I have some sympathy for Mike Reader here. I seen no reason why chatgpt shouldn't be used to help shape words into the right order. It's only like getting an underling to do the drafting.
I suspect the numbers might not be all that different if you put "assistant" instead of "ChatGPT".
People want that direct connection to their MP.
People also want the lives of MPs to be unnecessarily austere. You get a similar response about MPs travelling first class. I suspect that is some of the driver.
If they want to travel first class use their own money. Most people hav eto pay out of their own pocket and cannot afford first class. They are a pampered bunch of wasters. Anything above the lowest priced ticket should be personal choice and personal payment.
Pretty shocking opening to the World at One. The UN statement of famine in GAZA uninterrupted. First time ever outside Africa. I hope the Jails in the Hague have enough room.....
Are you an economist? Most people seem to think he did a good job as BoE governor
It's a bit like Rachel. My shares under her watchful eye have today reached an all-time high So I think she's a genius....
Reevesy's made me rich!
At least you have the decency to admit it’s not down to your investment skill. Not quite sure how she did it, as opposed to the respective management teams in the businesses, but she’s in such a hole at the moment she’ll take any credit.
You’re not an economist, you made tampon ads (Ooooh bodyform, bodyform for you-hoo) and did record covers.
No I didn't even get an O'level in economics.....
Sometimes you have to soil yourself for $10,000 a day but what can you do?
Sell the nappies ? Takes all sorts.
I got one art O level. It did nothing for me.
What's the John Bolton story? I don't have access to the rest of the tweet
just some made up bollox because trump hates him as he is intelligent. Given the orange one had a garage full of secret docs it is a joke.
I drove past a house in Stondon Massey nr Brentwood yesterday which had a huge Union Jack flying as well as a billboard saying "i am voting Reform"... have to say it made me think the people living there wouldn't be particularly nice, although if it were any other party I'd avoid them too. You just know they're going to be intense
My previous neighbour had a life-size David Cameron cardboard cut-out in his hallway. If I didn't know TSE lived in Yorkshire I'd have my suspicions.
Obviously apotropaic. Like plastic owls on the roof, and sound recordings of enormous dogs baying and barking. The question is, whom or what was it protecting against?
Ah yes I suppose it could have been to scare away champagne socialists. But given this was Hampstead that would have been quite isolating.
It does show, as @Roger says, the difficulty Reform have in convincing people they are not outright wronguns - I have voted for Farage at every opportunity since 2014, but still, when someone starts banging on about immigration or asylum seekers, I kind of want to get away from them. It happened the other day at Hornchurch FC, a mate of my Dads who wasn't really saying anything I disagreed with. Even when you think mass immigration has been an absolute disaster, as I do, I think it should be something to be said with regret rather than anger, especially if you want to win people over
I saw earlier the Fruits/New/Your Party are opening a Scottish branch so looks like they are going for Holyrood. Good chance they'll get some representation on the lists i'd think
Er, no. No room for them at the inn. Very much doubt they'll do a Tommy Sheridan and break through.
If Alba can't cut it with all the scope there is with disillusioned nationalists, an outfit led by Corbs and Sultana certainly won't. The Scottish Greens are now too well-established.
anyone voting for the mental Scottish Greens should be committed. A bigger bunch of half witted losers would be impossible to find.
(Sorry to steal the rather holy 'betting post' idea, but I did just use 2 *'s.)
So... What actually happened in 1945 onwards that finished up with the Atlee government being tagged as 'oh yes a nice man, did well'?
Atlee was a catastrophe.
I ask because I'm not at all sure that politics makes any sense. I plan to bet accordingly. (Loyal to PB)
WW2 left the country impoverished and exhausted. You can say "it started in Germany" all you like but politics is politics and most of it happened on Churchill's watch.
I saw earlier the Fruits/New/Your Party are opening a Scottish branch so looks like they are going for Holyrood. Good chance they'll get some representation on the lists i'd think
Loving the contortions of people who used to hate John Bolton as a neocon warmonger in the Bush regime, who helped deliver the current state of the middle,east, now trying to go into bat for him as he’s against Trump.
I'm reminded of the people who paused their damning of D. Cummings as a complete liar, to declare him the Sword of Truth, when he turned on Boris Johnson.
No contortion necessary. Bolton's a dickhead, but that's really no justification for turning the FBI on him.
Even Bernie realises that.
John Bolton and I have nothing in common politically.
But last time I heard, in America, people are allowed to criticize the President of the United States without the FBI showing up on their doorstep.
Are you an economist? Most people seem to think he did a good job as BoE governor
It's a bit like Rachel. My shares under her watchful eye have today reached an all-time high So I think she's a genius....
Reevesy's made me rich!
At least you have the decency to admit it’s not down to your investment skill. Not quite sure how she did it, as opposed to the respective management teams in the businesses, but she’s in such a hole at the moment she’ll take any credit.
You’re not an economist, you made tampon ads (Ooooh bodyform, bodyform for you-hoo) and did record covers.
No I didn't even get an O'level in economics.....
Sometimes you have to soil yourself for $10,000 a day but what can you do?
Sell the nappies ? Takes all sorts.
I got one art O level. It did nothing for me.
What's the John Bolton story? I don't have access to the rest of the tweet
just some made up bollox because trump hates him as he is intelligent. Given the orange one had a garage full of secret docs it is a joke.
"For my friends, everything; for my enemies, the law"
I drove past a house in Stondon Massey nr Brentwood yesterday which had a huge Union Jack flying as well as a billboard saying "i am voting Reform"... have to say it made me think the people living there wouldn't be particularly nice, although if it were any other party I'd avoid them too. You just know they're going to be intense
My previous neighbour had a life-size David Cameron cardboard cut-out in his hallway. If I didn't know TSE lived in Yorkshire I'd have my suspicions.
Obviously apotropaic. Like plastic owls on the roof, and sound recordings of enormous dogs baying and barking. The question is, whom or what was it protecting against?
Ah yes I suppose it could have been to scare away champagne socialists. But given this was Hampstead that would have been quite isolating.
It does show, as @Roger says, the difficulty Reform have in convincing people they are not outright wronguns - I have voted for Farage at every opportunity since 2014, but still, when someone starts banging on about immigration or asylum seekers, I kind of want to get away from them. It happened the other day at Hornchurch FC, a mate of my Dads who wasn't really saying anything I disagreed with. Even when you think mass immigration has been an absolute disaster, as I do, I think it should be something to be said with regret rather than anger, especially if you want to win people over
Or worse, hate. I don't envy you seeing your cause disfigured by overt racism.
I saw earlier the Fruits/New/Your Party are opening a Scottish branch so looks like they are going for Holyrood. Good chance they'll get some representation on the lists i'd think
Er, no. No room for them at the inn. Very much doubt they'll do a Tommy Sheridan and break through.
If Alba can't cut it with all the scope there is with disillusioned nationalists, an outfit led by Corbs and Sultana certainly won't. The Scottish Greens are now too well-established.
anyone voting for the mental Scottish Greens should be committed. A bigger bunch of half witted losers would be impossible to find.
Succinctly put and hard to disagree with.
The Greens and Reform are the Yin and Yang of our contemporary immersion into delusory political waters. Hopefully we might resurface at some point.
Pretty shocking opening to the World at One. The UN statement of famine in GAZA uninterrupted. First time ever outside Africa. I hope the Jails in the Hague have enough room.....
The World at One was remarkably well edited today. Simon Jack was excellent. The focus was very much on the famine in Gaza.
If Sarah Montague or Jonny Dimond had been presenting it would have been thirty minutes of wall to wall Lucy Connolly and asylum hotels, followed by fifteen minutes of some gurning interviews with Rupert Lowe, Robert Jenrick and Lee Anderson.
There was a young woman called Lucy Whose thoughts upon migrants were juicy One day she did spout She let it all out And suddenly needed a QC
Update for @Leon, double Union flags are now on 2 sets of zebra crossings in Leighton Buzzard. Must have gone up today. (Nothing to do with me as it happens)
Driving to meet a client in Broxbourne, there were quite a few English/Union Flags. One house even had what looked very much like a loyalist paramilitary flag.
Christ, the deification of Lucy Connolly is really really wearisome. It’s even worse than the demonisation of her as the next Tommy Robinson.
She’s not our Mandela. It’s bloody ridiculous.
She pleaded guilty and was sentenced accordingly.
