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Cooper moves to third in the SKS successor betting – politicalbetting.com

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  • AnabobazinaAnabobazina Posts: 23,486
    glw said:

    Data isn't from Israel, its from South Africa. It has been passed to the Israeli's to look at, but somebody leaks it to a media channel. Nothing is confirmed yet.

    Yep, but summarising so far about 30% more transmissible, up to twice the reinfection rate, about the same moribidity for the vaccinated, but about double for the unvaccinated. No aspect here is good news, this is worse or equal to Delta across the board. The only saving grace is that vaccines still seem to work well enough to keep most people out of hospital. Of course the sample size here is so small that these figures are only preliminary and likely to shift a fair bit as more data comes in and time passes.
    Apart from the minor point that the vaccines work.
  • MexicanpeteMexicanpete Posts: 28,374
    isam said:

    isam said:

    ydoethur said:

    kinabalu said:

    kinabalu said:

    kinabalu said:

    MaxPB said:

    kinabalu said:

    TOPPING said:

    kinabalu said:

    For the zillionth time (does this really need repeating??) more regulation is not synonymous with better regulation. It's one of the most bizarre features of people on the Left that they seem to be totally incapable of getting their heads around this simplest of propositions. And I think it's a genuine intellectual failure in them, not just the obvious one of seeking to excuse a Labour Chancellor for the catastrophic dog's breakfast he made of financial regulation.

    Semi agreed. The regime put in place was rubbish and failed but there is no way on this earth that the old one, let alone any the Cons (who were fully signed up to 'light touch') would conceivably have implemented, could have headed off the crash of 08 or mitigated its impact on us to any significant degree.
    There is "the crash of 08" with its attendant CDS and so forth, and there is the first bank panic in the UK for XX years with people queuing round the block to get their money out. The former of course not; the latter, perhaps.
    The business model in question would need to have been prohibited in order to stop that. But the political culture of the time was 'these guys know what they're doing, leave them be, count the tax pounds'. Would this have been different with George Osborne or John McDonnell instead of Gordon Brown as Chancellor? (I now copy your last sentence).
    The Bank of England is still in charge of monitoring bank capital ratios and blocks RBS from buying ABN Amro. The Bank of England tells Northern Rock it's business model is built on sand and to hold 8% capital, not 0%. The Bank of England tells HBOS the same and to hold 8% reserve capital.

    That alone changes the nature and severity of the banking crisis in 08. You want to rewrite history and pretend it was investment banks that failed in the UK, it wasn't, it was standard old retail banks that shat the bed and needed bailing out.

    I still think we should have let all of them go bankrupt and stood behind the depositors. It was a mistake to for the state to step in and socialise losses.
    I'm not rewriting history. You're constructing an alternative history whereby under the 'light touch' laissez faire Tories, the City's reckless exuberance (being kind there) would have been tamed to such an extent that when global money markets had their near fatal seizure we here would have been largely protected. I find this fanciful in the extreme. Also the distinction between retail and investment banks' behaviour isn't a clear one. Eg, a large part of RBS's problem was paying a ludicrous amount for the poison pill that was ABN. It was full of junk. Barclays and the much vaunted Bob Diamond avoided that fate by the sheer dumb luck of being outbid by a bigger and more hubristic fool. Investment banks (and bankers) played a full part in the debacle on both sides of the Atlantic.
    Ask yourself this, why after such a long period of it not happening why did so many banks go bust after Gordon Brown changed the rules?

    Now I've spent the last decade working in banking and financial services regulation/compliance so I'm obviously an ingénue in these matters, so be gentle.
    Because the 08 crash and subsequent markets seizure exposed the fact that the City had long abdicated on risk management in a breathless chase for remuneration and status. Is my answer.

    Unless you're talking about a stream of failures before that?
    That Tory manifesto from 2005 again, in the wake of the pressure from Hannan and others' a year earlier to fully "Icelandise" the UK financial sector :

    "The best guarantee of future prosperity is a dynamic economy. New technology and the speed of global capital flows punish the inflexible and the sluggish. We need to reward risk-taking ...."
    Yep. There is mucho bollocks being talked in places. Brown deserves his big black mark on this - he fell for the myth of City 'flair plus competence' and he WAS the CoE for heavens sake - but there is simply no way it wouldn't have panned out similar or worse under the Cons. But of course we can't prove this. So the claim persists. Grrr.
    A better example might be Black Wednesday. Brown was a full-throated supporter of the ERM long after it had become obvious even to Major and Lamont that we would have to withdraw. But nobody ever holds that against him even though had he been in charge things would have been fifty times worse.

    Similarly it was as well for George Osborne's reputation, such as remains, that he wasn't in charge when Lehmanns went belly up. Mouse in the headlights would describe his demeanour quite well.
    You have perfectly explained why contrary to what BigG and Isam are touting, it matters not a jot if Starmer calls Covid wrong today. It is far more important for Johnson to call it right however.
    It matters in the context of the next GE campaign - The Tories, if Boris is right, can point out they freed us whilst Labour clamoured for lockdown - it is all about the next GE campaign. I was thinking earlier on that pollsters shouldn't ask "How would you vote if there were a General Election tomorrow" but "How would you vote if there were a General Election tomorrow, taking into account there would have had been 2 months campaigning" and "Who do you think will perform better in the Election debates"
    No it doesn't, unless every couple of months between now and the next GE Starmer keeps calling it wrong and Johnson keeps calling it right, or there is indeed an election tomorrow. Besides which Covid will be just one of a number of GE issues for Johnson to call right by then. Oh, and Johnson won't do the debates he will again use a surrogate.
    You think the only political topics people have talked about for the last two years won't have any bearing on the next GE? Fair enough, agree to disagree
    Of course they will, but don't you think the bulk of the vaccine bonus is already baked in for Johnson, there is probably a little more to come from the boosters.

    When the Government's Covid post-mortem analysis is in Johnson's performance report will be mixed to say the least.

    I am also not convinced Johnson getting Christmas right gives him many smartie points, getting it wrong loses lots.

    Starmer's call by contrast is largely irrelevant.
  • geoffwgeoffw Posts: 8,720
    ".. as more data comes come in .."
  • moonshinemoonshine Posts: 5,748
    MaxPB said:

    Eabhal said:

    What's the play if Omicron has no vaccine escape but is absolutely devastating to the unvaxxed?

    An exceptionally tough decision for the PM. An NHS overrun with anti-vaxxers hurts all of us, so do we put then at the back of the queue for treatment? Or do we have to accept a lockdown?

    We don't really have enough people in the non-immune categories for that to happen. The LSHTM model was quite prescient in that it predicted what hospitalisations would look like if everyone in the country was exposed to the virus tomorrow, it works out to about 40k people hospitalised here. It's not an earth shattering figure.
    That Israeli story if true, indicates by far the best strategy would be to mop up the last of the anti vaxxers with nature’s own vaccine now. Rather than taking any useful measures which might suppress the spread of delta and leave a bigger pool of naive immune systems for Omicron to smash into once it’s the ascendant strain.

    Which happily enough, seems to be exactly the consequence of this week’s policy decisions. Might be luck but let’s give benefit of the doubt, looks like someone has thought this through quite cleverly.
  • IshmaelZIshmaelZ Posts: 21,830

    IshmaelZ said:

    IshmaelZ said:

    Pulpstar said:

    @sailorrooscout
    ·
    1m

    PRELIMINARY DATA but good news for your afternoon! Pfizer vaccine’s is only SLIGHTLY less effective in preventing infection with Omicron than with Delta- 90% as opposed to 95%- while it is AS EFFECTIVE in preventing serious symptoms- around 93% – at least for those boosted!
    There are indications that individuals fully vaccinated against the coronavirus, within six months or with the booster, are also protected against the Omicron variant, Health Minister Nitzan Horowitz said Tuesday, after another two cases of individuals infected with the variant were identified, bringing the total to four. “In the coming days we will have more accurate information about the efficacy of the vaccine against Omicron but there is already room for optimism, and there are initial indications that those who are vaccinated with a vaccine STILL valid or with a booster, will also be protected from this variant.” In addition, according to the report, the ability of the variant to infect is higher than Delta but not as much as feared- around 1.3 times higher.
    At the same time, those not inoculated have a 2.4 times greater chances of developing serious symptoms- a significant figure. You can read this and more here: https://jpost.com/health-and-wellness/coronavirus/covid-1st-data-about-vaccine-efficacy-against-omicron-expected-tuesday-687392

    TLDR Get vaccinated, get boosted.

    Looks like fantastic news and a vindication of expediting the booster programme. Fair play to Javid.
    Two cardiologists from Sheba Medical Center were verified as infected with the Omicron variant, a spokesperson for the hospital confirmed.
    He said they were experiencing “very light symptoms.”
    One of the doctors, in his 50s, brought the variant into Israel on return from a medical conference in London.
    When was this chap in London I ask myself? I'll bet it doesn't fit with the original timeframe that this was cooked up in Botswana on Wednesday.
    Makes you wonder doesn't it.
    Not really, because if you ever thought detected in = cooked up in, in the first place, I doubt anything on earth has the power to make you actually think.
    Can I have a translation please.
    You just seem to be a bit off the pace, intellectually speaking. Like saying in 2021 that the discovery of dinosaur fossils makes you wonder about the theory that the world was created in mid October 4004 BC.
    I am glad that I am extremely comfortable in my own intellectual capabilities not to be concerned by a random person off the internet thinks.

    You also seemed to have misunderstood my point, which was I think it is becoming increasingly clear that this variant has been around a fair bit longer than just a few days. In fact we already know this from the confirmed cases. It then makes you wonder, just how long, no more "conspiracy" beyond that.
    But who in the name of God, assuming they can simultaneously walk and chew gum, ever deduced "this was only detected a few days ago, therefore this has only been around for a few days"?
  • isamisam Posts: 41,118

    isam said:

    isam said:

    ydoethur said:

    kinabalu said:

    kinabalu said:

    kinabalu said:

    MaxPB said:

    kinabalu said:

    TOPPING said:

    kinabalu said:

    For the zillionth time (does this really need repeating??) more regulation is not synonymous with better regulation. It's one of the most bizarre features of people on the Left that they seem to be totally incapable of getting their heads around this simplest of propositions. And I think it's a genuine intellectual failure in them, not just the obvious one of seeking to excuse a Labour Chancellor for the catastrophic dog's breakfast he made of financial regulation.

    Semi agreed. The regime put in place was rubbish and failed but there is no way on this earth that the old one, let alone any the Cons (who were fully signed up to 'light touch') would conceivably have implemented, could have headed off the crash of 08 or mitigated its impact on us to any significant degree.
    There is "the crash of 08" with its attendant CDS and so forth, and there is the first bank panic in the UK for XX years with people queuing round the block to get their money out. The former of course not; the latter, perhaps.
    The business model in question would need to have been prohibited in order to stop that. But the political culture of the time was 'these guys know what they're doing, leave them be, count the tax pounds'. Would this have been different with George Osborne or John McDonnell instead of Gordon Brown as Chancellor? (I now copy your last sentence).
    The Bank of England is still in charge of monitoring bank capital ratios and blocks RBS from buying ABN Amro. The Bank of England tells Northern Rock it's business model is built on sand and to hold 8% capital, not 0%. The Bank of England tells HBOS the same and to hold 8% reserve capital.

    That alone changes the nature and severity of the banking crisis in 08. You want to rewrite history and pretend it was investment banks that failed in the UK, it wasn't, it was standard old retail banks that shat the bed and needed bailing out.

    I still think we should have let all of them go bankrupt and stood behind the depositors. It was a mistake to for the state to step in and socialise losses.
    I'm not rewriting history. You're constructing an alternative history whereby under the 'light touch' laissez faire Tories, the City's reckless exuberance (being kind there) would have been tamed to such an extent that when global money markets had their near fatal seizure we here would have been largely protected. I find this fanciful in the extreme. Also the distinction between retail and investment banks' behaviour isn't a clear one. Eg, a large part of RBS's problem was paying a ludicrous amount for the poison pill that was ABN. It was full of junk. Barclays and the much vaunted Bob Diamond avoided that fate by the sheer dumb luck of being outbid by a bigger and more hubristic fool. Investment banks (and bankers) played a full part in the debacle on both sides of the Atlantic.
    Ask yourself this, why after such a long period of it not happening why did so many banks go bust after Gordon Brown changed the rules?

    Now I've spent the last decade working in banking and financial services regulation/compliance so I'm obviously an ingénue in these matters, so be gentle.
    Because the 08 crash and subsequent markets seizure exposed the fact that the City had long abdicated on risk management in a breathless chase for remuneration and status. Is my answer.

    Unless you're talking about a stream of failures before that?
    That Tory manifesto from 2005 again, in the wake of the pressure from Hannan and others' a year earlier to fully "Icelandise" the UK financial sector :

    "The best guarantee of future prosperity is a dynamic economy. New technology and the speed of global capital flows punish the inflexible and the sluggish. We need to reward risk-taking ...."
    Yep. There is mucho bollocks being talked in places. Brown deserves his big black mark on this - he fell for the myth of City 'flair plus competence' and he WAS the CoE for heavens sake - but there is simply no way it wouldn't have panned out similar or worse under the Cons. But of course we can't prove this. So the claim persists. Grrr.
    A better example might be Black Wednesday. Brown was a full-throated supporter of the ERM long after it had become obvious even to Major and Lamont that we would have to withdraw. But nobody ever holds that against him even though had he been in charge things would have been fifty times worse.

    Similarly it was as well for George Osborne's reputation, such as remains, that he wasn't in charge when Lehmanns went belly up. Mouse in the headlights would describe his demeanour quite well.
    You have perfectly explained why contrary to what BigG and Isam are touting, it matters not a jot if Starmer calls Covid wrong today. It is far more important for Johnson to call it right however.
    It matters in the context of the next GE campaign - The Tories, if Boris is right, can point out they freed us whilst Labour clamoured for lockdown - it is all about the next GE campaign. I was thinking earlier on that pollsters shouldn't ask "How would you vote if there were a General Election tomorrow" but "How would you vote if there were a General Election tomorrow, taking into account there would have had been 2 months campaigning" and "Who do you think will perform better in the Election debates"
    No it doesn't, unless every couple of months between now and the next GE Starmer keeps calling it wrong and Johnson keeps calling it right, or there is indeed an election tomorrow. Besides which Covid will be just one of a number of GE issues for Johnson to call right by then. Oh, and Johnson won't do the debates he will again use a surrogate.
    You think the only political topics people have talked about for the last two years won't have any bearing on the next GE? Fair enough, agree to disagree
    Of course they will, but don't you think the bulk of the vaccine bonus is already baked in for Johnson, there is probably a little more to come from the boosters.

    When the Government's Covid post-mortem analysis is in Johnson's performance report will be mixed to say the least.

    I am also not convinced Johnson getting Christmas right gives him many smartie points, getting it wrong loses lots.

    Starmer's call by contrast is largely irrelevant.
    I am saying it will give the Tories some ammo at the next GE - it is one of the biggest decisions in modern history - whether to impose restrictions of people freedoms or not. If Boris doesn't,and is proven correct, for a second time whilst Sir Keir is haranguing him to, of course the Tories will use it at the next GE, as well as their vaccine successes
  • CarlottaVanceCarlottaVance Posts: 60,216
    edited November 2021
    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
  • kinabalu said:

    kinabalu said:

    MaxPB said:

    kinabalu said:

    TOPPING said:

    kinabalu said:

    For the zillionth time (does this really need repeating??) more regulation is not synonymous with better regulation. It's one of the most bizarre features of people on the Left that they seem to be totally incapable of getting their heads around this simplest of propositions. And I think it's a genuine intellectual failure in them, not just the obvious one of seeking to excuse a Labour Chancellor for the catastrophic dog's breakfast he made of financial regulation.

