZ have the option to simply walk away from the contract, close their European factory and concentrate on other markets.

    And there is exactly feck all the EU can do about it.

    So the 'win' here for the EU is they accept a lower delivery than they want, and the lose is that they get none at all.
    Wrong. The EU is one of the largest markets for pharmaceuticals in the world. That gives them a lot of muscle. AZ will not want to antagonise them more than necessary, so no, AZ do not hold all the cards, far from it.
    So - just to be clear - the EU might ban AZ from operating in the EU altogether if they decide to abrogate a contract?

    Which would cause no medicine shortages of any kind, I trust?

    The EU are behaving like complete fools. It's like watching the DUP over Theresa May's deal - only worse, because you expect the DUP to behave like idiots.
    The EU feels that AZ have legged them over. So they are making a fuss.
    A resolution will be found that puts the EU in a better position than if they had not made a fuss.
    This is what I predict. Bet I'm right.
    At the detriment to who?
    I fear it might be you, Rob. But let's hope not.
    It was a legitimate question. The EU are seeking to divert supplies rightfully destined for the UK.
    Not really. That's a simplistic and jaundiced view. They are "rightfully" seeking to reduce their shortfall. In general, with fixed vaccine supply, every shot someone has means somebody else did not have it. Why are we diverting jabs from Italy? Why is Israel diverting jabs from us? Etc. It all depends on the contracts, the money, the moral view, the WHO, the balance of power, the politics etc etc. Bottom line is as I summarized and people should stop sanctimoniously moaning unless and until something that warrants it occurs. Which it hasn't yet. All that's happening is a frenzy of europhobes mutually wanking each other off and wallowing in europhobia. I'm finding it infantile and tedious.
    "Rightfully"?

    The EU signed their contracts three months late. It isn't europhobia to point this out.

    Had Johnson's Government signed contracts three months after the EU and the UK was struggling as a result then would it be Anglophobia to point that out?
    Good point. Can you please share that link again to the contract (did someone quote an extract upthread?).

    Thanks.
    https://www.repubblica.it/cronaca/2021/01/26/news/interview_pascal_soriot_ceo_astrazeneca_coronavirus_covid_vaccines-284349628/

    You said that the UK signed the AZ vaccine contract three months before EU, so you had more time to tweak and fix the potential disruptions of the supply. Why then did you commit to similar contracts with the EU, if you knew that in a very short time there could be problems like the one the EU supply chain is experiencing right now?
    "First of all, we have different plants and they have different yields and different productivity. One of the plans with the highest yield is in the UK because it started earlier. It also had its own issues, but we solved all, it has a good productivity, but it's the UK plant because it started earlier. Anyway, we didn't commit with the EU, by the way. It's not a commitment we have to Europe: it’s a best effort, we said we are going to make our best effort. The reason why we said that is because Europe at the time wanted to be supplied more or less at the same time as the UK, even though the contract was signed three months later. So we said, “ok, we're going to do our best, we’re going to try, but we cannot commit contractually because we are three months behind UK”. We knew it was a super stretch goal and we know it's a big issue, this pandemic. But our contract is not a contractual commitment. It's a best effort. Basically we said we're going to try our best, but we can't guarantee we're going to succeed. In fact, getting there, we are a little bit delayed”.

    Oops. 🤦🏻‍♂️
    Thanks has the contract been released?
    Why should it be? Unless you're saying the CEO is lying in saying that it was a best endeavours contract? Is that what you're claiming? 🤔
    Good point because no CEO in the history of CEOs has ever lied.

    So we don't have the contract is what you're saying?
  • MalmesburyMalmesbury Posts: 50,361
    kinabalu said:

    RobD said:

    As well as lots of caveats around 'best endeavours, I bet there are two further conditions in the AZ-EU contract:

    1. 'Subject to approval by the EMA', which would be an interesting one to bring into the mix.

    2. A clause stipulating that AZ won't favour other clients over the EU. The EU might think this gives them the right to dip into our supplies, but I doubt whether a proper reading of the various contracts would support that, assuming the AZ lawyers know what they are doing (which is a very, very good assumption).

    I mean it is a bunch of half-rate politicians that couldn't make it in national politics vs. lawyers that probably charge thousands an hour.
    Von der Leyen is leagues above corporate lawyer material.
    Her work as German defence minister was er.... interesting.