Meeting with Trump officials is not hugely persuasive that she isn't an alt-right loony.
Her sentence was excessive; I'm not even sure custodial was appropriate, and if it it was it should have been weeks rather than months.
At the same time, she's clearly not a laudable person. I find it strange how anyone can lionise her.
The harsh sentence is a gift for Reform.At the end of the day politics rules, with the added bonus on here of irritating the f*** of all the right people.😂😂😂
Your view from the low life cheap bars on the Costa del Sol where you exchange racist stories with your like minded ex pats while getting pissed on cheap booze is rotting your brain.
I had a funny luch with someone the other day who was telling me about the English and Irish ex pats who he had just been to visit. Not a pretty tale.
This sounds incomprehensible, but what it boils down to is another layer of biological complexity. Decoding the genome was scratching the surface.
Nucleoside diphosphate kinase A (NME1) catalyses its own oligophosphorylation
https://www.nature.com/articles/s41557-025-01915-8 Protein phosphorylation is a central signalling mechanism in eukaryotic cells. The scope of this post-translational modification includes protein pyro- and polyphosphorylation. Here we report the discovery of another mode of phosphorylation: protein oligophosphorylation. Using site-specifically phosphorylated and pyrophosphorylated nucleoside diphosphate kinase A (NME1), the effects of these modifications on enzyme activity were investigated. Phosphorylation, and more so pyrophosphorylation, on Thr94 reduced the nucleoside diphosphate kinase activity. Nevertheless, both phosphoprotein and pyrophosphoprotein catalysed their own oligophosphorylation—up to the formation of a hexaphosphate chain—using ATP as a cofactor. Oligophosphorylation was critically dependent on the catalytic histidine residue His118, and cryogenic electron microscopy analysis of the modified proteins suggests an intramolecular phosphoryl transfer mechanism. Oligophosphorylation of NME1 in biochemical samples, and in cell lysates, was further confirmed using mass spectrometry, and was found to promote a new set of protein interactions. Our results highlight the complex nature of phosphoregulation, and the methods described here provide the opportunity to investigate the impact of this unusual modification in the future.
This sounds incomprehensible, but what it boils down to is another layer of biological complexity. Decoding the genome was scratching the surface.
Nucleoside diphosphate kinase A (NME1) catalyses its own oligophosphorylation
https://www.nature.com/articles/s41557-025-01915-8 Protein phosphorylation is a central signalling mechanism in eukaryotic cells. The scope of this post-translational modification includes protein pyro- and polyphosphorylation. Here we report the discovery of another mode of phosphorylation: protein oligophosphorylation. Using site-specifically phosphorylated and pyrophosphorylated nucleoside diphosphate kinase A (NME1), the effects of these modifications on enzyme activity were investigated. Phosphorylation, and more so pyrophosphorylation, on Thr94 reduced the nucleoside diphosphate kinase activity. Nevertheless, both phosphoprotein and pyrophosphoprotein catalysed their own oligophosphorylation—up to the formation of a hexaphosphate chain—using ATP as a cofactor. Oligophosphorylation was critically dependent on the catalytic histidine residue His118, and cryogenic electron microscopy analysis of the modified proteins suggests an intramolecular phosphoryl transfer mechanism. Oligophosphorylation of NME1 in biochemical samples, and in cell lysates, was further confirmed using mass spectrometry, and was found to promote a new set of protein interactions. Our results highlight the complex nature of phosphoregulation, and the methods described here provide the opportunity to investigate the impact of this unusual modification in the future.
It’s why I much prefer chemistry…
The sheer complexity of living cells that we know about is bad enough. God knows how much more there is to discover.
Update for @Leon, double Union flags are now on 2 sets of zebra crossings in Leighton Buzzard. Must have gone up today. (Nothing to do with me as it happens)
Driving to meet a client in Broxbourne, there were quite a few English/Union Flags. One house even had what looked very much like a loyalist paramilitary flag.
In my best Michael York voice:
Do you still think you can control them?
(Up to now, Farage has done a pretty good job of that. But the stakes, temptations and pressures are quite a bit higher this time round.)
One Trump/Putin possibility we've not sufficiently considered.
Dude just has a serious crush.
Trump: I was just sent a picture from somebody that wants to be there very badly. He has been very respectful of our country but not so respectful of others. I am going to sign this. Vladimir Putin. Who I believe will be coming. That was very nice https://x.com/Acyn/status/1958945613678354894
Not seen any flags locally. Went to Gibside today. Not one. My wife saw a few on a trip to the shops today.
I considered daubing a few St Georges up my window but i remembered i live in a Kermit Green Ward of Norwich and the Polanski Stormtroopers will come and confiscate my crates of veal. I also dont have any St George flags.
So, Reform UK supporters are most opposed, but are also associated with techbros like Elon Musk who champion the technology. Another contradiction within the party?
One Trump/Putin possibility we've not sufficiently considered.
Dude just has a serious crush.
Trump: I was just sent a picture from somebody that wants to be there very badly. He has been very respectful of our country but not so respectful of others. I am going to sign this. Vladimir Putin. Who I believe will be coming. That was very nice https://x.com/Acyn/status/1958945613678354894
I imagine the next step is for Trump to demand, and the shitbag Infantino agreeing, to allow Russia to play in the World Cup despite being banned by UEFA from playing official matches.
I drove past a house in Stondon Massey nr Brentwood yesterday which had a huge Union Jack flying as well as a billboard saying "i am voting Reform"... have to say it made me think the people living there wouldn't be particularly nice, although if it were any other party I'd avoid them too. You just know they're going to be intense
My previous neighbour had a life-size David Cameron cardboard cut-out in his hallway. If I didn't know TSE lived in Yorkshire I'd have my suspicions.
Quite an admission. You didn't live in Chipping Norton next to Clarkson's pig farm?
Not seen any flags locally. Went to Gibside today. Not one. My wife saw a few on a trip to the shops today.
I considered daubing a few St Georges up my window but i remembered i live in a Kermit Green Ward of Norwich and the Polanski Stormtroopers will come and confiscate my crates of veal. I also dont have any St George flags.
Not a problem, just paint the quarters of your Union flag collection in white and you’ve got yourself a load of St George flags.
* Nigel Farage unveils his blueprint for the 'mass deportation' of hundreds of thousands of asylum seekers who come to the UK in small boats
* All those who come to the UK in small boats would be arrested and detained on disused military bases.. They would be barred from leaving until deportation
* Reform will seek to sign return deals with countries including Afghanistan and Eritrea, despite their human rights records
* Farage says Reform will charter five flights a day with an RAF Voyager on standby
* British Overseas Territories such as Ascension Island would be used as a "fallback" to accommodate migrants
* Reform will also seek to sign deals with third countries like Rwanda and Albania
* Reform would introduce new criminal offences for those attempting to return to the UK
* Farage's plan has three parts - leave ECHR and derogate from other international agreements, including UN convention against torture; bring in a British bill of rights; introduce the illegal migration (mass deportation) bill
* Reform says plans will cost £10bn over five years. It claims it will ultimately save taxpayers money
* Plans would face significant legal, political and practical obstacles
* Farage argues it is necessary to deal with the 'massive crisis' posed by illegal migration
* Pressed on what he would do if someone sent to Afghanistan was tortured or killed, Farage said: 'I’m really sorry, but we can’t be responsible for everything that happens in the whole of the world. Who is our priority?
'Is it the safety and security of this country and its people? Or are we worrying about everybody else and foreign courts? That’s what it comes down to. Whose side are you on?'
Update for @Leon, double Union flags are now on 2 sets of zebra crossings in Leighton Buzzard. Must have gone up today. (Nothing to do with me as it happens)
Driving to meet a client in Broxbourne, there were quite a few English/Union Flags. One house even had what looked very much like a loyalist paramilitary flag.
Why do people need to fly flags from their houses ? I understand on public buildings but it seems like one of those American things spilling over here .
I drove past a house in Stondon Massey nr Brentwood yesterday which had a huge Union Jack flying as well as a billboard saying "i am voting Reform"... have to say it made me think the people living there wouldn't be particularly nice, although if it were any other party I'd avoid them too. You just know they're going to be intense
My previous neighbour had a life-size David Cameron cardboard cut-out in his hallway. If I didn't know TSE lived in Yorkshire I'd have my suspicions.
Obviously apotropaic. Like plastic owls on the roof, and sound recordings of enormous dogs baying and barking. The question is, whom or what was it protecting against?