    Semi agreed. The regime put in place was rubbish and failed but there is no way on this earth that the old one, let alone any the Cons (who were fully signed up to 'light touch') would conceivably have implemented, could have headed off the crash of 08 or mitigated its impact on us to any significant degree.
    There is "the crash of 08" with its attendant CDS and so forth, and there is the first bank panic in the UK for XX years with people queuing round the block to get their money out. The former of course not; the latter, perhaps.
    The business model in question would need to have been prohibited in order to stop that. But the political culture of the time was 'these guys know what they're doing, leave them be, count the tax pounds'. Would this have been different with George Osborne or John McDonnell instead of Gordon Brown as Chancellor? (I now copy your last sentence).
    The Bank of England is still in charge of monitoring bank capital ratios and blocks RBS from buying ABN Amro. The Bank of England tells Northern Rock it's business model is built on sand and to hold 8% capital, not 0%. The Bank of England tells HBOS the same and to hold 8% reserve capital.

    That alone changes the nature and severity of the banking crisis in 08. You want to rewrite history and pretend it was investment banks that failed in the UK, it wasn't, it was standard old retail banks that shat the bed and needed bailing out.

    I still think we should have let all of them go bankrupt and stood behind the depositors. It was a mistake to for the state to step in and socialise losses.
    I'm not rewriting history. You're constructing an alternative history whereby under the 'light touch' laissez faire Tories, the City's reckless exuberance (being kind there) would have been tamed to such an extent that when global money markets had their near fatal seizure we here would have been largely protected. I find this fanciful in the extreme. Also the distinction between retail and investment banks' behaviour isn't a clear one. Eg, a large part of RBS's problem was paying a ludicrous amount for the poison pill that was ABN. It was full of junk. Barclays and the much vaunted Bob Diamond avoided that fate by the sheer dumb luck of being outbid by a bigger and more hubristic fool. Investment banks (and bankers) played a full part in the debacle on both sides of the Atlantic.
    Ask yourself this, why after such a long period of it not happening why did so many banks go bust after Gordon Brown changed the rules?

    Now I've spent the last decade working in banking and financial services regulation/compliance so I'm obviously an ingénue in these matters, so be gentle.
    Because the 08 crash and subsequent markets seizure exposed the fact that the City had long abdicated on risk management in a breathless chase for remuneration and status. Is my answer.

    Unless you're talking about a stream of failures before that?
    They abdicated risk management when Gordon Brown removed the rules that ensured risk management, and the Bank of England oversight that were responsible for it.

    Brownian box ticking via thousands of forms isn't a substitute for a proper risk management system, and having a decent reserve ratio ranks pretty high on risk management.
  • moonshinemoonshine Posts: 5,748

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    How cheap is to sequence a genome now? Did it hit $1000 yet? What’s the explanation for why most countries are not even bothering to try?
  • LostPasswordLostPassword Posts: 18,394
    MaxPB said:

    Eabhal said:

    What's the play if Omicron has no vaccine escape but is absolutely devastating to the unvaxxed?

    An exceptionally tough decision for the PM. An NHS overrun with anti-vaxxers hurts all of us, so do we put then at the back of the queue for treatment? Or do we have to accept a lockdown?

    We don't really have enough people in the non-immune categories for that to happen. The LSHTM model was quite prescient in that it predicted what hospitalisations would look like if everyone in the country was exposed to the virus tomorrow, it works out to about 40k people hospitalised here. It's not an earth shattering figure.
    Our peak last winter was 39,254 people in hospital, so that study would suggest it's now impossible to exceed that figure, unless a variant can substantially evade existing immunity, or is substantially more likely to cause serious illness to those with no immunity than Delta.
  • IshmaelZIshmaelZ Posts: 21,830
    IshmaelZ said:

    IshmaelZ said:

    IshmaelZ said:

    Pulpstar said:

    @sailorrooscout
    ·
    1m

    PRELIMINARY DATA but good news for your afternoon! Pfizer vaccine’s is only SLIGHTLY less effective in preventing infection with Omicron than with Delta- 90% as opposed to 95%- while it is AS EFFECTIVE in preventing serious symptoms- around 93% – at least for those boosted!
    There are indications that individuals fully vaccinated against the coronavirus, within six months or with the booster, are also protected against the Omicron variant, Health Minister Nitzan Horowitz said Tuesday, after another two cases of individuals infected with the variant were identified, bringing the total to four. “In the coming days we will have more accurate information about the efficacy of the vaccine against Omicron but there is already room for optimism, and there are initial indications that those who are vaccinated with a vaccine STILL valid or with a booster, will also be protected from this variant.” In addition, according to the report, the ability of the variant to infect is higher than Delta but not as much as feared- around 1.3 times higher.
    At the same time, those not inoculated have a 2.4 times greater chances of developing serious symptoms- a significant figure. You can read this and more here: https://jpost.com/health-and-wellness/coronavirus/covid-1st-data-about-vaccine-efficacy-against-omicron-expected-tuesday-687392

    TLDR Get vaccinated, get boosted.

    Looks like fantastic news and a vindication of expediting the booster programme. Fair play to Javid.
    Two cardiologists from Sheba Medical Center were verified as infected with the Omicron variant, a spokesperson for the hospital confirmed.
    He said they were experiencing “very light symptoms.”
    One of the doctors, in his 50s, brought the variant into Israel on return from a medical conference in London.
    When was this chap in London I ask myself? I'll bet it doesn't fit with the original timeframe that this was cooked up in Botswana on Wednesday.
    Makes you wonder doesn't it.
    Not really, because if you ever thought detected in = cooked up in, in the first place, I doubt anything on earth has the power to make you actually think.
    Can I have a translation please.
    You just seem to be a bit off the pace, intellectually speaking. Like saying in 2021 that the discovery of dinosaur fossils makes you wonder about the theory that the world was created in mid October 4004 BC.
    I am glad that I am extremely comfortable in my own intellectual capabilities not to be concerned by a random person off the internet thinks.

    You also seemed to have misunderstood my point, which was I think it is becoming increasingly clear that this variant has been around a fair bit longer than just a few days. In fact we already know this from the confirmed cases. It then makes you wonder, just how long, no more "conspiracy" beyond that.
    But who in the name of God, assuming they can simultaneously walk and chew gum, ever deduced "this was only detected a few days ago, therefore this has only been around for a few days"?
    Next you'll be telling us that when the extremities of a rabbit have a larger angular separation than those of a blue whale, the theory that the rabbit is larger than the whale is not a slam dunk
  • MaxPBMaxPB Posts: 38,853
    moonshine said:

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    How cheap is to sequence a genome now? Did it hit $1000 yet? What’s the explanation for why most countries are not even bothering to try?
    See the reaction to SA being honest.
  • AnabobazinaAnabobazina Posts: 23,486

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    New Zealand
    5.

  • FrancisUrquhartFrancisUrquhart Posts: 82,054
    edited November 2021
    Christ alive Farage love in with the Trumpster is apparently 2hrs.....but it seems the "scoop" is basically he is intending to try and run again.

    I wonder rather watch the complete 9hrs of the Beatles documentary.
  • MaxPB said:

    moonshine said:

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    How cheap is to sequence a genome now? Did it hit $1000 yet? What’s the explanation for why most countries are not even bothering to try?
    See the reaction to SA being honest.
    There's a very good chance it didn't start there....
  • moonshinemoonshine Posts: 5,748
    MaxPB said:

    moonshine said:

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    How cheap is to sequence a genome now? Did it hit $1000 yet? What’s the explanation for why most countries are not even bothering to try?
    See the reaction to SA being honest.
    Credit to Australia. That’s a big percentage of their cases. Most of Europe should be ashamed. Equally dreadfully low number for India. Doesn’t bode well for any hopes of a post covid NATO type organisation against Infectious disease, even putting China to one side.
  • LostPasswordLostPassword Posts: 18,394

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    New Zealand
    5.

    Some of those numbers are weird. Earlier chart had Denmark sequencing a third of their cases, but in this later one they've only done 753 sequences in total? That doesn't add up.
  • geoffwgeoffw Posts: 8,720

    MaxPB said:

    moonshine said:

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    How cheap is to sequence a genome now? Did it hit $1000 yet? What’s the explanation for why most countries are not even bothering to try?
    See the reaction to SA being honest.
    There's a very good chance it didn't start there....
    The BBC is nowadays saying "first identified in SA"
  • ydoethurydoethur Posts: 71,420
    geoffw said:

    MaxPB said:

    moonshine said:

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    How cheap is to sequence a genome now? Did it hit $1000 yet? What’s the explanation for why most countries are not even bothering to try?
    See the reaction to SA being honest.
    There's a very good chance it didn't start there....
    The BBC is nowadays saying "first identified in SA"
    But it's travelled this whole world of ours from Barnsley to Peru...
  • IshmaelZIshmaelZ Posts: 21,830

    MaxPB said:

    moonshine said:

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    How cheap is to sequence a genome now? Did it hit $1000 yet? What’s the explanation for why most countries are not even bothering to try?
    See the reaction to SA being honest.
    There's a very good chance it didn't start there....
    It must be international D'oh! day.
  • Christ alive Farage love in with the Trumpster is apparently 2hrs.....but it seems the "scoop" is basically he is intending to try and run again.

    I wonder rather watch the complete 9hrs of the Beatles documentary.

    I would rather watch paint dry than those two
  • rcs1000rcs1000 Posts: 57,189

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    The UK is head and shoulders ahead of the rest of the world in sequencing. No-one else (with the possible exception of the US) comes close.
  • ydoethurydoethur Posts: 71,420
    And another country goes down the compulsory vaccination route:

    Covid: Greece to fine over-60s who refuse Covid-19 vaccine
    https://www.bbc.co.uk/news/world-europe-59474808

    (Apols if it has already been posted, I haven't time to read full threads atm.)

    €100 per month is serious money in Greece. They must be in a state of near panic.
  • geoffwgeoffw Posts: 8,720
    ydoethur said:

    geoffw said:

    MaxPB said:

    moonshine said:

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    How cheap is to sequence a genome now? Did it hit $1000 yet? What’s the explanation for why most countries are not even bothering to try?
    See the reaction to SA being honest.
    There's a very good chance it didn't start there....
    The BBC is nowadays saying "first identified in SA"
    But it's travelled this whole world of ours from Barnsley to Peru...
    Possibly. But at least they are crediting SA with the identification and not implying that its origin is there.
  • rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    New Zealand
    5.

    Some of those numbers are weird. Earlier chart had Denmark sequencing a third of their cases, but in this later one they've only done 753 sequences in total? That doesn't add up.
    It's the sequences they've uploaded to: https://www.covid19dataportal.org/the-covid-19-data-portal

    They're doing the sequencing, just not sending it to this database.
  • MexicanpeteMexicanpete Posts: 28,374
    isam said:

    isam said:

    isam said:

    ydoethur said:

    kinabalu said:

    kinabalu said:

    kinabalu said:

    MaxPB said:

    kinabalu said:

    TOPPING said:

    kinabalu said:

    For the zillionth time (does this really need repeating??) more regulation is not synonymous with better regulation. It's one of the most bizarre features of people on the Left that they seem to be totally incapable of getting their heads around this simplest of propositions. And I think it's a genuine intellectual failure in them, not just the obvious one of seeking to excuse a Labour Chancellor for the catastrophic dog's breakfast he made of financial regulation.

    Semi agreed. The regime put in place was rubbish and failed but there is no way on this earth that the old one, let alone any the Cons (who were fully signed up to 'light touch') would conceivably have implemented, could have headed off the crash of 08 or mitigated its impact on us to any significant degree.
    There is "the crash of 08" with its attendant CDS and so forth, and there is the first bank panic in the UK for XX years with people queuing round the block to get their money out. The former of course not; the latter, perhaps.
    The business model in question would need to have been prohibited in order to stop that. But the political culture of the time was 'these guys know what they're doing, leave them be, count the tax pounds'. Would this have been different with George Osborne or John McDonnell instead of Gordon Brown as Chancellor? (I now copy your last sentence).
    The Bank of England is still in charge of monitoring bank capital ratios and blocks RBS from buying ABN Amro. The Bank of England tells Northern Rock it's business model is built on sand and to hold 8% capital, not 0%. The Bank of England tells HBOS the same and to hold 8% reserve capital.

    That alone changes the nature and severity of the banking crisis in 08. You want to rewrite history and pretend it was investment banks that failed in the UK, it wasn't, it was standard old retail banks that shat the bed and needed bailing out.

    I still think we should have let all of them go bankrupt and stood behind the depositors. It was a mistake to for the state to step in and socialise losses.
    I'm not rewriting history. You're constructing an alternative history whereby under the 'light touch' laissez faire Tories, the City's reckless exuberance (being kind there) would have been tamed to such an extent that when global money markets had their near fatal seizure we here would have been largely protected. I find this fanciful in the extreme. Also the distinction between retail and investment banks' behaviour isn't a clear one. Eg, a large part of RBS's problem was paying a ludicrous amount for the poison pill that was ABN. It was full of junk. Barclays and the much vaunted Bob Diamond avoided that fate by the sheer dumb luck of being outbid by a bigger and more hubristic fool. Investment banks (and bankers) played a full part in the debacle on both sides of the Atlantic.
    Ask yourself this, why after such a long period of it not happening why did so many banks go bust after Gordon Brown changed the rules?

    Now I've spent the last decade working in banking and financial services regulation/compliance so I'm obviously an ingénue in these matters, so be gentle.
    Because the 08 crash and subsequent markets seizure exposed the fact that the City had long abdicated on risk management in a breathless chase for remuneration and status. Is my answer.

    Unless you're talking about a stream of failures before that?
    That Tory manifesto from 2005 again, in the wake of the pressure from Hannan and others' a year earlier to fully "Icelandise" the UK financial sector :

    "The best guarantee of future prosperity is a dynamic economy. New technology and the speed of global capital flows punish the inflexible and the sluggish. We need to reward risk-taking ...."
    Yep. There is mucho bollocks being talked in places. Brown deserves his big black mark on this - he fell for the myth of City 'flair plus competence' and he WAS the CoE for heavens sake - but there is simply no way it wouldn't have panned out similar or worse under the Cons. But of course we can't prove this. So the claim persists. Grrr.
    A better example might be Black Wednesday. Brown was a full-throated supporter of the ERM long after it had become obvious even to Major and Lamont that we would have to withdraw. But nobody ever holds that against him even though had he been in charge things would have been fifty times worse.

    Similarly it was as well for George Osborne's reputation, such as remains, that he wasn't in charge when Lehmanns went belly up. Mouse in the headlights would describe his demeanour quite well.
    You have perfectly explained why contrary to what BigG and Isam are touting, it matters not a jot if Starmer calls Covid wrong today. It is far more important for Johnson to call it right however.
    It matters in the context of the next GE campaign - The Tories, if Boris is right, can point out they freed us whilst Labour clamoured for lockdown - it is all about the next GE campaign. I was thinking earlier on that pollsters shouldn't ask "How would you vote if there were a General Election tomorrow" but "How would you vote if there were a General Election tomorrow, taking into account there would have had been 2 months campaigning" and "Who do you think will perform better in the Election debates"
    No it doesn't, unless every couple of months between now and the next GE Starmer keeps calling it wrong and Johnson keeps calling it right, or there is indeed an election tomorrow. Besides which Covid will be just one of a number of GE issues for Johnson to call right by then. Oh, and Johnson won't do the debates he will again use a surrogate.
    You think the only political topics people have talked about for the last two years won't have any bearing on the next GE? Fair enough, agree to disagree
    Of course they will, but don't you think the bulk of the vaccine bonus is already baked in for Johnson, there is probably a little more to come from the boosters.

    When the Government's Covid post-mortem analysis is in Johnson's performance report will be mixed to say the least.

    I am also not convinced Johnson getting Christmas right gives him many smartie points, getting it wrong loses lots.

    Starmer's call by contrast is largely irrelevant.
    I am saying it will give the Tories some ammo at the next GE - it is one of the biggest decisions in modern history - whether to impose restrictions of people freedoms or not. If Boris doesn't,and is proven correct, for a second time whilst Sir Keir is haranguing him to, of course the Tories will use it at the next GE, as well as their vaccine successes
    Maybe, but I doubt it will have the net benefit you assume. The context of the too late initial lockdown, the cock up of September 2020 and his failure to save Christmas 2020 will have as much bearing in the medium term as him having saved Christmas 2021, which remains to be seen..