    Essentially, she won the Gavin Williamson award for skill in running her department. Beating the real Gavin Williamson.....
  • kinabalukinabalu Posts: 42,213
    HYUFD said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Leavers still getting what they voted for though.

    Leave the EU tick, end free movement tick, keep Nissan in Sunderland tick, reduce the influence of the City of London tick
    A smaller City is on my (very short) list of TBOBs - tangible benefits of Brexit. Trouble is, the bits I wanted to be smaller - the spivvy cowboy bits - are those likely to prosper. So it's come off. All that's left on there now is cheaper tampons and houses.
  • RobDRobD Posts: 59,933

    kinabalu said:

    RobD said:

    As well as lots of caveats around 'best endeavours, I bet there are two further conditions in the AZ-EU contract:

    1. 'Subject to approval by the EMA', which would be an interesting one to bring into the mix.

    2. A clause stipulating that AZ won't favour other clients over the EU. The EU might think this gives them the right to dip into our supplies, but I doubt whether a proper reading of the various contracts would support that, assuming the AZ lawyers know what they are doing (which is a very, very good assumption).

    I mean it is a bunch of half-rate politicians that couldn't make it in national politics vs. lawyers that probably charge thousands an hour.
    Von der Leyen is leagues above corporate lawyer material.
    Her work as German defence minister was er.... interesting.

    Essentially, she won the Gavin Williamson award for skill in running her department. Beating the real Gavin Williamson.....
    Not to mention the plagiarism.
  • YBarddCwscYBarddCwsc Posts: 7,172
    edited January 2021

    Its seems Drakeford has stopped storing vaccines for a rainy day as if he is some squirrel burying his nuts for winter.
    It would be so, so wonderful if Mark 'Loser' Drakeford lucks out & wins the race.

    I could hug the big, gruff, adorable sweetie. I have never said a word against him.

    It may be the first time Mark has won anything, but he is such a 'big tent' kinda person, I am sure he'll invite the whole of Wales up onto the winner's podium to share the triumph.

    And Mark and BigG and YDoethur and YBarddCwsc and MexicanPete will all be reconciled & we will party together.
  • eekeek Posts: 28,398

    TOPPING said:

    TOPPING said:

    TOPPING said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Yes it is significant.

    @MarqueeMark will fill you in on the details.
    This is what my conference call was about.

    We are more f*cked than a stepmom on Pornhub when our 18 month clearing exemption ends and it isn't permanently renewed.

    But those of us in the financial services sector we rank lower than fish.
    Other than a hostile act of petty vengeance what reason would tbe EU have to give clearing equivalence to US but not UK?
    Because we haven't been negotiating for it?
    Fish >> Finance remember.
    I wouldn't mind but we didn't even win on the fish.
    I know, but don't worry we're not important, it isn't like the banking/insurance/financial services is the largest contributor to the Exchequer.

    Oh man
    I'm sure the death of the City of London (which to some extent this news seems to be) will be the lead story on today's news programs.

    Were it not for the lockdown being extended another 3 weeks and the fact it's technical mumbo-jumbo that few people will understand.
  • TOPPINGTOPPING Posts: 42,992

    TOPPING said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Yes it is significant.

    @MarqueeMark will fill you in on the details.
    This is what my conference call was about.

    We are more f*cked than a stepmom on Pornhub when our 18 month clearing exemption ends and it isn't permanently renewed.

    But those of us in the financial services sector we rank lower than fish.
    Other than a hostile act of petty vengeance what reason would tbe EU have to give clearing equivalence to US but not UK?
    Because the US companies have agreed to stick to the EU rules, whilst we want to ignore them. The EU position is if you want equivalency you have to stick to our rules, the US says fine, the UK less so.

    Honestly, 'liquidation periods' and 'anti procyclicality measure' is all the rage.
    I very much doubt the US has agreed to follow the EU's regulatory regime.
    They already do. In Europe.

  • It is quite possible -- if the EU continue to behave like this -- that it magnifies Boris' "success".

    Is CCHQ advIsing the EU ?

    Because i really cannot think of much that could help Boris more than the EU over-reacting and blocking vaccine exports.

    It simultaneously focuses voters' attention on Boris' one big success in the COVID pandemic, as well as one big advantage of Brexit.

    And by over-reacting, the EU look like a mobster state.