Ah yes I suppose it could have been to scare away champagne socialists. But given this was Hampstead that would have been quite isolating.
It does show, as @Roger says, the difficulty Reform have in convincing people they are not outright wronguns - I have voted for Farage at every opportunity since 2014, but still, when someone starts banging on about immigration or asylum seekers, I kind of want to get away from them. It happened the other day at Hornchurch FC, a mate of my Dads who wasn't really saying anything I disagreed with. Even when you think mass immigration has been an absolute disaster, as I do, I think it should be something to be said with regret rather than anger, especially if you want to win people over
Should this be where the Conservative Party pitches its tent? Right-wing, but rejecting the anger and hate that dominate the populist right.
On thread, clearly only carefully scribed calligraphy responses are acceptable. ChatGPT is so 'completely unacceptable' that if it provided useful information in response to my query i would ignore it to my own detriment to properly show them.
Update for @Leon, double Union flags are now on 2 sets of zebra crossings in Leighton Buzzard. Must have gone up today. (Nothing to do with me as it happens)
Driving to meet a client in Broxbourne, there were quite a few English/Union Flags. One house even had what looked very much like a loyalist paramilitary flag.
I note that
Loyalist Volunteer Force Orange Volunteers Red Hand Commando Red Hand Defenders Ulster Defence Association Ulster Freedom Fighters Ulster Volunteer Force
are on the (Northern Ireland section of the) same proscribed list as Palestine Action. Flying a flag of one of them is illegal.
Update for @Leon, double Union flags are now on 2 sets of zebra crossings in Leighton Buzzard. Must have gone up today. (Nothing to do with me as it happens)
Driving to meet a client in Broxbourne, there were quite a few English/Union Flags. One house even had what looked very much like a loyalist paramilitary flag.
Why do people need to fly flags from their houses ? I understand on public buildings but it seems like one of those American things spilling over here .
It’s more a Northern Irish thing - not because Protestant v Catholic is a big thing in our politics, any more, but because marking out territory is becoming a thing.
Not seen any flags locally. Went to Gibside today. Not one. My wife saw a few on a trip to the shops today.
I considered daubing a few St Georges up my window but i remembered i live in a Kermit Green Ward of Norwich and the Polanski Stormtroopers will come and confiscate my crates of veal. I also dont have any St George flags.
Not a problem, just paint the quarters of your Union flag collection in white and you’ve got yourself a load of St George flags.
Genius. I love it. I knew that bulk order would come in handy
* Nigel Farage unveils his blueprint for the 'mass deportation' of hundreds of thousands of asylum seekers who come to the UK in small boats
* All those who come to the UK in small boats would be arrested and detained on disused military bases.. They would be barred from leaving until deportation
* Reform will seek to sign return deals with countries including Afghanistan and Eritrea, despite their human rights records
* Farage says Reform will charter five flights a day with an RAF Voyager on standby
* British Overseas Territories such as Ascension Island would be used as a "fallback" to accommodate migrants
* Reform will also seek to sign deals with third countries like Rwanda and Albania
* Reform would introduce new criminal offences for those attempting to return to the UK
* Farage's plan has three parts - leave ECHR and derogate from other international agreements, including UN convention against torture; bring in a British bill of rights; introduce the illegal migration (mass deportation) bill
* Reform says plans will cost £10bn over five years. It claims it will ultimately save taxpayers money
* Plans would face significant legal, political and practical obstacles
* Farage argues it is necessary to deal with the 'massive crisis' posed by illegal migration
* Pressed on what he would do if someone sent to Afghanistan was tortured or killed, Farage said: 'I’m really sorry, but we can’t be responsible for everything that happens in the whole of the world. Who is our priority?
'Is it the safety and security of this country and its people? Or are we worrying about everybody else and foreign courts? That’s what it comes down to. Whose side are you on?'
Of course we should all feel safe in the knowledge that a Reform government will be deciding what rights we should have ! Has Farage explained what happens to the GFA , the EU UK trade agreeement and security co-operation ? No just a load of headline grabbing nonsense designed to dupe the public .
One Trump/Putin possibility we've not sufficiently considered.
Dude just has a serious crush.
Trump: I was just sent a picture from somebody that wants to be there very badly. He has been very respectful of our country but not so respectful of others. I am going to sign this. Vladimir Putin. Who I believe will be coming. That was very nice https://x.com/Acyn/status/1958945613678354894
It's beginning to feel a bit like "Whoops Apocalypse".
Not seen any flags locally. Went to Gibside today. Not one. My wife saw a few on a trip to the shops today.
I considered daubing a few St Georges up my window but i remembered i live in a Kermit Green Ward of Norwich and the Polanski Stormtroopers will come and confiscate my crates of veal. I also dont have any St George flags.
Cut a vein and start daubing some tea towels you slacker.
I drove past a house in Stondon Massey nr Brentwood yesterday which had a huge Union Jack flying as well as a billboard saying "i am voting Reform"... have to say it made me think the people living there wouldn't be particularly nice, although if it were any other party I'd avoid them too. You just know they're going to be intense
My previous neighbour had a life-size David Cameron cardboard cut-out in his hallway. If I didn't know TSE lived in Yorkshire I'd have my suspicions.
Obviously apotropaic. Like plastic owls on the roof, and sound recordings of enormous dogs baying and barking. The question is, whom or what was it protecting against?
Ah yes I suppose it could have been to scare away champagne socialists. But given this was Hampstead that would have been quite isolating.
It does show, as @Roger says, the difficulty Reform have in convincing people they are not outright wronguns - I have voted for Farage at every opportunity since 2014, but still, when someone starts banging on about immigration or asylum seekers, I kind of want to get away from them. It happened the other day at Hornchurch FC, a mate of my Dads who wasn't really saying anything I disagreed with. Even when you think mass immigration has been an absolute disaster, as I do, I think it should be something to be said with regret rather than anger, especially if you want to win people over
Should this be where the Conservative Party pitches its tent? Right-wing, but rejecting the anger and hate that dominate the populist right.
I saw earlier the Fruits/New/Your Party are opening a Scottish branch so looks like they are going for Holyrood. Good chance they'll get some representation on the lists i'd think
Er, no. No room for them at the inn. Very much doubt they'll do a Tommy Sheridan and break through.
If Alba can't cut it with all the scope there is with disillusioned nationalists, an outfit led by Corbs and Sultana certainly won't. The Scottish Greens are now too well-established.
I'll have to agree to disagree. I think they could hit 5 to 7% in a region and pick up a list seat. They've more chance in Scotland than in Wales certainly
Yes, its roughly 6% needed for a list seat. They may be competitive in Glasgow and Edinburgh, that's about it. I dont think they'll take a seat, agree with others it's a very crowded field now. Their views will be almost identical to the Greens, who are now polling well enough to be scooping up to 2 MSPs per region. They'd better change the name from "Your Party" or it'll be bottom of the ballot paper, list parties are ranked alphabetically
Not seen any flags locally. Went to Gibside today. Not one. My wife saw a few on a trip to the shops today.
I considered daubing a few St Georges up my window but i remembered i live in a Kermit Green Ward of Norwich and the Polanski Stormtroopers will come and confiscate my crates of veal. I also dont have any St George flags.
Cut a vein and start daubing some tea towels you slacker.
My tea towels have pussy cats on them, they dont like blood
One Trump/Putin possibility we've not sufficiently considered.
Dude just has a serious crush.
Trump: I was just sent a picture from somebody that wants to be there very badly. He has been very respectful of our country but not so respectful of others. I am going to sign this. Vladimir Putin. Who I believe will be coming. That was very nice https://x.com/Acyn/status/1958945613678354894
It's beginning to feel a bit like "Whoops Apocalypse".
That’s very insulting to our glorious PM and his plan for reducing unemployment.
Christ, the deification of Lucy Connolly is really really wearisome. It’s even worse than the demonisation of her as the next Tommy Robinson.
She’s not our Mandela. It’s bloody ridiculous.
She pleaded guilty and was sentenced accordingly.
Blasphemer!!!!