    I may be completely wrong. I have been surprised that vaccinations are the gift that keeps on giving for Johnson. He will undoubtedly get a boost from the boosters too.
  • LeonLeon Posts: 55,390
    Pulpstar said:

    @sailorrooscout
    ·
    1m

    PRELIMINARY DATA but good news for your afternoon! Pfizer vaccine’s is only SLIGHTLY less effective in preventing infection with Omicron than with Delta- 90% as opposed to 95%- while it is AS EFFECTIVE in preventing serious symptoms- around 93% – at least for those boosted!
    There are indications that individuals fully vaccinated against the coronavirus, within six months or with the booster, are also protected against the Omicron variant, Health Minister Nitzan Horowitz said Tuesday, after another two cases of individuals infected with the variant were identified, bringing the total to four. “In the coming days we will have more accurate information about the efficacy of the vaccine against Omicron but there is already room for optimism, and there are initial indications that those who are vaccinated with a vaccine STILL valid or with a booster, will also be protected from this variant.” In addition, according to the report, the ability of the variant to infect is higher than Delta but not as much as feared- around 1.3 times higher.
    At the same time, those not inoculated have a 2.4 times greater chances of developing serious symptoms- a significant figure. You can read this and more here: https://jpost.com/health-and-wellness/coronavirus/covid-1st-data-about-vaccine-efficacy-against-omicron-expected-tuesday-687392

    TLDR Get vaccinated, get boosted.

    What a relief - if it is true. But what a scary number for the unvaxxed. Get yer fucking jab, @Dura_Ace
  • geoffwgeoffw Posts: 8,720
    IshmaelZ said:

    MaxPB said:

    moonshine said:

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    How cheap is to sequence a genome now? Did it hit $1000 yet? What’s the explanation for why most countries are not even bothering to try?
    See the reaction to SA being honest.
    There's a very good chance it didn't start there....
    It must be international D'oh! day.
    St Andrews day, actually.

  • MaxPBMaxPB Posts: 38,853

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    New Zealand
    5.

    Some of those numbers are weird. Earlier chart had Denmark sequencing a third of their cases, but in this later one they've only done 753 sequences in total? That doesn't add up.
    It's the sequences they've uploaded to: https://www.covid19dataportal.org/the-covid-19-data-portal

    They're doing the sequencing, just not sending it to this database.
    Which is really shitty of them, that's a lot of monitoring the world has no visibility on from continental Europe.
  • IshmaelZIshmaelZ Posts: 21,830
    geoffw said:

    IshmaelZ said:

    MaxPB said:

    moonshine said:

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    How cheap is to sequence a genome now? Did it hit $1000 yet? What’s the explanation for why most countries are not even bothering to try?
    See the reaction to SA being honest.
    There's a very good chance it didn't start there....
    It must be international D'oh! day.
    St Andrews day, actually.

    Patron saint of d'ohness.
  • LeonLeon Posts: 55,390
    IanB2 said:

    isam said:

    moonshine said:

    SA:

    UPDATE: A total of 42,664 tests were conducted in the last 24hrs, with 4,373 new cases, which represents a 10.2% positivity rate. A further 21#COVID19 related deaths have been reported, bringing total fatalities to 89,843 to date. See more here: https://nicd.ac.za/latest-confirmed-cases-of-covid-19-in-south-africa-30-november-2021/

    https://twitter.com/nicd_sa/status/1465727369151459329

    Maintaining a positivity rate that would make quite a few Western European countries blush...

    Not testing much are they and still their positivity rate is only double ours.
    And substantially lower than Germany (17.3%), Belgium (15.7%) Switzerland (14.8%) or the Netherlands (13.9%), let alone Poland (24.6%).

    There is every possibility that Omicron didn't start in SA but was first identified there.
    Starting to look like that might be the case. The Scottish cases had no link to southern Africa, apparently.
    Imagine the mild cold that everyone I know has had for a fortnight was Omicron!
    Leon will be along with a similar anecdote in a mo.

    I can do better than that. I actually have a weird minor cold RIGHT NOW
  • MaxPBMaxPB Posts: 38,853
    Leon said:

    Pulpstar said:

    @sailorrooscout
    ·
    1m

    PRELIMINARY DATA but good news for your afternoon! Pfizer vaccine’s is only SLIGHTLY less effective in preventing infection with Omicron than with Delta- 90% as opposed to 95%- while it is AS EFFECTIVE in preventing serious symptoms- around 93% – at least for those boosted!
    There are indications that individuals fully vaccinated against the coronavirus, within six months or with the booster, are also protected against the Omicron variant, Health Minister Nitzan Horowitz said Tuesday, after another two cases of individuals infected with the variant were identified, bringing the total to four. “In the coming days we will have more accurate information about the efficacy of the vaccine against Omicron but there is already room for optimism, and there are initial indications that those who are vaccinated with a vaccine STILL valid or with a booster, will also be protected from this variant.” In addition, according to the report, the ability of the variant to infect is higher than Delta but not as much as feared- around 1.3 times higher.
    At the same time, those not inoculated have a 2.4 times greater chances of developing serious symptoms- a significant figure. You can read this and more here: https://jpost.com/health-and-wellness/coronavirus/covid-1st-data-about-vaccine-efficacy-against-omicron-expected-tuesday-687392

    TLDR Get vaccinated, get boosted.

    What a relief - if it is true. But what a scary number for the unvaxxed. Get yer fucking jab, @Dura_Ace
    Yes, that 2.4x figure is definitely pretty bloody scary, it also looks like acquired immunity is only diluted by a small amount so people who got delta this summer should also be fine if this data is good.
  • ydoethurydoethur Posts: 71,420
    geoffw said:

    ydoethur said:

    geoffw said:

    MaxPB said:

    moonshine said:

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    How cheap is to sequence a genome now? Did it hit $1000 yet? What’s the explanation for why most countries are not even bothering to try?
    See the reaction to SA being honest.
    There's a very good chance it didn't start there....
    The BBC is nowadays saying "first identified in SA"
    But it's travelled this whole world of ours from Barnsley to Peru...
    Possibly. But at least they are crediting SA with the identification and not implying that its origin is there.
    And another awesome cultural reference goes unremarked...
  • AnabobazinaAnabobazina Posts: 23,486
    Leon said:

    IanB2 said:

    isam said:

    moonshine said:

    SA:

    UPDATE: A total of 42,664 tests were conducted in the last 24hrs, with 4,373 new cases, which represents a 10.2% positivity rate. A further 21#COVID19 related deaths have been reported, bringing total fatalities to 89,843 to date. See more here: https://nicd.ac.za/latest-confirmed-cases-of-covid-19-in-south-africa-30-november-2021/

    https://twitter.com/nicd_sa/status/1465727369151459329

    Maintaining a positivity rate that would make quite a few Western European countries blush...

    Not testing much are they and still their positivity rate is only double ours.
    And substantially lower than Germany (17.3%), Belgium (15.7%) Switzerland (14.8%) or the Netherlands (13.9%), let alone Poland (24.6%).

    There is every possibility that Omicron didn't start in SA but was first identified there.
    Starting to look like that might be the case. The Scottish cases had no link to southern Africa, apparently.
    Imagine the mild cold that everyone I know has had for a fortnight was Omicron!
    Leon will be along with a similar anecdote in a mo.

    I can do better than that. I actually have a weird minor cold RIGHT NOW
    Omnicron+ no doubt.
  • LeonLeon Posts: 55,390
    glw said:

    Data isn't from Israel, its from South Africa. It has been passed to the Israeli's to look at, but somebody leaks it to a media channel. Nothing is confirmed yet.

    Yep, but summarising so far about 30% more transmissible, up to twice the reinfection rate, about the same moribidity for the vaccinated, but about double for the unvaccinated. No aspect here is good news, this is worse or equal to Delta across the board. The only saving grace is that vaccines still seem to work well enough to keep most people out of hospital. Of course the sample size here is so small that these figures are only preliminary and likely to shift a fair bit as more data comes in and time passes.

    I HATE TO BRAG, but this is uncannily close to my ‘official’ predictions the other night

    Somewhat more transmissible, about as bad as Delta for severity, not a major problem for the vaxxed, shit for the unvaxxed
  • moonshinemoonshine Posts: 5,748
    Leon said:

    Pulpstar said:

    @sailorrooscout
    ·
    1m

    PRELIMINARY DATA but good news for your afternoon! Pfizer vaccine’s is only SLIGHTLY less effective in preventing infection with Omicron than with Delta- 90% as opposed to 95%- while it is AS EFFECTIVE in preventing serious symptoms- around 93% – at least for those boosted!
    There are indications that individuals fully vaccinated against the coronavirus, within six months or with the booster, are also protected against the Omicron variant, Health Minister Nitzan Horowitz said Tuesday, after another two cases of individuals infected with the variant were identified, bringing the total to four. “In the coming days we will have more accurate information about the efficacy of the vaccine against Omicron but there is already room for optimism, and there are initial indications that those who are vaccinated with a vaccine STILL valid or with a booster, will also be protected from this variant.” In addition, according to the report, the ability of the variant to infect is higher than Delta but not as much as feared- around 1.3 times higher.
    At the same time, those not inoculated have a 2.4 times greater chances of developing serious symptoms- a significant figure. You can read this and more here: https://jpost.com/health-and-wellness/coronavirus/covid-1st-data-about-vaccine-efficacy-against-omicron-expected-tuesday-687392

    TLDR Get vaccinated, get boosted.

    What a relief - if it is true. But what a scary number for the unvaxxed. Get yer fucking jab, @Dura_Ace
    Maybe we could strike a bargain with Dura. If he gets his jab, we’ll see how many people here we can get to go meatless the day after.
  • Leon said:

    IanB2 said:

    isam said:

    moonshine said:

    SA:

    UPDATE: A total of 42,664 tests were conducted in the last 24hrs, with 4,373 new cases, which represents a 10.2% positivity rate. A further 21#COVID19 related deaths have been reported, bringing total fatalities to 89,843 to date. See more here: https://nicd.ac.za/latest-confirmed-cases-of-covid-19-in-south-africa-30-november-2021/

    https://twitter.com/nicd_sa/status/1465727369151459329

    Maintaining a positivity rate that would make quite a few Western European countries blush...

    Not testing much are they and still their positivity rate is only double ours.
    And substantially lower than Germany (17.3%), Belgium (15.7%) Switzerland (14.8%) or the Netherlands (13.9%), let alone Poland (24.6%).

    There is every possibility that Omicron didn't start in SA but was first identified there.
    Starting to look like that might be the case. The Scottish cases had no link to southern Africa, apparently.
    Imagine the mild cold that everyone I know has had for a fortnight was Omicron!
    Leon will be along with a similar anecdote in a mo.

    I can do better than that. I actually have a weird minor cold RIGHT NOW
    You better do 10 days isolation then....
  • geoffwgeoffw Posts: 8,720
    ydoethur said:

    geoffw said:

    ydoethur said:

    geoffw said:

    MaxPB said:

    moonshine said:

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    How cheap is to sequence a genome now? Did it hit $1000 yet? What’s the explanation for why most countries are not even bothering to try?
    See the reaction to SA being honest.
    There's a very good chance it didn't start there....
    The BBC is nowadays saying "first identified in SA"
    But it's travelled this whole world of ours from Barnsley to Peru...
    Possibly. But at least they are crediting SA with the identification and not implying that its origin is there.
    And another awesome cultural reference goes unremarked...
    Paddington Bear indeed, very awesome.

  • LostPasswordLostPassword Posts: 18,394
    edited November 2021

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    New Zealand
    5.

    Some of those numbers are weird. Earlier chart had Denmark sequencing a third of their cases, but in this later one they've only done 753 sequences in total? That doesn't add up.
    It's the sequences they've uploaded to: https://www.covid19dataportal.org/the-covid-19-data-portal

    They're doing the sequencing, just not sending it to this database.
    Bizarrely the portal is [part] funded by the EU, and yet seems to be really poorly supported by most EU countries.
  • NigelbNigelb Posts: 71,121
    moonshine said:

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    How cheap is to sequence a genome now? Did it hit $1000 yet? What’s the explanation for why most countries are not even bothering to try?
    For a virus, probably a lot less than that, particularly if using nanopore sequencing, and if it’s a regular workflow.
  • Why is Dura refusing the Bill Gates sponsored microchipping?
  • LeonLeon Posts: 55,390
    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    It is odd. My guess: China is sequencing all of Cambodia’s data, because China wants to know more about Covid, but China has so few cases of its own. Cambodia is a vassal state of China, these days
  • Why is Dura refusing the Bill Gates sponsored microchipping?

    Tested on animals.
  • LeonLeon Posts: 55,390

    Why is Dura refusing the Bill Gates sponsored microchipping?

    Tested on animals. He’s British Drag Racing Green
  • geoffwgeoffw Posts: 8,720
    Leon said:

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    It is odd. My guess: China is sequencing all of Cambodia’s data, because China wants to know more about Covid, but China has so few cases of its own. Cambodia is a vassal state of China, these days
    Quite a lot of bats with coronas in Cambodia, some very much like CV-19.

  • NickPalmerNickPalmer Posts: 21,530
    MaxPB said:

    Eabhal said:

    What's the play if Omicron has no vaccine escape but is absolutely devastating to the unvaxxed?

    An exceptionally tough decision for the PM. An NHS overrun with anti-vaxxers hurts all of us, so do we put then at the back of the queue for treatment? Or do we have to accept a lockdown?

    We don't really have enough people in the non-immune categories for that to happen. The LSHTM model was quite prescient in that it predicted what hospitalisations would look like if everyone in the country was exposed to the virus tomorrow, it works out to about 40k people hospitalised here. It's not an earth shattering figure.
    Can you talk us through the numbers, or give a link? The Uk population is about 70 million, of whom 70% are fully vaccinated. Assume that nobody who is fully vaccinated catches a case of Covid serious enough to be hospitalised. That leaves 24 million people who are not fully vaccinated yet. You say that if they were all exposed to the virus tomorrow, less than 0.2% would be hospitalised? That would be excellent news, but it doesn't sound right.
  • FrancisUrquhartFrancisUrquhart Posts: 82,054
    edited November 2021
    Leon said:

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    It is odd. My guess: China is sequencing all of Cambodia’s data, because China wants to know more about Covid, but China has so few cases of its own. Cambodia is a vassal state of China, these days
    I think we have discussed on here the dodgy nature of all the football shirt sponsors of betting companies we have never heard of, which are really just for the Chinese market. I knew they were mostly run out of the Philippines, what I didn't realise is because of a deal they did with China in regards allowing skilled labour in.

    China initially thought this was another good move to spread their influence, except now 100-150k Chinese nationals are there in order to facilitate the illegal gambling of Chinese nationals who are in China.
  • Why is Dura refusing the Bill Gates sponsored microchipping?

    Durex Ace burns a lot of rubbers :lol:
  • LeonLeon Posts: 55,390
    moonshine said:

    kinabalu said:

    moonshine said:

    kinabalu said:

    moonshine said:

    kinabalu said:

    kinabalu said:

    kinabalu said:

    MaxPB said:

    kinabalu said:

    TOPPING said:

    kinabalu said:

    For the zillionth time (does this really need repeating??) more regulation is not synonymous with better regulation. It's one of the most bizarre features of people on the Left that they seem to be totally incapable of getting their heads around this simplest of propositions. And I think it's a genuine intellectual failure in them, not just the obvious one of seeking to excuse a Labour Chancellor for the catastrophic dog's breakfast he made of financial regulation.