    Why does the EU give a damn how this makes Boris Johnson look? It's a very Anglocentric view of things.

    The point is WE give a damn. This is a betting site, and there are elections coming up.

    This is politicalbetting.com, not remainerwanking.com.

    (And don't ever call me ANGLOcentric, again).
    Look, my point was simply that the EU's approach is understandable from their perspective. I agree it tends to help Johnson politically, looked at from a betting angle.

    On "Anglo" most dictionaries take the approach that the prefix "Anglo" in normal usage refers to the UK. I think the history is that an Anglo-American would be anyone from English speaking Europe which at the time would be the whole British Isles. Since Ireland separated, it tends to mean the remaining UK. I know that's not the original etymology, but blame centuries of common usage rather than me, please.

  • Nate Silver makes the correct point that it's just Bayesian versus frequentist statistics. Bayesian stats does have a "gambling" feel to it in that it assigns a prior probability to a hypothesis. But it's probably the better approach to the problem in this case - frequentist caution makes you feel better because you've followed the recipe, but probably doesn't have as good an expected pay-off.

    I'm not sure it's even that, because either way you have to assign a prior probability, given the limited supply and the massive urgency. @Foxy wants us to believe that it's less of a gamble to use the second dose on someone already vaccinated than as a first dose for someone else. In other words, he thinks that the efficacy of a single dose (over the few weeks we're talking about) is less than 50% of the efficacy of two doses. He hasn't explained where he gets this prior probability from; there is no data supporting it that I'm aware of. Conversely, there's plenty of data that the single dose efficacy is probably close to that of two doses, again over the few weeks we're talking about. Of course this isn't something for which we can cite full, properly-conducted clinical trials, but that proviso works equally on both sides of the argument.
  • kinabalu said:

    RobD said:

    As well as lots of caveats around 'best endeavours, I bet there are two further conditions in the AZ-EU contract:

    1. 'Subject to approval by the EMA', which would be an interesting one to bring into the mix.

    2. A clause stipulating that AZ won't favour other clients over the EU. The EU might think this gives them the right to dip into our supplies, but I doubt whether a proper reading of the various contracts would support that, assuming the AZ lawyers know what they are doing (which is a very, very good assumption).

    I mean it is a bunch of half-rate politicians that couldn't make it in national politics vs. lawyers that probably charge thousands an hour.
    Von der Leyen is leagues above corporate lawyer material.
    Her work as German defence minister was er.... interesting.

    Essentially, she won the Gavin Williamson award for skill in running her department. Beating the real Gavin Williamson.....
    Not to mention the plagiarism.
  • NickPalmerNickPalmer Posts: 21,533

    TOPPING said:

    Pulpstar said:

    Foxy said:

    Foxy said:

    Foxy said:

    RobD said:

    Foxy said:

    Best performing countries for Covid vaccine doses given out:

    Israel (9.05 million) 47.90 per 100 population
    UAE (9.77 million) 27.107 per 100 population
    United Kingdom (67 million) 10.79 per 100 population

    ...

    European Union (446 million) 2.11 per 100 population

    Still @Nigel_Foremain reckons "big" "muscle" works when it comes to pharmaceuticals. "Big" doesn't work. "Muscle" doesn't work.

    Small countries nimbly looking after themselves works.

    Bear in mind, that % covers the entire population. But 21% of the UK population is under 18. So, as we have no plans to vaccinate Da Yoof yet, we have actually jabbed 10.79m of the total 53m pool - we have done over 20% of the adult population of the UK.

    And we have probably jabbed a million more by now - so we are at 22.5% as of this moment.
    Half-jabbed...
    Which we are repeatedly told confer the majority of the protection.
    Yes, we are repeatedly told that in the UK. A wing and a prayer springs to mind.
    C'mon, you're not subscribing to that BMA nonsense are you? There's MASSIVE evidence around the world that the first jab, certainly of the Pfizer/BioNTech vaccine, provides a very high degree of protection, both in the published clinical trial data and in the real-world experience coming out of Israel. For the AZ vaccine, the boss himself confirmed the same yesterday.
    As I said, it may be a gamble that comes off, but it is a gamble.

    Israel is sticking to the protocol, so we have to wait until March to see if our different protocol works.
    Isn't sticking to three weeks a gamble on the other side of the bet though? You are precluding people from Jab 1 to give others Jab 2.