As someone said online she’s rapidly becoming a right wing George Floyd,
But of course. In fact that's a brilliant comparison
*files it away carefully for Gazette editor*
All causes need a martyr. On examination, these martyrs are nearly always deeply flawed, but by then it doesn't matter, the narrative is put in place
Geo Floyd was a hideous career criminal, guilty of terrible things, yet the surge of emotion around his ugly death was sufficient to get him sanctified. For a while. In retrospect, I am not even sure he was murdered. I suspect he died because of his drug use more than the clearly unthinking and brutal copper
But no one cares now. The story is established, even as the emotions ebb
Lucy C is not as extremely bad as Floyd nor as extremely beatified as him, but there are definite parellels, and she will suffice as a martyr for the alt.right cause
Update for @Leon, double Union flags are now on 2 sets of zebra crossings in Leighton Buzzard. Must have gone up today. (Nothing to do with me as it happens)
Driving to meet a client in Broxbourne, there were quite a few English/Union Flags. One house even had what looked very much like a loyalist paramilitary flag.
Why do people need to fly flags from their houses ? I understand on public buildings but it seems like one of those American things spilling over here .
* Nigel Farage unveils his blueprint for the 'mass deportation' of hundreds of thousands of asylum seekers who come to the UK in small boats
* All those who come to the UK in small boats would be arrested and detained on disused military bases.. They would be barred from leaving until deportation
* Reform will seek to sign return deals with countries including Afghanistan and Eritrea, despite their human rights records
* Farage says Reform will charter five flights a day with an RAF Voyager on standby
* British Overseas Territories such as Ascension Island would be used as a "fallback" to accommodate migrants
* Reform will also seek to sign deals with third countries like Rwanda and Albania
* Reform would introduce new criminal offences for those attempting to return to the UK
* Farage's plan has three parts - leave ECHR and derogate from other international agreements, including UN convention against torture; bring in a British bill of rights; introduce the illegal migration (mass deportation) bill
* Reform says plans will cost £10bn over five years. It claims it will ultimately save taxpayers money
* Plans would face significant legal, political and practical obstacles
* Farage argues it is necessary to deal with the 'massive crisis' posed by illegal migration
* Pressed on what he would do if someone sent to Afghanistan was tortured or killed, Farage said: 'I’m really sorry, but we can’t be responsible for everything that happens in the whole of the world. Who is our priority?
'Is it the safety and security of this country and its people? Or are we worrying about everybody else and foreign courts? That’s what it comes down to. Whose side are you on?'
Update for @Leon, double Union flags are now on 2 sets of zebra crossings in Leighton Buzzard. Must have gone up today. (Nothing to do with me as it happens)
Driving to meet a client in Broxbourne, there were quite a few English/Union Flags. One house even had what looked very much like a loyalist paramilitary flag.
Why do people need to fly flags from their houses ? I understand on public buildings but it seems like one of those American things spilling over here .
I bring heartening news for our resident patriots. The A2 and M2 all the way from South East London to Faversham is festooned with British and English flags.
The Union flags were looking quite pretty, backlit and glowing in the lowering early autumn sun, as I returned from the vineyard this evening.
Update for @Leon, double Union flags are now on 2 sets of zebra crossings in Leighton Buzzard. Must have gone up today. (Nothing to do with me as it happens)
Driving to meet a client in Broxbourne, there were quite a few English/Union Flags. One house even had what looked very much like a loyalist paramilitary flag.
I note that
Loyalist Volunteer Force Orange Volunteers Red Hand Commando Red Hand Defenders Ulster Defence Association Ulster Freedom Fighters Ulster Volunteer Force
are on the (Northern Ireland section of the) same proscribed list as Palestine Action. Flying a flag of one of them is illegal.
The flag in question seemed similar to ones I’ve seen in Larne, orange and purple, with the cross of St.George.
I bring heartening news for our resident patriots. The A2 and M2 all the way from South East London to Faversham is festooned with British and English flags.
The Union flags were looking quite pretty, backlit and glowing in the lowering early autumn sun, as I returned from the vineyard this evening.
We must continue this flag shagging effort, for years, to instil the necessary emotions in the varous peoples of Great Britain
I bring heartening news for our resident patriots. The A2 and M2 all the way from South East London to Faversham is festooned with British and English flags.
The Union flags were looking quite pretty, backlit and glowing in the lowering early autumn sun, as I returned from the vineyard this evening.
This sounds incomprehensible, but what it boils down to is another layer of biological complexity. Decoding the genome was scratching the surface.
Nucleoside diphosphate kinase A (NME1) catalyses its own oligophosphorylation
https://www.nature.com/articles/s41557-025-01915-8 Protein phosphorylation is a central signalling mechanism in eukaryotic cells. The scope of this post-translational modification includes protein pyro- and polyphosphorylation. Here we report the discovery of another mode of phosphorylation: protein oligophosphorylation. Using site-specifically phosphorylated and pyrophosphorylated nucleoside diphosphate kinase A (NME1), the effects of these modifications on enzyme activity were investigated. Phosphorylation, and more so pyrophosphorylation, on Thr94 reduced the nucleoside diphosphate kinase activity. Nevertheless, both phosphoprotein and pyrophosphoprotein catalysed their own oligophosphorylation—up to the formation of a hexaphosphate chain—using ATP as a cofactor. Oligophosphorylation was critically dependent on the catalytic histidine residue His118, and cryogenic electron microscopy analysis of the modified proteins suggests an intramolecular phosphoryl transfer mechanism. Oligophosphorylation of NME1 in biochemical samples, and in cell lysates, was further confirmed using mass spectrometry, and was found to promote a new set of protein interactions. Our results highlight the complex nature of phosphoregulation, and the methods described here provide the opportunity to investigate the impact of this unusual modification in the future.
Mm, clear enough. Never heard of hexaphosphate in phosphoprotein but I am very rusty.
I bring heartening news for our resident patriots. The A2 and M2 all the way from South East London to Faversham is festooned with British and English flags.
The Union flags were looking quite pretty, backlit and glowing in the lowering early autumn sun, as I returned from the vineyard this evening.
Update for @Leon, double Union flags are now on 2 sets of zebra crossings in Leighton Buzzard. Must have gone up today. (Nothing to do with me as it happens)
Driving to meet a client in Broxbourne, there were quite a few English/Union Flags. One house even had what looked very much like a loyalist paramilitary flag.
I note that
Loyalist Volunteer Force Orange Volunteers Red Hand Commando Red Hand Defenders Ulster Defence Association Ulster Freedom Fighters Ulster Volunteer Force
are on the (Northern Ireland section of the) same proscribed list as Palestine Action. Flying a flag of one of them is illegal.
They’re the sort of evil fascist scumbags that would support Netanyahu and Putin. (Waits for a defence from Alanbrooke.)
This sounds incomprehensible, but what it boils down to is another layer of biological complexity. Decoding the genome was scratching the surface.
Nucleoside diphosphate kinase A (NME1) catalyses its own oligophosphorylation
https://www.nature.com/articles/s41557-025-01915-8 Protein phosphorylation is a central signalling mechanism in eukaryotic cells. The scope of this post-translational modification includes protein pyro- and polyphosphorylation. Here we report the discovery of another mode of phosphorylation: protein oligophosphorylation. Using site-specifically phosphorylated and pyrophosphorylated nucleoside diphosphate kinase A (NME1), the effects of these modifications on enzyme activity were investigated. Phosphorylation, and more so pyrophosphorylation, on Thr94 reduced the nucleoside diphosphate kinase activity. Nevertheless, both phosphoprotein and pyrophosphoprotein catalysed their own oligophosphorylation—up to the formation of a hexaphosphate chain—using ATP as a cofactor. Oligophosphorylation was critically dependent on the catalytic histidine residue His118, and cryogenic electron microscopy analysis of the modified proteins suggests an intramolecular phosphoryl transfer mechanism. Oligophosphorylation of NME1 in biochemical samples, and in cell lysates, was further confirmed using mass spectrometry, and was found to promote a new set of protein interactions. Our results highlight the complex nature of phosphoregulation, and the methods described here provide the opportunity to investigate the impact of this unusual modification in the future.
Mm, clear enough. Never heard of hexaphosphate in phosphoprotein but I am very rusty.