    Semi agreed. The regime put in place was rubbish and failed but there is no way on this earth that the old one, let alone any the Cons (who were fully signed up to 'light touch') would conceivably have implemented, could have headed off the crash of 08 or mitigated its impact on us to any significant degree.
    There is "the crash of 08" with its attendant CDS and so forth, and there is the first bank panic in the UK for XX years with people queuing round the block to get their money out. The former of course not; the latter, perhaps.
    The business model in question would need to have been prohibited in order to stop that. But the political culture of the time was 'these guys know what they're doing, leave them be, count the tax pounds'. Would this have been different with George Osborne or John McDonnell instead of Gordon Brown as Chancellor? (I now copy your last sentence).
    The Bank of England is still in charge of monitoring bank capital ratios and blocks RBS from buying ABN Amro. The Bank of England tells Northern Rock it's business model is built on sand and to hold 8% capital, not 0%. The Bank of England tells HBOS the same and to hold 8% reserve capital.

    That alone changes the nature and severity of the banking crisis in 08. You want to rewrite history and pretend it was investment banks that failed in the UK, it wasn't, it was standard old retail banks that shat the bed and needed bailing out.

    I still think we should have let all of them go bankrupt and stood behind the depositors. It was a mistake to for the state to step in and socialise losses.
    I'm not rewriting history. You're constructing an alternative history whereby under the 'light touch' laissez faire Tories, the City's reckless exuberance (being kind there) would have been tamed to such an extent that when global money markets had their near fatal seizure we here would have been largely protected. I find this fanciful in the extreme. Also the distinction between retail and investment banks' behaviour isn't a clear one. Eg, a large part of RBS's problem was paying a ludicrous amount for the poison pill that was ABN. It was full of junk. Barclays and the much vaunted Bob Diamond avoided that fate by the sheer dumb luck of being outbid by a bigger and more hubristic fool. Investment banks (and bankers) played a full part in the debacle on both sides of the Atlantic.
    Ask yourself this, why after such a long period of it not happening why did so many banks go bust after Gordon Brown changed the rules?

    Now I've spent the last decade working in banking and financial services regulation/compliance so I'm obviously an ingénue in these matters, so be gentle.
    Because the 08 crash and subsequent markets seizure exposed the fact that the City had long abdicated on risk management in a breathless chase for remuneration and status. Is my answer.

    Unless you're talking about a stream of failures before that?
    That Tory manifesto from 2005 again, in the wake of the pressure from Hannan and others' a year earlier to fully "Icelandise" the UK financial sector :

    "The best guarantee of future prosperity is a dynamic economy. New technology and the speed of global capital flows punish the inflexible and the sluggish. We need to reward risk-taking ...."
    Yep. There is mucho bollocks being talked in places. Brown deserves his big black mark on this - he fell for the myth of City 'flair plus competence' and he WAS the CoE for heavens sake - but there is simply no way it wouldn't have panned out similar or worse under the Cons. But of course we can't prove this. So the claim persists. Grrr.
    Before Northern Rock, there was 150 years since the last British bank run. A period where the Conservative Party held office the majority of the time. But don’t let that get in the way of your nonsense.
    Suggest you get back to your specialist field of flying saucers.
    You’re a bit touchy.
    :smile: - You can't go saying I'm talking nonsense when you clearly haven't the first clue about it!

    Do I ever tell you you're talking nonsense on the saucers? No, I don't. I read and have a think.
    Perhaps one day I’ll meet you IRL and you can thereafter review my cv and decide if I am more or less qualified than you to talk about risk within the banking system.

    Also on UAPs, you are much like most people and have clearly still done no serious thinking or reading on the recent public discourse in the US. If you had, you would be thinking about it with a more open mind and frankly be amused that some people still think it a topic worthy of stigma or ridicule, bearing in mind the comments even in the last month by for example the serving Administrator of NASA or Michio Kaku, cofounder of string theory.

    It’s taken @kinabalu about 18 months to accept the premise that Lab Leak is plausible. He is a reasonably intelligent guy (but no genius), with a fantastically narrow and settled mind. You have to PRISE it open. I’d give up on UAPs if I were you
  • CookieCookie Posts: 13,810
    moonshine said:

    Leon said:

    Pulpstar said:

    @sailorrooscout
    ·
    1m

    PRELIMINARY DATA but good news for your afternoon! Pfizer vaccine’s is only SLIGHTLY less effective in preventing infection with Omicron than with Delta- 90% as opposed to 95%- while it is AS EFFECTIVE in preventing serious symptoms- around 93% – at least for those boosted!
    There are indications that individuals fully vaccinated against the coronavirus, within six months or with the booster, are also protected against the Omicron variant, Health Minister Nitzan Horowitz said Tuesday, after another two cases of individuals infected with the variant were identified, bringing the total to four. “In the coming days we will have more accurate information about the efficacy of the vaccine against Omicron but there is already room for optimism, and there are initial indications that those who are vaccinated with a vaccine STILL valid or with a booster, will also be protected from this variant.” In addition, according to the report, the ability of the variant to infect is higher than Delta but not as much as feared- around 1.3 times higher.
    At the same time, those not inoculated have a 2.4 times greater chances of developing serious symptoms- a significant figure. You can read this and more here: https://jpost.com/health-and-wellness/coronavirus/covid-1st-data-about-vaccine-efficacy-against-omicron-expected-tuesday-687392

    TLDR Get vaccinated, get boosted.

    What a relief - if it is true. But what a scary number for the unvaxxed. Get yer fucking jab, @Dura_Ace
    Maybe we could strike a bargain with Dura. If he gets his jab, we’ll see how many people here we can get to go meatless the day after.
    I'm in. I'll do three days meat free to keep the cantankerous old fucker alive.
  • Pulpstar said:

    I think it's highly likely Omicron was brewed up in an immunocompromised individual from a richer country. Probably on convalescent plasma and whatnot.


    And the Saffas have got the blame for it – because they identified it!
    He who smelt it dealt it, the eternal law.
  • turbotubbsturbotubbs Posts: 17,409

    MaxPB said:

    Eabhal said:

    What's the play if Omicron has no vaccine escape but is absolutely devastating to the unvaxxed?

    An exceptionally tough decision for the PM. An NHS overrun with anti-vaxxers hurts all of us, so do we put then at the back of the queue for treatment? Or do we have to accept a lockdown?

    We don't really have enough people in the non-immune categories for that to happen. The LSHTM model was quite prescient in that it predicted what hospitalisations would look like if everyone in the country was exposed to the virus tomorrow, it works out to about 40k people hospitalised here. It's not an earth shattering figure.
    Can you talk us through the numbers, or give a link? The Uk population is about 70 million, of whom 70% are fully vaccinated. Assume that nobody who is fully vaccinated catches a case of Covid serious enough to be hospitalised. That leaves 24 million people who are not fully vaccinated yet. You say that if they were all exposed to the virus tomorrow, less than 0.2% would be hospitalised? That would be excellent news, but it doesn't sound right.
    No data, but an awful lot have had Covid too. Greater than 90% show antibodies.
  • FrancisUrquhartFrancisUrquhart Posts: 82,054
    edited November 2021

    Why is Dura refusing the Bill Gates sponsored microchipping?

    Tested on animals.
    Wasn't it reported the other day some youngish guy who was a vegan and objected for that very reason died after catching COVID.....his dying words, he wished he had got it.
  • Why is Dura refusing the Bill Gates sponsored microchipping?

    Tested on animals.
    Wasn't it reported the other day some youngish guy who was a vegan and objected for that very reason died after catching COVID.....his dying words, he wished he had got it.
    Yup.

    https://www.manchestereveningnews.co.uk/news/uk-news/vegan-who-refused-vaccine-because-22306094
  • LeonLeon Posts: 55,390
    Cookie said:

    moonshine said:

    Leon said:

    Pulpstar said:

    @sailorrooscout
    ·
    1m

    PRELIMINARY DATA but good news for your afternoon! Pfizer vaccine’s is only SLIGHTLY less effective in preventing infection with Omicron than with Delta- 90% as opposed to 95%- while it is AS EFFECTIVE in preventing serious symptoms- around 93% – at least for those boosted!
    There are indications that individuals fully vaccinated against the coronavirus, within six months or with the booster, are also protected against the Omicron variant, Health Minister Nitzan Horowitz said Tuesday, after another two cases of individuals infected with the variant were identified, bringing the total to four. “In the coming days we will have more accurate information about the efficacy of the vaccine against Omicron but there is already room for optimism, and there are initial indications that those who are vaccinated with a vaccine STILL valid or with a booster, will also be protected from this variant.” In addition, according to the report, the ability of the variant to infect is higher than Delta but not as much as feared- around 1.3 times higher.
    At the same time, those not inoculated have a 2.4 times greater chances of developing serious symptoms- a significant figure. You can read this and more here: https://jpost.com/health-and-wellness/coronavirus/covid-1st-data-about-vaccine-efficacy-against-omicron-expected-tuesday-687392

    TLDR Get vaccinated, get boosted.

    What a relief - if it is true. But what a scary number for the unvaxxed. Get yer fucking jab, @Dura_Ace
    Maybe we could strike a bargain with Dura. If he gets his jab, we’ll see how many people here we can get to go meatless the day after.
    I'm in. I'll do three days meat free to keep the cantankerous old fucker alive.
    Yep, me too. 3 days without meat. Pescatarian allowed?

    In return Dura has to get the jab. He can save his life while saving about 100 animals and maybe turning 2 of us veggie, if we like the experience. Win win
  • NigelbNigelb Posts: 71,121
    geoffw said:

    Leon said:

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    It is odd. My guess: China is sequencing all of Cambodia’s data, because China wants to know more about Covid, but China has so few cases of its own. Cambodia is a vassal state of China, these days
    Quite a lot of bats with coronas in Cambodia, some very much like CV-19.

    And Laos, especially.
  • MaxPBMaxPB Posts: 38,853
    One thing that was a bit puzzling was the rise in cases after half term, the R value had fallen to a level that should have allowed for schools to reopen without seeing any real rise in cases with Delta, with Omicron having a 30% transmission advantage over Delta we may actually already be in the middle of our Omicron wave but we haven't necessarily been looking for a new variant. Again, if we look at the latest slowish drop off that also lines up with a higher transmissibility variant pushing the herd immunity threshold up to ~93% from ~90%.

    I wouldn't be surprised if when we go back and sequence the ONS samples there's a significant proportion with S-gene dropout for Omicron that may have been put down to Alpha.

    It also could explain the very, very rapid rise in countries with overall immunity rates under 80% in Europe. Hopefully the government is doing random sampling of swabs from the beginning of November to now for S-gene dropout and then going back and looking at case outcomes for those people who tested positive with vaccine and prior acquired immunity status if it's known.
  • ydoethurydoethur Posts: 71,420
    geoffw said:

    ydoethur said:

    geoffw said:

    ydoethur said:

    geoffw said:

    MaxPB said:

    moonshine said:

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    How cheap is to sequence a genome now? Did it hit $1000 yet? What’s the explanation for why most countries are not even bothering to try?
    See the reaction to SA being honest.
    There's a very good chance it didn't start there....
    The BBC is nowadays saying "first identified in SA"
    But it's travelled this whole world of ours from Barnsley to Peru...
    Possibly. But at least they are crediting SA with the identification and not implying that its origin is there.
    And another awesome cultural reference goes unremarked...
    Paddington Bear indeed, very awesome.

    The fact that I know Spitting Image songs and others don't is just ma maladie.
  • LostPasswordLostPassword Posts: 18,394

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    New Zealand
    5.

    Some of those numbers are weird. Earlier chart had Denmark sequencing a third of their cases, but in this later one they've only done 753 sequences in total? That doesn't add up.
    It's the sequences they've uploaded to: https://www.covid19dataportal.org/the-covid-19-data-portal

    They're doing the sequencing, just not sending it to this database.
    Bizarrely the portal is [part] funded by the EU, and yet seems to be really poorly supported by most EU countries.
    European countries looks a bit better (Denmark a lot better) in terms of sequences submitted to this other portal. https://www.gisaid.org/index.php?id=208
  • LostPasswordLostPassword Posts: 18,394

    MaxPB said:

    Eabhal said:

    What's the play if Omicron has no vaccine escape but is absolutely devastating to the unvaxxed?

    An exceptionally tough decision for the PM. An NHS overrun with anti-vaxxers hurts all of us, so do we put then at the back of the queue for treatment? Or do we have to accept a lockdown?

    We don't really have enough people in the non-immune categories for that to happen. The LSHTM model was quite prescient in that it predicted what hospitalisations would look like if everyone in the country was exposed to the virus tomorrow, it works out to about 40k people hospitalised here. It's not an earth shattering figure.
    Can you talk us through the numbers, or give a link? The Uk population is about 70 million, of whom 70% are fully vaccinated. Assume that nobody who is fully vaccinated catches a case of Covid serious enough to be hospitalised. That leaves 24 million people who are not fully vaccinated yet. You say that if they were all exposed to the virus tomorrow, less than 0.2% would be hospitalised? That would be excellent news, but it doesn't sound right.
    No data, but an awful lot have had Covid too. Greater than 90% show antibodies.
    Our vaccinations skew strongly to the older, more vulnerable age groups. That makes a big difference too.

    Max gave the link to someone else recently. Probably quite easy to find if you go through his recent comments.
  • IshmaelZIshmaelZ Posts: 21,830
    Leon said:

    moonshine said:

    kinabalu said:

    moonshine said:

    kinabalu said:

    moonshine said:

    kinabalu said:

    kinabalu said:

    kinabalu said:

    MaxPB said:

    kinabalu said:

    TOPPING said:

    kinabalu said:

    For the zillionth time (does this really need repeating??) more regulation is not synonymous with better regulation. It's one of the most bizarre features of people on the Left that they seem to be totally incapable of getting their heads around this simplest of propositions. And I think it's a genuine intellectual failure in them, not just the obvious one of seeking to excuse a Labour Chancellor for the catastrophic dog's breakfast he made of financial regulation.

    Semi agreed. The regime put in place was rubbish and failed but there is no way on this earth that the old one, let alone any the Cons (who were fully signed up to 'light touch') would conceivably have implemented, could have headed off the crash of 08 or mitigated its impact on us to any significant degree.
    There is "the crash of 08" with its attendant CDS and so forth, and there is the first bank panic in the UK for XX years with people queuing round the block to get their money out. The former of course not; the latter, perhaps.
    The business model in question would need to have been prohibited in order to stop that. But the political culture of the time was 'these guys know what they're doing, leave them be, count the tax pounds'. Would this have been different with George Osborne or John McDonnell instead of Gordon Brown as Chancellor? (I now copy your last sentence).
    The Bank of England is still in charge of monitoring bank capital ratios and blocks RBS from buying ABN Amro. The Bank of England tells Northern Rock it's business model is built on sand and to hold 8% capital, not 0%. The Bank of England tells HBOS the same and to hold 8% reserve capital.

    That alone changes the nature and severity of the banking crisis in 08. You want to rewrite history and pretend it was investment banks that failed in the UK, it wasn't, it was standard old retail banks that shat the bed and needed bailing out.

    I still think we should have let all of them go bankrupt and stood behind the depositors. It was a mistake to for the state to step in and socialise losses.
    I'm not rewriting history. You're constructing an alternative history whereby under the 'light touch' laissez faire Tories, the City's reckless exuberance (being kind there) would have been tamed to such an extent that when global money markets had their near fatal seizure we here would have been largely protected. I find this fanciful in the extreme. Also the distinction between retail and investment banks' behaviour isn't a clear one. Eg, a large part of RBS's problem was paying a ludicrous amount for the poison pill that was ABN. It was full of junk. Barclays and the much vaunted Bob Diamond avoided that fate by the sheer dumb luck of being outbid by a bigger and more hubristic fool. Investment banks (and bankers) played a full part in the debacle on both sides of the Atlantic.
    Ask yourself this, why after such a long period of it not happening why did so many banks go bust after Gordon Brown changed the rules?

    Now I've spent the last decade working in banking and financial services regulation/compliance so I'm obviously an ingénue in these matters, so be gentle.
    Because the 08 crash and subsequent markets seizure exposed the fact that the City had long abdicated on risk management in a breathless chase for remuneration and status. Is my answer.