    That's a gamble in and of itself.
    You would be following the science, not gambling on anticipating it.

    Gambles often come off, but gamblers should know there is no such thing as a sure thing.

    If the 90% figure is correct, the delayed strategy is entirely justified. I come at this from the angle of someone who would have not done things the UK way.
    All people are saying, all I am saying, is that there was no trial designed specifically to determine the efficacy of a single jab although there are data from the two-jab trials which are very informative.

    As such, the manufacturers, and increasingly it seems the medico-scientists won't endorse a single jab regime.

    Because no one knows. Yes infection rates drop off as we have seen from that famous graph vs placebo, but no one knows after or between that what happens. Because it wasn't in a designed trial.
    AZ CEO was surely endorsing a single jab in his interview, saying "First of all, we believe that the efficacy of one dose is sufficient: 100 percent protection against severe disease and hospitalisation"

    Sounds like a decent endorsement from a manufacturer?
    There's belief in one's products, and then there's proof for clinical trials, two different things. Let's hope he's right, but we just don't know for sure, and nor does he. The whole area is one of weighing up alternative risks.
  • TOPPING said:

    TOPPING said:

    TOPPING said:

    kinabalu said:

    RobD said:

    kinabalu said:

    RobD said:

    kinabalu said:

    ydoethur said:

    ydoethur said:

    eek said:

    Nigelb said:


    It would only be interesting, indeed astonishing, if such caveats weren't in the contract.

    It is completely inconceivable that the contract wouldn't include lots of such caveats. There is absolutely no way AZ would have given a firm commitment on delivery dates for a brand-new vaccine, involving new production facilities and dependent on other suppliers who themselves were also doing things for the first time, all in a super-fast timescale.
    As AZ CEO has continually stated the contract is based on best endeavors.

    I'm actually surprised how polite he is being in public considering the games the EU seem to be playing.
    https://twitter.com/danielboffey/status/1354401225995911169?s=20
    I don't know what the EU think they're playing at. They really are in a negotiation where AZ hold all the cards. After all, if the EU get too bolshie AZ have the option to simply walk away from the contract, close their European factory and concentrate on other markets.

    And there is exactly feck all the EU can do about it.

    So the 'win' here for the EU is they accept a lower delivery than they want, and the lose is that they get none at all.
    Wrong. The EU is one of the largest markets for pharmaceuticals in the world. That gives them a lot of muscle. AZ will not want to antagonise them more than necessary, so no, AZ do not hold all the cards, far from it.
    So - just to be clear - the EU might ban AZ from operating in the EU altogether if they decide to abrogate a contract?

    Which would cause no medicine shortages of any kind, I trust?

    The EU are behaving like complete fools. It's like watching the DUP over Theresa May's deal - only worse, because you expect the DUP to behave like idiots.
    The EU feels that AZ have legged them over. So they are making a fuss.
    A resolution will be found that puts the EU in a better position than if they had not made a fuss.
    This is what I predict. Bet I'm right.
    At the detriment to who?
    I fear it might be you, Rob. But let's hope not.
    It was a legitimate question. The EU are seeking to divert supplies rightfully destined for the UK.
    Not really. That's a simplistic and jaundiced view. They are "rightfully" seeking to reduce their shortfall. In general, with fixed vaccine supply, every shot someone has means somebody else did not have it. Why are we diverting jabs from Italy? Why is Israel diverting jabs from us? Etc. It all depends on the contracts, the money, the moral view, the WHO, the balance of power, the politics etc etc. Bottom line is as I summarized and people should stop sanctimoniously moaning unless and until something that warrants it occurs. Which it hasn't yet. All that's happening is a frenzy of europhobes mutually wanking each other off and wallowing in europhobia. I'm finding it infantile and tedious.
    "Rightfully"?

    The EU signed their contracts three months late. It isn't europhobia to point this out.

    Had Johnson's Government signed contracts three months after the EU and the UK was struggling as a result then would it be Anglophobia to point that out?
    Good point. Can you please share that link again to the contract (did someone quote an extract upthread?).