* Nigel Farage unveils his blueprint for the 'mass deportation' of hundreds of thousands of asylum seekers who come to the UK in small boats
* All those who come to the UK in small boats would be arrested and detained on disused military bases.. They would be barred from leaving until deportation
* Reform will seek to sign return deals with countries including Afghanistan and Eritrea, despite their human rights records
* Farage says Reform will charter five flights a day with an RAF Voyager on standby
* British Overseas Territories such as Ascension Island would be used as a "fallback" to accommodate migrants
* Reform will also seek to sign deals with third countries like Rwanda and Albania
* Reform would introduce new criminal offences for those attempting to return to the UK
* Farage's plan has three parts - leave ECHR and derogate from other international agreements, including UN convention against torture; bring in a British bill of rights; introduce the illegal migration (mass deportation) bill
* Reform says plans will cost £10bn over five years. It claims it will ultimately save taxpayers money
* Plans would face significant legal, political and practical obstacles
* Farage argues it is necessary to deal with the 'massive crisis' posed by illegal migration
* Pressed on what he would do if someone sent to Afghanistan was tortured or killed, Farage said: 'I’m really sorry, but we can’t be responsible for everything that happens in the whole of the world. Who is our priority?
'Is it the safety and security of this country and its people? Or are we worrying about everybody else and foreign courts? That’s what it comes down to. Whose side are you on?'
Update for @Leon, double Union flags are now on 2 sets of zebra crossings in Leighton Buzzard. Must have gone up today. (Nothing to do with me as it happens)
Driving to meet a client in Broxbourne, there were quite a few English/Union Flags. One house even had what looked very much like a loyalist paramilitary flag.
I note that
Loyalist Volunteer Force Orange Volunteers Red Hand Commando Red Hand Defenders Ulster Defence Association Ulster Freedom Fighters Ulster Volunteer Force
are on the (Northern Ireland section of the) same proscribed list as Palestine Action. Flying a flag of one of them is illegal.
The flag in question seemed similar to ones I’ve seen in Larne, orange and purple, with the cross of St.George.
I’ve got a couple of questions. You’re of Indian descent, and British, how do the Union Jack and Cross of St George make you feel, if I may rudely inquire?
You’re under no obligation to answer but my interest is sincere
Do you feel patriotic? Neutral? Sad? Angry about the empire?
And does it matter where you see them? Is it intimidating if you see them outside a pub or a shop or simply meaningless?
And, finally, do you have different emotional reactions to the two flags? There are suggestions on X that the England flag is now seen as the more “provocative”
Good evening, @Leon. Good thanks, hope you are too.
Apologies for the late reply. Was out with my Mum on a photo-walk (er, she's a member of not one but two of the local east London/Essex borders camera clubs), starting on Oxford St, Regent St, Carnaby St, Chinatown and Trafalgar. Let's just say the West End was rather busy, to put it mildly!
Anyway, in answer to your questions, and I feel I must apologise for writing an essay, but anyway: Nope, don't think your rude at all for asking about the flags! As for the Union Jack and St George's Cross, I do feel patriotic for both really. Certainly don't have a problem with with either of them. As you in this morning's thread, I saw a row of five flags (one row of many, in fact) hung across Oxford Street, and was eager to show all of you a picture on PB. And it's always nice to see pubs with the flags too (yes, we still have half a dozen or so in da North Ilford Ghetto!).
I think I have stated a couple of times on here that the most egregious, cruellest, pernicious aspect of the Empire was that the Powers That Be taught Indians how to play boring Cricket instead of Football. Imagine - India could now be the sporting Brazil of Asia! And I suppose Pakistan could be Argentina!
For me, England is my home, I've lived here ever since I was 4 months old. I do go back to India every couple of years, but I don't have any real attachment to the place. My language is English, and I have oft stated on here that I regard English as the best language in the world. One of the most disappointing things I find about India is the lack of civic sense in most parts of the country. Most obviously, the huge piles of litter beside train tracks and roads. No real neatness, as if tidiness isn't part of the culture. I could go on, but I digress!
Anyway, to conclude, perhaps very controversially, and this will probably upset a few PBers, I think that being English is a question of attitude, and not just a question of birth. Hope you find the above scrawlings interesting!
I bring heartening news for our resident patriots. The A2 and M2 all the way from South East London to Faversham is festooned with British and English flags.
The Union flags were looking quite pretty, backlit and glowing in the lowering early autumn sun, as I returned from the vineyard this evening.
We must continue this flag shagging effort, for years, to instil the necessary emotions in the varous peoples of Great Britain
It’s making me want to fly a saltire in the front garden, just to piss of the local unionists.
Update for @Leon, double Union flags are now on 2 sets of zebra crossings in Leighton Buzzard. Must have gone up today. (Nothing to do with me as it happens)
Driving to meet a client in Broxbourne, there were quite a few English/Union Flags. One house even had what looked very much like a loyalist paramilitary flag.
Why do people need to fly flags from their houses ? I understand on public buildings but it seems like one of those American things spilling over here .
It is all about intent.
If flying a flag is done to celebrate or anticipate sporting achievement, fine. If to celebrate a national occasion, such as a Royal Jubilee or Wedding, St George's Day or anniversary of VJ day, also fine.
If it is done to intimidate or frighten, such as EDL marches, then not fine.
The same of course goes for other flags of course, including Palestine, Israel, Confederate, Betsy Ross, Soviet etc.
I’ve got a couple of questions. You’re of Indian descent, and British, how do the Union Jack and Cross of St George make you feel, if I may rudely inquire?
You’re under no obligation to answer but my interest is sincere
Do you feel patriotic? Neutral? Sad? Angry about the empire?
And does it matter where you see them? Is it intimidating if you see them outside a pub or a shop or simply meaningless?
And, finally, do you have different emotional reactions to the two flags? There are suggestions on X that the England flag is now seen as the more “provocative”
Good evening, @Leon. Good thanks, hope you are too.
Apologies for the late reply. Was out with my Mum on a photo-walk (er, she's a member of not one but two of the local east London/Essex borders camera clubs), starting on Oxford St, Regent St, Carnaby St, Chinatown and Trafalgar. Let's just say the West End was rather busy, to put it mildly!
Anyway, in answer to your questions, and I feel I must apologise for writing an essay, but anyway: Nope, don't think your rude at all for asking about the flags! As for the Union Jack and St George's Cross, I do feel patriotic for both really. Certainly don't have a problem with with either of them. As you in this morning's thread, I saw a row of five flags (one row of many, in fact) hung across Oxford Street, and was eager to show all of you a picture on PB. And it's always nice to see pubs with the flags too (yes, we still have half a dozen or so in da North Ilford Ghetto!).
I think I have stated a couple of times on here that the most egregious, cruellest, pernicious aspect of the Empire was that the Powers That Be taught Indians how to play boring Cricket instead of Football. Imagine - India could now be the sporting Brazil of Asia! And I suppose Pakistan could be Argentina!
For me, England is my home, I've lived here ever since I was 4 months old. I do go back to India every couple of years, but I don't have any real attachment to the place. My language is English, and I have oft stated on here that I regard English as the best language in the world. One of the most disappointing things I find about India is the lack of civic sense in most parts of the country. Most obviously, the huge piles of litter beside train tracks and roads. No real neatness, as if tidiness isn't part of the culture. I could go on, but I digress!
Anyway, to conclude, perhaps very controversially, and this will probably upset a few PBers, I think that being English is a question of attitude, and not just a question of birth. Hope you find the above scrawlings interesting!
I think you are 100% correct with that - it’s not about birth, it’s about what you feel you are. I had a mate in NZ a bit like you. In his case he was born in U.K. but lived in NZ since very young. He was 100% a Kiwi, not a Brit.
Come on, who else is actually writing all the text in their own emails...I am certainly not. And I bet loads of those polled have used it to do the same.
If your email is that long no one is reading it and it should be replaced by a shared doc for comments, or a Teams call. The same goes for short ones tbh, those should be Teams messages.
I only email if it needs to be on the corporate record. I feel quite strongly about this given the countless hours of wading through pointless emails. (Sorry, might be a generational thing).
I am noted for my pith in emails.
I regularly send one word emails.
You appear to be taking the pith. Besides, Arkell v Pressdram is three words.
Nah, I mentioned last week that one time at work we in a protracted dispute with an external party with letters via email getting sent regularly.
One time their side sent me a 9,000 word letter, I read it, then replied with ‘noted’ and their guy replied with some very unprofessional language, they never recovered.
My smugness levels hit a new peak and I was even more unbearable for weeks after.
I have occasionally replied to people with I refer you to Pressdram’s reply in Arkell v Pressdram
One Trump/Putin possibility we've not sufficiently considered.
Dude just has a serious crush.
Trump: I was just sent a picture from somebody that wants to be there very badly. He has been very respectful of our country but not so respectful of others. I am going to sign this. Vladimir Putin. Who I believe will be coming. That was very nice https://x.com/Acyn/status/1958945613678354894
Putin just blew up an American factory in Ukraine. Serious question: is Trump weaker than Corbyn when it comes to Russia?