    Unless you're talking about a stream of failures before that?
    That Tory manifesto from 2005 again, in the wake of the pressure from Hannan and others' a year earlier to fully "Icelandise" the UK financial sector :

    "The best guarantee of future prosperity is a dynamic economy. New technology and the speed of global capital flows punish the inflexible and the sluggish. We need to reward risk-taking ...."
    Yep. There is mucho bollocks being talked in places. Brown deserves his big black mark on this - he fell for the myth of City 'flair plus competence' and he WAS the CoE for heavens sake - but there is simply no way it wouldn't have panned out similar or worse under the Cons. But of course we can't prove this. So the claim persists. Grrr.
    Before Northern Rock, there was 150 years since the last British bank run. A period where the Conservative Party held office the majority of the time. But don’t let that get in the way of your nonsense.
    Suggest you get back to your specialist field of flying saucers.
    You’re a bit touchy.
    :smile: - You can't go saying I'm talking nonsense when you clearly haven't the first clue about it!

    Do I ever tell you you're talking nonsense on the saucers? No, I don't. I read and have a think.
    Perhaps one day I’ll meet you IRL and you can thereafter review my cv and decide if I am more or less qualified than you to talk about risk within the banking system.

    Also on UAPs, you are much like most people and have clearly still done no serious thinking or reading on the recent public discourse in the US. If you had, you would be thinking about it with a more open mind and frankly be amused that some people still think it a topic worthy of stigma or ridicule, bearing in mind the comments even in the last month by for example the serving Administrator of NASA or Michio Kaku, cofounder of string theory.

    It’s taken @kinabalu about 18 months to accept the premise that Lab Leak is plausible. He is a reasonably intelligent guy (but no genius), with a fantastically narrow and settled mind. You have to PRISE it open. I’d give up on UAPs if I were you
    The thing about UAPs is, so what? There is no doubt that there is weird and inexplicable shit going on, but what are we meant to do about it? Assume an Independence Day type alien megaship parks itself in geostationary orbit, and just sits there, what would we do about it? We'd wet our knickers about it and have experts giving it large on the telly about it for 6 months, but when there's no more to say, or do, about it, we'd just crack on with normal life. It's an axiom of advertising that you end up telling your target audience what to do next. UAP fanbois please note.
  • TimSTimS Posts: 12,999
    Maybe my maths is wrong here but:

    They say breakthrough infections in those previously infected are twice the rate as for Delta (bad)

    But for the fully vaccinated the efficacy goes down just from 95 to 90% (good).

    But isn’t that vaccine data equivalent to a doubling of breakthrough risk (10% vs 5%)?

    Still pretty decent data to be honest, because both numbers suggest immune escape isn’t that great.
  • dixiedeandixiedean Posts: 29,409
    Government plans for football "Maoist".

    https://www.bbc.co.uk/sport/football/59481154

    Which means kit clashes for one thing.
    Mo Salah knows a thing about to the Great Leap Forward in the penalty area.
  • dixiedeandixiedean Posts: 29,409

    Why is Dura refusing the Bill Gates sponsored microchipping?

    Tested on animals.
    Wasn't it reported the other day some youngish guy who was a vegan and objected for that very reason died after catching COVID.....his dying words, he wished he had got it.
    Yup.

    https://www.manchestereveningnews.co.uk/news/uk-news/vegan-who-refused-vaccine-because-22306094
    Know plenty vegans who've had it, mind
  • FrancisUrquhartFrancisUrquhart Posts: 82,054
    edited November 2021
    dixiedean said:

    Why is Dura refusing the Bill Gates sponsored microchipping?

    Tested on animals.
    Wasn't it reported the other day some youngish guy who was a vegan and objected for that very reason died after catching COVID.....his dying words, he wished he had got it.
    Yup.

    https://www.manchestereveningnews.co.uk/news/uk-news/vegan-who-refused-vaccine-because-22306094
    Know plenty vegans who've had it, mind
    I presume if you take this to the nth degree, I would have thought basically every modern medicine has been tested on animals at some point or involves compounds that have been, no?
  • MaxPB said:

    Eabhal said:

    What's the play if Omicron has no vaccine escape but is absolutely devastating to the unvaxxed?

    An exceptionally tough decision for the PM. An NHS overrun with anti-vaxxers hurts all of us, so do we put then at the back of the queue for treatment? Or do we have to accept a lockdown?

    We don't really have enough people in the non-immune categories for that to happen. The LSHTM model was quite prescient in that it predicted what hospitalisations would look like if everyone in the country was exposed to the virus tomorrow, it works out to about 40k people hospitalised here. It's not an earth shattering figure.
    Can you talk us through the numbers, or give a link? The Uk population is about 70 million, of whom 70% are fully vaccinated. Assume that nobody who is fully vaccinated catches a case of Covid serious enough to be hospitalised. That leaves 24 million people who are not fully vaccinated yet. You say that if they were all exposed to the virus tomorrow, less than 0.2% would be hospitalised? That would be excellent news, but it doesn't sound right.
    Well for a start how many of those 24 million are children who will not get adverse symptom? According to the ONS 20% of the population (which they have as 68 million) is under 16. That is around 13 million or so of the 22 million. So you are looking at around 11 million unvaccinated. And how many of those 11 million have had covid already? The numbers start to decline rapidly when you look at the reasonable exclusions.
  • LeonLeon Posts: 55,390
    IshmaelZ said:

    Leon said:

    moonshine said:

    kinabalu said:

    moonshine said:

    kinabalu said:

    moonshine said:

    kinabalu said:

    kinabalu said:

    kinabalu said:

    MaxPB said:

    kinabalu said:

    TOPPING said:

    kinabalu said:

    For the zillionth time (does this really need repeating??) more regulation is not synonymous with better regulation. It's one of the most bizarre features of people on the Left that they seem to be totally incapable of getting their heads around this simplest of propositions. And I think it's a genuine intellectual failure in them, not just the obvious one of seeking to excuse a Labour Chancellor for the catastrophic dog's breakfast he made of financial regulation.

    Semi agreed. The regime put in place was rubbish and failed but there is no way on this earth that the old one, let alone any the Cons (who were fully signed up to 'light touch') would conceivably have implemented, could have headed off the crash of 08 or mitigated its impact on us to any significant degree.
    There is "the crash of 08" with its attendant CDS and so forth, and there is the first bank panic in the UK for XX years with people queuing round the block to get their money out. The former of course not; the latter, perhaps.
    The business model in question would need to have been prohibited in order to stop that. But the political culture of the time was 'these guys know what they're doing, leave them be, count the tax pounds'. Would this have been different with George Osborne or John McDonnell instead of Gordon Brown as Chancellor? (I now copy your last sentence).
    The Bank of England is still in charge of monitoring bank capital ratios and blocks RBS from buying ABN Amro. The Bank of England tells Northern Rock it's business model is built on sand and to hold 8% capital, not 0%. The Bank of England tells HBOS the same and to hold 8% reserve capital.

    That alone changes the nature and severity of the banking crisis in 08. You want to rewrite history and pretend it was investment banks that failed in the UK, it wasn't, it was standard old retail banks that shat the bed and needed bailing out.

    I still think we should have let all of them go bankrupt and stood behind the depositors. It was a mistake to for the state to step in and socialise losses.
    I'm not rewriting history. You're constructing an alternative history whereby under the 'light touch' laissez faire Tories, the City's reckless exuberance (being kind there) would have been tamed to such an extent that when global money markets had their near fatal seizure we here would have been largely protected. I find this fanciful in the extreme. Also the distinction between retail and investment banks' behaviour isn't a clear one. Eg, a large part of RBS's problem was paying a ludicrous amount for the poison pill that was ABN. It was full of junk. Barclays and the much vaunted Bob Diamond avoided that fate by the sheer dumb luck of being outbid by a bigger and more hubristic fool. Investment banks (and bankers) played a full part in the debacle on both sides of the Atlantic.
    Ask yourself this, why after such a long period of it not happening why did so many banks go bust after Gordon Brown changed the rules?

    Now I've spent the last decade working in banking and financial services regulation/compliance so I'm obviously an ingénue in these matters, so be gentle.
    Because the 08 crash and subsequent markets seizure exposed the fact that the City had long abdicated on risk management in a breathless chase for remuneration and status. Is my answer.

    Unless you're talking about a stream of failures before that?
    That Tory manifesto from 2005 again, in the wake of the pressure from Hannan and others' a year earlier to fully "Icelandise" the UK financial sector :

    "The best guarantee of future prosperity is a dynamic economy. New technology and the speed of global capital flows punish the inflexible and the sluggish. We need to reward risk-taking ...."
    Yep. There is mucho bollocks being talked in places. Brown deserves his big black mark on this - he fell for the myth of City 'flair plus competence' and he WAS the CoE for heavens sake - but there is simply no way it wouldn't have panned out similar or worse under the Cons. But of course we can't prove this. So the claim persists. Grrr.
    Before Northern Rock, there was 150 years since the last British bank run. A period where the Conservative Party held office the majority of the time. But don’t let that get in the way of your nonsense.
    Suggest you get back to your specialist field of flying saucers.
    You’re a bit touchy.
    :smile: - You can't go saying I'm talking nonsense when you clearly haven't the first clue about it!

    Do I ever tell you you're talking nonsense on the saucers? No, I don't. I read and have a think.
    Perhaps one day I’ll meet you IRL and you can thereafter review my cv and decide if I am more or less qualified than you to talk about risk within the banking system.

    Also on UAPs, you are much like most people and have clearly still done no serious thinking or reading on the recent public discourse in the US. If you had, you would be thinking about it with a more open mind and frankly be amused that some people still think it a topic worthy of stigma or ridicule, bearing in mind the comments even in the last month by for example the serving Administrator of NASA or Michio Kaku, cofounder of string theory.

    It’s taken @kinabalu about 18 months to accept the premise that Lab Leak is plausible. He is a reasonably intelligent guy (but no genius), with a fantastically narrow and settled mind. You have to PRISE it open. I’d give up on UAPs if I were you
    The thing about UAPs is, so what? There is no doubt that there is weird and inexplicable shit going on, but what are we meant to do about it? Assume an Independence Day type alien megaship parks itself in geostationary orbit, and just sits there, what would we do about it? We'd wet our knickers about it and have experts giving it large on the telly about it for 6 months, but when there's no more to say, or do, about it, we'd just crack on with normal life. It's an axiom of advertising that you end up telling your target audience what to do next. UAP fanbois please note.
    Because the possible presence of non human intelligence in our skies and seas is absolutely fascinating. Surely?

    Almost as fascinating is the shrugging reaction from humans….
  • geoffwgeoffw Posts: 8,720
    ydoethur said:

    geoffw said:

    ydoethur said:

    geoffw said:

    ydoethur said:

    geoffw said:

    MaxPB said:

    moonshine said:

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    How cheap is to sequence a genome now? Did it hit $1000 yet? What’s the explanation for why most countries are not even bothering to try?
    See the reaction to SA being honest.
    There's a very good chance it didn't start there....
    The BBC is nowadays saying "first identified in SA"
    But it's travelled this whole world of ours from Barnsley to Peru...
    Possibly. But at least they are crediting SA with the identification and not implying that its origin is there.
    And another awesome cultural reference goes unremarked...
    Paddington Bear indeed, very awesome.

    The fact that I know Spitting Image songs and others don't is just ma maladie.
    Poor you. I hope you recover.

    MaxPB said:

    Eabhal said:

    What's the play if Omicron has no vaccine escape but is absolutely devastating to the unvaxxed?

    An exceptionally tough decision for the PM. An NHS overrun with anti-vaxxers hurts all of us, so do we put then at the back of the queue for treatment? Or do we have to accept a lockdown?

    We don't really have enough people in the non-immune categories for that to happen. The LSHTM model was quite prescient in that it predicted what hospitalisations would look like if everyone in the country was exposed to the virus tomorrow, it works out to about 40k people hospitalised here. It's not an earth shattering figure.
    Can you talk us through the numbers, or give a link? The Uk population is about 70 million, of whom 70% are fully vaccinated. Assume that nobody who is fully vaccinated catches a case of Covid serious enough to be hospitalised. That leaves 24 million people who are not fully vaccinated yet. You say that if they were all exposed to the virus tomorrow, less than 0.2% would be hospitalised? That would be excellent news, but it doesn't sound right.
    Well for a start how many of those 24 million are children who will not get adverse symptom? According to the ONS 20% of the population (which they have as 68 million) is under 16. That is around 13 million or so of the 22 million. So you are looking at around 11 million unvaccinated. And how many of those 11 million have had covid already? The numbers start to decline rapidly when you look at the reasonable exclusions.
    9m I think

  • MaxPBMaxPB Posts: 38,853

    MaxPB said:

    Eabhal said:

    What's the play if Omicron has no vaccine escape but is absolutely devastating to the unvaxxed?

    An exceptionally tough decision for the PM. An NHS overrun with anti-vaxxers hurts all of us, so do we put then at the back of the queue for treatment? Or do we have to accept a lockdown?

    We don't really have enough people in the non-immune categories for that to happen. The LSHTM model was quite prescient in that it predicted what hospitalisations would look like if everyone in the country was exposed to the virus tomorrow, it works out to about 40k people hospitalised here. It's not an earth shattering figure.
    Can you talk us through the numbers, or give a link? The Uk population is about 70 million, of whom 70% are fully vaccinated. Assume that nobody who is fully vaccinated catches a case of Covid serious enough to be hospitalised. That leaves 24 million people who are not fully vaccinated yet. You say that if they were all exposed to the virus tomorrow, less than 0.2% would be hospitalised? That would be excellent news, but it doesn't sound right.
    Sure, the number of people in the UK is ~67m of whom 46m 18+ are double vaxxed, in addition monitoring by Cambridge and Imperial shows that a further 13-17m kids and adults have immunity from prior infection. Then number of virus naive people in the UK is now thought to be between 5m and 8m people mostly in younger age categories.

    Additionally, hospitalisation is not uniform among age groups in the UK vaccine uptake among the key 60+ age group is close to 100% so the potential for hospitalisations is low in an age group that is most at risk of being hospitalised. PHE regularly produces an antibody monitoring study for UK adults and in those key age groups antibody presence from vaccines is almost always above 95% of those sampled and overall antibody presence is close to 100% when antibodies produced by natural infection are rolled in.

    Finally, the spread of virus naive people is primarily in the under 24 age category due to lower vaccination rates, the hospitalisation rate for these people is very low, as in if it's 1/10,000 being hospitalised that would be a surprise. For kids under 12 where there is no vaccination but high natural immunity there is almost zero hospitalisation, during the whole pandemic only a few hundred kids have needed hospital treatment and the survival rate is almost 100%.

    The Delta exit wave has essentially filled in the immunity gaps that the UK had after our reasonable but not outstanding vaccine campaign.

    Aiui the number will get smaller as more over 60s get their third doses.
  • LeonLeon Posts: 55,390
    MaxPB said:

    MaxPB said:

    Eabhal said:

    What's the play if Omicron has no vaccine escape but is absolutely devastating to the unvaxxed?

    An exceptionally tough decision for the PM. An NHS overrun with anti-vaxxers hurts all of us, so do we put then at the back of the queue for treatment? Or do we have to accept a lockdown?

    We don't really have enough people in the non-immune categories for that to happen. The LSHTM model was quite prescient in that it predicted what hospitalisations would look like if everyone in the country was exposed to the virus tomorrow, it works out to about 40k people hospitalised here. It's not an earth shattering figure.
    Can you talk us through the numbers, or give a link? The Uk population is about 70 million, of whom 70% are fully vaccinated. Assume that nobody who is fully vaccinated catches a case of Covid serious enough to be hospitalised. That leaves 24 million people who are not fully vaccinated yet. You say that if they were all exposed to the virus tomorrow, less than 0.2% would be hospitalised? That would be excellent news, but it doesn't sound right.
    Sure, the number of people in the UK is ~67m of whom 46m 18+ are double vaxxed, in addition monitoring by Cambridge and Imperial shows that a further 13-17m kids and adults have immunity from prior infection. Then number of virus naive people in the UK is now thought to be between 5m and 8m people mostly in younger age categories.