    Thanks.
    https://www.repubblica.it/cronaca/2021/01/26/news/interview_pascal_soriot_ceo_astrazeneca_coronavirus_covid_vaccines-284349628/

    You said that the UK signed the AZ vaccine contract three months before EU, so you had more time to tweak and fix the potential disruptions of the supply. Why then did you commit to similar contracts with the EU, if you knew that in a very short time there could be problems like the one the EU supply chain is experiencing right now?
    "First of all, we have different plants and they have different yields and different productivity. One of the plans with the highest yield is in the UK because it started earlier. It also had its own issues, but we solved all, it has a good productivity, but it's the UK plant because it started earlier. Anyway, we didn't commit with the EU, by the way. It's not a commitment we have to Europe: it’s a best effort, we said we are going to make our best effort. The reason why we said that is because Europe at the time wanted to be supplied more or less at the same time as the UK, even though the contract was signed three months later. So we said, “ok, we're going to do our best, we’re going to try, but we cannot commit contractually because we are three months behind UK”. We knew it was a super stretch goal and we know it's a big issue, this pandemic. But our contract is not a contractual commitment. It's a best effort. Basically we said we're going to try our best, but we can't guarantee we're going to succeed. In fact, getting there, we are a little bit delayed”.

    Oops. 🤦🏻‍♂️
    Thanks has the contract been released?
    Why should it be? Unless you're saying the CEO is lying in saying that it was a best endeavours contract? Is that what you're claiming? 🤔
    Good point because no CEO in the history of CEOs has ever lied.

    So we don't have the contract is what you're saying?
    I'm saying we have the fact it was a best endeavours contract. A fact that is unchallenged.

    You don't need the contract, unless you're a bottom-feeding shit stirrer looking for mud to sling rather than acknowledging reality here.

    A best endeavours contract means something. Its not a commitment, and he explained why they wouldn't commit in the extract I gave you earlier - because the EU f***ed up and signed the deal late. Though he was a bit more diplomatic than that.

    The facts are all there in black and white.
  • TOPPINGTOPPING Posts: 42,992

    TOPPING said:

    Pulpstar said:

    Foxy said:

    Foxy said:

    Foxy said:

    RobD said:

    Foxy said:

    Best performing countries for Covid vaccine doses given out:

    Israel (9.05 million) 47.90 per 100 population
    UAE (9.77 million) 27.107 per 100 population
    United Kingdom (67 million) 10.79 per 100 population

    ...

    European Union (446 million) 2.11 per 100 population

    Still @Nigel_Foremain reckons "big" "muscle" works when it comes to pharmaceuticals. "Big" doesn't work. "Muscle" doesn't work.

    Small countries nimbly looking after themselves works.

    Bear in mind, that % covers the entire population. But 21% of the UK population is under 18. So, as we have no plans to vaccinate Da Yoof yet, we have actually jabbed 10.79m of the total 53m pool - we have done over 20% of the adult population of the UK.

    And we have probably jabbed a million more by now - so we are at 22.5% as of this moment.
    Half-jabbed...
    Which we are repeatedly told confer the majority of the protection.
    Yes, we are repeatedly told that in the UK. A wing and a prayer springs to mind.
    C'mon, you're not subscribing to that BMA nonsense are you? There's MASSIVE evidence around the world that the first jab, certainly of the Pfizer/BioNTech vaccine, provides a very high degree of protection, both in the published clinical trial data and in the real-world experience coming out of Israel. For the AZ vaccine, the boss himself confirmed the same yesterday.
    As I said, it may be a gamble that comes off, but it is a gamble.

    Israel is sticking to the protocol, so we have to wait until March to see if our different protocol works.
    Isn't sticking to three weeks a gamble on the other side of the bet though? You are precluding people from Jab 1 to give others Jab 2.

    That's a gamble in and of itself.
    You would be following the science, not gambling on anticipating it.

    Gambles often come off, but gamblers should know there is no such thing as a sure thing.

    If the 90% figure is correct, the delayed strategy is entirely justified. I come at this from the angle of someone who would have not done things the UK way.
    All people are saying, all I am saying, is that there was no trial designed specifically to determine the efficacy of a single jab although there are data from the two-jab trials which are very informative.

    As such, the manufacturers, and increasingly it seems the medico-scientists won't endorse a single jab regime.