I bring heartening news for our resident patriots. The A2 and M2 all the way from South East London to Faversham is festooned with British and English flags.
The Union flags were looking quite pretty, backlit and glowing in the lowering early autumn sun, as I returned from the vineyard this evening.
We must continue this flag shagging effort, for years, to instil the necessary emotions in the varous peoples of Great Britain
It’s making me want to fly a saltire in the front garden, just to piss of the local unionists.
I'd fly the flag of the Sretensky district of Russia. Not because of any support for the locale, but it's just a great flag.
Update for @Leon, double Union flags are now on 2 sets of zebra crossings in Leighton Buzzard. Must have gone up today. (Nothing to do with me as it happens)
Driving to meet a client in Broxbourne, there were quite a few English/Union Flags. One house even had what looked very much like a loyalist paramilitary flag.
Why do people need to fly flags from their houses ? I understand on public buildings but it seems like one of those American things spilling over here .
It’s more a Northern Irish thing - not because Protestant v Catholic is a big thing in our politics, any more, but because marking out territory is becoming a thing.
Can't we just piss against lampposts like our canine friends?
Update for @Leon, double Union flags are now on 2 sets of zebra crossings in Leighton Buzzard. Must have gone up today. (Nothing to do with me as it happens)
Driving to meet a client in Broxbourne, there were quite a few English/Union Flags. One house even had what looked very much like a loyalist paramilitary flag.
Why do people need to fly flags from their houses ? I understand on public buildings but it seems like one of those American things spilling over here .
It is all about intent.
If flying a flag is done to celebrate or anticipate sporting achievement, fine. If to celebrate a national occasion, such as a Royal Jubilee or Wedding, St George's Day or anniversary of VJ day, also fine.
If it is done to intimidate or frighten, such as EDL marches, then not fine.
The same of course goes for other flags of course, including Palestine, Israel, Confederate, Betsy Ross, Soviet etc.
The sad thing is that the people who want to fly flags to intimidate will make the people who want to fly flags to celebrate to decide not to fly their flags. That’s a form of bullying.
Update for @Leon, double Union flags are now on 2 sets of zebra crossings in Leighton Buzzard. Must have gone up today. (Nothing to do with me as it happens)
Driving to meet a client in Broxbourne, there were quite a few English/Union Flags. One house even had what looked very much like a loyalist paramilitary flag.
Why do people need to fly flags from their houses ? I understand on public buildings but it seems like one of those American things spilling over here .
I always find it handy for when I'm walking down the street and I forget which country I'm in.
Increasingly the right is completely out of control and has no self-restraining mechanisms left. Certainly lost touch with what was conservativism as say Oakeshott or Burke or Scruton would understand it.
It is a race to see who can be first to just say 'burn it all down, every last fucking thing. Burn it.'
I bring heartening news for our resident patriots. The A2 and M2 all the way from South East London to Faversham is festooned with British and English flags.
The Union flags were looking quite pretty, backlit and glowing in the lowering early autumn sun, as I returned from the vineyard this evening.
We must continue this flag shagging effort, for years, to instil the necessary emotions in the varous peoples of Great Britain
It’s making me want to fly a saltire in the front garden, just to piss of the local unionists.
I'd fly the flag of the Sretensky district of Russia. Not because of any support for the locale, but it's just a great flag.
The Northumberland flag is pretty good. I would fly it in my garden, based only on it being a cool flag and Northumberland being a wonderful place.
I’ve got a couple of questions. You’re of Indian descent, and British, how do the Union Jack and Cross of St George make you feel, if I may rudely inquire?
You’re under no obligation to answer but my interest is sincere
Do you feel patriotic? Neutral? Sad? Angry about the empire?
And does it matter where you see them? Is it intimidating if you see them outside a pub or a shop or simply meaningless?
And, finally, do you have different emotional reactions to the two flags? There are suggestions on X that the England flag is now seen as the more “provocative”
Good evening, @Leon. Good thanks, hope you are too.
Apologies for the late reply. Was out with my Mum on a photo-walk (er, she's a member of not one but two of the local east London/Essex borders camera clubs), starting on Oxford St, Regent St, Carnaby St, Chinatown and Trafalgar. Let's just say the West End was rather busy, to put it mildly!
Anyway, in answer to your questions, and I feel I must apologise for writing an essay, but anyway: Nope, don't think your rude at all for asking about the flags! As for the Union Jack and St George's Cross, I do feel patriotic for both really. Certainly don't have a problem with with either of them. As you in this morning's thread, I saw a row of five flags (one row of many, in fact) hung across Oxford Street, and was eager to show all of you a picture on PB. And it's always nice to see pubs with the flags too (yes, we still have half a dozen or so in da North Ilford Ghetto!).
I think I have stated a couple of times on here that the most egregious, cruellest, pernicious aspect of the Empire was that the Powers That Be taught Indians how to play boring Cricket instead of Football. Imagine - India could now be the sporting Brazil of Asia! And I suppose Pakistan could be Argentina!
For me, England is my home, I've lived here ever since I was 4 months old. I do go back to India every couple of years, but I don't have any real attachment to the place. My language is English, and I have oft stated on here that I regard English as the best language in the world. One of the most disappointing things I find about India is the lack of civic sense in most parts of the country. Most obviously, the huge piles of litter beside train tracks and roads. No real neatness, as if tidiness isn't part of the culture. I could go on, but I digress!
Anyway, to conclude, perhaps very controversially, and this will probably upset a few PBers, I think that being English is a question of attitude, and not just a question of birth. Hope you find the above scrawlings interesting!
Increasingly the right is completely out of control and has no self-restraining mechanisms left. Certainly lost touch with what was conservativism as say Oakeshott or Burke or Scruton would understand it.
It is a race to see who can be first to just say 'burn it all down, every last fucking thing. Burn it.'
Update for @Leon, double Union flags are now on 2 sets of zebra crossings in Leighton Buzzard. Must have gone up today. (Nothing to do with me as it happens)
Driving to meet a client in Broxbourne, there were quite a few English/Union Flags. One house even had what looked very much like a loyalist paramilitary flag.
I note that
Loyalist Volunteer Force Orange Volunteers Red Hand Commando Red Hand Defenders Ulster Defence Association Ulster Freedom Fighters Ulster Volunteer Force
are on the (Northern Ireland section of the) same proscribed list as Palestine Action. Flying a flag of one of them is illegal.
They’re the sort of evil fascist scumbags that would support Netanyahu and Putin. (Waits for a defence from Alanbrooke.)
Nonsense. They would be too busy "taxing" drug dealers to do that. Plus there is no way that anyone in the RHD could pronounce Netanyahu - they would probably break something in their throats and choke to death.
Update for @Leon, double Union flags are now on 2 sets of zebra crossings in Leighton Buzzard. Must have gone up today. (Nothing to do with me as it happens)
Driving to meet a client in Broxbourne, there were quite a few English/Union Flags. One house even had what looked very much like a loyalist paramilitary flag.
Why do people need to fly flags from their houses ? I understand on public buildings but it seems like one of those American things spilling over here .
It’s more a Northern Irish thing - not because Protestant v Catholic is a big thing in our politics, any more, but because marking out territory is becoming a thing.
Can't we just piss against lampposts like our canine friends?
I already do, but only after a few pints of Old Peculier.
Update for @Leon, double Union flags are now on 2 sets of zebra crossings in Leighton Buzzard. Must have gone up today. (Nothing to do with me as it happens)
Driving to meet a client in Broxbourne, there were quite a few English/Union Flags. One house even had what looked very much like a loyalist paramilitary flag.
Why do people need to fly flags from their houses ? I understand on public buildings but it seems like one of those American things spilling over here .
I always find it handy for when I'm walking down the street and I forget which country I'm in.
Which is caused by Richard Rogers and his spawn perpetrating architecture all over the world. That bland-but-significantly-styled-building thing.
I’ve got a couple of questions. You’re of Indian descent, and British, how do the Union Jack and Cross of St George make you feel, if I may rudely inquire?
You’re under no obligation to answer but my interest is sincere
Do you feel patriotic? Neutral? Sad? Angry about the empire?
And does it matter where you see them? Is it intimidating if you see them outside a pub or a shop or simply meaningless?