    Additionally, hospitalisation is not uniform among age groups in the UK vaccine uptake among the key 60+ age group is close to 100% so the potential for hospitalisations is low in an age group that is most at risk of being hospitalised. PHE regularly produces an antibody monitoring study for UK adults and in those key age groups antibody presence from vaccines is almost always above 95% of those sampled and overall antibody presence is close to 100% when antibodies produced by natural infection are rolled in.

    Finally, the spread of virus naive people is primarily in the under 24 age category due to lower vaccination rates, the hospitalisation rate for these people is very low, as in if it's 1/10,000 being hospitalised that would be a surprise. For kids under 12 where there is no vaccination but high natural immunity there is almost zero hospitalisation, during the whole pandemic only a few hundred kids have needed hospital treatment and the survival rate is almost 100%.

    The Delta exit wave has essentially filled in the immunity gaps that the UK had after our reasonable but not outstanding vaccine campaign.

    Aiui the number will get smaller as more over 60s get their third doses.
    Good summary.


    One note: there is that troubling and possibly anecdotal evidence from SA of “toddlers” going into hospital with suspected Omicron

    I have not seen it properly evidenced or verified, let alone scientifically investigated, but just a tiny reason for caution…
  • dixiedeandixiedean Posts: 29,409

    dixiedean said:

    Why is Dura refusing the Bill Gates sponsored microchipping?

    Tested on animals.
    Wasn't it reported the other day some youngish guy who was a vegan and objected for that very reason died after catching COVID.....his dying words, he wished he had got it.
    Yup.

    https://www.manchestereveningnews.co.uk/news/uk-news/vegan-who-refused-vaccine-because-22306094
    Know plenty vegans who've had it, mind
    I presume if you take this to the nth degree, I would have thought basically every modern medicine has been tested on animals at some point or involves compounds that have been, no?
    One would have thought so.
    How about buildings constructed using whipped horses? Or companies who made money from investors who were factory farmers?
    I've every admiration for vegans. It would be better for everyone if more were.
    But this smacks of fanaticism.
  • IshmaelZIshmaelZ Posts: 21,830
    Leon said:

    IshmaelZ said:

    Leon said:

    moonshine said:

    kinabalu said:

    moonshine said:

    kinabalu said:

    moonshine said:

    kinabalu said:

    kinabalu said:

    kinabalu said:

    MaxPB said:

    kinabalu said:

    TOPPING said:

    kinabalu said:

    For the zillionth time (does this really need repeating??) more regulation is not synonymous with better regulation. It's one of the most bizarre features of people on the Left that they seem to be totally incapable of getting their heads around this simplest of propositions. And I think it's a genuine intellectual failure in them, not just the obvious one of seeking to excuse a Labour Chancellor for the catastrophic dog's breakfast he made of financial regulation.

    Semi agreed. The regime put in place was rubbish and failed but there is no way on this earth that the old one, let alone any the Cons (who were fully signed up to 'light touch') would conceivably have implemented, could have headed off the crash of 08 or mitigated its impact on us to any significant degree.
    There is "the crash of 08" with its attendant CDS and so forth, and there is the first bank panic in the UK for XX years with people queuing round the block to get their money out. The former of course not; the latter, perhaps.
    The business model in question would need to have been prohibited in order to stop that. But the political culture of the time was 'these guys know what they're doing, leave them be, count the tax pounds'. Would this have been different with George Osborne or John McDonnell instead of Gordon Brown as Chancellor? (I now copy your last sentence).
    The Bank of England is still in charge of monitoring bank capital ratios and blocks RBS from buying ABN Amro. The Bank of England tells Northern Rock it's business model is built on sand and to hold 8% capital, not 0%. The Bank of England tells HBOS the same and to hold 8% reserve capital.

    That alone changes the nature and severity of the banking crisis in 08. You want to rewrite history and pretend it was investment banks that failed in the UK, it wasn't, it was standard old retail banks that shat the bed and needed bailing out.

    I still think we should have let all of them go bankrupt and stood behind the depositors. It was a mistake to for the state to step in and socialise losses.
    I'm not rewriting history. You're constructing an alternative history whereby under the 'light touch' laissez faire Tories, the City's reckless exuberance (being kind there) would have been tamed to such an extent that when global money markets had their near fatal seizure we here would have been largely protected. I find this fanciful in the extreme. Also the distinction between retail and investment banks' behaviour isn't a clear one. Eg, a large part of RBS's problem was paying a ludicrous amount for the poison pill that was ABN. It was full of junk. Barclays and the much vaunted Bob Diamond avoided that fate by the sheer dumb luck of being outbid by a bigger and more hubristic fool. Investment banks (and bankers) played a full part in the debacle on both sides of the Atlantic.
    Ask yourself this, why after such a long period of it not happening why did so many banks go bust after Gordon Brown changed the rules?

    Now I've spent the last decade working in banking and financial services regulation/compliance so I'm obviously an ingénue in these matters, so be gentle.
    Because the 08 crash and subsequent markets seizure exposed the fact that the City had long abdicated on risk management in a breathless chase for remuneration and status. Is my answer.

    Unless you're talking about a stream of failures before that?
    That Tory manifesto from 2005 again, in the wake of the pressure from Hannan and others' a year earlier to fully "Icelandise" the UK financial sector :

    "The best guarantee of future prosperity is a dynamic economy. New technology and the speed of global capital flows punish the inflexible and the sluggish. We need to reward risk-taking ...."
    Yep. There is mucho bollocks being talked in places. Brown deserves his big black mark on this - he fell for the myth of City 'flair plus competence' and he WAS the CoE for heavens sake - but there is simply no way it wouldn't have panned out similar or worse under the Cons. But of course we can't prove this. So the claim persists. Grrr.
    Before Northern Rock, there was 150 years since the last British bank run. A period where the Conservative Party held office the majority of the time. But don’t let that get in the way of your nonsense.
    Suggest you get back to your specialist field of flying saucers.
    You’re a bit touchy.
    :smile: - You can't go saying I'm talking nonsense when you clearly haven't the first clue about it!

    Do I ever tell you you're talking nonsense on the saucers? No, I don't. I read and have a think.
    Perhaps one day I’ll meet you IRL and you can thereafter review my cv and decide if I am more or less qualified than you to talk about risk within the banking system.

    Also on UAPs, you are much like most people and have clearly still done no serious thinking or reading on the recent public discourse in the US. If you had, you would be thinking about it with a more open mind and frankly be amused that some people still think it a topic worthy of stigma or ridicule, bearing in mind the comments even in the last month by for example the serving Administrator of NASA or Michio Kaku, cofounder of string theory.

    It’s taken @kinabalu about 18 months to accept the premise that Lab Leak is plausible. He is a reasonably intelligent guy (but no genius), with a fantastically narrow and settled mind. You have to PRISE it open. I’d give up on UAPs if I were you
    The thing about UAPs is, so what? There is no doubt that there is weird and inexplicable shit going on, but what are we meant to do about it? Assume an Independence Day type alien megaship parks itself in geostationary orbit, and just sits there, what would we do about it? We'd wet our knickers about it and have experts giving it large on the telly about it for 6 months, but when there's no more to say, or do, about it, we'd just crack on with normal life. It's an axiom of advertising that you end up telling your target audience what to do next. UAP fanbois please note.
    Because the possible presence of non human intelligence in our skies and seas is absolutely fascinating. Surely?

    Almost as fascinating is the shrugging reaction from humans….
    Absolutely, but when all we know is, There is some seriously strange shit going down, we run into the maxim: whereof we cannot speak, thereof we must be silent." The only recent development has been, an admission by the Pentagon that strange shit is going down. We knew that anyway.
  • They seem nice.


  • IshmaelZIshmaelZ Posts: 21,830
    ydoethur said:

    geoffw said:

    ydoethur said:

    geoffw said:

    ydoethur said:

    geoffw said:

    MaxPB said:

    moonshine said:

    rcs1000 said:

    SA is sequencing nearly as many cases as Germany & France (and 10% of the UK):



    https://twitter.com/ASPphysician/status/1465747726830915591?s=20

    I'm not going to lie, if you'd asked me where Cambodia would be on that chart, I wouldn't have said third.
    That's sequences per case

    The countries doing the heavy lifting globally:



    btw, kudos Ireland, who have uploaded the 3rd-most raw reads for their SARS-CoV-2 genomes. We're having a lot of discussion about potential artifacts, and it's great when one can easily figure out the answer to these questions by diving into the reads https://covid19dataportal.org/sequences?db=sra-experiment-covid19&size=15&crossReferencesOption=all#search-content

    https://twitter.com/theosanderson/status/1465113260475269120?s=20
    How cheap is to sequence a genome now? Did it hit $1000 yet? What’s the explanation for why most countries are not even bothering to try?
    See the reaction to SA being honest.
    There's a very good chance it didn't start there....
    The BBC is nowadays saying "first identified in SA"
    But it's travelled this whole world of ours from Barnsley to Peru...
    Possibly. But at least they are crediting SA with the identification and not implying that its origin is there.
    And another awesome cultural reference goes unremarked...
    Paddington Bear indeed, very awesome.

    The fact that I know Spitting Image songs and others don't is just ma maladie.
    You seem to have a seville case of it.
  • dixiedeandixiedean Posts: 29,409
    Was just about to post that Newcastle are winning.
    But I missed that tiny window of opportunity.
    It may never happen again.
  • sladeslade Posts: 2,041
    Just watched the most dominant victory in football ever. Possession 86-14, Shots 64-0, Shots on target 31-0, corners 15-0. The result; England Ladies 20, Latvia Ladies 0. Four hat tricks and one player scored 4 having never scored before.
  • MaxPBMaxPB Posts: 38,853
    Leon said:

    MaxPB said:

    MaxPB said:

    Eabhal said:

    What's the play if Omicron has no vaccine escape but is absolutely devastating to the unvaxxed?

    An exceptionally tough decision for the PM. An NHS overrun with anti-vaxxers hurts all of us, so do we put then at the back of the queue for treatment? Or do we have to accept a lockdown?

    We don't really have enough people in the non-immune categories for that to happen. The LSHTM model was quite prescient in that it predicted what hospitalisations would look like if everyone in the country was exposed to the virus tomorrow, it works out to about 40k people hospitalised here. It's not an earth shattering figure.
    Can you talk us through the numbers, or give a link? The Uk population is about 70 million, of whom 70% are fully vaccinated. Assume that nobody who is fully vaccinated catches a case of Covid serious enough to be hospitalised. That leaves 24 million people who are not fully vaccinated yet. You say that if they were all exposed to the virus tomorrow, less than 0.2% would be hospitalised? That would be excellent news, but it doesn't sound right.
    Sure, the number of people in the UK is ~67m of whom 46m 18+ are double vaxxed, in addition monitoring by Cambridge and Imperial shows that a further 13-17m kids and adults have immunity from prior infection. Then number of virus naive people in the UK is now thought to be between 5m and 8m people mostly in younger age categories.

    Additionally, hospitalisation is not uniform among age groups in the UK vaccine uptake among the key 60+ age group is close to 100% so the potential for hospitalisations is low in an age group that is most at risk of being hospitalised. PHE regularly produces an antibody monitoring study for UK adults and in those key age groups antibody presence from vaccines is almost always above 95% of those sampled and overall antibody presence is close to 100% when antibodies produced by natural infection are rolled in.

    Finally, the spread of virus naive people is primarily in the under 24 age category due to lower vaccination rates, the hospitalisation rate for these people is very low, as in if it's 1/10,000 being hospitalised that would be a surprise. For kids under 12 where there is no vaccination but high natural immunity there is almost zero hospitalisation, during the whole pandemic only a few hundred kids have needed hospital treatment and the survival rate is almost 100%.

    The Delta exit wave has essentially filled in the immunity gaps that the UK had after our reasonable but not outstanding vaccine campaign.

    Aiui the number will get smaller as more over 60s get their third doses.
    Good summary.


    One note: there is that troubling and possibly anecdotal evidence from SA of “toddlers” going into hospital with suspected Omicron

    I have not seen it properly evidenced or verified, let alone scientifically investigated, but just a tiny reason for caution…
    We have this with every variant, I remember the blue tick wankers saying that Boris was killing kids by getting rid of the bubbles for the school year this September because Delta was magically completely different from Alpha. Even last year with Alpha we had reports of kids being hospitalised at a higher rate but then it just turned out that no, hospitals had just started testing everyone so registered positive tests among kids that came in for other issues. We also had that Kawasaki disease scare right at the beginning which was, again, egged on by the same blue tick wankers looking to cause panic for likes.

    I'm not ruling out the possibility, though my reasoning for being sceptical is sound. The doctor on Sunday explained that it was all to do with ACE-2 receptors, old people have loads, under 40s have not many and kids have barely any. It's extremely difficult for the virus to actually enter cells in key parts of the body for kids which is why they don't present severe symptoms.
  • ThomasNasheThomasNashe Posts: 5,331
    dixiedean said:

    Was just about to post that Newcastle are winning.
    But I missed that tiny window of opportunity.
    It may never happen again.

    Gonna be the wealthiest team in the Championship.
  • MaxPB said:

    Leon said:

    MaxPB said:

    MaxPB said:

    Eabhal said:

    What's the play if Omicron has no vaccine escape but is absolutely devastating to the unvaxxed?

    An exceptionally tough decision for the PM. An NHS overrun with anti-vaxxers hurts all of us, so do we put then at the back of the queue for treatment? Or do we have to accept a lockdown?

    We don't really have enough people in the non-immune categories for that to happen. The LSHTM model was quite prescient in that it predicted what hospitalisations would look like if everyone in the country was exposed to the virus tomorrow, it works out to about 40k people hospitalised here. It's not an earth shattering figure.
    Can you talk us through the numbers, or give a link? The Uk population is about 70 million, of whom 70% are fully vaccinated. Assume that nobody who is fully vaccinated catches a case of Covid serious enough to be hospitalised. That leaves 24 million people who are not fully vaccinated yet. You say that if they were all exposed to the virus tomorrow, less than 0.2% would be hospitalised? That would be excellent news, but it doesn't sound right.
    Sure, the number of people in the UK is ~67m of whom 46m 18+ are double vaxxed, in addition monitoring by Cambridge and Imperial shows that a further 13-17m kids and adults have immunity from prior infection. Then number of virus naive people in the UK is now thought to be between 5m and 8m people mostly in younger age categories.

    Additionally, hospitalisation is not uniform among age groups in the UK vaccine uptake among the key 60+ age group is close to 100% so the potential for hospitalisations is low in an age group that is most at risk of being hospitalised. PHE regularly produces an antibody monitoring study for UK adults and in those key age groups antibody presence from vaccines is almost always above 95% of those sampled and overall antibody presence is close to 100% when antibodies produced by natural infection are rolled in.

    Finally, the spread of virus naive people is primarily in the under 24 age category due to lower vaccination rates, the hospitalisation rate for these people is very low, as in if it's 1/10,000 being hospitalised that would be a surprise. For kids under 12 where there is no vaccination but high natural immunity there is almost zero hospitalisation, during the whole pandemic only a few hundred kids have needed hospital treatment and the survival rate is almost 100%.

    The Delta exit wave has essentially filled in the immunity gaps that the UK had after our reasonable but not outstanding vaccine campaign.

    Aiui the number will get smaller as more over 60s get their third doses.
    Good summary.


    One note: there is that troubling and possibly anecdotal evidence from SA of “toddlers” going into hospital with suspected Omicron

    I have not seen it properly evidenced or verified, let alone scientifically investigated, but just a tiny reason for caution…
    We have this with every variant, I remember the blue tick wankers saying that Boris was killing kids by getting rid of the bubbles for the school year this September because Delta was magically completely different from Alpha. Even last year with Alpha we had reports of kids being hospitalised at a higher rate but then it just turned out that no, hospitals had just started testing everyone so registered positive tests among kids that came in for other issues. We also had that Kawasaki disease scare right at the beginning which was, again, egged on by the same blue tick wankers looking to cause panic for likes.

    I'm not ruling out the possibility, though my reasoning for being sceptical is sound. The doctor on Sunday explained that it was all to do with ACE-2 receptors, old people have loads, under 40s have not many and kids have barely any. It's extremely difficult for the virus to actually enter cells in key parts of the body for kids which is why they don't present severe symptoms.
    Don't forget the 99% of survivors also get long covid...
  • Some supermarkets have said they will not be enforcing new face mask rules brought back in after concerns about the Omicron coronavirus variant.