    Because no one knows. Yes infection rates drop off as we have seen from that famous graph vs placebo, but no one knows after or between that what happens. Because it wasn't in a designed trial.
    AZ CEO was surely endorsing a single jab in his interview, saying "First of all, we believe that the efficacy of one dose is sufficient: 100 percent protection against severe disease and hospitalisation"

    Sounds like a decent endorsement from a manufacturer?
    Yep that is true. Interesting. Pfizer's response was difference IIRC (don't have it to hand).
  • AlistairAlistair Posts: 23,670

    Alistair said:

    wallstreetbets fucking up Citron (the hedge fund not the car company) is absolutely glorious.

    That is a crazy story, although some suggestion it isn't quite all WallStreetBets doing. Not quite WireCard levels of insanity, but still nuts.
    No indeed. I believe Blackrock have made 1.5 billion on this due to their holdings of GAME.

    It is still absolutely lol-tastic though. "Short selling helps price discovery" - apparently the price is on the moon.
  • CarnyxCarnyx Posts: 42,881


    Nate Silver makes the correct point that it's just Bayesian versus frequentist statistics. Bayesian stats does have a "gambling" feel to it in that it assigns a prior probability to a hypothesis. But it's probably the better approach to the problem in this case - frequentist caution makes you feel better because you've followed the recipe, but probably doesn't have as good an expected pay-off.

    I'm not sure it's even that, because either way you have to assign a prior probability, given the limited supply and the massive urgency. @Foxy wants us to believe that it's less of a gamble to use the second dose on someone already vaccinated than as a first dose for someone else. In other words, he thinks that the efficacy of a single dose (over the few weeks we're talking about) is less than 50% of the efficacy of two doses. He hasn't explained where he gets this prior probability from; there is no data supporting it that I'm aware of. Conversely, there's plenty of data that the single dose efficacy is probably close to that of two doses, again over the few weeks we're talking about. Of course this isn't something for which we can cite full, properly-conducted clinical trials, but that proviso works equally on both sides of the argument.
    Hmm, is there not a hidden assumption there? That the effect X of the single dose lasts as well time wise as the effect x + y of the single dose followed up by a second one within three weeks?
  • FrancisUrquhartFrancisUrquhart Posts: 82,092
    edited January 2021

    Worth repeating, it is thought deliveries next week will be a 1/3 down on this week....

    It is thought by whom?
    The supply of covid vaccine to the North West region is set to be cut by around a third in February, seemingly due to national shortages and the need for other regions to catch up with vaccinating their priority groups.

    https://www.hsj.co.uk/coronavirus/north-wests-vaccine-supply-cut-by-a-third/7029383.article

    Now the government have been a bit contradictory about if you do redirect and if so how much. Lets say some of that is due to redirection to other regions, but this does give a rough feel that there is significant reduction in the amount of new deliveries next week and the week after.
  • BluestBlueBluestBlue Posts: 4,556
    TOPPING said:

    eek said:

    HYUFD said:

    eek said:

    Is this significant or not for the City.

    https://twitter.com/nicktolhurst/status/1354418652154634247

    Leavers still getting what they voted for though.

    Leave the EU tick, end free movement tick, keep Nissan in Sunderland tick, reduce the influence of the City of London tick
    So you are happy that the biggest source of tax revenue is screwed due to decisions Boris made last year see

    https://twitter.com/nicktolhurst/status/1354419288313126923
    @HYUFD is not happy he is a remainer. I'm sure @Philip_Thompson and @BluestBlue are happy though.

    Not that they understand one end of it all.

    But sovereignty. And perhaps they can ring up Sleepy Joe and explain to him how his banks and the US are losing it with this deal.

    I'm afraid I'm yet another one who voted Remain, as I've mentioned before, though I am indeed happy to accept the outcome of Brexit. What exactly would the EU have demanded in exchange for safeguarding the primacy of the City?
  • TOPPING said:

    Pulpstar said:

    Foxy said:

    Foxy said:

    Foxy said:

    RobD said:

    Foxy said:

    Best performing countries for Covid vaccine doses given out:

    Israel (9.05 million) 47.90 per 100 population
    UAE (9.77 million) 27.107 per 100 population
    United Kingdom (67 million) 10.79 per 100 population

    ...

    European Union (446 million) 2.11 per 100 population

    Still @Nigel_Foremain reckons "big" "muscle" works when it comes to pharmaceuticals. "Big" doesn't work. "Muscle" doesn't work.

    Small countries nimbly looking after themselves works.