And, finally, do you have different emotional reactions to the two flags? There are suggestions on X that the England flag is now seen as the more “provocative”
Good evening, @Leon. Good thanks, hope you are too.
Apologies for the late reply. Was out with my Mum on a photo-walk (er, she's a member of not one but two of the local east London/Essex borders camera clubs), starting on Oxford St, Regent St, Carnaby St, Chinatown and Trafalgar. Let's just say the West End was rather busy, to put it mildly!
Anyway, in answer to your questions, and I feel I must apologise for writing an essay, but anyway: Nope, don't think your rude at all for asking about the flags! As for the Union Jack and St George's Cross, I do feel patriotic for both really. Certainly don't have a problem with with either of them. As you in this morning's thread, I saw a row of five flags (one row of many, in fact) hung across Oxford Street, and was eager to show all of you a picture on PB. And it's always nice to see pubs with the flags too (yes, we still have half a dozen or so in da North Ilford Ghetto!).
I think I have stated a couple of times on here that the most egregious, cruellest, pernicious aspect of the Empire was that the Powers That Be taught Indians how to play boring Cricket instead of Football. Imagine - India could now be the sporting Brazil of Asia! And I suppose Pakistan could be Argentina!
For me, England is my home, I've lived here ever since I was 4 months old. I do go back to India every couple of years, but I don't have any real attachment to the place. My language is English, and I have oft stated on here that I regard English as the best language in the world. One of the most disappointing things I find about India is the lack of civic sense in most parts of the country. Most obviously, the huge piles of litter beside train tracks and roads. No real neatness, as if tidiness isn't part of the culture. I could go on, but I digress!
Anyway, to conclude, perhaps very controversially, and this will probably upset a few PBers, I think that being English is a question of attitude, and not just a question of birth. Hope you find the above scrawlings interesting!
As I have said before. Some of the most English people I ever met were not born here but came here at a young age. Nor were they white. Englishness is a matter of culture and, as you so rightly say, attitude. In my view birthplace and ethnicity have nothing to do with it.
Increasingly the right is completely out of control and has no self-restraining mechanisms left. Certainly lost touch with what was conservativism as say Oakeshott or Burke or Scruton would understand it.
It is a race to see who can be first to just say 'burn it all down, every last fucking thing. Burn it.'
It's hard to spot what attracted Carswell to Alabama isn't it?
Carswell went nuts long ago. Even one or two posters on here with 'robust views on immigration' got queasy at his calls for the enforced repatriation of Muslims in Britain.
I bring heartening news for our resident patriots. The A2 and M2 all the way from South East London to Faversham is festooned with British and English flags.
The Union flags were looking quite pretty, backlit and glowing in the lowering early autumn sun, as I returned from the vineyard this evening.
We must continue this flag shagging effort, for years, to instil the necessary emotions in the varous peoples of Great Britain
It’s making me want to fly a saltire in the front garden, just to piss of the local unionists.
I'd fly the flag of the Sretensky district of Russia. Not because of any support for the locale, but it's just a great flag.
The Northumberland flag is pretty good. I would fly it in my garden, based only on it being a cool flag and Northumberland being a wonderful place.
Northumberland is a top flag. I also like Warks and Staffs.
Lincolnshire flag is hideous. Unsurprisingly it was selected via an online BBC vote.
Increasingly the right is completely out of control and has no self-restraining mechanisms left. Certainly lost touch with what was conservativism as say Oakeshott or Burke or Scruton would understand it.
It is a race to see who can be first to just say 'burn it all down, every last fucking thing. Burn it.'
It's hard to spot what attracted Carswell to Alabama isn't it?
There was a time when Carswell was quite interesting and had ideas. He is an example of what has happened to the right. No wonder the Spectator feels a beleagured mess and the Telegraph an unprincipled rag.
Where, I wonder, is the next set of decent thoughts in the Burkean tradition going to come from?
I bring heartening news for our resident patriots. The A2 and M2 all the way from South East London to Faversham is festooned with British and English flags.
The Union flags were looking quite pretty, backlit and glowing in the lowering early autumn sun, as I returned from the vineyard this evening.
We must continue this flag shagging effort, for years, to instil the necessary emotions in the varous peoples of Great Britain
It’s making me want to fly a saltire in the front garden, just to piss of the local unionists.
I think more flags should be flown.
I remember seeing a Somalian flag one time when driving through the Scottish Borders. Most diverting!
I'd consider flying a Hapsburg flag, but everyone would assume I had a Kilkenny flag rotated 90 degrees.
Increasingly the right is completely out of control and has no self-restraining mechanisms left. Certainly lost touch with what was conservativism as say Oakeshott or Burke or Scruton would understand it.
It is a race to see who can be first to just say 'burn it all down, every last fucking thing. Burn it.'
What's notable here isn't the attack on a judge - UK judges are actively political and it's way past the time when they could claim to be inviolable. It's the casual assumption of a reverse colonial authority wielded by the USA over Britain. This should be strongly resisted. Carswell I'm sorry to say is a prat. Always has been.
Increasingly the right is completely out of control and has no self-restraining mechanisms left. Certainly lost touch with what was conservativism as say Oakeshott or Burke or Scruton would understand it. Wh It is a race to see who can be first to just say 'burn it all down, every last fucking thing. Burn it.'
Dunno. Scruton was pretty radical towards the end. Probably because the Left successfully cancelled him with a screed of lies - well done George Eaton of the New Statesman, you utter ****** - and then he died of cancer shortly after
I went to some of Scruton's lectures at Birkbeck in the 80s as a callow smack addict Philosophy student. What a mind
His guide to Modern Philosophy is perhaps the smartest book I have ever read: in that it took the most difficult and arcane of ideas (but important) and made them legible to an intelligent layman. That is an amazing gift, very very few have it
Also he liked sex and wine. He was the last great English intellectual. Yes I am a fanboi. RIP
This sounds incomprehensible, but what it boils down to is another layer of biological complexity. Decoding the genome was scratching the surface.
Nucleoside diphosphate kinase A (NME1) catalyses its own oligophosphorylation
https://www.nature.com/articles/s41557-025-01915-8 Protein phosphorylation is a central signalling mechanism in eukaryotic cells. The scope of this post-translational modification includes protein pyro- and polyphosphorylation. Here we report the discovery of another mode of phosphorylation: protein oligophosphorylation. Using site-specifically phosphorylated and pyrophosphorylated nucleoside diphosphate kinase A (NME1), the effects of these modifications on enzyme activity were investigated. Phosphorylation, and more so pyrophosphorylation, on Thr94 reduced the nucleoside diphosphate kinase activity. Nevertheless, both phosphoprotein and pyrophosphoprotein catalysed their own oligophosphorylation—up to the formation of a hexaphosphate chain—using ATP as a cofactor. Oligophosphorylation was critically dependent on the catalytic histidine residue His118, and cryogenic electron microscopy analysis of the modified proteins suggests an intramolecular phosphoryl transfer mechanism. Oligophosphorylation of NME1 in biochemical samples, and in cell lysates, was further confirmed using mass spectrometry, and was found to promote a new set of protein interactions. Our results highlight the complex nature of phosphoregulation, and the methods described here provide the opportunity to investigate the impact of this unusual modification in the future.
Mm, clear enough. Never heard of hexaphosphate in phosphoprotein but I am very rusty.
Comments
Bolton's a dickhead, but that's really no justification for turning the FBI on him.
Even Bernie realises that.
John Bolton and I have nothing in common politically.
But last time I heard, in America, people are allowed to criticize the President of the United States without the FBI showing up on their doorstep.
Just another step in Trump’s march toward authoritarianism.
https://x.com/BernieSanders/status/1958913008505086132
(They are both skiing* stories)
*apres
The Greens and Reform are the Yin and Yang of our contemporary immersion into delusory political waters. Hopefully we might resurface at some point.
But one of the endearing things about humans is that we can, and do, know things that just ain't so.
And that's true of all of us
England 33
USA 7
45 mins
https://www.bbc.co.uk/sport/rugby-union/live/cqle920zn3qt
Am travelling to Manchester by road tomorrow. Will report.
I had a funny luch with someone the other day who was telling me about the English and Irish ex pats who he had just been to visit. Not a pretty tale.
Decoding the genome was scratching the surface.