    Supermarket chain Iceland told the BBC its staff would not ask customers to wear masks to stop them facing abuse.

    Tesco, the largest UK supermarket chain, will just be putting signs up to remind customers about face mask rules, the BBC understands.

    Aldi and Lidl are also understood to have no plans to challenge customers.

    https://www.bbc.com/news/business-59481287
  • I don't really follow Mike's logic as Cooper got fewer votes than Burnham in 2015 albeit not by much (17% to 19%).

    I'm also not sure standing down from the Home Affairs sekect committee was very sensible.
  • glwglw Posts: 9,906
    TimS said:

    Maybe my maths is wrong here but:

    They say breakthrough infections in those previously infected are twice the rate as for Delta (bad)

    But for the fully vaccinated the efficacy goes down just from 95 to 90% (good).

    But isn’t that vaccine data equivalent to a doubling of breakthrough risk (10% vs 5%)?

    Still pretty decent data to be honest, because both numbers suggest immune escape isn’t that great.

    Yes whilst still being good a drop from 95% to 90% means that the risk has doubled. My immediate view is that it's not as bad as feared, but still bad enough to potentially cause some big problems in a population where vaccination is limited or waning. For the UK we really need to get cracking with the boosters, and look at what can be done to get the unvaccinated to change their minds.
  • IshmaelZIshmaelZ Posts: 21,830
    dixiedean said:

    dixiedean said:

    Why is Dura refusing the Bill Gates sponsored microchipping?

    Tested on animals.
    Wasn't it reported the other day some youngish guy who was a vegan and objected for that very reason died after catching COVID.....his dying words, he wished he had got it.
    Yup.

    https://www.manchestereveningnews.co.uk/news/uk-news/vegan-who-refused-vaccine-because-22306094
    Know plenty vegans who've had it, mind
    I presume if you take this to the nth degree, I would have thought basically every modern medicine has been tested on animals at some point or involves compounds that have been, no?
    One would have thought so.
    How about buildings constructed using whipped horses? Or companies who made money from investors who were factory farmers?
    I've every admiration for vegans. It would be better for everyone if more were.
    But this smacks of fanaticism.
    What gets me is the petrol thing: the stuff is made of the corpses of teeny weeny animals, and saying that it was all a long time ago is frankly pure timeism/speciesism

    The only true guide is Jim Morrison: I just wanna have my kicks before the whole shithouse goes up in flames.
  • dixiedean said:

    Was just about to post that Newcastle are winning.
    But I missed that tiny window of opportunity.
    It may never happen again.

    Gonna be the wealthiest team in the Championship.
    Mbappe is going to score 562 goals in next year's Championship.
  • IshmaelZIshmaelZ Posts: 21,830

    Some supermarkets have said they will not be enforcing new face mask rules brought back in after concerns about the Omicron coronavirus variant.

    Supermarket chain Iceland told the BBC its staff would not ask customers to wear masks to stop them facing abuse.

    Tesco, the largest UK supermarket chain, will just be putting signs up to remind customers about face mask rules, the BBC understands.

    Aldi and Lidl are also understood to have no plans to challenge customers.

    https://www.bbc.com/news/business-59481287

    Aldi and Lidl do not have customer-challenging staff to spare, uncoincidentally
  • LeonLeon Posts: 55,390
    MaxPB said:

    Leon said:

    MaxPB said:

    MaxPB said:

    Eabhal said:

    What's the play if Omicron has no vaccine escape but is absolutely devastating to the unvaxxed?

    An exceptionally tough decision for the PM. An NHS overrun with anti-vaxxers hurts all of us, so do we put then at the back of the queue for treatment? Or do we have to accept a lockdown?

    We don't really have enough people in the non-immune categories for that to happen. The LSHTM model was quite prescient in that it predicted what hospitalisations would look like if everyone in the country was exposed to the virus tomorrow, it works out to about 40k people hospitalised here. It's not an earth shattering figure.
    Can you talk us through the numbers, or give a link? The Uk population is about 70 million, of whom 70% are fully vaccinated. Assume that nobody who is fully vaccinated catches a case of Covid serious enough to be hospitalised. That leaves 24 million people who are not fully vaccinated yet. You say that if they were all exposed to the virus tomorrow, less than 0.2% would be hospitalised? That would be excellent news, but it doesn't sound right.
    Sure, the number of people in the UK is ~67m of whom 46m 18+ are double vaxxed, in addition monitoring by Cambridge and Imperial shows that a further 13-17m kids and adults have immunity from prior infection. Then number of virus naive people in the UK is now thought to be between 5m and 8m people mostly in younger age categories.

    Additionally, hospitalisation is not uniform among age groups in the UK vaccine uptake among the key 60+ age group is close to 100% so the potential for hospitalisations is low in an age group that is most at risk of being hospitalised. PHE regularly produces an antibody monitoring study for UK adults and in those key age groups antibody presence from vaccines is almost always above 95% of those sampled and overall antibody presence is close to 100% when antibodies produced by natural infection are rolled in.

    Finally, the spread of virus naive people is primarily in the under 24 age category due to lower vaccination rates, the hospitalisation rate for these people is very low, as in if it's 1/10,000 being hospitalised that would be a surprise. For kids under 12 where there is no vaccination but high natural immunity there is almost zero hospitalisation, during the whole pandemic only a few hundred kids have needed hospital treatment and the survival rate is almost 100%.

    The Delta exit wave has essentially filled in the immunity gaps that the UK had after our reasonable but not outstanding vaccine campaign.

    Aiui the number will get smaller as more over 60s get their third doses.
    Good summary.


    One note: there is that troubling and possibly anecdotal evidence from SA of “toddlers” going into hospital with suspected Omicron

    I have not seen it properly evidenced or verified, let alone scientifically investigated, but just a tiny reason for caution…
    We have this with every variant, I remember the blue tick wankers saying that Boris was killing kids by getting rid of the bubbles for the school year this September because Delta was magically completely different from Alpha. Even last year with Alpha we had reports of kids being hospitalised at a higher rate but then it just turned out that no, hospitals had just started testing everyone so registered positive tests among kids that came in for other issues. We also had that Kawasaki disease scare right at the beginning which was, again, egged on by the same blue tick wankers looking to cause panic for likes.

    I'm not ruling out the possibility, though my reasoning for being sceptical is sound. The doctor on Sunday explained that it was all to do with ACE-2 receptors, old people have loads, under 40s have not many and kids have barely any. It's extremely difficult for the virus to actually enter cells in key parts of the body for kids which is why they don't present severe symptoms.
    It would certainly be a bizarre evolution if it suddenly attacked tiny kids
  • MaxPBMaxPB Posts: 38,853
    glw said:

    TimS said:

    Maybe my maths is wrong here but:

    They say breakthrough infections in those previously infected are twice the rate as for Delta (bad)

    But for the fully vaccinated the efficacy goes down just from 95 to 90% (good).

    But isn’t that vaccine data equivalent to a doubling of breakthrough risk (10% vs 5%)?

    Still pretty decent data to be honest, because both numbers suggest immune escape isn’t that great.

    Yes whilst still being good a drop from 95% to 90% means that the risk has doubled. My immediate view is that it's not as bad as feared, but still bad enough to potentially cause some big problems in a population where vaccination is limited or waning. For the UK we really need to get cracking with the boosters, and look at what can be done to get the unvaccinated to change their minds.
    It really depends on whether naturally acquired immunity still prevents severe symptoms almost entirely. It's not such a big deal for people to get reinfected if they just get a few sniffles. The danger to the unvaccinated will a weary population who don't want to do 10 days isolation for that reason and simply won't get tested for a few sniffles.
  • isamisam Posts: 41,118
    Farooq said:

    They seem nice.


    Which five PBers do you think are likeliest to be up on that bridge?
    tim, RoyGBiv, Hugh, Mick Pork and James Kelly
  • moonshinemoonshine Posts: 5,748
    IshmaelZ said:

    Leon said:

    moonshine said:

    kinabalu said:

    moonshine said:

    kinabalu said:

    moonshine said:

    kinabalu said:

    kinabalu said:

    kinabalu said:

    MaxPB said:

    kinabalu said:

    TOPPING said:

    kinabalu said:

    For the zillionth time (does this really need repeating??) more regulation is not synonymous with better regulation. It's one of the most bizarre features of people on the Left that they seem to be totally incapable of getting their heads around this simplest of propositions. And I think it's a genuine intellectual failure in them, not just the obvious one of seeking to excuse a Labour Chancellor for the catastrophic dog's breakfast he made of financial regulation.

    Semi agreed. The regime put in place was rubbish and failed but there is no way on this earth that the old one, let alone any the Cons (who were fully signed up to 'light touch') would conceivably have implemented, could have headed off the crash of 08 or mitigated its impact on us to any significant degree.
    There is "the crash of 08" with its attendant CDS and so forth, and there is the first bank panic in the UK for XX years with people queuing round the block to get their money out. The former of course not; the latter, perhaps.
    The business model in question would need to have been prohibited in order to stop that. But the political culture of the time was 'these guys know what they're doing, leave them be, count the tax pounds'. Would this have been different with George Osborne or John McDonnell instead of Gordon Brown as Chancellor? (I now copy your last sentence).
    The Bank of England is still in charge of monitoring bank capital ratios and blocks RBS from buying ABN Amro. The Bank of England tells Northern Rock it's business model is built on sand and to hold 8% capital, not 0%. The Bank of England tells HBOS the same and to hold 8% reserve capital.

    That alone changes the nature and severity of the banking crisis in 08. You want to rewrite history and pretend it was investment banks that failed in the UK, it wasn't, it was standard old retail banks that shat the bed and needed bailing out.

    I still think we should have let all of them go bankrupt and stood behind the depositors. It was a mistake to for the state to step in and socialise losses.
    I'm not rewriting history. You're constructing an alternative history whereby under the 'light touch' laissez faire Tories, the City's reckless exuberance (being kind there) would have been tamed to such an extent that when global money markets had their near fatal seizure we here would have been largely protected. I find this fanciful in the extreme. Also the distinction between retail and investment banks' behaviour isn't a clear one. Eg, a large part of RBS's problem was paying a ludicrous amount for the poison pill that was ABN. It was full of junk. Barclays and the much vaunted Bob Diamond avoided that fate by the sheer dumb luck of being outbid by a bigger and more hubristic fool. Investment banks (and bankers) played a full part in the debacle on both sides of the Atlantic.
    Ask yourself this, why after such a long period of it not happening why did so many banks go bust after Gordon Brown changed the rules?

    Now I've spent the last decade working in banking and financial services regulation/compliance so I'm obviously an ingénue in these matters, so be gentle.
    Because the 08 crash and subsequent markets seizure exposed the fact that the City had long abdicated on risk management in a breathless chase for remuneration and status. Is my answer.

    Unless you're talking about a stream of failures before that?
    That Tory manifesto from 2005 again, in the wake of the pressure from Hannan and others' a year earlier to fully "Icelandise" the UK financial sector :

    "The best guarantee of future prosperity is a dynamic economy. New technology and the speed of global capital flows punish the inflexible and the sluggish. We need to reward risk-taking ...."
    Yep. There is mucho bollocks being talked in places. Brown deserves his big black mark on this - he fell for the myth of City 'flair plus competence' and he WAS the CoE for heavens sake - but there is simply no way it wouldn't have panned out similar or worse under the Cons. But of course we can't prove this. So the claim persists. Grrr.
    Before Northern Rock, there was 150 years since the last British bank run. A period where the Conservative Party held office the majority of the time. But don’t let that get in the way of your nonsense.
    Suggest you get back to your specialist field of flying saucers.
    You’re a bit touchy.
    :smile: - You can't go saying I'm talking nonsense when you clearly haven't the first clue about it!

    Do I ever tell you you're talking nonsense on the saucers? No, I don't. I read and have a think.
    Perhaps one day I’ll meet you IRL and you can thereafter review my cv and decide if I am more or less qualified than you to talk about risk within the banking system.

    Also on UAPs, you are much like most people and have clearly still done no serious thinking or reading on the recent public discourse in the US. If you had, you would be thinking about it with a more open mind and frankly be amused that some people still think it a topic worthy of stigma or ridicule, bearing in mind the comments even in the last month by for example the serving Administrator of NASA or Michio Kaku, cofounder of string theory.

    It’s taken @kinabalu about 18 months to accept the premise that Lab Leak is plausible. He is a reasonably intelligent guy (but no genius), with a fantastically narrow and settled mind. You have to PRISE it open. I’d give up on UAPs if I were you
    The thing about UAPs is, so what? There is no doubt that there is weird and inexplicable shit going on, but what are we meant to do about it? Assume an Independence Day type alien megaship parks itself in geostationary orbit, and just sits there, what would we do about it? We'd wet our knickers about it and have experts giving it large on the telly about it for 6 months, but when there's no more to say, or do, about it, we'd just crack on with normal life. It's an axiom of advertising that you end up telling your target audience what to do next. UAP fanbois please note.
    Step 1 is to gain insight, of which right now we have very little. Rationalise as best we can any threat level, which is radically different depending upon whether UAP are human origin or “other”. Threat being capability x intent. There’s been a long period already to make this assessment. So let’s hear it please.

    Step 2 is to pass the subject out the hands of the security apparatus and into civilian science. As the US government report describes its “catch all other bin” of categorisation, “pending scientific advances that allowed us to better understand them”. Hence the ground breaking comments by sections of civilian science already emerging in the months since that statement. But we haven’t yet had the transfer moment from Step 1 to Step 2, more is the pity, the data are kept under a cloud of national security and still only being drip fed.

    Step 3, In time, we may then learn how to unleash beneficial technology that would transform global society. Some apes have been observed to spear fish, a skill acquired through observing humans. Despite humans never having tried to teach them that or anything else, nor interfering with their social hierarchies, and being widely apathetic rather than antagonist to their fate.

    Still, we are thinking beings. So perhaps there is a Step 4 that allows us to learn our place in the cosmos, our history and our future. Which I guess would entail some kind of direct interaction with the Pentagon’s “catch all other bin”.

    Unsettling for most people to think about that of course, it’s easier to outsource those questions to scripture writers and focus on day to day life. And probably leads to a happier life all said and done. And if that’s your bag then fine, ignore the dreadnought floating in geostationary orbit. That is what most people are doing.
  • IshmaelZIshmaelZ Posts: 21,830

    MaxPB said:

    Leon said:

    MaxPB said:

    MaxPB said:

    Eabhal said:

    What's the play if Omicron has no vaccine escape but is absolutely devastating to the unvaxxed?

    An exceptionally tough decision for the PM. An NHS overrun with anti-vaxxers hurts all of us, so do we put then at the back of the queue for treatment? Or do we have to accept a lockdown?

    We don't really have enough people in the non-immune categories for that to happen. The LSHTM model was quite prescient in that it predicted what hospitalisations would look like if everyone in the country was exposed to the virus tomorrow, it works out to about 40k people hospitalised here. It's not an earth shattering figure.
    Can you talk us through the numbers, or give a link? The Uk population is about 70 million, of whom 70% are fully vaccinated. Assume that nobody who is fully vaccinated catches a case of Covid serious enough to be hospitalised. That leaves 24 million people who are not fully vaccinated yet. You say that if they were all exposed to the virus tomorrow, less than 0.2% would be hospitalised? That would be excellent news, but it doesn't sound right.
    Sure, the number of people in the UK is ~67m of whom 46m 18+ are double vaxxed, in addition monitoring by Cambridge and Imperial shows that a further 13-17m kids and adults have immunity from prior infection. Then number of virus naive people in the UK is now thought to be between 5m and 8m people mostly in younger age categories.

    Additionally, hospitalisation is not uniform among age groups in the UK vaccine uptake among the key 60+ age group is close to 100% so the potential for hospitalisations is low in an age group that is most at risk of being hospitalised. PHE regularly produces an antibody monitoring study for UK adults and in those key age groups antibody presence from vaccines is almost always above 95% of those sampled and overall antibody presence is close to 100% when antibodies produced by natural infection are rolled in.