    Bear in mind, that % covers the entire population. But 21% of the UK population is under 18. So, as we have no plans to vaccinate Da Yoof yet, we have actually jabbed 10.79m of the total 53m pool - we have done over 20% of the adult population of the UK.

    And we have probably jabbed a million more by now - so we are at 22.5% as of this moment.
    Half-jabbed...
    Which we are repeatedly told confer the majority of the protection.
    Yes, we are repeatedly told that in the UK. A wing and a prayer springs to mind.
    C'mon, you're not subscribing to that BMA nonsense are you? There's MASSIVE evidence around the world that the first jab, certainly of the Pfizer/BioNTech vaccine, provides a very high degree of protection, both in the published clinical trial data and in the real-world experience coming out of Israel. For the AZ vaccine, the boss himself confirmed the same yesterday.
    As I said, it may be a gamble that comes off, but it is a gamble.

    Israel is sticking to the protocol, so we have to wait until March to see if our different protocol works.
    Isn't sticking to three weeks a gamble on the other side of the bet though? You are precluding people from Jab 1 to give others Jab 2.

    That's a gamble in and of itself.
    You would be following the science, not gambling on anticipating it.

    Gambles often come off, but gamblers should know there is no such thing as a sure thing.

    If the 90% figure is correct, the delayed strategy is entirely justified. I come at this from the angle of someone who would have not done things the UK way.
    All people are saying, all I am saying, is that there was no trial designed specifically to determine the efficacy of a single jab although there are data from the two-jab trials which are very informative.

    As such, the manufacturers, and increasingly it seems the medico-scientists won't endorse a single jab regime.

    Because no one knows. Yes infection rates drop off as we have seen from that famous graph vs placebo, but no one knows after or between that what happens. Because it wasn't in a designed trial.
    AZ CEO was surely endorsing a single jab in his interview, saying "First of all, we believe that the efficacy of one dose is sufficient: 100 percent protection against severe disease and hospitalisation"

    Sounds like a decent endorsement from a manufacturer?
    There's belief in one's products, and then there's proof for clinical trials, two different things. Let's hope he's right, but we just don't know for sure, and nor does he. The whole area is one of weighing up alternative risks.
    What we do know for sure is the consequences of giving zero doses to somebody.

    I wish those piping up in favour of bumping public sector workers up the list, or giving double-doses to the same people, were open and honest about who they would bump down the list to compensate.

    Which seven million people from the 14 million highest priority would you choose to leave 100% unvaccinated in order to give double-doses to the first 7 million instead?
  • TOPPINGTOPPING Posts: 42,992

    TOPPING said:

    TOPPING said:

    TOPPING said:

    kinabalu said:

    RobD said:

    kinabalu said:

    RobD said:

    kinabalu said:

    ydoethur said:

    ydoethur said:

    eek said:

    Nigelb said:


    It would only be interesting, indeed astonishing, if such caveats weren't in the contract.

    It is completely inconceivable that the contract wouldn't include lots of such caveats. There is absolutely no way AZ would have given a firm commitment on delivery dates for a brand-new vaccine, involving new production facilities and dependent on other suppliers who themselves were also doing things for the first time, all in a super-fast timescale.
    As AZ CEO has continually stated the contract is based on best endeavors.

    I'm actually surprised how polite he is being in public considering the games the EU seem to be playing.
    https://twitter.com/danielboffey/status/1354401225995911169?s=20
    I don't know what the EU think they're playing at. They really are in a negotiation where AZ hold all the cards. After all, if the EU get too bolshie AZ have the option to simply walk away from the contract, close their European factory and concentrate on other markets.

    And there is exactly feck all the EU can do about it.

    So the 'win' here for the EU is they accept a lower delivery than they want, and the lose is that they get none at all.
    Wrong. The EU is one of the largest markets for pharmaceuticals in the world. That gives them a lot of muscle. AZ will not want to antagonise them more than necessary, so no, AZ do not hold all the cards, far from it.
    So - just to be clear - the EU might ban AZ from operating in the EU altogether if they decide to abrogate a contract?

    Which would cause no medicine shortages of any kind, I trust?