Nucleoside diphosphate kinase A (NME1) catalyses its own oligophosphorylation
https://www.nature.com/articles/s41557-025-01915-8
Protein phosphorylation is a central signalling mechanism in eukaryotic cells. The scope of this post-translational modification includes protein pyro- and polyphosphorylation. Here we report the discovery of another mode of phosphorylation: protein oligophosphorylation. Using site-specifically phosphorylated and pyrophosphorylated nucleoside diphosphate kinase A (NME1), the effects of these modifications on enzyme activity were investigated. Phosphorylation, and more so pyrophosphorylation, on Thr94 reduced the nucleoside diphosphate kinase activity. Nevertheless, both phosphoprotein and pyrophosphoprotein catalysed their own oligophosphorylation—up to the formation of a hexaphosphate chain—using ATP as a cofactor. Oligophosphorylation was critically dependent on the catalytic histidine residue His118, and cryogenic electron microscopy analysis of the modified proteins suggests an intramolecular phosphoryl transfer mechanism. Oligophosphorylation of NME1 in biochemical samples, and in cell lysates, was further confirmed using mass spectrometry, and was found to promote a new set of protein interactions. Our results highlight the complex nature of phosphoregulation, and the methods described here provide the opportunity to investigate the impact of this unusual modification in the future.
The sheer complexity of living cells that we know about is bad enough. God knows how much more there is to discover.
Do you still think you can control them?
(Up to now, Farage has done a pretty good job of that. But the stakes, temptations and pressures are quite a bit higher this time round.)
Dude just has a serious crush.
Trump: I was just sent a picture from somebody that wants to be there very badly. He has been very respectful of our country but not so respectful of others. I am going to sign this. Vladimir Putin. Who I believe will be coming. That was very nice
https://x.com/Acyn/status/1958945613678354894
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I also dont have any St George flags.
* Nigel Farage unveils his blueprint for the 'mass deportation' of hundreds of thousands of asylum seekers who come to the UK in small boats
* All those who come to the UK in small boats would be arrested and detained on disused military bases.. They would be barred from leaving until deportation
* Reform will seek to sign return deals with countries including Afghanistan and Eritrea, despite their human rights records
* Farage says Reform will charter five flights a day with an RAF Voyager on standby
* British Overseas Territories such as Ascension Island would be used as a "fallback" to accommodate migrants
* Reform will also seek to sign deals with third countries like Rwanda and Albania
* Reform would introduce new criminal offences for those attempting to return to the UK
* Farage's plan has three parts - leave ECHR and derogate from other international agreements, including UN convention against torture; bring in a British bill of rights; introduce the illegal migration (mass deportation) bill
* Reform says plans will cost £10bn over five years. It claims it will ultimately save taxpayers money
* Plans would face significant legal, political and practical obstacles
* Farage argues it is necessary to deal with the 'massive crisis' posed by illegal migration
* Pressed on what he would do if someone sent to Afghanistan was tortured or killed, Farage said: 'I’m really sorry, but we can’t be responsible for everything that happens in the whole of the world. Who is our priority?
'Is it the safety and security of this country and its people? Or are we worrying about everybody else and foreign courts? That’s what it comes down to. Whose side are you on?'
thetimes.com/uk/politics/ar…
https://x.com/steven_swinford/status/1958973895450440069?s=46&t=CW4pL-mMpTqsJXCdjW0Z6Q
Loyalist Volunteer Force
Orange Volunteers
Red Hand Commando
Red Hand Defenders
Ulster Defence Association
Ulster Freedom Fighters
Ulster Volunteer Force
are on the (Northern Ireland section of the) same proscribed list as Palestine Action. Flying a flag of one of them is illegal.
..Trump: “I was just sent a picture… I am going to sign this. Vladimir Putin. Who I believe will be coming. That was very nice.”
Reporter: Russia bombed a U.S. factory.
Trump: “I’m not happy about it.”
This entire press conference is bizarre AF...
https://x.com/CalltoActivism/status/1958949677220442267
*files it away carefully for Gazette editor*
All causes need a martyr. On examination, these martyrs are nearly always deeply flawed, but by then it doesn't matter, the narrative is put in place
Geo Floyd was a hideous career criminal, guilty of terrible things, yet the surge of emotion around his ugly death was sufficient to get him sanctified. For a while. In retrospect, I am not even sure he was murdered. I suspect he died because of his drug use more than the clearly unthinking and brutal copper
But no one cares now. The story is established, even as the emotions ebb
Lucy C is not as extremely bad as Floyd nor as extremely beatified as him, but there are definite parellels, and she will suffice as a martyr for the alt.right cause
The Union flags were looking quite pretty, backlit and glowing in the lowering early autumn sun, as I returned from the vineyard this evening.
Didn't we have rights before the ECHR enshrined in centuries of common law etc?
I'm not a lawyer.
The flag of the Orange Order. Not banned!
FPT Good evening, @Leon. Good thanks, hope you are too.
Apologies for the late reply. Was out with my Mum on a photo-walk (er, she's a member of not one but two of the local east London/Essex borders camera clubs), starting on Oxford St, Regent St, Carnaby St, Chinatown and Trafalgar. Let's just say the West End was rather busy, to put it mildly!
Anyway, in answer to your questions, and I feel I must apologise for writing an essay, but anyway: Nope, don't think your rude at all for asking about the flags! As for the Union Jack and St George's Cross, I do feel patriotic for both really. Certainly don't have a problem with with either of them. As you in this morning's thread, I saw a row of five flags (one row of many, in fact) hung across Oxford Street, and was eager to show all of you a picture on PB. And it's always nice to see pubs with the flags too (yes, we still have half a dozen or so in da North Ilford Ghetto!).
I think I have stated a couple of times on here that the most egregious, cruellest, pernicious aspect of the Empire was that the Powers That Be taught Indians how to play boring Cricket instead of Football. Imagine - India could now be the sporting Brazil of Asia! And I suppose Pakistan could be Argentina!
For me, England is my home, I've lived here ever since I was 4 months old. I do go back to India every couple of years, but I don't have any real attachment to the place. My language is English, and I have oft stated on here that I regard English as the best language in the world. One of the most disappointing things I find about India is the lack of civic sense in most parts of the country. Most obviously, the huge piles of litter beside train tracks and roads. No real neatness, as if tidiness isn't part of the culture. I could go on, but I digress!
Anyway, to conclude, perhaps very controversially, and this will probably upset a few PBers, I think that being English is a question of attitude, and not just a question of birth. Hope you find the above scrawlings interesting!
If flying a flag is done to celebrate or anticipate sporting achievement, fine. If to celebrate a national occasion, such as a Royal Jubilee or Wedding, St George's Day or anniversary of VJ day, also fine.
If it is done to intimidate or frighten, such as EDL marches, then not fine.
The same of course goes for other flags of course, including Palestine, Israel, Confederate, Betsy Ross, Soviet etc.
It is a race to see who can be first to just say 'burn it all down, every last fucking thing. Burn it.'
Douglas Carswell🇬🇧🇺🇸
@DouglasCarswell
Lucy Connolly judge Rahim Khimani refusal to grant bail was key to her coercion by the British state.
He should be sanctioned by the US government, with all that that entails
https://x.com/DouglasCarswell/status/1958932614452322625
That's a very considered and elegant reply. And, also, very useful
I'll refrain from any instant political reaction - not least because this reply is so nuanced, it deserves real reflection
https://www.telegraph.co.uk/politics/2025/08/22/suspend-echr-pave-way-migrant-deportations-blunkett-starmer/
The Shinners ex-little-helpers are much the same.
We live in interesting times
I also like Warks and Staffs.
Lincolnshire flag is hideous. Unsurprisingly it was selected via an online BBC vote.
Where, I wonder, is the next set of decent thoughts in the Burkean tradition going to come from?
I remember seeing a Somalian flag one time when driving through the Scottish Borders. Most diverting!
I'd consider flying a Hapsburg flag, but everyone would assume I had a Kilkenny flag rotated 90 degrees.
https://www.theguardian.com/technology/2025/aug/22/ai-chatgpt-new-model-grief
There is going to be gold rush for grief counseling specializing in AI model loss.
I went to some of Scruton's lectures at Birkbeck in the 80s as a callow smack addict Philosophy student. What a mind
His guide to Modern Philosophy is perhaps the smartest book I have ever read: in that it took the most difficult and arcane of ideas (but important) and made them legible to an intelligent layman. That is an amazing gift, very very few have it
Also he liked sex and wine. He was the last great English intellectual. Yes I am a fanboi. RIP