    Finally, the spread of virus naive people is primarily in the under 24 age category due to lower vaccination rates, the hospitalisation rate for these people is very low, as in if it's 1/10,000 being hospitalised that would be a surprise. For kids under 12 where there is no vaccination but high natural immunity there is almost zero hospitalisation, during the whole pandemic only a few hundred kids have needed hospital treatment and the survival rate is almost 100%.

    The Delta exit wave has essentially filled in the immunity gaps that the UK had after our reasonable but not outstanding vaccine campaign.

    Aiui the number will get smaller as more over 60s get their third doses.
    Good summary.


    One note: there is that troubling and possibly anecdotal evidence from SA of “toddlers” going into hospital with suspected Omicron

    I have not seen it properly evidenced or verified, let alone scientifically investigated, but just a tiny reason for caution…
    We have this with every variant, I remember the blue tick wankers saying that Boris was killing kids by getting rid of the bubbles for the school year this September because Delta was magically completely different from Alpha. Even last year with Alpha we had reports of kids being hospitalised at a higher rate but then it just turned out that no, hospitals had just started testing everyone so registered positive tests among kids that came in for other issues. We also had that Kawasaki disease scare right at the beginning which was, again, egged on by the same blue tick wankers looking to cause panic for likes.

    I'm not ruling out the possibility, though my reasoning for being sceptical is sound. The doctor on Sunday explained that it was all to do with ACE-2 receptors, old people have loads, under 40s have not many and kids have barely any. It's extremely difficult for the virus to actually enter cells in key parts of the body for kids which is why they don't present severe symptoms.
    Don't forget the 99% of survivors also get long covid...
    Try to master the basics of detection bias before embarking on a comedy career...
  • LeonLeon Posts: 55,390
    glw said:

    TimS said:

    Maybe my maths is wrong here but:

    They say breakthrough infections in those previously infected are twice the rate as for Delta (bad)

    But for the fully vaccinated the efficacy goes down just from 95 to 90% (good).

    But isn’t that vaccine data equivalent to a doubling of breakthrough risk (10% vs 5%)?

    Still pretty decent data to be honest, because both numbers suggest immune escape isn’t that great.

    Yes whilst still being good a drop from 95% to 90% means that the risk has doubled. My immediate view is that it's not as bad as feared, but still bad enough to potentially cause some big problems in a population where vaccination is limited or waning. For the UK we really need to get cracking with the boosters, and look at what can be done to get the unvaccinated to change their minds.
    If this SA/Israeli data verifies, the pressure on the unvaxxed will be intense. Likewise the pressure on governments to badger the unvaxxed into submission

    Why should the rest of us tolerate lockdown and horror to save their sorry asses?
  • IshmaelZ said:

    MaxPB said:

    Leon said:

    MaxPB said:

    MaxPB said:

    Eabhal said:

    What's the play if Omicron has no vaccine escape but is absolutely devastating to the unvaxxed?

    An exceptionally tough decision for the PM. An NHS overrun with anti-vaxxers hurts all of us, so do we put then at the back of the queue for treatment? Or do we have to accept a lockdown?

    We don't really have enough people in the non-immune categories for that to happen. The LSHTM model was quite prescient in that it predicted what hospitalisations would look like if everyone in the country was exposed to the virus tomorrow, it works out to about 40k people hospitalised here. It's not an earth shattering figure.
    Can you talk us through the numbers, or give a link? The Uk population is about 70 million, of whom 70% are fully vaccinated. Assume that nobody who is fully vaccinated catches a case of Covid serious enough to be hospitalised. That leaves 24 million people who are not fully vaccinated yet. You say that if they were all exposed to the virus tomorrow, less than 0.2% would be hospitalised? That would be excellent news, but it doesn't sound right.
    Sure, the number of people in the UK is ~67m of whom 46m 18+ are double vaxxed, in addition monitoring by Cambridge and Imperial shows that a further 13-17m kids and adults have immunity from prior infection. Then number of virus naive people in the UK is now thought to be between 5m and 8m people mostly in younger age categories.

    Additionally, hospitalisation is not uniform among age groups in the UK vaccine uptake among the key 60+ age group is close to 100% so the potential for hospitalisations is low in an age group that is most at risk of being hospitalised. PHE regularly produces an antibody monitoring study for UK adults and in those key age groups antibody presence from vaccines is almost always above 95% of those sampled and overall antibody presence is close to 100% when antibodies produced by natural infection are rolled in.

    Finally, the spread of virus naive people is primarily in the under 24 age category due to lower vaccination rates, the hospitalisation rate for these people is very low, as in if it's 1/10,000 being hospitalised that would be a surprise. For kids under 12 where there is no vaccination but high natural immunity there is almost zero hospitalisation, during the whole pandemic only a few hundred kids have needed hospital treatment and the survival rate is almost 100%.

    The Delta exit wave has essentially filled in the immunity gaps that the UK had after our reasonable but not outstanding vaccine campaign.

    Aiui the number will get smaller as more over 60s get their third doses.
    Good summary.


    One note: there is that troubling and possibly anecdotal evidence from SA of “toddlers” going into hospital with suspected Omicron

    I have not seen it properly evidenced or verified, let alone scientifically investigated, but just a tiny reason for caution…
    We have this with every variant, I remember the blue tick wankers saying that Boris was killing kids by getting rid of the bubbles for the school year this September because Delta was magically completely different from Alpha. Even last year with Alpha we had reports of kids being hospitalised at a higher rate but then it just turned out that no, hospitals had just started testing everyone so registered positive tests among kids that came in for other issues. We also had that Kawasaki disease scare right at the beginning which was, again, egged on by the same blue tick wankers looking to cause panic for likes.

    I'm not ruling out the possibility, though my reasoning for being sceptical is sound. The doctor on Sunday explained that it was all to do with ACE-2 receptors, old people have loads, under 40s have not many and kids have barely any. It's extremely difficult for the virus to actually enter cells in key parts of the body for kids which is why they don't present severe symptoms.
    Don't forget the 99% of survivors also get long covid...
    Try to master the basics of detection bias before embarking on a comedy career...
    Did I accidentally run over your toes with my shopping trolley or something? You seem very agitated at my every post.
  • MaxPBMaxPB Posts: 38,853
    Leon said:

    glw said:

    TimS said:

    Maybe my maths is wrong here but:

    They say breakthrough infections in those previously infected are twice the rate as for Delta (bad)

    But for the fully vaccinated the efficacy goes down just from 95 to 90% (good).

    But isn’t that vaccine data equivalent to a doubling of breakthrough risk (10% vs 5%)?

    Still pretty decent data to be honest, because both numbers suggest immune escape isn’t that great.

    Yes whilst still being good a drop from 95% to 90% means that the risk has doubled. My immediate view is that it's not as bad as feared, but still bad enough to potentially cause some big problems in a population where vaccination is limited or waning. For the UK we really need to get cracking with the boosters, and look at what can be done to get the unvaccinated to change their minds.
    If this SA/Israeli data verifies, the pressure on the unvaxxed will be intense. Likewise the pressure on governments to badger the unvaxxed into submission

    Why should the rest of us tolerate lockdown and horror to save their sorry asses?
    I don't think we'd lock down anyway. In the model the majority of our hospitalisations were in breakthrough categories, very few in the unvaccinated because of age profile. When they next update it they will be able to plug in three dose efficacy with the latest coverage of almost 20m third doses done.
  • Over lockdown, I formed a relationship with a pen pal in prison. getting to know her, she told me of the pain and hardship in her life, trying to start life anew, only to fall in love with a bad man. Today, her trial in New York begins. She'd appreciate all thoughts and prayers.

    https://twitter.com/HKesvani/status/1465792574145249285
  • Farooq said:

    They seem nice.


    Which five PBers do you think are likeliest to be up on that bridge?
    The spelling seems all in order so that narrows it down a bit.
  • dixiedeandixiedean Posts: 29,409
    Leon said:

    glw said:

    TimS said:

    Maybe my maths is wrong here but:

    They say breakthrough infections in those previously infected are twice the rate as for Delta (bad)

    But for the fully vaccinated the efficacy goes down just from 95 to 90% (good).

    But isn’t that vaccine data equivalent to a doubling of breakthrough risk (10% vs 5%)?

    Still pretty decent data to be honest, because both numbers suggest immune escape isn’t that great.

    Yes whilst still being good a drop from 95% to 90% means that the risk has doubled. My immediate view is that it's not as bad as feared, but still bad enough to potentially cause some big problems in a population where vaccination is limited or waning. For the UK we really need to get cracking with the boosters, and look at what can be done to get the unvaccinated to change their minds.
    If this SA/Israeli data verifies, the pressure on the unvaxxed will be intense. Likewise the pressure on governments to badger the unvaxxed into submission

    Why should the rest of us tolerate lockdown and horror to save their sorry asses?
    The PM was asked about the 5 m totally unvaxxed (journalist's figure) today.
    Answer came there none. If they start filling the hospitals again this will become untenable.
  • IshmaelZIshmaelZ Posts: 21,830
    moonshine said:

    IshmaelZ said:

    Leon said:

    moonshine said:

    kinabalu said:

    moonshine said:

    kinabalu said:

    moonshine said:

    kinabalu said:

    kinabalu said:

    kinabalu said:

    MaxPB said:

    kinabalu said:

    TOPPING said:

    kinabalu said:

    For the zillionth time (does this really need repeating??) more regulation is not synonymous with better regulation. It's one of the most bizarre features of people on the Left that they seem to be totally incapable of getting their heads around this simplest of propositions. And I think it's a genuine intellectual failure in them, not just the obvious one of seeking to excuse a Labour Chancellor for the catastrophic dog's breakfast he made of financial regulation.

    Semi agreed. The regime put in place was rubbish and failed but there is no way on this earth that the old one, let alone any the Cons (who were fully signed up to 'light touch') would conceivably have implemented, could have headed off the crash of 08 or mitigated its impact on us to any significant degree.
    There is "the crash of 08" with its attendant CDS and so forth, and there is the first bank panic in the UK for XX years with people queuing round the block to get their money out. The former of course not; the latter, perhaps.
    The business model in question would need to have been prohibited in order to stop that. But the political culture of the time was 'these guys know what they're doing, leave them be, count the tax pounds'. Would this have been different with George Osborne or John McDonnell instead of Gordon Brown as Chancellor? (I now copy your last sentence).
    The Bank of England is still in charge of monitoring bank capital ratios and blocks RBS from buying ABN Amro. The Bank of England tells Northern Rock it's business model is built on sand and to hold 8% capital, not 0%. The Bank of England tells HBOS the same and to hold 8% reserve capital.

    That alone changes the nature and severity of the banking crisis in 08. You want to rewrite history and pretend it was investment banks that failed in the UK, it wasn't, it was standard old retail banks that shat the bed and needed bailing out.

    I still think we should have let all of them go bankrupt and stood behind the depositors. It was a mistake to for the state to step in and socialise losses.
    I'm not rewriting history. You're constructing an alternative history whereby under the 'light touch' laissez faire Tories, the City's reckless exuberance (being kind there) would have been tamed to such an extent that when global money markets had their near fatal seizure we here would have been largely protected. I find this fanciful in the extreme. Also the distinction between retail and investment banks' behaviour isn't a clear one. Eg, a large part of RBS's problem was paying a ludicrous amount for the poison pill that was ABN. It was full of junk. Barclays and the much vaunted Bob Diamond avoided that fate by the sheer dumb luck of being outbid by a bigger and more hubristic fool. Investment banks (and bankers) played a full part in the debacle on both sides of the Atlantic.
    Ask yourself this, why after such a long period of it not happening why did so many banks go bust after Gordon Brown changed the rules?

    Now I've spent the last decade working in banking and financial services regulation/compliance so I'm obviously an ingénue in these matters, so be gentle.
    Because the 08 crash and subsequent markets seizure exposed the fact that the City had long abdicated on risk management in a breathless chase for remuneration and status. Is my answer.

    Unless you're talking about a stream of failures before that?
    That Tory manifesto from 2005 again, in the wake of the pressure from Hannan and others' a year earlier to fully "Icelandise" the UK financial sector :

    "The best guarantee of future prosperity is a dynamic economy. New technology and the speed of global capital flows punish the inflexible and the sluggish. We need to reward risk-taking ...."
    Yep. There is mucho bollocks being talked in places. Brown deserves his big black mark on this - he fell for the myth of City 'flair plus competence' and he WAS the CoE for heavens sake - but there is simply no way it wouldn't have panned out similar or worse under the Cons. But of course we can't prove this. So the claim persists. Grrr.
    Before Northern Rock, there was 150 years since the last British bank run. A period where the Conservative Party held office the majority of the time. But don’t let that get in the way of your nonsense.
    Suggest you get back to your specialist field of flying saucers.
    You’re a bit touchy.
    :smile: - You can't go saying I'm talking nonsense when you clearly haven't the first clue about it!

    Do I ever tell you you're talking nonsense on the saucers? No, I don't. I read and have a think.
    Perhaps one day I’ll meet you IRL and you can thereafter review my cv and decide if I am more or less qualified than you to talk about risk within the banking system.

    Also on UAPs, you are much like most people and have clearly still done no serious thinking or reading on the recent public discourse in the US. If you had, you would be thinking about it with a more open mind and frankly be amused that some people still think it a topic worthy of stigma or ridicule, bearing in mind the comments even in the last month by for example the serving Administrator of NASA or Michio Kaku, cofounder of string theory.

    It’s taken @kinabalu about 18 months to accept the premise that Lab Leak is plausible. He is a reasonably intelligent guy (but no genius), with a fantastically narrow and settled mind. You have to PRISE it open. I’d give up on UAPs if I were you
    The thing about UAPs is, so what? There is no doubt that there is weird and inexplicable shit going on, but what are we meant to do about it? Assume an Independence Day type alien megaship parks itself in geostationary orbit, and just sits there, what would we do about it? We'd wet our knickers about it and have experts giving it large on the telly about it for 6 months, but when there's no more to say, or do, about it, we'd just crack on with normal life. It's an axiom of advertising that you end up telling your target audience what to do next. UAP fanbois please note.
    Step 1 is to gain insight, of which right now we have very little. Rationalise as best we can any threat level, which is radically different depending upon whether UAP are human origin or “other”. Threat being capability x intent. There’s been a long period already to make this assessment. So let’s hear it please.

    Step 2 is to pass the subject out the hands of the security apparatus and into civilian science. As the US government report describes its “catch all other bin” of categorisation, “pending scientific advances that allowed us to better understand them”. Hence the ground breaking comments by sections of civilian science already emerging in the months since that statement. But we haven’t yet had the transfer moment from Step 1 to Step 2, more is the pity, the data are kept under a cloud of national security and still only being drip fed.

    Step 3, In time, we may then learn how to unleash beneficial technology that would transform global society. Some apes have been observed to spear fish, a skill acquired through observing humans. Despite humans never having tried to teach them that or anything else, nor interfering with their social hierarchies, and being widely apathetic rather than antagonist to their fate.

    Still, we are thinking beings. So perhaps there is a Step 4 that allows us to learn our place in the cosmos, our history and our future. Which I guess would entail some kind of direct interaction with the Pentagon’s “catch all other bin”.

    Unsettling for most people to think about that of course, it’s easier to outsource those questions to scripture writers and focus on day to day life. And probably leads to a happier life all said and done. And if that’s your bag then fine, ignore the dreadnought floating in geostationary orbit. That is what most people are doing.
    Sure. i don't disagree with much of that, I'm just glad you are thinking about it so I don't have to. I just think that the chances of us being in an ape:human ratio to the new guys are vanishingly slim, we are more likely in a cockroach:human ratio. and whether we are or not, we are just gonna have to wait to hear from them. What I firmly do not believe is that joe/the Pentagon are on to the phone to them every night. The progression in the past 5 years has been from the US military knowing nothing, to admitting that they know nothing. Step in the right direction, but no more.
This discussion has been closed.