    The EU are behaving like complete fools. It's like watching the DUP over Theresa May's deal - only worse, because you expect the DUP to behave like idiots.
    The EU feels that AZ have legged them over. So they are making a fuss.
    A resolution will be found that puts the EU in a better position than if they had not made a fuss.
    This is what I predict. Bet I'm right.
    At the detriment to who?
    I fear it might be you, Rob. But let's hope not.
    It was a legitimate question. The EU are seeking to divert supplies rightfully destined for the UK.
    Not really. That's a simplistic and jaundiced view. They are "rightfully" seeking to reduce their shortfall. In general, with fixed vaccine supply, every shot someone has means somebody else did not have it. Why are we diverting jabs from Italy? Why is Israel diverting jabs from us? Etc. It all depends on the contracts, the money, the moral view, the WHO, the balance of power, the politics etc etc. Bottom line is as I summarized and people should stop sanctimoniously moaning unless and until something that warrants it occurs. Which it hasn't yet. All that's happening is a frenzy of europhobes mutually wanking each other off and wallowing in europhobia. I'm finding it infantile and tedious.
    "Rightfully"?

    The EU signed their contracts three months late. It isn't europhobia to point this out.

    Had Johnson's Government signed contracts three months after the EU and the UK was struggling as a result then would it be Anglophobia to point that out?
    Good point. Can you please share that link again to the contract (did someone quote an extract upthread?).

    Thanks.
    https://www.repubblica.it/cronaca/2021/01/26/news/interview_pascal_soriot_ceo_astrazeneca_coronavirus_covid_vaccines-284349628/

    You said that the UK signed the AZ vaccine contract three months before EU, so you had more time to tweak and fix the potential disruptions of the supply. Why then did you commit to similar contracts with the EU, if you knew that in a very short time there could be problems like the one the EU supply chain is experiencing right now?
    "First of all, we have different plants and they have different yields and different productivity. One of the plans with the highest yield is in the UK because it started earlier. It also had its own issues, but we solved all, it has a good productivity, but it's the UK plant because it started earlier. Anyway, we didn't commit with the EU, by the way. It's not a commitment we have to Europe: it’s a best effort, we said we are going to make our best effort. The reason why we said that is because Europe at the time wanted to be supplied more or less at the same time as the UK, even though the contract was signed three months later. So we said, “ok, we're going to do our best, we’re going to try, but we cannot commit contractually because we are three months behind UK”. We knew it was a super stretch goal and we know it's a big issue, this pandemic. But our contract is not a contractual commitment. It's a best effort. Basically we said we're going to try our best, but we can't guarantee we're going to succeed. In fact, getting there, we are a little bit delayed”.

    Oops. 🤦🏻‍♂️
    Thanks has the contract been released?
    Why should it be? Unless you're saying the CEO is lying in saying that it was a best endeavours contract? Is that what you're claiming? 🤔
    Good point because no CEO in the history of CEOs has ever lied.

    So we don't have the contract is what you're saying?
    I'm saying we have the fact it was a best endeavours contract. A fact that is unchallenged.

    You don't need the contract, unless you're a bottom-feeding shit stirrer looking for mud to sling rather than acknowledging reality here.

    A best endeavours contract means something. Its not a commitment, and he explained why they wouldn't commit in the extract I gave you earlier - because the EU f***ed up and signed the deal late. Though he was a bit more diplomatic than that.

    The facts are all there in black and white.
    How do we know the fact that it is a best endeavours contract. Because the CEO said so (apols have been a bit out of the loop here)?

    And "bottom-feeding shit stirrer" to look at the terms of a contract. LOL

    Please let me sell you a house or indeed anything at all in the near future!
  • EndillionEndillion Posts: 4,976

    England only vaccination data out

    1st dose 2nd dose
    Total 259306 1001
    East Of England 29244 47
    London 43555 445
    Midlands 41813 131
    North East And Yorkshire 38513 56
    North West 35271 95
    South East 39181 177
    South West 29908 47

    Bit disappointing while its up 10% vs yesterday its down vs 1 week ago:

    Total: 260,307 -41,055
    First: 259,306 -39,067
    Second: 1,001 -1,988
    Weren't we pre-warned about this? The run rate increased substantially last week, but was set to drop this week due to supply constraints.
  • MortimerMortimer Posts: 14,127
    Floater said:

    A wrestling tournament and no masks required - well guess what happened next...

    https://twitter.com/DrEricDing/status/1354244068751126531

    One of my current pet peeves is the assumption, especially prevalent on Twitter, that masks are the solution. It is obvious that not having the tournament is the solution.....
This discussion has been closed.